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See detailL'humanisation de la mort
Lamy, Maurice ULg

in Annales de l'Anesthésiologie Française (1980), 21(3), 313-314

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See detailHumanisme de conviction ou humanisme instrumental ? Une comparaison des directeurs de prison belges et français
Dubois, Christophe ULg; Mouhanna, Christian

Conference (2014, May 20)

Bien que peu étudiés, les directeurs de prison se situent au centre de l’institution pénitentiaire et font office de véritables interfaces entre les politiques étatiques et les pratiques locales. L’étude ... [more ▼]

Bien que peu étudiés, les directeurs de prison se situent au centre de l’institution pénitentiaire et font office de véritables interfaces entre les politiques étatiques et les pratiques locales. L’étude empiriquement ancrée des pratiques de ce groupe professionnel révèle divers modes de prise en compte de la question humaniste par les acteurs d’un « système pénitentiaire » souvent considéré comme dominé par « l’impératif sécuritaire ». Quant à l’analyse de leurs discours, elle permet de rendre compte du positionnement particulier de nombreux directeurs de prison vis-à-vis de leur administration (collectivement, via les syndicats et associations de directeurs, ou individuellement, via les médias et autres publications) et vis-à-vis de l’institution judiciaire (juges d’instruction, tribunaux de l’application des peines, Conseil d’Etat). Notre contribution repose sur deux enquêtes réalisées au cours des trois dernières années auprès de directeurs belges (n = 32) et français (n = 20). Les degrés de hiérarchisation et de judiciarisation des contextes de travail des directeurs varient au sein des ces deux pays et déterminent, en partie, les modalités d’interaction quotidienne des directeurs en détention (avec les détenus, les services psychosociaux, les surveillants, etc.) et autour de la détention (avec l’administration centrale, le TAP, la justice, les associations diverses, etc.). Il s’agira de saisir et de rendre visible la dimension humaniste du travail des directeurs, tant au niveau de leurs pratiques (cultures professionnelle et organisationnelle) que de leurs discours professionnels (logiques de justification). En effet, ce qu’ils qualifient, par exemple, d’ « empathie », d’ « intensité des relations », de « recherche du sens de leur travail » et de « sens de la peine », semblent orienter leur travail dans des marges qu’il conviendra de préciser. [less ▲]

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See detailL'humanisme face au terrorisme
Seron, Vincent ULg

in Cahiers de défense sociale (2000)

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See detailHumanisme pratique et antihumanisme théorique
Delruelle, Edouard ULg

Article for general public (2012)

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See detailHumanisme, classicisme et tradition dans la vie et l’œuvre d’Arsène Soreil
Delhalle, Nancy ULg

in La Vie Wallonne (1989), 405-406

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See detailL'humanisme, inutile et incertain? Une critique des droits de l'homme
Delruelle, Edouard ULg

Book published by Labor (1999)

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See detailHumanitarian aid and health services in Eastern Kivu, Zaïre: collaboration or competition
Goyens, Philippe; Porignon, Denis ULg; Mugisho Soron'Gane, Etienne et al

in Journal of Refugee Studies (1996), 9(3), 268-280

The population of eastern Kivu, like that of Rwanda, has been surviving in critical conditions for many years. The Rwandan refugees of 1994 fled into an area with its own serious problems. The Zairean ... [more ▼]

The population of eastern Kivu, like that of Rwanda, has been surviving in critical conditions for many years. The Rwandan refugees of 1994 fled into an area with its own serious problems. The Zairean health services in the health districts of Rutshuru, Kirotshe and Masisi, in spite of the political and socioeconomic disintegration of the country, were still functioning, and the local hospitals and health centres, although overwhelmed, contributed to a large extent to the disaster response. Prominent among the major problems facing the local health services were their limited adaptability, the inadequate coordination and collaboration offered to them by the humanitarian aid agencies, and the discrimination between the direct and secondary victims of the emergency. The public health consequences of the Rwandan refugee crisis for the Zairean population constitute an integral part of the disaster. [less ▲]

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See detailLes humanités chrétiennes
Kurth, Godefroid ULg

Speech/Talk (1901)

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See detailLes humanités de demain
Kurth, Godefroid ULg

in Bulletin de la Classe des Lettres et des Sciences Morales et Politiques (1902)

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See detailHumanities 2.0. Document, interpretation and intersubjectivity in the digital age
Bénel, Aurélien; Lejeune, Christophe ULg

in International Journal of Web-Based Communities (2009), 5(4), 562-576

With their focus on documents, interpretation and intersubjectivity, Web 2.0 technologies have surprising analogies with philosophical hermeneutics, the theory of texts interpretation. Philosophical ... [more ▼]

