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See detailInfluence of Estrogen Replacement Therapy on Endogenous Calcitonin Production Rates
Reginster, Jean-Yves ULg; Deroisy, Rita ULg; Fontaine, M. A. et al

in Gynecological Endocrinology : The Official Journal of the International Society of Gynecological Endocrinology (1992), 6(1), 65-71

Calcitonin is now a well-accepted therapy for inhibition of bone loss, both in the first years of menopause and in established osteoporosis. However, its exact role in the pathogenesis of that disease as ... [more ▼]

Calcitonin is now a well-accepted therapy for inhibition of bone loss, both in the first years of menopause and in established osteoporosis. However, its exact role in the pathogenesis of that disease as well as the interactions between calcitonin production and estrogen metabolism remain unsolved. In order to clarify the influence of estrogen replacement therapy (ERT) on calcitonin secretory capacity, we measured whole plasma immunoreactive calcitonin basal levels, metabolic clearance rates and production rates in a group of postmenopausal women, before and after a daily intake for 28 days of 0.625 mg/day of conjugated equine estrogens, and again 4 weeks after the withdrawal of that estrogen replacement therapy. No significant changes appeared in immunoreactive calcitonin or immunoreactive calcitonin metabolic clearance rate but the production rate significantly increased over the 28 days (mean +/- SEM, from 21.3 +/- 5.1 pg/ml to 25.2 +/- 5.9 pg/ml, p less than 0.05), and then decreased 4 weeks after therapy was withdrawn to the initial level (17.9 +/- 3.6 pg/ml). We concluded that estrogen replacement therapy significantly increases calcitonin secretory capacity. This confirms the interactions between calcitonin production and estrogen metabolism, and may provide an explanation concerning the mode of action of estrogen replacement therapy in prevention of postmenopausal bone loss. [less ▲]

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See detailInfluence of estrogens on oxytocinergic function in the human: implications in aging.
Legros, Jean-Jacques ULg; Geenen, Vincent ULg; Franchimont, Paul

in Rolland, R. (Ed.) Neuroendocrinology of reproduction (1987)

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See detailInfluence of evaporation and seepage on the convergence of a ventilated cavity
Gerard, Pierre ULg; Charlier, Robert ULg; Chambon, René et al

in Water Resources Research (2008), 44

In the design of nuclear waste disposals, an important topic concerns the development of an excavated damage zone, where permeability increases. A correct numerical prediction of the coupled processes ... [more ▼]

In the design of nuclear waste disposals, an important topic concerns the development of an excavated damage zone, where permeability increases. A correct numerical prediction of the coupled processes occurring during excavation is therefore needed. In this paper, a nonclassical hydraulic boundary condition is described. It mixes two modes of water exchanges in partial saturation: seepage and evaporation flows. Seepage flow avoids unphysical water inflow into the rock mass, which might be obtained with usual boundary condition in dilatant geomaterial. Evaporation flows enable the thermodynamical equilibrium between air relative humidity in the cavity and in the rock mass. The numerical modeling of a cavity excavation in dilatant geomaterial is carried out. The results show the influence of the hydraulic boundary condition on the convergence of the cavity. Depending on the value of the transfer coefficient, the proposed numerical model can recover the results obtained with an imposed atmospheric pressure or suction at the cavity wall. The determination of the mass transfer coefficient is thus needed and can be achieved through drying experiments or can be estimated thanks to in situ measurements. [less ▲]

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See detailInfluence of excessive carbides upon strength of hot rolled rolls of steel similar to high speed grade
Lecomte-Beckers, Jacqueline ULg; Herman, M.; Breyer, J. P.

in Stal' (2006), 9

This paper will illustrate the choice of the alloying elements and their content in the current grade. By using sophisticated laboratory examination techniques such as differential thermal analysis ... [more ▼]

This paper will illustrate the choice of the alloying elements and their content in the current grade. By using sophisticated laboratory examination techniques such as differential thermal analysis, scanning electron microscopy and image analysis, the metallurgical parameters of Aurora grade will be described and compared to those of the Kosmos grade. An attempt will also be made to connect all our laboratory results to the good behaviour of the alloy in operation in the early stands of Hot Strip Mills. [less ▲]

