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See detailL'hypertension artérielle systolique isolée
Krzesinski, Jean-Marie ULg

Conference (2000, October 18)

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See detailL'hypertension artérielle systolique isolée
Krzesinski, Jean-Marie ULg

Conference (2000, October 18)

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See detailL'hypertension artérielle systolique isolée
Krzesinski, Jean-Marie ULg

Conference (2002, October 12)

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See detailL'hypertension artérielle
Krzesinski, Jean-Marie ULg

Conference (2003, September 18)

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See detailHypertension arterielle: le choix de la première drogue
Krzesinski, Jean-Marie ULg; Rorive, Georges ULg

in Médecine et Hygiène (1987), 45

Depuis plus de dix ans, le traitement de l'hypertension artérielle repose sur la prescription en première ligne des diurétiques et des bêta-bloqueurs. Le fait que ces drogues se soient révélées incapables ... [more ▼]

Depuis plus de dix ans, le traitement de l'hypertension artérielle repose sur la prescription en première ligne des diurétiques et des bêta-bloqueurs. Le fait que ces drogues se soient révélées incapables d'influencer la morbidité et la mortalité coronaire est aujourd'hui présenté comme un argument pour les remplacer dans nos schémas thérapeutiques par des drogues nouvelles à effets vasodilatateurs tels les inhibiteurs de l'enzyme de conversion, les inhibiteurs des flux calciques et les alphabloquants. Les avantages et les inconvénients de cette nouvelle génération de vasodilatateurs demandent cependant à être évalués avec plus de précision avant de pouvoir clairement définir la place respective de ces derniers dans le traitement de l'hypertension artérielle. [less ▲]

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See detailHypertension chez la femme: trois situations particulières
Krzesinski, Jean-Marie ULg

Article for general public (2009)

Dans cette interview du Pr Jean-Marie Krzesinski (Service de Néphrologie, CHU du Sart Tilman, ULg, Liège), seront successivement abordés les problèmes d'hypertension artérielle survenant dans le cadre d ... [more ▼]

Dans cette interview du Pr Jean-Marie Krzesinski (Service de Néphrologie, CHU du Sart Tilman, ULg, Liège), seront successivement abordés les problèmes d'hypertension artérielle survenant dans le cadre d'une contraception orale, de la grossesse ou de la ménopause. Les troubles hypertensifs survenant en cours de grossesse demandent une réeelle surveillance; si l'HTA essentielle bien contrôlée est une affection bénigne, l'apparition d'une pré-éclampsie, constatée chez 5 à 20% des femmes enceintes hypertendues, met en jeu le pronostic maternel et foetal. C'est une urgence. Lors de la ménopause, l'erreur la plus fréquente est de négliger l'accélération du risque cardiovasculaire qui affecte les femmes qui ont perdu leur protection oestrogénique. Leur prise en charge doit être aussi appliquée que chez les hommes d'âge correspondant. [less ▲]

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See detailHypertension durant la grossesse
Krzesinski, Jean-Marie ULg

Conference (2010, May 08)

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See detailL'hypertension est-elle fréquente?
KRZESINSKI, Jean-Marie ULg

Article for general public (2011)

Dans les pays industrialisés, l'hypertension artérielle est une des maladies chroniques les plus fréquentes et sa fréquence augmente avec l'âge. Dans les populations où la consommation de calories et de ... [more ▼]

Dans les pays industrialisés, l'hypertension artérielle est une des maladies chroniques les plus fréquentes et sa fréquence augmente avec l'âge. Dans les populations où la consommation de calories et de sel est faible, l'hypertension est pratiquement inexistante et la pression artérielle n'augmente pas avec l'âge. [less ▲]

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See detailHypertension et diabète
Krzesinski, Jean-Marie ULg; Weekers, Laurent ULg

in Revue Médicale de Liège (2005), 60(5-6, May-Jun), 572-577

Hypertension frequently accompanies diabetes mellitus, as it is present in 50% of diabetic patients. Hypertension can sometimes preceed diabetes. In type 2 diabetes, insulin resistance plays a major role ... [more ▼]

Hypertension frequently accompanies diabetes mellitus, as it is present in 50% of diabetic patients. Hypertension can sometimes preceed diabetes. In type 2 diabetes, insulin resistance plays a major role in the hypertensive risk. In type 1 diabetes, nephropathy is often noted as soon as hypertension is present. Both hypertension and diabetes increase the risk for cardiovascular and renal complications. For their prevention, first of all, modification of the diet with increasing exercise must be proposed, associated to antihypertensive agents with a blood pressure target lower than 130/80 mmHg. Renin-angiotensin blockers constitute the main drug therapy in such patients associated with diuretics or betablocker if angina pectoris is present or even calcium channel blocker when large arteries abnormalities exist. A frequent evaluation of the cardiovascular risk is required together with research of renal dysfunction or microproteinuria. [less ▲]

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See detailHypertension et diabete: a propos d'une association commune mais complexe.
SCHEEN, André ULg; Philips, J.-C.; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2012), 67(3), 133-8

Both diabetes mellitus and arterial hypertension are commonly observed in a single patient. However, the relationship between these two entities is rather complex and there is a great heterogeneity ... [more ▼]

