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See detailIFFT-equivariant quantizations
Boniver, Fabien; Mathonet, Pierre ULg

in Journal of Geometry and Physics (2006), 56(4), 712-730

The existence and uniqueness of quantizations that are equivariant with respect to conformal and projective Lie algebras of vector fields were recently obtained by Duval, Lecomte and Ovsienko. In order to ... [more ▼]

The existence and uniqueness of quantizations that are equivariant with respect to conformal and projective Lie algebras of vector fields were recently obtained by Duval, Lecomte and Ovsienko. In order to do so, they computed spectra of some Casimir operators. We give an explicit formula for those spectra in the general framework of IFFT-algebras classified by Kobayashi and Nagano. We also define tree-like subsets of eigenspaces of those operators in which eigenvalues can be compared to show the existence of IFFT-equivariant quantizations. We apply our results to prove the existence and uniqueness of quantizations that are equivariant with respect to the infinitesimal action of the symplectic (resp. pseudo-orhogonal) group on the symplectic (resp. pseudo-orthogonal) Grassmann manifold. [less ▲]

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See detailIFN gamma inhibits IL-8 production by IL-1bêta and TNFalpha stimulated human chondrocytes
Henrotin, Yves ULg; Zheng, SX; Deby, G et al

in Revue du Rhumatisme (English ed.) (1998), 11

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See detailIFN-gamma and TNF-alpha potentiate prostaglandin D2-induced human eosinophil chemotaxis through up-regulation of CRTH2 surface receptor.
EL SHAZLY, Amr ULg; MOONEN, Vincent ULg; MAWET, Marie et al

in International immunopharmacology (2011), 11(11), 1864-70

Prostaglandin D2 (PGD2) receptor CRTH2, is a pro-inflammatory molecule involved in eosinophil recruitment to the allergic airway. We investigated the expression of CRTH2 in eosinophil from allergic ... [more ▼]

Prostaglandin D2 (PGD2) receptor CRTH2, is a pro-inflammatory molecule involved in eosinophil recruitment to the allergic airway. We investigated the expression of CRTH2 in eosinophil from allergic rhinitis patients (AR) and tested the modulatory role of several TH1 and TH2 cytokines closely related to the allergic immunological response, on the expression of CRTH2 receptor, utilizing human eosinophil cell line (Eol-1).The expression of CRTH2 was tested by immunohistochemistry and flow cytometry (FACS). Chemotaxis was performed in micro-chemotaxis chambers. It is shown that the expression of CRTH2 by eosinophils was significantly higher in the nasal tissue and peripheral blood of AR patients, when compared to control subjects. PGD2 exhibited a typical bell shape dose response in attracting eosinophil from AR patients with optimal activity at 10(-7)M. Eol-1 cell surface expression of CRTH2 was significantly up-regulated by 10ng/ml IFN-gamma and TNF-alpha. The percentage of Eol-1 cells expressing the receptor increased by IFN-gamma and TNF-alpha from 12.74%+/-2.66 to 55%+/-8 and 33.8%+/-9.4, respectively. PGD2-induced Eol-1 chemotaxis was not blocked by SB203580, H-89 Dihydrochloride, Bisindo-lylmaleimide, or Genistein. PGD2-induced Eol-1 chemotaxis was potentiated by IFN-gamma and TNF-alpha without changing the signal transduction pathway. Correlation of our results to peripheral blood eosinophils from allergic rhinitis patients confirmed that 3hour pretreatment of eosinophils by 10ng/ml IFN-gamma and TNF-alpha, increased the mean fluorescence intensity (MFI) of CRTH2 from 8.23 to 9.68 and 9.38, respectively, and potentiated PGD2-induced eosinophil chemotaxis. Our results demonstrate a novel synergism between PGD2, IFN-gamma and TNF-alpha, in eosinophil chemotaxis. [less ▲]

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See detailIFPA Meeting 2012 Workshop Report III: trophoblast deportation, gestational trophoblastic disease, placental insufficiency and fetal growth restriction, trophoblast over-invasion and accreta-related pathologies, placental thrombosis and fibrinolysis.
Al-Khan, A.; Bulmer, J. N.; CHANTRAINE, Frédéric ULg et al

in Placenta (2013), 34 Suppl

Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2012 there were twelve themed workshops, five of which are summarized in this ... [more ▼]

Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2012 there were twelve themed workshops, five of which are summarized in this report. These workshops related to various aspects of placental biology but collectively covered areas of clinical research and pregnancy disorders: 1) trophoblast deportation; 2) gestational trophoblastic disease; 3) placental insufficiency and fetal growth restriction; 4) trophoblast overinvasion and accreta-related pathologies; 5) placental thrombosis and fibrinolysis. [less ▲]

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See detailIGCP 580 - Magnetic susceptibility, correlations and palaeoenvironment.
Da Silva, Anne-Christine ULg; Whalen, Michael; Hladil, Jindrich et al

Conference (2009, September)

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See detailIGCP 580, Magnetic Susceptibility and Gamma-Ray Spectrometry through time. Abstracts book IGCP-580, 4th annual meeting, 24-30th June 2012, Graz, Austria
Kido; Suttner; Piller et al

Book published by Berichte des Institutes für Erdwissenschaften, Karl-Franzens-Universität Graz (2012)

