Maladie de Horton et atteintes artérielles extra-temporales: utilité de la tomographie par émission de positons au 18FDG. A propos de trois observations et d’une revue de la littérature.

in Revue de Médecine Interne (2002), 23(7), 584-591

Increased glucose metabolism detected by (18)FDG PET imaging in unsuspected extra-temporal vessels locations of Horton's disease. Clinical observations and review of literature. Purpose. - We report three ... [more ▼]

Increased glucose metabolism detected by (18)FDG PET imaging in unsuspected extra-temporal vessels locations of Horton's disease. Clinical observations and review of literature. Purpose. - We report three cases of Horton's disease, in which F18-Fluorine-2-Deoxy-D-Glucose ((18)FDG) positron emission tomography (PET) demonstrated a clinically unsuspected extra-cranial vessels hypermetabolism. Methods. - Fully corrected whole-body PET was performed in three patients (two women, one man) for exploring a marked inflammatory syndrome. Scanning was acquired 60 min after i.v. injection of 222 MBq of (18)FDG in average. Results. - In two patients with histologically proven Horton's disease, PET alone showed increased glucose metabolism involving the carotid and sub-clavian arteries as well as the ascending aorta, aortic arch, thoracic and abdominal aorta, and the iliac and femoral arteries. In the third patient, by detecting cervical, thoracic and abdominal vessel hypermetabolism, PET non-invasively contributed to the diagnosis of giant cell arteritis. All patients had complete clinical and biological response to corticoids. PET controls performed 3- to 6-months post-treatment, confirmed the disappearance of the metabolic stigma. Conclusion. - (18)FDG PET may show an increased glucose metabolism in asymptomatic extra-cranial vessels locations of Horton's arteritis. If these observations are confirmed on controlled trials, PET could be particularly useful for non-invasive diagnosing, staging and monitoring atypical clinical forms of Horton's disease. The metabolic imaging could also contribute to a better understanding of the pathogenesis of GCA. (C) 2002 Editions scientifiques et medicales Elsevier SAS. [less ▲]

Maladie de Kaposi chez une patiente souffrant d'une immunodéficience acquise VIH négative

in Presse Médicale (Paris, France : 1983) (1994), 23(38), 1760-1761

A 79-year-old woman of Mediterranean ascent suffered from corticosteroid-dependent chronic obstructive lung disease, hypogammaglobulinemia (IgG 1 and 2), decreased CD16 natural killer cell function and ... [more ▼]

A 79-year-old woman of Mediterranean ascent suffered from corticosteroid-dependent chronic obstructive lung disease, hypogammaglobulinemia (IgG 1 and 2), decreased CD16 natural killer cell function and non-HIV related CD4 and CD8 lymphopenia. Such immunodeficiency could be either a variant of common variable immunodeficiency or an early stage of the idiopathic CD4 + T lymphocytopenia syndrome. She developed bilateral lesions of Kaposi's sarcoma on the lower extremities resembling the classic European type of the disease. The tumors contained both CD34 + and Factor XIIIa + cells. The HLA-DR5 haplotype was not found. Weekly low intravenous dosages of vinblastine improved the lesions but the patient died from pontic infarction. [less ▲]

La maladie de Lyme : une nouvelle maladie?

in Annales de Médecine Vétérinaire (1994), 138

La maladie de Mortellaro: un fléau insidieux dans les élevages bovins

Article for general public (2009)

Maladie de Zellweger et adrenoleukodystrophie néonatale: une même maladie ou deux affections distinctes?

in Progress en neurologie pédiatrique (1985)

La maladie du hêtre : catastrophe écologique ou accident de la nature.

in Parcs & Réserves (2000), 55(3-4), 49

La "maladie du Hêtre" en Ardenne belge

in Gauquelin, Xavier (Ed.) Guide de gestion des Forêts en crise sanitaire (2010)

Les crises sanitaires font partie des aléas auxquels les forêts gérées sont parfois confrontées. Elles sont susceptibles de se multiplier au cours des décennies à venir, notamment du fait des conséquences ... [more ▼]

Les crises sanitaires font partie des aléas auxquels les forêts gérées sont parfois confrontées. Elles sont susceptibles de se multiplier au cours des décennies à venir, notamment du fait des conséquences attendues des changements globaux. Les acteurs forestiers ont alors à faire face à des évènements qui désorganisent la gestion forestière courante, pouvant conduire à des épisodes de crise qui se déroulent sur plusieurs années (3 à 10 ans). Ce document met à disposition des acteurs forestiers les bonnes pratiques à mettre en œuvre pour affronter les différents évènements liés à une crise sanitaire, sur les plans organisationnels (partenariat, surveillance sanitaire, cellule de crise, communication) et techniques (mobilisation des bois, aménagement et sylviculture, suivi des phénomènes observés). [less ▲]

Maladie hémolytique néonatale modérée

in Revue Médicale de Liège (2012), 67(7-8), 403-406

A Caucasian woman, with a A+ CCD.ee K neg erythrocyte phenotype and no history of blood transfusion, delivered a first child who developed mild anemia. The direct antiglobulin test performed on the ... [more ▼]

A Caucasian woman, with a A+ CCD.ee K neg erythrocyte phenotype and no history of blood transfusion, delivered a first child who developed mild anemia. The direct antiglobulin test performed on the newborn red blood cells belonging to the A+ CCD.ee K neg group, was strongly positive for IgG. During the pregnancy and after the delivery, the woman had a negative irregular antibody screening test, using standard red blood cells. However, at birth, using a collection of thawed red blood cells with rare phenotypes (private antigens), the lab showed an antibody anti-Wra in the maternal serum. The activity of the maternal antibody, with a titer of 16, was completely inhibited by dithiothreitol, indicating the nature IgM of the circulating antibody. The presence of the antigen Wra on the surface of the newborn and its biological father red blood cells was confirmed. The concentration of IgG anti-Wra on baby erythrocytes was demonstrated by the presence of the antibody anti-Wra in the eluate. This case illustrates the difficulties to detect antibodies against private antigens on baby erythrocytes, responsible of hemolytic diseases of newborn. Indeed, standard red blood cell panels used for irregular antibodies screening test do not express generally those private antigens. [less ▲]

Maladie pulmonaire obstructive chronique dans l'espèce équine

in Annales de Médecine Vétérinaire (1996), 140

Equine chronic obstructive pulmonary disease (COPD), also known as <<heaves>>, is a respiratory syndrome associated with stabling or exposure to hay or conditions in which molds or dust prevail. This ... [more ▼]

Equine chronic obstructive pulmonary disease (COPD), also known as <<heaves>>, is a respiratory syndrome associated with stabling or exposure to hay or conditions in which molds or dust prevail. This paper reviews the different aspects of the equine COPD. Etiology, potential evolutions, treatment and prevention of this disease are evolved. [less ▲]

Les maladies à prions. Etude de l'interface neuro-immune et de l'expression de la protéine prion cellulaire au sein des espèces bovine et humaine

Book published by Editions Universitaires Européennes (2010)