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See detailInterdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate
Sapunaric, Frédéric ULg; Levy, Stuart B.

in Antimicrobial Agents and Chemotherapy (2007)

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See detailInterdomain Traffic Engineering in a Locator/Identifier Separation Context
Saucez, Damien; Donnet, Benoît ULg; Iannone, Luigi et al

in IEEE Internet Network Management Workshop (2008, October)

The Routing Research Group (RRG) of the Internet Research Task Force (IRTF) is currently discussing several architectural solutions to build an interdomain routing architecture that scales better than the ... [more ▼]

The Routing Research Group (RRG) of the Internet Research Task Force (IRTF) is currently discussing several architectural solutions to build an interdomain routing architecture that scales better than the existing one. The solutions family currently being discussed concerns the addresses separation into locators and identifiers, LISP being one of them. Such a separation provides opportunities in terms of traffic engineering. In this paper, we propose an open and flexible solution that allows an ISP using identifier/locator separation to engineer its interdomain traffic. Our solution relies on the utilization of a service that transparently ranks paths using cost functions. We implement a prototype server and demonstrate its benefits in a LISP testbed. [less ▲]

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See detailInterest and feasibility of a modified supine position for posterior cranial fossa surgical procedures.
Graftieaux, J-P; Litré, Claude Fabien ULg; Gomis, P et al

in Annales Françaises d'Anesthésie et de Réanimation (2004)

The sitting position is considered as a gold standard for posterior fossa surgical procedures. However, in order to decrease the incidence rate of cerebral venous air embolisms, we presently described a ... [more ▼]

The sitting position is considered as a gold standard for posterior fossa surgical procedures. However, in order to decrease the incidence rate of cerebral venous air embolisms, we presently described a modified supine position allowing performance of posterior fossa surgical procedures. Such position is easy and quickly performed with light variations of blood pressure: patients are placed supine with paddings inserted under ipsilateral shoulder and buttock, and head turned to other side of surgical site. Dural tension estimated by the surgeon was always considered as good. We performed more than 100 surgical procedures in this position without any complication for 10 years. [less ▲]

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See detailInterest in measuring endothelin (ET1) in cardiovascular pathology, hypertension and uremia
Dwelshauwers, J. M.; Krzesinski, Jean-Marie ULg; Rorive, Georges ULg

in Acta Clinica Belgica (1994), 49(6), 317

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See detailInterest of 5-hydroxytryptophan (5-HTP) test as a neuroendocrine marker of endogenous depression
Ansseau, Marc ULg; Doumont, Adrienne; Thiry, Daniel et al

in Acta Psychiatrica Belgica (1983), 83

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See detailInterest of a comparative proteomic approach to unravel the aetiology of DOMS in humans
Hody, Stéphanie ULg; Croisier, Jean-Louis ULg; WANG, François-Charles ULg et al

in Abstract Book of Proteom’ Lux 2007 (2007, October)

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See detailInterest of a comparative proteomic approach to unravel the aetiology of DOMS in humans
Hody, Stéphanie ULg; Croisier, Jean-Louis ULg; Wang, François-Charles ULg et al

in Acta Physiologica Scandinavica. Supplementum (2008), 194(suppl 666), -09

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See detailInterest of a prescreening questionnaire to reduce the cost of bone densitometry
Ben Sedrine, Wafa ULg; Broers, P; Devogelaer, JP et al

in Clinical Rheumatology (2001), 20

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See detailInterest of a prescreening questionnaire to reduce the cost of bone densitometry
Ben Sedrine, Wafa ULg; Broers, P.; Devogelaer, J. P. et al

in Osteoporosis International (2002), 13(5), 434-442

Bone mineral density (BMD) measurement is widely recognized as the best single tool to identify patients with a high lifetime risk of developing an osteoporosis-related fracture. However, the cost/benefit ... [more ▼]

Bone mineral density (BMD) measurement is widely recognized as the best single tool to identify patients with a high lifetime risk of developing an osteoporosis-related fracture. However, the cost/benefit value of screening the whole population has been repeatedly challenged and demonstrated to be rather poor. In many countries, BMD scan is not or no longer reimbursed because of lack of validated criteria to identify patients who should benefit from this procedure. Based on the proposals of a nationwide expert panel, a simple questionnaire identifying historical, clinical and behavioral risk factors for osteoporosis was developed. The aim of this study was to assess the diagnostic accuracy of the proposed criteria; to determine the extent to which this questionnaire could be useful for optimizing the use of densitometry tests; and, more specifically, to estimate the diagnostic costs per osteoporotic or osteopenic patient detected. For this purpose, we applied the questionnaire to 3998 consecutive individuals at least 20 years old, of both genders, either consulting spontaneously or referred for a BMD measurement to an outpatient osteoporosis center. BMD was measured by dual-energy X-ray absorptiometry (DXA) at the lumbar spine and at the hip (both total hip and femoral neck). Diagnostic accuracies were evaluated through measures of sensitivity, specificity, and positive and negative predictive values. After determining a benchmark value for age, different strategies were compared in order to identify the most cost-effective one in terms of cost per patient detected. According to the WHO operational definition of osteoporosis (T-score <-2.5), 31% of the subjects were classified as osteoporotic at one or more of the measured sites. If only patients with at least one of the proposed risk factors had been referred for scans, 33.3% of the BMD measurements would have been avoided. Among those, less than 5% were missclassified as they did have osteoporosis at the total hip and up to 23% at one or more of the considered sites. On the other hand, of the subjects who would be recommended for a densitometry test, only a small fraction were identified correctly (the positive predictive values varied from 11.3% at the total hip to 34.8% at any site). In this first setting, the suggested criteria seem useful chiefly for excluding subjects who do not need a DXA scan rather than selecting osteoporotic patients. When applied only to patients aged 61 years or more, the positive predictive values rose to 15.1% (total hip) and 42.9% (any site), whereas the corresponding negative predictive values were set at 93% and 68.6%. In comparison, with a mass screening scenario the estimated diagnostic costs (costs associated with the DXA procedure) per osteoporotic patient detected at any of the considered sites would be reduced by more than 9% (59.4 instead of 65.3 Euros) if the suggested indications are taken into account for prescreening patients. And when the questionnaire is applied only to women over the age of 60 years these costs would be further reduced to 50.6 Euros, representing a 23% decrease. Then, a prescreening strategy based on these indications concomitantly with an age-selective criterion could represent a promising way toward a more rational use of BMD measurement. [less ▲]

