Model-Based Automatic Target Recognition (ATR) System for Forwardlooking Groundbased and Airborne Imaging Laser Radars (LADAR)

in Proceedings of the IEEE (1996), 84(2), 126-163

Model-Based Automatic Target Recognition Sys- tem for the UGV/RSTA Ladar: Status at Demo C

Conference (1996, February)

Model-based cardiac diagnosis of pulmonary embolism

in Computer Methods & Programs in Biomedicine (2007), 87(1), 46-60

A minimal cardiac model has been shown to accurately capture a wide range of cardiovascular system dynamics commonly seen in the intensive care unit (ICU). However, standard parameter identification ... [more ▼]

A minimal cardiac model has been shown to accurately capture a wide range of cardiovascular system dynamics commonly seen in the intensive care unit (ICU). However, standard parameter identification methods for this model are highly non-linear and non-convex, hindering real-time clinical application. An integral-based identification method that transforms the problem into a linear, convex problem, has been previously developed, but was only applied on continuous simulated data with random noise. This paper extends the method to handle discrete sets of clinical data, unmodelled dynamics, a significantly reduced data set theta requires only the minimum and maximum values of the pressure in the aorta, pulmonary artery and the volumes in the ventricles. The importance of integrals in the formulation for noise reduction is illustrated by demonstrating instability in the identification using simple derivative-based approaches. The cardiovascular system (CVS) model and parameter identification method are then clinically validated on porcine data for pulmonary embolism. Errors for the identified model are within 10% when re-simulated and compared to clinical data. All identified parameter trends match clinically expected changes. This work represents the first clinical validation of these models, methods and approach to cardiovascular diagnosis in critical care. (c) 2007 Elsevier Ireland Ltd. All rights reserved. [less ▲]

Model-based cardiovascular monitoring of acute pulmonary embolism in porcine trials

in Critical Care: the Official Journal of the Critical Care Forum (2011), 15 (Suppl 1)

Model-based Cardiovascular Therapeutics: Capturing the patient-specific impact of inotrope therapy

in Proceedings of the 3rd International Meeting of the French Society of Hypertension (2009)

Model-based detection of pulmonary embolism using an extended physiologically relevant, cardiovascular model

in Proceedings of Engineering & Physical Sciences in Medicine and Australian Biomedical Engineering Conference (EPSM ABEC 2008) (2008)

Model-based diagnosis of acute pulmonary embolism and septic shock in porcine trials

in Proceedings of the Health Research Society of Christchurch Annual Scientific Session 2011 (2011)

Model-based glycemic control in critical care

Poster (2012, December)

Model-based identification and diagnosis of a porcine model of induced endotoxic shock with hemofiltration

in Mathematical Biosciences (2008), 216(2), 132-139

Model-based Monitoring of Septic Shock Treated with Large-Pore Hemofiltration Therapy

in Proceedings of BMS 2012 (2012)