With their focus on documents, interpretation and intersubjectivity, Web 2.0 technologies have surprising analogies with philosophical hermeneutics, the theory of texts interpretation. Philosophical hermeneutics was generalised from biblical hermeneutics by Dilthey in the 19th century, and chosen as an alternative to positivism as a foundation for the epistemology and methodology of the humanities and social sciences. This article explores how Web 2.0 technologies might better meet the needs of social and human sciences than traditional information technologies that are historically bound with logical positivism. Illustrations are provided from archaeology and sociology, two social and human sciences which were early adopters of punched cards and computers. [less ▲]

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See detailHumanized mice as a useful model to study HIV-1 induced immune activation, its mechanisms and potential therapeutic approaches
Singh, Maneesh; Singh, Pratibha; VAIRA, Dolorès ULg et al

in Retrovirology (2011, October 03), 8

Recent understanding of HIV-1 pathogenesis mechanism has changed our views about possible mechanisms of CD4T-cell depletion during infection. Apart from HIV-1-mediated killing a more comprehensive ... [more ▼]

Recent understanding of HIV-1 pathogenesis mechanism has changed our views about possible mechanisms of CD4T-cell depletion during infection. Apart from HIV-1-mediated killing a more comprehensive explanation has appeared that includes T cell exhaustion and chronic immune activation as a central feature in HIV-1 pathogenesis. While highly active antiretroviral therapy (HAART) markedly reduces viral load, T cell activation levels and soluble markers of inflammation remain abnormally high. Markers of chronic activation, such as CD38, PD-1 or HLA-DR on T cells, appear to be better predictors for clinical progression during HIV infection than HIV RNA levels and CD4Tcell counts alone. Therefore, a better understanding of HIV-índuced immune activation and the design of new immunomodulatory approches in combination with HAART are needed. We have generated an efficient model of human stem cells (HSCs) engraftment in NOD/LtsZ-scidlL-2Rnull (NSG) mice that supports chronic HIV infection with high plasma viral loads. HIV-1 infection in these humanized mice is characterized by widespread immune activation with increased expression of PD-1, HLA-DR, CD38, CD69, CD25 and other immune activation markers. These humanized mice provide an effective in vivo system for the assessing novel approaches for their potential in suppressing chronic immune activation during HIV-1 infection, in absence of interference of antiretroviral therapy. In this study, we evaluated in vivo the benefits of two novel approaches aimed at reducing HIV-induced immune activation. Minocycline is an antibiotic of the tetracycline family with anti-inflammatory and immunomodulatory properties affecting CD4 T cells activation by a mechanism involving the inhibition of the NF-AT1 transcription factor activity. We hypothesized that this antibiotic could suppress the HIV-1-induced chronic immune activation and thus, limit the HIV pathogenesis when combined to HAART. Therefore, we treated HIV-1 (JRCSF) infected-humanized NSG mice with minocycline (100mg/kg/day) for 60 days. We next evaluated the expression, by flow cytometry, of several T cells activation markers together with CD4+T cells counts. Our data suggest that minocycline is effective in suppressing HIV-1 induced immune activation in peripheral blood and lymphoid organs (spleen, lymph nodes and bone marrow). Levels of cellular immune activation markers such as PD-1, HLA-DR, CD38, CD69, CD25, CD28 and CTLA-4 were significantly lower in minocycline treated group. These immunological benefits of minocycline were correlated with higher CD4+T cell counts in the treated group. The immune activation which is associated with retroviral infection is also associated with increased levels of intracytoplasmic cyclic AMP which could act as a positive feedback loop in the infection since several reports have suggested that cAMP and downstream signaling pathways play an important role in the permissivity of susceptible cells to HIV infection and replication. We have used a peptide which prevents the binding of the catalytic subunit of PKA type I to its anchoring protein and therefore blocks most effects of cyclic AMP within lymphocytes and monocytes (RIAD peptide). Mice were treated with 3.5 mg/kg of RIAD peptide weekly. Treatment of humanized mice with RIAD peptide limited viral replication after high dose of HIV intraperitoneal challenge and reduced the intracytoplasmic levels of cyclic AMP. Further experiments are needed to better appreciate the therapeutic potential of these novel therapies in the suppression of HIV-induced chronic immune activation. [less ▲]

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See detailHumanizing the Clinical Gaze: Movies and the Empathic Understanding of Psychosis
Raballo, A.; Laroi, Frank ULg; Bell, V.

in Family Medicine (2009), 41(6), 387-388

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See detailHumidity 3D field comparisons between GNSS tomography, IASI satellite observations and ALARO model
Brenot, Hugues; Champollion, Cedric; Deckmyn, Alex et al

in Geophysical Research Abstracts (2012, April), 14

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See detailHumn Bocavirus, a newly discovered Parvovirus of the respiratory tract
RICOUR, Céline ULg; GOUBAU, P

in Acta Clinica Belgica (2008), 64(5), 329-332

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See detailHumnétriai… Un rite mis en images chez Philostrate
Pironti, Gabriella; Pirenne-Delforge, Vinciane ULg

in Calame, Claude; Ellinger, Pierre (Eds.) Du récit au rituel par la forme esthétique : pragmatique cultuelle des formes discursives et des images en Grèce ancienne (in press)