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See detailInterest of a simple pre-screening test for optimazing the cost/benefit value of bone densitometry
Ben Sedrine, Wafa ULg; Broers, P; Brands, G et al

in Arthritis and Rheumatism (1999), 42(S1), 289

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See detailInterest of a simple pre-screening test for optimizing the cost/benefit value of bone densitometry
Ben Sedrine, Wafa ULg; Broers, Ph; Brands, G et al

in Osteoporosis International (2000), SS(S5), 13

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See detailInterest of a specific training to reduce DOMS
Croisier, Jean-Louis ULg; Camus, Gérard; Crielaard, Jean-Michel ULg

in Isokinetics & Exercise Science (2000, March), 8

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See detailInterest of biochemical markers of bone turnover for long-term prediction of new vertebral fracture in postmenopausal osteoporotic women
Bruyère, Olivier ULg; Collette, Julien ULg; Delmas, Pierre et al

in Maturitas (2003), 44(4), 259-265

Objective: To analyse the interest of baseline levels and short-term (3-months) changes in serum osteocalcin (BGP), serum bone-specific alkaline phosphatase (BALP) and urinary C-telopeptide of type I ... [more ▼]

Objective: To analyse the interest of baseline levels and short-term (3-months) changes in serum osteocalcin (BGP), serum bone-specific alkaline phosphatase (BALP) and urinary C-telopeptide of type I collagen/creatinine ratio (U-TX) to predict 3-years changes in bone mineral density (BMD) and spinal deformity index (SDI) in postmenopausal osteoporotic women. Methods: Data were derived from a cohort of 603 osteoporotic women corresponding to the placebo arm of a 3-years prospective, double-blind study. Results: Baseline values of BALP, BGP and U-CTX were negatively and significantly correlated with baseline spinal BMD. Significant correlations were also observed between the changes in BMD observed after 36 months at the spine and baseline BALP (r = 0.20, P = 0.0001), BGP (r = 0.09, P = 0.05) and U-CTX (r = -0.11, P = 0.02). At 3 years, 71 women (15.9%) showed an increase in their SDI, corresponding to the occurrence of at least one new vertebral deformity. Baseline values of the four bone turnover markers (BTM) were not significantly related to the occurrence of new vertebral deformities. However, when considering the changes in the BTM observed after 3-months of follow-up, BGP (P = 0.003) and U-CTX (P = 0.047) were identified as significant predictors of an increase of SDI. The associated odds ratios (95% confidence interval (CI)) were 10.922 (2.218-53.78) for unit changes of log BGP and 1.369 (1.003-1.867) for unit changes of log U-CTX. The relative risk (RR) (IC 95%) of having a new vertebral fracture over 36 months was 0.31 (0.15-0.65) when being in the lowest quartile of 3-months changes in BGP as compared with the highest. Conclusion: We conclude that two sequential measurements of BGP and U-CTX performed at 3-months intervals could be of interest to identify postmenopausal osteoporotic women with the highest risk to present new vertebral deformities. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]

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See detailInterest of cerebral Doppler in neonates
Battisti, Oreste ULg

Conference given outside the academic context (1993)

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See detailInterest of DOC in the study of consciousness
Vanhaudenhuyse, Audrey ULg

Conference (2007)

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See detailInterest of Face Mask--Cpap in One Case of Severe Accidental Hypothermia
Canivet, Jean-Luc ULg; Larbuisson, Robert ULg; Lamy, Maurice ULg

in Acta Anaesthesiologica Belgica (1989), 40(4), 281-3

one case of severe accidental hypothermia; rectal temperature was 25 degrees C. Hypoxemia unmodified by 100 O2 inhalation in an ordinary face-mask was easily corrected using a face-mask CPAP; a ... [more ▼]

one case of severe accidental hypothermia; rectal temperature was 25 degrees C. Hypoxemia unmodified by 100 O2 inhalation in an ordinary face-mask was easily corrected using a face-mask CPAP; a ventilation-perfusion mismatching could be implicated in the cold induced hypoxemia. Active rewarming (1.5 degrees C/h) was pursued from 25 to 37 degrees C, using non aggressive methods: warming blankets and a Bennett heated humidifier inserted in the CPAP system. Even in severe hypothermia successful results may be obtained without resort to sophisticated methods. [less ▲]

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See detailInterest of Health Economic Analyses
Hiligsmann, Mickaël ULg

Conference given outside the academic context (2011)

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