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See detailIGCP-580/596, Geophysical and Geochemical techniques: a window on the Paleozoic world. Abstract book
Whalen; Osadetz; Richards et al

Book published by IGCP-580 (2013)

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See detailIgE antibodies and FceRI are critical components of protective type 2 immunity against honeybee and russell's viper venom in mice
Starkl, Philipp; Marichal, Thomas ULg; Reber, Laurent L. et al

in Proceedings of the Type 2 Cell Symposium - Brugge (2014, December)

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See detailIgE antibodies and FceRI are critical mediators of acquired resistance against honeybee and russell's viper venom in mice
Starkl, Philipp; Marichal, Thomas ULg; Reber, Laurent L. et al

in Proceedings of the EAACI Congress 2014 (2014)

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See detailIgE antibodies critically contribute to acquired enhanced resistance to honeybee venom in mice
Marichal, Thomas ULg; Starkl, Philipp; Reber, Laurent L. et al

Conference (2012, September)

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See detailIgE controlling loci in Czech atopic patients.
Gusareva, Elena ULg; Havelková, Helena; Blažková, Hanna et al

Poster (2006, September 07)

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See detailIgE-mediated anaphylaxis after first intravenous infusion of cyclosporine.
Ebo, D. G.; Piel, Géraldine ULg; Conraads, V. et al

in Annals of Allergy, Asthma & Immunology (2001), 87(3), 243-5

BACKGROUND: Intravenous administration of cyclosporine, which contains Cremophor EL (a polyethoxylated castor oil; BASF, Berlin, Germany), has occasionally resulted in an anaphylactic reaction. An ... [more ▼]

BACKGROUND: Intravenous administration of cyclosporine, which contains Cremophor EL (a polyethoxylated castor oil; BASF, Berlin, Germany), has occasionally resulted in an anaphylactic reaction. An apparent hypersensitivity reaction (bronchospasm and decrease in blood pressure) had occurred during heart transplantation in a 59-year-old woman after intravenous infusion of cyclosporine. Subsequent oral administration of cyclosporine precipitated no reaction. OBJECTIVE: The purpose of this study was to attempt to ascertain the mechanism responsible for the anaphylactic reaction. METHODS: Hypersensitivity investigations, including total serum IgE and allergen-specific IgE quantifications, skin testing, and basophil activation tests by flow cytometric determination of CD63 upregulation were undertaken in the study patient and in two healthy control subjects who were free of medication. RESULTS: The results of intradermal testing with Cremophor EL were positive after 15 minutes in the study patient only. Both cyclosporine and Cremophor EL induced considerable activation of the basophils from our study patient, with an upregulation of CD63 expression from 1% to 39% and 55%, respectively. In contrast, the expression of CD63 on basophils from the two control subjects remained essentially unchanged. CONCLUSIONS: The negative investigative findings in the control subjects, the patient's clinical manifestations in temporal relationship to the infusion, her positive results on intradermal testing with Cremophor, the basophil activation test results, and her uneventful course after oral administration of cyclosporine strongly support the presence of IgE antibodies to Cremophor EL in our patient. [less ▲]

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See detailThe IGF system in in-vitro human decidualization
Ganeff, Corinne ULg; Chatel, G.; Munaut, Carine ULg et al

in Molecular Human Reproduction (2009), 15(1), 27-38

Decidualization of endometrial stromal cells (ESCs) is critical for a successful pregnancy but the molecular mechanisms of the process are poorly understood. In this study, we investigated whether the ... [more ▼]

Decidualization of endometrial stromal cells (ESCs) is critical for a successful pregnancy but the molecular mechanisms of the process are poorly understood. In this study, we investigated whether the insulin-like growth factor (IGF) network is involved in this cellular process. Expression kinetics of members of the IGF system was examined at both mRNA and protein levels during in-vitro decidualization of cultured human ESCs. We found a significant up-regulation of IGF-II as well as of IGF-I receptor and the A and B insulin receptor (InsR) isoforms. In addition, levels of the key adaptor proteins insulin receptor substrate 1 (IRS-1) and IRS-2 increased, suggesting a potential involvement of the IGF signalling pathway in the decidualization process. Expression of two IGF binding proteins, IGFBP-1 and IGFBP-4, which can inhibit IGF action, also increased. In order to determine whether IGF signalling was activated during decidualization, the phosphorylation status of the receptors and the adaptor proteins was estimated. Only IRS-2 was slightly phosphorylated in decidualized cells and was further activated by the addition of exogenous IGF-II. These results suggest that the IGF signalling pathway could play a crucial role in the functions of decidualized endometrial cells [less ▲]

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See detailIGF-1 but not IL-1bêta effects on the proteoglycan production by chondrocytes are regulated by strontium salts
Henrotin, Yves ULg; Labasse, A; Zheng, X et al

in Osteoarthritis and Cartilage (1997), 5

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

in Growth Regulation (1994), 4(suppl 1), 116

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle.
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

Poster (1994)

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See detailIGF-I and IGFBPs in plasma of growing Landrace and large withe pigs.
Messina, M.; Prandi, A.; Nicolas, Nathalie et al

in Proceedings of the 14th IPVS Congress (1996, July)

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See detailIGF-I and IGFBPs in plasma of growing Landrace and Largewhite pigs
Messina, Maria; Prandi, Alberto; Kettmann, Richard ULg et al

in 14th International Pig Veterinary Society Congress (1995)

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