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See detailHumoral and Cell-Mediated Immune Responses of Beef and Dairy Cattle Experimentally Infested with Psoroptes Ovis
Lonneux, J. F.; Nguyen, T. Q.; Hollanders, W. et al

in American Journal of Veterinary Research (1998), 59(5), 583-7

OBJECTIVE: To compare cellular and humoral immune responses of beef (Belgian White and Blue [BWB]) and dairy (Friesian-Holstein [FH]) cattle to Psoroptes ovis infestation and to determine whether P ovis ... [more ▼]

OBJECTIVE: To compare cellular and humoral immune responses of beef (Belgian White and Blue [BWB]) and dairy (Friesian-Holstein [FH]) cattle to Psoroptes ovis infestation and to determine whether P ovis infestation impaired immune responses to infectious bovine rhinotracheitis virus (IBR) vaccine or an immunogenic protein (keyhole-limpet hemocyanin [KLH]). ANIMALS: 19 BWB and 6 FH 1-year-old calves. PROCEDURE: 2 trials were performed. In each trial, 7 (trial 1) or 6 (trial 2) BWB calves and 3 FH calves were experimentally infested with P ovis and 3 BWB calves were maintained as uninfested controls. Animals were inoculated with KLH and IBR virus vaccine twice; 3 BWB calves in each trial were treated with ivermectin. Serum antibody responses to KLH, IBR virus, and P ovis were measured by use of ELISA. A lymphocyte transformation assay was used to determine nonspecific responses to 3 mitogens and specific lymphocyte reactivity to P ovis antigen. RESULTS: In each trial, 3 BWB and 3 FH calves developed clinical signs of psoroptic mange and mites could be recovered. Infested and control animals developed similar antibody titers to KLH and IBR virus. Antibodies to P ovis were detected early in some infested calves, and this was correlated with a marked cell-mediated immune response. Lymphocyte responsiveness to the 3 mitogens was not significantly different among groups. CONCLUSIONS: In these calves, infestation with P ovis induced a marked humoral and cell-mediated immune response. Immunosuppression was not evident. [less ▲]

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See detailHumoral and cellular immune response to a crude exo-antigen and purified keratinase of Microsporum canis in experimentally infected guinea pigs.
Mignon, Bernard ULg; Leclipteux, T.; Focant, Charles ULg et al

in Medical Mycology (1999), 37(2), 123-129

In order to understand better the host-parasite relationship and to compare with previous observations in Microsporum canis naturally infected cats, the humoral and cellular immune responses to both a ... [more ▼]

In order to understand better the host-parasite relationship and to compare with previous observations in Microsporum canis naturally infected cats, the humoral and cellular immune responses to both a crude exo-antigen and a 31.5 kDa purified keratinase were evaluated in 12 M. canis experimentally infected guinea pigs. Humoral and cellular responses were assessed by ELISA from days 0 to 56 postinfection (PI) and by measurement of delayed-type hypersensitivity (DTH) responses on days 14 and 57 PI, respectively. Additionally, immunohistochemical staining was performed and demonstrated that the keratinase was produced in infected guinea pig skin, as previously reported in cats. Despite a marked interindividual variation, all the guinea pigs produced specific IgG to the crude exo-antigen from day 21 PI onwards, but no anti-keratinase IgG was detected. Strongly positive DTH responses to the exo-antigen were observed on both dates, whereas the keratinase elicited no and weak DTH on days 14 and 57 PI, respectively. These results are in agreement with those previously described for naturally infected cats, and indicate that the 31.5 kDa keratinase is not a major antigen in M. canis infection. [less ▲]

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See detailHumoral and cellular immune response to a Microsporum canis recombinant keratinolytic metalloprotease (r-MEP3) in experimentally infected guinea pigs
Brouta, Frédéric; Descamps, Frédéric; Vermout, Sandy et al

in Medical Mycology (2003), 41(6), 495-501

In order to better understand the host-fungus relationship in Microsporum canis dermatophytosis and to identify major fungal antigens, the immune response to a crude exoantigen preparation and to a ... [more ▼]

In order to better understand the host-fungus relationship in Microsporum canis dermatophytosis and to identify major fungal antigens, the immune response to a crude exoantigen preparation and to a purified recombinant keratinolytic metalloprotease (r-MEP3) was evaluated in guinea pigs experimentally infected with M. canis. Humoral and cellular immune responses were assessed from day 0 to day 57 post-infection (PI), the former by enzyme-linked immunosorbent assay (ELISA) and the latter via a lymphocyte proliferation assay. Infected guinea pigs developed humoral and cellular responses to both M. canis exoantigen and r-MEP3, while no specific immune response to these antigens was observed in control animals. This is the first report on the development of both humoral and cell-mediated immune responses to a purified keratinase in M. canis dermatophytosis. [less ▲]

Detailed reference viewed: 51 (5 ULg)