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See detailThe First Cities in the Near East
Van der Stede, Véronique ULg

Conference (2002, April 03)

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See detailFirst Clarkforkian equivalent land mammal age in the latest Paleocene basal Sparnacian facies of Europe: Fauna, flora, paleoenvironment and (bio)stratigraphy
Smith, T.; Quesnel, F.; De Plöeg, G. et al

in PLoS ONE (2014), 9(1),

The Paleocene-Eocene Thermal Maximum (PETM) is correlated with the first occurrences of earliest modern mammals in the Northern Hemisphere. The latest Paleocene Clarkforkian North American Land Mammal Age ... [more ▼]

The Paleocene-Eocene Thermal Maximum (PETM) is correlated with the first occurrences of earliest modern mammals in the Northern Hemisphere. The latest Paleocene Clarkforkian North American Land Mammal Age, that has yielded rodents and carnivorans, is the only exception to this rule. However, until now no pre-PETM localities have yielded modern mammals in Europe or Asia. We report the first Clarkforkian equivalent Land Mammal Age in the latest Paleocene deposits of the basal Sparnacian facies at Rivecourt, in the north-central part of the Paris Basin. The new terrestrial vertebrate and macroflora assemblages are analyzed through a multidisciplinary study including sedimentologic, stratigraphic, isotopic, and palynological aspects in order to reconstruct the paleoenvironment and to evaluate biochronologic and paleogeographic implications. The mammals are moderately diverse and not abundant, contrary to turtles and champsosaurs. The macroflora is exceptional in preservation and diversity with numerous angiosperms represented by flowers, fruits, seeds and wood preserved as lignite material, revealing an abundance of Arecaceae, Betulaceae, Icacinaceae, Menispermaceae, Vitaceae and probably Cornaceae. Results indicate a Late Paleocene age based on carbon isotope data, palynology and vertebrate occurrences such as the choristoderan Champsosaurus, the arctocyonid Arctocyon , and the plesiadapid Plesiadapis tricuspidens. However, several mammal species compare better with the earliest Eocene. Among these, the particular louisinid Teilhardimys musculus, also recorded from the latest Paleocene of the Spanish Pyrenees, suggests a younger age than the typical MP6 reference level. Nevertheless, the most important aspect of the Rivecourt fauna is the presence of dental remains of a rodent and a "miacid" carnivoran, attesting to the presence of two modern mammalian orders in the latest Paleocene of Europe. Interestingly, these two groups are also the only modern groups recorded from the latest Paleocene of North America, making Rivecourt the first direct equivalent to the Clarkforkian Land Mammal Age outside of North America. © 2014 Smith et al. [less ▲]

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See detailFirst clinical results of licofelone (ml3000), an inhibitor of COX-1, COX-2 and 5-LOX, for the treatment of osteoarthritis
Reginster, Jean-Yves ULg; Bias, P.; Buchner, A.

in Annals of the Rheumatic Diseases (2002, June), 61(Suppl.1),

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See detailFirst come first served: “priority effect“ benefits Ambrosia artemisiifolia L. more than other ruderal Asteraceae species
Ortmans, William ULg; Mahy, Grégory ULg; Monty, Arnaud ULg

Poster (2016, September 14)

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of ... [more ▼]

Ambrosia artemisiifolia L. (common ragweed, Asteraceae) is an invasive weed causing a health crisis in Europe, due to its highly allergenic pollen. In Western Europe the invaded range covers most of central and southern France, and northern Italy. Northwards beyond the edge of this range, occurrence of casual population have been described for years, but these populations do not appear to become invasive, and the species does not seem to spread. This situation raises the following question: Has the invaded range reached a limit or will the species continue its invasion northwards? To answer this question, we followed two complementary approaches. First we set up an experimental garden in Belgium, 250 km north to the current invaded range, to see if the local climate allows the completion of the species reproduction cycle. Second, we performed an in situ measurement campaign in 12 population located beyond the edge, within the range but near the margin, and in the center of the invaded range. The aim of this campaign was to test whether the species had reduced plant performance towards range margins. The results showed that the species is able to establish populations with high growth rates in Belgium. Furthermore, the species expressed similar performance across the considered areas, even beyond the current invasion front. No evidence of processes constraining the invasion was found, which suggests a great potential for invasion north to the current invaded range. In this uncertain situation, awareness actions should be considered in the northern countries. [less ▲]

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See detailThe first community forests of Gabon : towards sustainable local forest management ?
Meunier, Quentin ULg; Federspiel, Michèle; Moumbogou, Carl et al

in Nature et Faune (2011), 25(2), 40-45

Forest resources abound in Gabon. Species diversity and quality of trees in the Gabonese forests make it a very lucrative production niche. Even though international forest operators are well established ... [more ▼]