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See detailInfluence of exogenous oestrogen or (anti-) androgen administration on soluble transferrin receptor in human plasma.
T'Sjoen, Guy; Beguin, Yves ULg; Feyen, Els et al

in Journal of Endocrinology (2005), 186(1), 61-7

The objective of this investigation was to study the effects of sex steroids on levels of haemoglobin (Hb) and haematocrit (Hct) and to analyse whether these effects can be related to levels of the ... [more ▼]

The objective of this investigation was to study the effects of sex steroids on levels of haemoglobin (Hb) and haematocrit (Hct) and to analyse whether these effects can be related to levels of the soluble transferrin receptor (sTfR), a marker of erythropoietic activity. Nineteen male-to-female transsexuals were randomly assigned to either oral ethinyl oestradiol (EE) (n=12) or transdermal 17beta-oestradiol (E2) (n=7); both treatments included the anti-androgen cyproterone acetate (CA). Six male-to-female transsexuals were treated with CA only. Fifteen female-to-male transsexuals were treated with i.m. testosterone esters. The Hct, and levels of Hb, IGF-I, GH and sTfR were measured before and after 4 months of hormone administration. Androgen administration significantly increased the sTfR concentration by 31.5% (P=0.008) and increased levels of Hct, Hb and IGF-I. Both regimens of CA with oral EE and transdermal E2 reduced plasma testosterone similarly to castrate values and decreased Hb and Hct. The CA+oral EE combination induced a decrease in sTfR of 19.0% (P=0.002) which was not the case with CA+transdermal E2 (P=0.27). This cannot be explained by the profound decline in plasma testosterone which was similar with both regimens, but this difference could be related to the different effects of the two regimens on plasma IGF-I. This assumption is supported by the positive correlation that was found to exist between plasma sTfR and IGF-I after the interventions (P<0.05). [less ▲]

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See detailInfluence of Exozodiacal Dust Clouds on Mid-IR Earth-like Planet Detection
Defrère, D.; Absil, Olivier ULg; den Hartog, R. et al

in Coudé du Foresto, Vincent; Gelino, Dawn; Ribas, Ignasi (Eds.) Pathways Towards Habitable Planets (2010, October 01)

The characterization of Earth-like extrasolar planets in the mid-infrared is a significant observational challenge that could be tackled by future space-based interferometers. A large effort has been ... [more ▼]

The characterization of Earth-like extrasolar planets in the mid-infrared is a significant observational challenge that could be tackled by future space-based interferometers. A large effort has been carried out the past two decades to define a design that provides the necessary scientific performance while minimizing cost and technical risks. These efforts have resulted in a consensus on a single mission architecture consisting of a non-coplanar X-array (the so-called Emma configuration), using four collector spacecraft and a single beam combiner spacecraft. The ability to study distant planets with an X-array interferometer will however depend on exozodiacal dust clouds, the counterparts of the solar zodiacal disk. In this paper, we briefly discuss the impact of exozodiacal clouds on the performance of an Emma X-array interferometer dedicated to Earth-like planet characterization. [less ▲]

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See detailInfluence of experimental parameters on properties and microstructure of the steel X210CrW12 in the semi-solid state
Fraipont, Céline; Puettgen, Wolfgang; Bleck, Wolfgang et al

in Solid State Phenomena (2006), 116-117

This paper deals with the examination of the steel grade X210CrW12 and its suitability for Thixoforming. In the semi-solid state, the microstructure of this steel consists of a homogeneous distribution of ... [more ▼]

This paper deals with the examination of the steel grade X210CrW12 and its suitability for Thixoforming. In the semi-solid state, the microstructure of this steel consists of a homogeneous distribution of globular particles surrounded by liquid. Additionally, carbides are stabile up to fraction liquid contents of approximately 40%. After quenching, this steel reveals a globular austenitic microstructure with eutectic (former liquid phase) at the grain boundaries. Compression tests permit to determine the influence of different process parameters on the properties and the material behaviour in the semi-solid state. Their influence on the microstructure was investigated but not yet highlighted. Further investigations on this steel allow a fine-tuning to establish optimal process windows of the different thixoforming- and rheoforming-routes. [less ▲]

