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See detailFrom the Clinics to the Bench and back to the Clinics: design of a medical treatment for Cervical Intraepithelial Neoplasia (CIN)
Jost, Maud; Frankenne, Francis; Maillard, Catherine ULg et al

Conference (2011, May 20)

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See detailFrom the curriculum framework to its dissemination: the accompaniment of educational practices in care facilities for children under three years
Pirard, Florence ULg

in European Early Childhood Education Research Journal (2011), 19(2), 255-268

Detailed reference viewed: 54 (4 ULg)
See detailfrom the deepest mud mound to the shallowest palaeosoils: correlations and sequence stratigraphy
Da Silva, Anne-Christine ULg; Boulvain, Frédéric ULg

in Abstract book 13th Bathurst meeting of carbonate sedimentologists (2007)

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See detailFrom the design to the clinical application of thromboxane modulators
Dogné, Jean-Michel ULg; Hanson, Julien ULg; de Leval, Xavier et al

in Current Pharmaceutical Design (2006), 12(8), 903-923

Arachidonic acid (AA) metabolites are key mediators involved in the pathogenesis of numerous cardiovascular, pulmonary, inflammatory, and thromboembolic diseases. One of these bioactive metabolites of ... [more ▼]

Arachidonic acid (AA) metabolites are key mediators involved in the pathogenesis of numerous cardiovascular, pulmonary, inflammatory, and thromboembolic diseases. One of these bioactive metabolites of particular importance is thromboxane A(2) (TXA(2)). It is produced by the action of thromboxane synthase on the prostaglandin endoperoxide H-2 (PGH(2)) which results from the enzymatic transformation of AA by the cyclooxygenases. It is a potent inducer of platelet aggregation, vasoconstriction and bronchoconstriction, and has been involved in a series of major pathophysiological conditions. Therefore, TXA(2) receptor antagonists, thromboxane synthase inhibitors and drugs combining both properties have been developed by different laboratories since the early 1980s. Several Compounds have been launched on the market and others are tinder clinical evaluation. In the first part of this review. we will describe the physiological properties of TXA(2), thromboxane synthase and thromboxane receptors. The second part is dedicated to a description of each class of thromboxane modulators with the advantages and disadvantages they offer. In the third part. we aim to describe recent studies performed with the most interesting thromboxane modulators in major pathologies: myocardial infarction and thrombosis, atherosclerosis, diabetes, pulmonary embolism, septic shock.. preeclampsia, and asthma. Each pathology will be systematically reviewed. Finally, in the last part we will highlight the latest perspectives in drug design of thromboxane modulators and in their future therapeutic applications such as cancer, metastasis and angiogenesis. [less ▲]

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See detailFrom the germinal cells to the newborn animal: the transmission of genes and life through the generations
Drion, Pierre ULg; Scenzi, Otto; Ectors Francis et al

(1999, May)

During the last decade, the technology of reproduction progressed considerably leading to a certain availability of in vitro methods for fertilization, maturation of the oocyte and culture system for the ... [more ▼]

During the last decade, the technology of reproduction progressed considerably leading to a certain availability of in vitro methods for fertilization, maturation of the oocyte and culture system for the embryos. The most spectacular manipulations are cloning and transgenesis… This review focuses on the early appearance of the germinal cells precursors and the longstanding destiny of the gametes in mammals. The evident complexity and long-term programmation of events in gametes and early embryo explain the difficulties to succeed in in-vitro methods and the occurrence of unexpected alterations of development, e.g. embryonic or fetal mortalities, large weight newborn syndrome and other dys-regulations in imprinting or DNA transmission. “Studying and teaching the reproductive physiology in mammals, we sometimes imagine that a newborn animal survived two pregnancies: the first one would be a high risk pregnancy that represents the oocyte development and survival inside the follicle with a tetraploïd genome and the zona pellucida & cumulus cells as placenta-like structures. Around the first birth (ovulation), oocytes (individuals) accept in vitro conditions for maturation, fertilization and culture. Afterwards, a second pregnancy will be necessary in the mother or in the recipient uterus; a low risk pregnancy depending on the oocyte competence acquisition and on the conditions or length of exposure in vitro. “ [less ▲]

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See detailFrom the germinal cells to the newborn animal: The transmission of genes and life through the generations
Drion, Pierre ULg; Szenci, Otto; Ectors, Fabien ULg et al

in Acta Veterinaria Hungarica (2003), 51(3), 371-384

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most ... [more ▼]

