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See detailIngénierie génétique d'une β2-intégrine LFA-1 bovine résistante à la leucotoxine de Mannheimia haemolytica
Fett, Thomas ULg

Doctoral thesis (2012)

Domesticated bovines are known since decades to be prone to bacterial pneumonias. Among the causative agents, a consensus emerged stating that Mannheimia haemolytica is the most frequent bacterium ... [more ▼]

Domesticated bovines are known since decades to be prone to bacterial pneumonias. Among the causative agents, a consensus emerged stating that Mannheimia haemolytica is the most frequent bacterium isolated from bovine lungs throughout the world. Moreover, it appeared that its virulence specifically targets ruminant lungs in vivo and ruminant leucocytes in vitro. When the thesis was started, the two main actors underlying this species-specific virulence were known: the leukotoxin (LKT) on the pathogen side and the beta2-integrin LFA-1 on the host side. The objective of the thesis was to contribute to the understanding of the LKT/LFA 1 interaction at the molecular level. Using a between-species perspective, we showed that (i) the CD11a subunit of the LFA-1 heterodimer was not involved in the LKT-specificity for ruminant LFA-1, (ii) the EGF-3 module within the CD18 controls the susceptibility of any given CD18 to LKT and (iii) a non cleavable signal peptide conjugated to a LKT susceptible EGF-3-containing CD18 exacerbates LKT pronecrotic effects. [less ▲]

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See detailIngenierie genetique. Strategie et perspectives en agronomie.
Portetelle, Daniel ULg; Burny, A.; Hilger, F.

Book (1981)

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See detailL'ingénierie patrimoniale dans les relations franco-belges : perspective de droit international privé belge
Wautelet, Patrick ULg

in Derème, François (Ed.) Ingénierie patrimoniale. Questions particulières dans un contexte franco-belge (2009)

In this paper I review the possibilities offered by private international rules in force both in Belgium and in France for three selected tools of estate planning : the marriage contract, gift and ... [more ▼]

In this paper I review the possibilities offered by private international rules in force both in Belgium and in France for three selected tools of estate planning : the marriage contract, gift and donation and wills. The purpose is to examine how much freedom the legal framework in place in the two countries offers to private individuals. Specific attention is devoted to the issue of recognition in one country of acts (such as marriage contracts) drafted in the other country. [less ▲]

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See detailL'ingénierie patrimoniale dans les relations franco-belges : perspectives de droit international privé belge
Wautelet, Patrick ULg

in Dereme, François (Ed.) Ingénierie patrimonial. Questions particulières dans un contexte franco-belge (2013)

Cette contribution s'attache aux questions de droit international privé qui peuvent intéresser la pratique des relations patrimoniales franco-belges. Elle présente succinctement les lignes de force de la ... [more ▼]

Cette contribution s'attache aux questions de droit international privé qui peuvent intéresser la pratique des relations patrimoniales franco-belges. Elle présente succinctement les lignes de force de la réglementation de droit international privé dans les principales branches susceptibles d'intéresser le praticien. L'optique étant celle de la planification successorale, la contribution met l'accent sur l'espace de liberté dont disposent les parties. Plus précisément, la question qui fera figure de fil rouge est celle de savoir quelle marge de manœuvre le droit international privé accorde aux parties qui envisagent l'une ou l'autre opération patrimoniale. Cette question est abordée à propos de trois grands moments de la vie : le mariage et les relations qui y sont assimilées, le décès et les libéralités à cause de vif. [less ▲]

Detailed reference viewed: 71 (2 ULg)
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See detailIngenierie tissulaire du parenchyme renal : une hypothese therapeutique ?
JOURET, François ULg; Pirson, Yves

in Medecine Sciences : M/S (2008), 24(6-7), 561-3

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See detailL'ingénieur et la résistance au feu en Belgique
Franssen, Jean-Marc ULg

Scientific conference (1998, March 04)

Detailed reference viewed: 7 (1 ULg)
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See detailL'ingénieur et son art. Défi de la R&D et défi du marché
Vankerkem, Michel; Claustriaux, Jean-Jacques ULg; et al.

in Gestion 2000 (1994), 4

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See detailLes ingénieurs chimistes et leurs instruments: Le cas de l'analyse polarimétrique dans l'industrie sucrière
Melard, François ULg

in Chimie Nouvelle (1999), 17(68), 3008-3011

This article put forward the complexe relations that exists between chemists ingeneers and the development of the Sugar industry in Belgium (in the 19s century). The argument is that the technical ... [more ▼]