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See detailInfluence Of Extrusion On Ruminal And Intestinal Disappearance In Sacco Of Pea (Pisum-Sativum) Proteins And Starch
Walhain, Philippe; Foucart, Michel; Thewis, André ULg

in Animal Feed Science & Technology (1992), 38(1), 43-55

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See detailThe influence of facial emotion displays gender, and ethnicity on judgments of dominance and affiliation
Hess, U; Blairy, Sylvie ULg; Kleck, R

in Journal of Nonverbal Behavior (2000), 24(4), 265-283

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See detailInfluence of fasting on serum IGFBPs levels in broiler breeders.
Bruggeman, Veerle; Renaville, Robert ULg; Vanmontfort, D. et al

in Hormone binding proteins: physiology and clinical implications symposium (1995)

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See detailINFLUENCE OF FATIGUE ON THE STRIDE CHARACTERISTICS DURING AN INTENSE ENDURANCE RUNTEST
Jidovtseff, Boris ULg; Rodriguez de la Cruz, Carlos ULg; Croisier, Jean-Louis ULg et al

in Abstract book of 17th ECSS Congress (2012, July)

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See detailInfluence of fermentable carbohydrates or protein on large intestinal and urinary metabolomic profiles in piglets
Pieper, R; Neumann, K; Kröger, S et al

in Journal of Animal Science (2012), 90(Supplement 4), 34-36

It was recently shown that variations in the ratio of dietary fermentable carbohydrates (fCHO) and fermentable protein (fCP) differentially affect large intestinal microbial ecology and the mucosal ... [more ▼]

It was recently shown that variations in the ratio of dietary fermentable carbohydrates (fCHO) and fermentable protein (fCP) differentially affect large intestinal microbial ecology and the mucosal response. Here we investigated the use of mass spectrometry to profile changes in metabolite composition in colon and urine associated with variation in dietary fCHO and fCP composition and mucosal physiology. Thirty-two weaned pigletswere fed 4 diets in a 2 × 2 factorial design with low fCP and low fCHO, low fCP and high fCHO, high fCP and low fCHO, and high fCP and high fCHO. After 21 to 23 d, all pigs were euthanized and colon digesta and urine metabolite profiles were obtained by mass spectrometry. Analysis of mass spectra by partial least squares approach indicated a clustering of both colonic and urinary profiles for each pig by feeding group. Metabolite identification and annotation using the Kyoto Encyclopedia of Genes and Genomes (KEGG) metabolic pathways revealed increased abundance of metabolites associated with arachidonic acid metabolism in colon of pigs fed a high concentration of fCP irrespective of dietary fCHO. Urinary metabolites did not show as clear patterns. Mass spectrometry can effectively differentiate metabolite profiles in colon contents and urine associated with changes in dietary composition. Whether metabolite profiling is an effective tool to identify specific metabolites (biomarkers) or metabolite profiles associated with gut function and integrity needs further elucidation. [less ▲]

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See detailThe Influence of Fetal and Postnatal Growth on Heart Rate Variability in Young Infants
Massin, M. M.; Withofs, Nadia ULg; Maeyns, K. et al

in Cardiology (2001), 95(2), 80-3

Heart rate variability (HRV), a measure of cardiac autonomic control, was analyzed in infants to assess the hypothesis that early undernutrition may induce autonomic dysfunction that could play a role in ... [more ▼]

Heart rate variability (HRV), a measure of cardiac autonomic control, was analyzed in infants to assess the hypothesis that early undernutrition may induce autonomic dysfunction that could play a role in the programming of later cardiovascular disease. HRV data were collected during a night session in 546 healthy infants at 5-12 weeks of adjusted age, and statistical associations with fetal and postnatal growth indices were established. A significant positive correlation between birth weight, the ratio of neonatal weight to head circumference and postnatal weight gain, and HRV indices mostly influenced by sympathetic activity was demonstrated in 11- and 12-week-old infants. A slight correlation (p > 0.05) was also found in younger infants. These data suggest the influence of fetal and postnatal growth on the programming of the autonomic nervous system beyond the neonatal period. This influence may be one of the important mechanisms that link impaired growth in fetal and infant life to high blood pressure and other cardiovascular disease during childhood and adulthood (the Barker hypothesis). [less ▲]