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most spectacular manipulations are cloning and transgenesis. This review focuses on the early appearance of germinal cell precursors and the long-standing fate of gametes in mammals. The evident complexity and long-term programming of events in gametes and early embryos explain part of the difficulties encountered during the development of in vitro and in vivo methods such as multiple Ovulation and embryo transfer (MOET), oestrus synchronisation, ovulation induction, superovulation, in vitro maturation and fertilisation, cryopreservation, transgenesis, nuclear transfer and cloning) and the occurrence of unexpected alterations of development, e.g. embryonic or fetal mortality, large-weight newborn syndrome and other dysregulations ill imprinting or DNA transmission. [less ▲]

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See detailFrom the Guiding Principles on Internal Displacement to the Nansen Initiative: What the Governance of Environmental Migration Can Learn from the Governance of Internal Displacement
Gemenne, François ULg; Brücker, Pauline

in International Journal of Refugee Law (2015), 27(2), 245-263

Environmental migration is often presented as one of the gravest consequences of environmental disruptions – climate change in particular, and is already a reality in many parts of the world. Yet the ... [more ▼]

Environmental migration is often presented as one of the gravest consequences of environmental disruptions – climate change in particular, and is already a reality in many parts of the world. Yet the protection of these migrants is not adequately addressed in the international normative frameworks on migration. As a result, a growing number of scholars and advocacy groups have sought to create a special convention and/or an ad hoc status for these migrants, while others have contended that such a legal status is not the answer. As a result, the protection of environmental migrants is currently the subject of vigorous debates amongst scholars and policy-makers, and no clear solution is yet in sight. Research however has little considered the debates that surrounded the protection of those displaced within their countries (IDPs) in the 1990s. Both phenomena have sometimes overlapped, especially as environmental displacement is often internal. Yet, the debate on IDPs has had some significant success, in particular, the adoption of the Guiding Principles on Internal Displacement in 1998, and the signature of the Organization for African Unity’s Kampala Convention in 2009. This article argues that important lessons can be drawn from the protection of IDPs in order to inform the current debates on the protection of environmental migrants, as the political contexts and policy challenges associated with both crises of the migration regime are often similar. The article identifies such lessons and assesses the opportunities and caveats of applying a similar approach of soft law to environmental migration – and what would be needed to achieve it. [less ▲]

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See detailFrom the Gymnasium to the Agora: Hermes and his Cult-Epithets
Paul, Stéphanie ULg

Conference (2014, March 29)

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See detailFrom the Herat of the Bayous- Fernest ARCENEAUX - JSP Records- LP sleeve notes & photos
Sacré, Robert ULg

Diverse speeche and writing (1983)

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See detailFrom the Hubble Space Telescope to Juno, unraveling the secrets of Jupiter's UV aurorae
Bonfond, Bertrand ULg

Conference (2015, May 19)

The successive generations of instruments on board the Hubble Space Telescope (HST) have revealed an increasing amount of details concerning the aurorae of Jupiter. Among the most striking results is the ... [more ▼]

The successive generations of instruments on board the Hubble Space Telescope (HST) have revealed an increasing amount of details concerning the aurorae of Jupiter. Among the most striking results is the finding that these aurorae are actually made of a multitude of components arising from a variety of processes, ranging from the local interaction of the Jovian moons with the magnetospheric plasma to solar-wind induced compression of the whole magnetosphere. In this presentation, I will review a few recent results obtained from Hubble Space Telescope observations. First, I will show how the morphology and the dynamics of the Ganymede footprint, i.e. the aurora on Jupiter created by the electromagnetic interaction between Ganymede and Jupiter, allowed us to infer the processes at play. Then, I will present results on the vertical profile of the auroral emissions and what they tell us about the acceleration of the electrons causing the auroral emissions. Furthermore, I will describe some of the short-timescale dynamics of the polar-most emissions, including their quasi-periodic nature. Finally, I will conclude with a short description of the expected outcome of the Juno mission, which will provide its first scientific results in fall 2016. [less ▲]

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See detailFrom the Lyric Subject to the Embouchured Self
Delville, Michel ULg

in Weinstock, Horst (Ed.) Anglistentag Bayreuth (2003)

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See detailFrom the numerisation of the Soil Map of Wallonia to a real information and management tool
Legrain, Xavier ULg; Bah, Boubacar Billo ULg; Veron, Philippe et al

Poster (2007, December 05)