Both diabetes mellitus and arterial hypertension are commonly observed in a single patient. However, the relationship between these two entities is rather complex and there is a great heterogeneity regarding the underlying pathophysiological mechanisms and the clinical presentations. These particularities may have important consequences from a therapeutic point of view, as far as blood pressure targets or even pharmacological strategies are concerned. The present article will discuss the various causes of hypertension in the different types of diabetes, the different forms of hypertension in the diabetic patient, the modalities of treating hypertension in presence of various specific complications (metabolic syndrome, coronary heart disease or renal impairment), and the specificities when hypertension is associated with diabetic cardiovascular autonomic neuropathy. [less ▲]

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See detailHypertension et grossesse
Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (1999), 54(5), 415-423

High blood pressure during pregnancy (BP > or = 140/90 mmHg) is sometimes already noted before conception, with usually a good prognosis (although it could predispose to preeclampsia). alpha-methyldopa is ... [more ▼]

High blood pressure during pregnancy (BP > or = 140/90 mmHg) is sometimes already noted before conception, with usually a good prognosis (although it could predispose to preeclampsia). alpha-methyldopa is the best treatment when needed (agents blocking the renin angiotensin system are not recommended). Preeclampsia, a form of hypertension noted after 20 weeks of gestation with proteinuria is a more serious condition (BP > or = 140/90 mmHg or increase in BP from the 1st trimester > or = 25/15 mmHg). It is generated by placental ischemia and creates maternal endothelial lesions which in turn decrease the blood flow to placenta leading to maternal and fetal syndromes. Hospitalisation is mandatory. No measure other than delivery is known to attenuate or reverse its progression. Treating hypertension during pregnancy (when blood pressure > or = 170/110 mmHg) aims at preventing maternal risk (stroke or eclampsia) but has few effect on foetal lesions. Prevention of this syndrome, which represents the first secondary cause of hypertension, is until now disappointing. [less ▲]

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See detailHypertension intra-crânienne et hydrocéphalie
Martin, Didier ULg

Scientific conference (2005, December)

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See detailHypertension réfractaire : diagnostic et prise en charge
Krzesinski, Jean-Marie ULg

Conference (2012, February 11)

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See detailL'hypertension systolique du sujet âgé
Rorive, Georges ULg; Krzesinski, Jean-Marie ULg

in JAMA (1984)

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See detailHypertension, obesity, is the dietary sodium restriction yet useful?
Krzesinski, Jean-Marie ULg; Janssens, M.; Vanderspeeten, F. et al

in Acta Clinica Belgica (1990, April), 45(5), 359

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See detailHypertension, prévention, traitements et conséquences
Krzesinski, Jean-Marie ULg

Conference (2009, September 22)

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See detailLes hypertensions artérielles d'origine endocrinienne
Beckers, Albert ULg

Scientific conference (1997, October 17)

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See detailLes hypertensions artérielles d'origine endocrinienne.
Beckers, Albert ULg

in Tempo Médical (1998), 196

Les hypertensions artérielles d'origine endocrinienne représentent environ 3 à 5 % des hypertensions artérielles, parmi lesquelles les formes les plus sévères. Lors du diagnostic, une importance ... [more ▼]

Les hypertensions artérielles d'origine endocrinienne représentent environ 3 à 5 % des hypertensions artérielles, parmi lesquelles les formes les plus sévères. Lors du diagnostic, une importance particulière sera accordée à une sémiologie évocatrice. Une cause endocrinienne sera également activement recherchée dans les cas de mauvaises réponses au traitement classique de l'hypertension artérielle. [less ▲]

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See detailHyperthermic induction of the 27-kDa heat shock protein (Hsp27) in neuroglia and neurons of the rat central nervous system.
Krueger-Naug, A. M.; Hopkins, D. A.; Armstrong, J. N. et al

in Journal of Comparative Neurology (The) (2000), 428(3), 495-510

The 27-kDa heat shock protein (Hsp27) is constitutively expressed in many neurons of the brainstem and spinal cord, is strongly induced in glial cells in response to ischemia, seizures, or spreading ... [more ▼]

The 27-kDa heat shock protein (Hsp27) is constitutively expressed in many neurons of the brainstem and spinal cord, is strongly induced in glial cells in response to ischemia, seizures, or spreading depression, and is selectively induced in neurons after axotomy. Here, the expression of Hsp27 was examined in brains of adult rats from 1.5 hours to 6 days after brief hyperthermic stress (core body temperature of 42 degrees C for 15 minutes). Twenty-four hours following hyperthermia, Western blot analysis showed that Hsp27 was elevated in the cerebral cortex, hippocampus, cerebellum, and brainstem. Immunohistochemistry for Hsp27 revealed a time-dependent, but transient, increase in the level of Hsp27 immunoreactivity (Hsp27 IR) in neuroglia and neurons. Hsp27 IR was detected in astrocytes throughout the brain and in Bergmann glia of the cerebellum from 3 hours to 6 days following heat shock. Peak levels were apparent at 24 hours, gradually declining thereafter. In addition, increases in Hsp27 IR were detected in the ependyma and choroid plexus. Hyperthermia induced Hsp27 IR in neurons of the subfornical organ and the area postrema within 3 hours and reached a maximum by 24 hours with a return to control levels 4-6 days after hyperthermia. Specific populations of hypothalamic neurons also showed Hsp27 IR after hyperthermia. These results demonstrate that hyperthermia induces transient expression of Hsp27 in several types of neuroglia and specific populations of neurons. The pattern of induced Hsp27 IR suggests that some of the activated cells are involved in physiological responses related to body fluid homeostasis and temperature regulation. [less ▲]

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See detailHyperthermie chez le cheval: Approche diagnostique clinique
Amory, Hélène ULg

in Proceedings of the Annual meeting of the French Equine Veterinary Association (AVEF) (2003)

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