Forest resources abound in Gabon. Species diversity and quality of trees in the Gabonese forests make it a very lucrative production niche. Even though international forest operators are well established there and are making profit, the Gabonese rural communities have not yet developed their own operations. In view of their remoteness from decision-making centers, villagers often unlawfully lose, without being aware of it, a great deal of the riches in their villages. Today, the rural socio-economic component is not sufficiently integrated in the management factors of the resource, even though populations that depend on them daily are supposedly the best placed individuals to make wise use of them. In this sense, community forestry helps to promote sustainable use of forest resources at a scale that is at par with the needs of the community, and seeks to guarantee that profits are shared at village level. In Gabon, the process of legalization of community forests is ongoing since 2001. Pilot projects such as DACEFI (Development of Community Alternatives to Illegal Logging) strive to assist communities in securing their community forest. However their legalization is slow in coming, while logging activities in the rural forest estate are increasing, and the quality of the species is deteriorating continually. [less ▲]

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See detailFirst conclusions from the Belgian stakeholder panel: FP 7 PREPARE, WG 3 “Consumer Goods”
Turcanu, Catrinel; Olyslaegers, Geert; Camps, Johan et al

Conference (2014, May)

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See detailThe first definite record of a Valanginian ichthyosaur and its implications on the evolution of post-Liassic Ichthyosauria
Fischer, Valentin ULg; Clément, Arnaud; Guiomar, Myette et al

in Cretaceous Research (2011), 32(2), 155-163

A complete ichthyosaur rostrum, with 124 associated teeth, was recently discovered in Laux-Montaux locality, department of Drôme, southeastern France. The associated belemnites and ammonites indicate a ... [more ▼]

A complete ichthyosaur rostrum, with 124 associated teeth, was recently discovered in Laux-Montaux locality, department of Drôme, southeastern France. The associated belemnites and ammonites indicate a late Valanginian age (Neocomites peregrinus Zone, Olcostephanus nicklesi Subzone) for this fossil, which consequently represents the first diagnostic ichthyosaur ever reported from Valanginian strata. This specimen also represents the first occurrence of Aegirosaurus outside the Tithonian (Upper Jurassic) lithographic limestones of Bavaria (southern Germany). Tooth morphology and wear pattern suggest that Aegirosaurus belonged to the “Pierce II/ Generalist” feeding guild, which was hitherto not represented in post-Liassic ichthyosaurs. Most Late Jurassic ichthyosaurs actually crossed the Jurassic-Cretaceous boundary. [less ▲]

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See detailA first detailed study of the colliding wind WR+O binary WR 30a
Gosset, Eric ULg; Royer, P.; Rauw, Grégor ULg et al

in Monthly Notices of the Royal Astronomical Society (2001), 327

We present a detailed, extensive investigation of the photometric and spectroscopic behaviour of WR 30a. This star is definitely a binary system with a period around 4.6d. We propose the value P=4.619d ... [more ▼]

We present a detailed, extensive investigation of the photometric and spectroscopic behaviour of WR 30a. This star is definitely a binary system with a period around 4.6d. We propose the value P=4.619d (sigma=0.002d). The identification of the components as WO4+O5((f)) indicates a massive evolved binary system; the O5 component is a main-sequence or, more likely, a giant star. The radial velocities of the O star yield a circular orbit with an amplitude K[SUB]O[/SUB]=29.9 (sigma=2.1)kms[SUP]-1[/SUP] and a mass function of 0.013 (sigma=0.003)M[SUB]solar[/SUB]. The spectrum of WR 30a exhibits strong profile variations of the broad emission lines that are phase-locked with the orbital period. We report the detection of the orbital motion of the WO component with K[SUB]WO[/SUB]=189kms[SUP]-1[/SUP], but this should be confirmed by further observations. If correct, it implies a mass ratio M[SUB]WO[/SUB] /M[SUB]O[/SUB]=0.16. The star exhibits sinusoidal light variations of amplitude 0.024mag peak-to-peak with the minimum of light occurring slightly after the conjunction with the O star in front. On the basis of the phase-locked profile variations of the Civ lambda4658 blend in the spectrum of the WO, we conclude that a wind-wind collision phenomenon is present in the system. We discuss some possibilities for the geometry of the interaction region. [less ▲]

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See detailFirst detection of a transferable blaCTX-M-14b gene in a Klebsiella pneumoniae clinical isolate from Tunisia and analysis of its genetic context
Ben Achour, Nahed; Power, Pablo; Mercuri, Paola ULg et al

in Annals of Microbiology (2012), 62

Klebsiella pneumoniae ML2508 was isolated from a patient at the surgery unit of the Military Hospital (Hôpital Militaire de Tunis), Tunisia. It was identified as a producer of extended-spectrum β ... [more ▼]