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See detailFrom the ocean to a reef habitat: How do the larvae of coral reef fishes find their way home? A state of art on the latest advances
Barth, P; Berenshtein, I; Besson, M et al

in Vie et Milieu (2015), 65(2), 91-100

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See detailFrom the spirit to the letter of the charters : mind the gap for the future
Houbart, Claudine ULg; Dawans, Stéphane ULg

Conference (2015, June 22)

Since the 1960’s and the foundation of ICOMOS, charters have been considered as a sort of conservation gospel. In this presentation, we would like to question this fact, in the light of the very ... [more ▼]

Since the 1960’s and the foundation of ICOMOS, charters have been considered as a sort of conservation gospel. In this presentation, we would like to question this fact, in the light of the very particular production and reception conditions of the documents. What may be perceived as a mostly provocative approach seems to us a constructive basis for future reflections. When we read and use charters – in this presentation, we will mainly focus on the Venice Charter, the Nara document and the Riga Charter – , we forget too often that they have been written by human beings, sometimes very tired, in a hurry, and even arguing with each other. The study of the archival material related to the writing of the Venice Charter and the Nara document very clearly illustrates that these documents are rather a conceptual “bricolage” than indisputable normative texts as if they had been written by lawyers. In the case of the Venice Charter, the archive as well as the records of Raymond M. Lemaire, Paul Philippot or Gertrud Tripp make clear that the document has been written at the last moment and adopted too rapidly by an assembly too glad to finally have a updated version of the Athens charter. As a consequence, only a few years later, Raymond Lemaire and Piero Gazzola already questioned the validity of the new text in the light of the extension of heritage debates to the city centers. On the other hand, the fact that a French and an English version of the Nara document were written in parallel by Raymond M. Lemaire and Herb Stovel in 1994 has had immediate consequences on the content and the formulation of the text, which logically left both of them unsatisfied with the result. Even so, the Venice charter and the Nara document still have force of law today. Yet, besides the particular circumstances of their writing, we must keep in mind that these texts answered specific questions, closely linked to the context: a critical answer to postwar reconstruction for the first, and apparently opposed visions of authenticity between East and West for the second. As far as the Riga charter is concerned, the influence of the delicate context of the Eastern bloc collapse is evident. For this reason, using such documents today requires at least a critical reading, going back to the spirit beyond the text. Our presentation will illustrate ad absurdum, through recent case studies, how a cynical reading of such documents can lead to interventions dangerously in conflict with this spirit and the fundamental ideals of conservation philosophy. In the era of late capitalism and heritage globalization, are we allowed to forget the conditions and the context in which our doctrinal documents have been written to justify anything and everything and to meet, for example, the “tourist gaze”, the “nouveaux riches” taste or the architect’s egomania? Do architects really want to know what the writers of the Venice charter’s article 9 meant by the “contemporary stamp”? What are the limits of the tolerance towards reconstruction first expressed by the Nara document, and a few years later, the charter of Riga? So many questions that ICOMOS must face if it wants to pursue its guiding mission in a mostly financial world. [less ▲]

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See detailFrom the surface to the Moho and back in a few Myrs: particle's flow path in a sagduction system
François, Camille ULg; Rey, Patrice; Philippot, Pascal et al

in Geological Society of Australia (2014)

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See detailFrom Third Sector to Social Enterprise
Defourny, Jacques ULg

in Borzaga, Carlo; Defourny, Jacques (Eds.) The Emergence of Social Enterprise (2001)

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See detailFrom Third Sector to Social Enterprise: a European Research Trajectory
Defourny, Jacques ULg

in Defourny, Jacques; Hulgard, Lars; Pestoff, Viktor (Eds.) Social Enterprise and the Third Sector (2014)

This first chapter serves as a walking path proposed to the reader who wants to go back to the early works and the seminal contribution of the EMES European Research Network (Borzaga and Defourny, 2001 ... [more ▼]

This first chapter serves as a walking path proposed to the reader who wants to go back to the early works and the seminal contribution of the EMES European Research Network (Borzaga and Defourny, 2001) as well as to revisit a good deal of the works it developed on this basis in the first decade of this century. [less ▲]

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See detailFrom Third Sector to Social Enterprise: Concepts and Methods
Defourny, Jacques ULg

in Comparative Economic and Social Systems = Jingji Shehui Tizhi Bijiao (2009), 7(4), 112-121

Detailed reference viewed: 171 (10 ULg)