This article put forward the complexe relations that exists between chemists ingeneers and the development of the Sugar industry in Belgium (in the 19s century). The argument is that the technical dimension of the implementation of a new chemical protocol for the delivery of sugar beets may be of some importance in order to understand the sociological dimension of contractual relations between actors and the role of scientific expertise in such a context. [less ▲]

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See detailIngérence, vous avez dit ingérence.
Hanzen, Christian ULg

Speech (2008)

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See detailIngestibilité et valeur alimentaire des foins issus de prairies de haute valeur biologique
Decruyenaere, Virginie; Houba, Quentin; Stilmant, Didier et al

Article for general public (2009)

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See detailIngestibilité et valeur alimentaire des foins issus de prairies de haute valeur biologique.
Decruyenaere, Virginie; Houba, Quentin; Stilmant, Didier ULg et al

in XVes Rencontres recherches ruminants (2008)

Detailed reference viewed: 43 (6 ULg)
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See detailIngestion and metabolic profile in horses offered lucerne or chalk as a source of calcium
de Behr, V.; Daron, D.; Gabriel, Annick ULg et al

in Proceedings of the British Society of Animal Science (2002)

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See detailInhalation therapy of equine respiratory disorders
Duvivier, D. H.; Votion, Dominique ULg; Roberts, C. A. et al

in Equine Veterinary Education (1999), 11(3), 124-130

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See detailInhalation with NDS27 attenuates pulmonary neutrophilic inflammation in recurrent airway obstruction
Sandersen, Charlotte ULg; Olejnik, Dorine; Franck, Thierry ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2011)

Detailed reference viewed: 56 (23 ULg)
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See detailInhaled and systemic corticosteroids decrease Matrix Metalloproteinase-9 in bronchoalveolar lavage fluid of asthmatic cats
Leemans, Jérôme ULg; Kirschvink, Nathalie; Delvaux, François ULg et al

in In Proceedings:15th Congress European College of Veterinary Internal Medicine – companion animals (2005)

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See detailInhaled corticosteroids effects on bone in asthmatic and COPD patients: a quantitative systematic review
Richy, Florent; Bousquet, Jean; Ehrlich, George E et al

in Osteoporosis International (2003), 14(3), 179-190

Deleterious effect of oral corticosteroids on bone has been well documented, whereas this remains debated for inhaled ones (ICS). Our objectives were to analyze the effects of ICS on bone mineral density ... [more ▼]

Deleterious effect of oral corticosteroids on bone has been well documented, whereas this remains debated for inhaled ones (ICS). Our objectives were to analyze the effects of ICS on bone mineral density, fracture risk and bone markers. We performed an exhaustive systematic research of all controlled trials potentially containing pertinent data, peer-reviewed by a dedicated WHO expert group, and comprehensive meta-analyses of the data. Inclusion criteria were ICS, and BMD/markers/fractures in asthma/chronic obstructive pulmonary diseases (COPD) and healthy patients. Analyses were performed in a conservative fashion using professional dedicated softwares and stratified by outcome, study design and ICS type. Results were expressed as standardized mean difference/effect size (ES), relative risk (RR) or odds ratio (OR), depending on study design and outcome units. Publication bias was investigated. Twenty-three trials were reviewed; 11 papers fit the inclusion criteria and were assessed for the main analysis. Quality scores for the randomized controlled trials (RCTs) were 80%, 71% for the prospective cohort studies, and 78% for the retrospective cohort and cross-sectional studies. We globally assessed ICS effects on BMD and found deleterious effects: ES=0.61 (p=0.001) for healthy subjects, and ES=0.27 (p<0.001) for asthma/COPD patients. For these patients, this effect was 0.21 (p<0.01) at the lumbar spine, and 0.26 (p<0.001) at the hip or femoral neck. A single study evaluated the impact of ICS on hip fracture and reported an increased OR of 1.6 (1.24; 2.03). Lumbar fracture rate differences did not reach the level of statistical significance: 1.87 (0.5; 6.94). Osteocalcin and PICP were decreased and ICTP, pyridinoline and deoxypyridinoline levels were not significantly affected. Budesonide (BUD) appeared to be the ICS inducing the less deleterious effects on bone, followed by beclomethasone dipropionate (BDP) and triamcinolone (TRI). Publication bias investigation provided non-significant results. In our meta-analyses, BUD at a mean daily dose (SD) of 686 mug (158 mug), BDP at 703 mug (123 mug) and TRI at 1000 mug (282 mug) were found to affect bone mineral density and markers in patients suffering from the two major respiratory diseases. These findings could have practical implication in the long-term management of asthmatic and COPD patients. [less ▲]