Klebsiella pneumoniae ML2508 was isolated from a patient at the surgery unit of the Military Hospital (Hôpital Militaire de Tunis), Tunisia. It was identified as a producer of extended-spectrum β-lactamases (ESBLs) by the double-disk synergy test. The β-lactamases produced by the strain were characterized by isoelectric focusing, determination of the specific activities against penicillins and cephalosporins, determination of the inhibitory concentration required to inhibit 50% of enzyme activity (IC50), and the inhibition effect of EDTA on putative metallo-β-lactamases. The crude extract of K. pneumoniae ML2508 contains five different β-lactamases with pI 5.5, 7.3, 7.6, 8.1, and 8.6. Only the β-lactamase with pI 8.1 was transferred by transformation and conjugation experiments. Molecular characterization of these genes was performed by PCR and sequencing. The four chromosomal β-lactamases are TEM (pI 5.5), 2 SHV (pI 7.3 and 7.6), and CTX-M-28 (pI 8.6). The β-lactamase with pI 8.1 was encoded byblaCTX-M-14b gene located on a 50-kb highly conjugative plasmid. The study of the genetic context of blaCTX-M-14b was realized by PCR mapping and DNA sequencing. A novel variant of tnpISEcp1 designated ISEcp1C was detected upstream of the gene. [less ▲]

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See detailFirst detection of CTX-M-28 in a Tunisian hospital from a cefotaxime-resistant Klebsiella pneumoniae strain.
Ben Achour, N.; Mercuri, Paola ULg; Power, P. et al

in Pathologie-biologie (2009), 57(5), 343-8

A cefotaxime-resistant Klebsiella pneumoniae ML4313 was obtained from a patient from intensive care unit of Military hospital in Tunisia. This strain was resistant to beta-lactams, aminoglycosides ... [more ▼]

A cefotaxime-resistant Klebsiella pneumoniae ML4313 was obtained from a patient from intensive care unit of Military hospital in Tunisia. This strain was resistant to beta-lactams, aminoglycosides, quinolones and phenicols, and tetracyclines. It was identified as producer of extended-spectrum beta-lactamases (ESBL) by double-disk synergy test between amoxicillin-clavulanate and cefotaxime, ceftriaxone, ceftazidime and aztreonam. The ESBL was identified as CTX-M-28 by sequencing of PCR products and by isoelectric focusing. The ESBL resistance was transferred by a 50kb plasmid. CTX-M-28 is closely related to CTX-M-15. This is the first description of this enzyme in Tunisia. [less ▲]

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See detailFirst detection of hydroxyl in the atmosphere of Venus
Piccioni, G.; Drossart, P.; Zasova, L. et al

in Astronomy and Astrophysics (2008), 483

Context: Airglow emissions, such as previously observed from NO and O2(a-X) (0-0) on Venus, provide insight into the chemical and dynamical processes that control the composition and energy balance in the ... [more ▼]

Context: Airglow emissions, such as previously observed from NO and O2(a-X) (0-0) on Venus, provide insight into the chemical and dynamical processes that control the composition and energy balance in the upper atmospheres of planets. The OH airglow emission has been observed previously only in the Earth's atmosphere where it has been used to infer atomic oxygen abundances. The O2(a-X) (0-1) airglow emission also has only been observed in the Earth's atmosphere, and neither laboratory nor theoretical studies have reached a consensus on its transition probability. Aims: We report measurements of night-side airglow emission in the atmosphere of Venus in the OH (2-0), OH (1-0), O2(a-X) (0-1), and O2(a-X) (0-0) bands. This is the first detection of the first three of these airglow emissions on another planet. These observations provide the most direct observational constraints to date on H, OH, and O3, key species in the chemistry of Venus' upper atmosphere. Methods: Airglow emission detected at wavelengths of 1.40-1.49 and 2.6-3.14 mum in limb observations by the Visible and Infrared Thermal Imaging Spectrometer (VIRTIS) on the Venus Express spacecraft is attributed to the OH (2-0) and (1-0) transitions, respectively, and compared to calculations from a photochemical model. Simultaneous limb observations of airglow emission in the O2(a-X) (0-0) and (0-1) bands at 1.27 and 1.58 mum, respectively, were used to derive the ratio of the transition probabilities for these bands. Results: The integrated emission rates for the OH (2-0) and (1-0) bands were measured to be 100 ± 40 and 880±90 kR respectively, both peaking at an altitude of 96 ± 2 km near midnight local time for the considered orbit. The measured ratio of the O2(a-X) (0-0) and (0-1) bands is 78 ± 8. Conclusions: Photochemical model calculations suggest the observed OH emission is produced primarily via the Bates-Nicolet mechanism, as on the Earth. The observed ratio of the intensities of the O2(a-X) (0-0) and (0-1) bands implies the ratio of their transition probabilities is 63±6. [less ▲]