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See detailInfluence of Fiber Distribution and Grain Size on the Mechanical Behavior of Friction Stir Processed Mg-C Composites
Mertens, Anne ULg; Montrieux, Henri-Michel ULg; Lecomte-Beckers, Jacqueline ULg et al

Conference (2012, November 12)

Short C fibers-Mg matrix composites have been produced by friction stir processing sandwiches made of a layer of C fabric stacked between two sheets of either the ductile Mg alloy AZ31B, or of the less ... [more ▼]

Short C fibers-Mg matrix composites have been produced by friction stir processing sandwiches made of a layer of C fabric stacked between two sheets of either the ductile Mg alloy AZ31B, or of the less ductile alloy AZ91D, that is capable of age hardening. It has been shown that the choice of the optimal experimental parameters for the production of sound composites was strongly dependent on the nature of the matrix. 3D X-ray tomography reveals that the fibers orient along the onion rings and that they are more or less fragmented depending on the local shear stress during the process. The fiber volume fraction is increased when the nugget volume decreases in particular for the AZ91D base material and for a high advancing speed for the AZ31B base material. The fiber volume fraction influences directly the grain size, the hardness and the tensile properties of the composites. [less ▲]

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See detailInfluence of firing time and framework thickness on veneered Y-TZP discs curvature.
Jakubowicz-Kohen, Boris D.; Sadoun, Michael J.; Douillard, Thierry et al

in Dental materials : official publication of the Academy of Dental Materials (2013)

OBJECTIVES: The objective of the present work was to study the curvature of very thinly, veneered Y-TZP discs of different framework thicknesses submitted to different firing times. METHODS: Fifteen 20-mm ... [more ▼]

OBJECTIVES: The objective of the present work was to study the curvature of very thinly, veneered Y-TZP discs of different framework thicknesses submitted to different firing times. METHODS: Fifteen 20-mm-wide Y-TZP discs were produced in three different thicknesses: 0.75, 1, 1.5mm. One disc from each group was left unveneered while the others were layered with a 0.1mm veneering ceramic layer. All discs underwent five firing cycles for a total cumulative firing time of 30min, 1, 2, 5 and 10h at 900 degrees C. The curvature profile was measured using a profilometer after the veneering process and after each firing cycle respectively. A fitted curve was then used to estimate the, curvature radius. The coefficient of thermal expansion (CTE) measurements were taken on veneering, ceramic and Y-TZP beam samples that underwent the same firing schedule. Those data were used to calculate the curvature generated by CTE variations over firing time. RESULTS: All bilayered samples exhibited a curvature that increased over firing time inversely to framework thickness. However non-veneered samples did not exhibit any curvature modification. SIGNIFICANCE: The results of the present study reveal that even a very thin veneer layer (0.1mm) can induce a significant curvature of Y-TZP discs. The dilatometric results showed that Tg and CTE, variations are not sufficient to explain this curvature. A chemical-induced zirconia volume, augmentation located at the framework sub-surface near the interface could explain the sample, curvature and its increase with firing time. [less ▲]

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See detailThe influence of foam morphology of multi-walled carbon nanotubes/poly(methyl methacrylate) nanocomposites on electrical conductivity
Tran, Minh Phuong ULg; Detrembleur, Christophe ULg; Alexandre, Michaël ULg et al

in Polymer (2013), 54(13), 3261-3270

Polymer/multi-walled carbon nanotubes (PMMA/MWNTs) nanocomposites foams are widely investigated during the last decade thanks to their potential applications as electromagnetic interferences shielding ... [more ▼]