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See detailInhaled corticosteroids effects on bone in asthmatic and COPD patients: what is the evidence?
Richy, Florent; Bousquet, Jean; Devogelaer, Jean-Pierre et al

in Osteoporosis International (2002, November), 13(Suppl.3), 22

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See detailInhaled fluticasone reduces bronchial responsiveness and airway inflammation in cats with mild chronic bronchitis
Kirschvink, N; Leemans, Jérôme ULg; Delvaux, François et al

in Journal of Feline Medicine and Surgery (2006), 8(1), 45-54

This study investigated the effect of inhaled fluticasone on lower airway inflammation and bronchial responsiveness (BR) to inhaled carbachol in cats with very mild, chronic bronchitis (n = 5) that were ... [more ▼]

This study investigated the effect of inhaled fluticasone on lower airway inflammation and bronchial responsiveness (BR) to inhaled carbachol in cats with very mild, chronic bronchitis (n = 5) that were compared with healthy cats serving as controls (n = 6). Chest radiographs, BR tests performed non-invasively by barometric whole body plethysmography (BWBP) and bronchoalveolar lavage (BAL) were performed before and after treatment. BR was quantified by calculating the concentration of carbachol inducing bronchoconstriction (C-Penh300%), defined as a 300% increase of baseline Penh, an index of bronchoconstriction obtained by BWBP. BAL fluid was analyzed cytologically and the oxidant marker 8-iso-PGF2α was determined. At test 1, healthy cats and cats with bronchitis were untreated, whereas for test 2 inhalant fluticasone (250 μg once daily) was administrated for 2 consecutive weeks to cats with bronchitis. Control cats remained untreated. Inhaled fluticasone induced a significant increase in C-Penh300% and a significant decrease of BAL fluid total cells, macrophages, neutrophils and 8-iso-PGF2α in cats with bronchitis, whilst untreated control cats did not show significant changes over time. This study shows that a 2-week fluticasone treatment significantly reduced lower airway inflammation in very mild bronchitis. BR could be successfully monitored in cats using BWPB and decreased significantly in response to inhaled fluticasone. 8-Iso-PGF2α in BAL fluid was responsive to treatment and appeared as a sensitive biomarker of lower airway inflammation in cats. [less ▲]

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See detailInhaled nitric oxide for hemodynamic support after postpneumectomy ARDS
Chiche, Jean-Daniel; Canivet, Jean-Luc ULg; Damas, Pierre ULg et al

in Intensive Care Medicine (1995), 21(8), 675-678

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See detailInherent Modulation: a fast chopping method for nulling interferometry
Absil, Olivier ULg

Scientific conference (2002, August 28)

The reduction of the thermal background emission from the local and exo-zodiacal dust clouds is a critical element for the success of ESA's space mission, DARWIN. Internal modulation, a technique using ... [more ▼]

The reduction of the thermal background emission from the local and exo-zodiacal dust clouds is a critical element for the success of ESA's space mission, DARWIN. Internal modulation, a technique using fast signal chopping, isolating the planetary signal from these noise sources, was proposed by Mennesson and Mariotti (Icarus 128, 1997). In this paper, we investigate a modification to the implementation of internal modulation, which provides similar performance with a single detector and a greatly simplified optical layout: the number of beam combiners is reduced by a factor of about two. For example, a Robin Laurance six-telescope interferometer (Karlsson and Mennesson, Proc. SPIE 4006, 2000) can be implemented on five beam combiners instead of twelve. It is demonstrated that inherent modulation can be applied to all existing nulling configurations, including linear arrays. The principle of inherent modulation relies on two nulling interferometers using the same telescopes and beam combination with opposite phase shifts, some of them being different from 0 or pi. During operations, multiplexing between the two interferometers is performed, such that at any time only one interferometer is being used. Since the method lends itself for implementation with four-telescope linear arrays, inherent modulation would also be well suited for the detection of hot Jupiters with a ground-based nulling interferometer on the VLTI. [less ▲]

Detailed reference viewed: 11 (1 ULg)