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See detailFirst detection of phase-dependent colliding wind X-ray emission outside the Milky Way
Nazé, Yaël ULg; Corcoran, M. F.; Koenigsberger, G. et al

in Astrophysical Journal (2007), 658(1, Part 2), 25-28

After having reported the detection of X-rays emitted by the peculiar system HD 5980, we assess here the origin of this high-energy emission from additional X-ray observations obtained with XMM-Newton ... [more ▼]

After having reported the detection of X-rays emitted by the peculiar system HD 5980, we assess here the origin of this high-energy emission from additional X-ray observations obtained with XMM-Newton. This research provides the first detection of apparently periodic X-ray emission from hot gas produced by the collision of winds in an evolved massive binary outside the Milky Way. It also provides the first X-ray monitoring of a luminous blue variable only years after its eruption and shows that the dominant source of the X-rays is not associated with the ejecta. After having reported the detection of X-rays emitted by the peculiar system HD 5980, we assess here the origin of this high-energy emission from additional X-ray observations obtained with XMM-Newton. This research provides the first detection of apparently periodic X-ray emission from hot gas produced by the collision of winds in an evolved massive binary outside the Milky Way. It also provides the first X-ray monitoring of a luminous blue variable only years after its eruption and shows that the dominant source of the X-rays is not associated with the ejecta. [less ▲]

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See detailFirst detection of resistance to QOI fungicides in Mycosphaerella graminicola on winter wheat in Belgium
Amand, O.; Calay, F.; Coquillart, L. et al

in Communications in Agricultural and Applied Biological Sciences (2003, May 06), 68(4b), 519-531

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See detailFirst Direct Assay for Intact Human Proinsulin
Houssa, P.; Dinesen, B.; Deberg, Michelle ULg et al

in Clinical Chemistry (1998), 44(7), 1514-9

We describe a sensitive two-site sandwich enzyme-linked immunosorbent assay for the measurement of intact human proinsulin in 100 microL of serum or plasma. The assay is based on the use of two monoclonal ... [more ▼]

We describe a sensitive two-site sandwich enzyme-linked immunosorbent assay for the measurement of intact human proinsulin in 100 microL of serum or plasma. The assay is based on the use of two monoclonal antibodies specific for epitopes at the C-peptide/insulin A chain junction and at the insulin B chain/C-peptide junction, respectively. Cross-reactivities with insulin, C-peptide, and the four proinsulin conversion intermediates were negligible. The detection limit in buffer was 0.2 pmol/L (3 standard deviations from zero). The working range was 0.2-100 pmol/L. The mean intra- and interassay coefficients of variation were 2.4% and 8.9%, respectively. The mean recovery of added proinsulin was 103%. Dilution curves of 40 serum samples are parallel to the proinsulin calibration curve. Proinsulin concentrations in 20 fasting healthy subjects were all above the limit of detection: median (range), 2.7 pmol/L (1.1-6.9 pmol/L). Six fasting non-insulin-dependent diabetes mellitus and five insulinoma patients had proinsulin concentrations significantly higher than healthy subjects: median (range), 7.7 pmol/L (3.2-18 pmol/L) and 153 pmol/L (98-320 pmol/L), respectively. [less ▲]

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See detailFirst do not harm
Jamoulle, Marc ULg

in Journal of Mid-life Health (2015), 6(2), 51-52

commentary on Kalra B, Malik S. Quaternary prevention and menopause. J Midlife Health 2014;5:53-4.

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See detailFirst epidemiological data on pathogenic leptospires isolated on the Azorean islands
Collares-Pereira, Margarida; Korver, H.; Terpstra, W. J. et al

in European Journal of Epidemiology (1997), 13

Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores archipelago were found to carry three distinct Leptospira interrogans s ... [more ▼]

Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores archipelago were found to carry three distinct Leptospira interrogans s.l. serovars (copenhageni, icterohaemorrhagiae and ballum) which have never been previously investigated there. The house mouse and the black rat were the major Leptospira reservoir showing isolation rates ranging from 0% for both species (in Graciosa) to 88 % and 33 %, respectively (in São Miguel). This study also showed that the majority of the animals with positive kidney cultures exhibited specific agglutinins agaibst the isolated strains of Leptospira. The observed isalation rates in the different islands, with a very interesting island variation in prevalence, suggest that small mammals, serving as sylvatic reservoirs of pathogenic leptospires, may represent an important risk to the health of humans and the livestock, particularly in the islands of Terceira and São Miguel. [less ▲]

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See detailFirst epidemiological study on exposure to Neospora caninum in different canine populations in the Algiers District (Algeria)
Ghalmi, F.; China, B.; Kaïdi, R. et al

in Parasitology International (2009), 58(4), 444-450

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