Polymer/multi-walled carbon nanotubes (PMMA/MWNTs) nanocomposites foams are widely investigated during the last decade thanks to their potential applications as electromagnetic interferences shielding (EMI) materials. Electrical conductivity of the nanocomposite is a key parameter for these applications. In the frame of this work, we aim at establishing relationships between the foams morphology and their electrical conductivity. We therefore first design nanocomposite foams of various morphologies using supercritical carbon dioxide (scCO2) as physical foaming agent. The nanocomposites based on poly(methyl methacrylate) (PMMA) and different carbon nanotubes loadings are prepared by melt-mixing and foamed by scCO2 in various conditions of pressure, temperature and soaking time. The influence of these foaming conditions on the morphology of the foams (volume expansion, pore size, cell density, cell-wall thickness) is discussed. After measuring the electrical conductivity of the foams, we establish structure/properties relationships that are essential for further optimizations of the materials for the targeted application. [less ▲]

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See detailThe influence of follicular dendritic cells on B-cell proliferation depends on the activation of B cells and the mitogen used.
Bosseloir, A.; Bouzahzah, F.; Defrance, T. H. et al

in Scandinavian Journal of Immunology (1996), 43(1), 23-30

Follicular dendritic cells (FDC) are unique non-lymphoid cells found only in lymph follicles. They play a part in the survival, proliferation and differentiation of B cells. To analyse the influence of ... [more ▼]

Follicular dendritic cells (FDC) are unique non-lymphoid cells found only in lymph follicles. They play a part in the survival, proliferation and differentiation of B cells. To analyse the influence of FDC on B-lymphocyte proliferation, we isolated them from human tonsils on albumin gradients and treated them with mitomycin C to prevent the multiplication of lymphoid cells harboured in their cytoplasmic evaginations. FDC cultured for 12-16 h remained attached to the substrate; non-adherent cells were carefully eliminated by washing. Purified B cells cultured alone or with contaminant-cleared FDC were maintained for 2 days in the presence or absence of various stimulants, after which tritiated thymidine uptake by these cells was measured. In the absence of activators, FDC did not induce B-cell multiplication. B cells cultured in the presence of FDC exhibited increased 3H-TdR uptake when activated with anti-CD40 MoAb, anti-immunoglobulin MoAb or transferrin, but not when stimulated with Staphylococcus aureus strain Cowan I (SAC) at a given concentration. In the latter case, B-cell proliferation clearly decreased. In control cocultures where mitomycin-C-treated non-adherent cells were used instead of FDC in the presence of the different stimulants, no increase in B-cell proliferation was observed. The results suggest that, inside the germinal centres, FDC modulation of B-cell proliferation depends on the activation state of the B cells and on the stimulant encountered. [less ▲]

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See detailInfluence of food resources on the ranging pattern of Northern pig-tailed macaques (Macaca leonina)
Albert, Aurelie; Huynen, Marie-Claude ULg; Savini, Tommaso et al

in International Journal of Primatology (2013)

Food availability may influence primates’ home range size and use. Understanding this relationship may facilitate the design of conservation strategies. We aimed to determine how fruit availability ... [more ▼]

Food availability may influence primates’ home range size and use. Understanding this relationship may facilitate the design of conservation strategies. We aimed to determine how fruit availability influences the ranging patterns of a group of northern pig-tailed macaques (Macaca leonina) living around the visitor center of Khao Yai National Park, Thailand. We predicted that macaques would increase their range during low fruit abundance periods to gather high-quality food and that they would go where there are more fruits or more fruits of particular species. We also predicted that human food, linked to human pre sence, would attract the macaques. We followed the macaques and recorded their diet and movements within their home range. We superimposed a grid on kernels defining the monthly home range surface to compare spatially macaques’ travel and the availability of fruits measured on botanical transects. Our results showed that the macaques increased their monthly home range in March, probably to obtain newly available fruits. During high fruit abundance seasons, they spent more time near particular fruit species. In August and September, although fruits became rare again, macaques kept their home range large, perhaps to find enough fruits as supplies dwindled. Finally, from October to February, they decreased their monthly home range size while consuming human food, a highquality item. In conclusion, the macaques used several ranging strategies according to fruit availability. however, we think that, without human food, macaques would tend to increase their range during low fruit abundance periods, as predicted. [less ▲]

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