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See detailIGCP 580, Magnetic Susceptibility and Gamma-Ray Spectrometry through time. Abstracts book IGCP-580, 4th annual meeting, 24-30th June 2012, Graz, Austria
Kido; Suttner; Piller et al

Book published by Berichte des Institutes für Erdwissenschaften, Karl-Franzens-Universität Graz (2012)

Detailed reference viewed: 15 (0 ULg)
See detailIGCP-580/596, Geophysical and Geochemical techniques: a window on the Paleozoic world. Abstract book
Whalen; Osadetz; Richards et al

Book published by IGCP-580 (2013)

Detailed reference viewed: 91 (0 ULg)
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See detailIgE antibodies and FceRI are critical components of protective type 2 immunity against honeybee and russell's viper venom in mice
Starkl, Philipp; Marichal, Thomas ULg; Reber, Laurent L. et al

in Proceedings of the Type 2 Cell Symposium - Brugge (2014, December)

Detailed reference viewed: 8 (0 ULg)
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See detailIgE antibodies and FceRI are critical mediators of acquired resistance against honeybee and russell's viper venom in mice
Starkl, Philipp; Marichal, Thomas ULg; Reber, Laurent L. et al

in Proceedings of the EAACI Congress 2014 (2014)

Detailed reference viewed: 15 (1 ULg)
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See detailIgE antibodies critically contribute to acquired enhanced resistance to honeybee venom in mice
Marichal, Thomas ULg; Starkl, Philipp; Reber, Laurent L. et al

Conference (2012, September)

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See detailIgE controlling loci in Czech atopic patients.
Gusareva, Elena ULg; Havelková, Helena; Blažková, Hanna et al

Poster (2006, September 07)

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See detailIgE-mediated anaphylaxis after first intravenous infusion of cyclosporine.
Ebo, D. G.; Piel, Géraldine ULg; Conraads, V. et al

in Annals of Allergy, Asthma & Immunology (2001), 87(3), 243-5

BACKGROUND: Intravenous administration of cyclosporine, which contains Cremophor EL (a polyethoxylated castor oil; BASF, Berlin, Germany), has occasionally resulted in an anaphylactic reaction. An ... [more ▼]

BACKGROUND: Intravenous administration of cyclosporine, which contains Cremophor EL (a polyethoxylated castor oil; BASF, Berlin, Germany), has occasionally resulted in an anaphylactic reaction. An apparent hypersensitivity reaction (bronchospasm and decrease in blood pressure) had occurred during heart transplantation in a 59-year-old woman after intravenous infusion of cyclosporine. Subsequent oral administration of cyclosporine precipitated no reaction. OBJECTIVE: The purpose of this study was to attempt to ascertain the mechanism responsible for the anaphylactic reaction. METHODS: Hypersensitivity investigations, including total serum IgE and allergen-specific IgE quantifications, skin testing, and basophil activation tests by flow cytometric determination of CD63 upregulation were undertaken in the study patient and in two healthy control subjects who were free of medication. RESULTS: The results of intradermal testing with Cremophor EL were positive after 15 minutes in the study patient only. Both cyclosporine and Cremophor EL induced considerable activation of the basophils from our study patient, with an upregulation of CD63 expression from 1% to 39% and 55%, respectively. In contrast, the expression of CD63 on basophils from the two control subjects remained essentially unchanged. CONCLUSIONS: The negative investigative findings in the control subjects, the patient's clinical manifestations in temporal relationship to the infusion, her positive results on intradermal testing with Cremophor, the basophil activation test results, and her uneventful course after oral administration of cyclosporine strongly support the presence of IgE antibodies to Cremophor EL in our patient. [less ▲]

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See detailThe IGF system in in-vitro human decidualization
Ganeff, Corinne ULg; Chatel, G.; Munaut, Carine ULg et al

in Molecular Human Reproduction (2009), 15(1), 27-38

Decidualization of endometrial stromal cells (ESCs) is critical for a successful pregnancy but the molecular mechanisms of the process are poorly understood. In this study, we investigated whether the ... [more ▼]

Decidualization of endometrial stromal cells (ESCs) is critical for a successful pregnancy but the molecular mechanisms of the process are poorly understood. In this study, we investigated whether the insulin-like growth factor (IGF) network is involved in this cellular process. Expression kinetics of members of the IGF system was examined at both mRNA and protein levels during in-vitro decidualization of cultured human ESCs. We found a significant up-regulation of IGF-II as well as of IGF-I receptor and the A and B insulin receptor (InsR) isoforms. In addition, levels of the key adaptor proteins insulin receptor substrate 1 (IRS-1) and IRS-2 increased, suggesting a potential involvement of the IGF signalling pathway in the decidualization process. Expression of two IGF binding proteins, IGFBP-1 and IGFBP-4, which can inhibit IGF action, also increased. In order to determine whether IGF signalling was activated during decidualization, the phosphorylation status of the receptors and the adaptor proteins was estimated. Only IRS-2 was slightly phosphorylated in decidualized cells and was further activated by the addition of exogenous IGF-II. These results suggest that the IGF signalling pathway could play a crucial role in the functions of decidualized endometrial cells [less ▲]

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See detailIGF-1 but not IL-1bêta effects on the proteoglycan production by chondrocytes are regulated by strontium salts
Henrotin, Yves ULg; Labasse, A; Zheng, X et al

in Osteoarthritis and Cartilage (1997), 5

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

in Growth Regulation (1994), 4(suppl 1), 116

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle.
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

Poster (1994)

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See detailIGF-I and IGFBPs in plasma of growing Landrace and large withe pigs.
Messina, M.; Prandi, A.; Nicolas, Nathalie et al

in Proceedings of the 14th IPVS Congress (1996, July)

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See detailIGF-I and IGFBPs in plasma of growing Landrace and Largewhite pigs
Messina, Maria; Prandi, Alberto; Kettmann, Richard ULg et al

in 14th International Pig Veterinary Society Congress (1995)

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See detailIGF-I and their binding proteins in growing horses
Gerin, Daniele; Messina, Maria; Renaville, Robert ULg et al

in 3° Internat. Conf. farm Anim. Endocrinol. (1998)

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See detailIGF-I and their binding proteins in growing horses.
Gerin, Daniele; Messina, Mariella; Renaville, Robert ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1998), 2(special issue), 34

Detailed reference viewed: 15 (1 ULg)
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See detailIGF-I, IGFBP-2 and IGFBP-3 but not GH consentrations are different in normal and poor growing piglets
Saleri, Roberta; Baratta, Mario; Mainardi, G. L. et al

in Reproduction Nutrition Development (2001), 41

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See detailIGF-II in primary human colorectal tumors: peptide level, activated promoters, parental imprinting and gene rearrangement.
Winkler, Rose ULg; Delacroix, Laurence ULg; Bensbaho, K. et al

in Hormone & Metabolic Research (1999), 31(2-3), 148-54

IGF-II is a polypeptide growth factor with growth and differentiation promoting activities, involved in human development. We have reported previously IGF-II mRNA and peptide overexpression in primary ... [more ▼]

IGF-II is a polypeptide growth factor with growth and differentiation promoting activities, involved in human development. We have reported previously IGF-II mRNA and peptide overexpression in primary human colon cancers. Here we show that the IGF-II peptide content is increased in six primary colon cancers compared to the corresponding healthy tissues. The IGF-II transcripts in healthy and cancerous colon tissues were identified by Northern blotting and RT-PCR. Promoters P3 and P4 were active in most tissues. Relaxation of parental imprinting was observed in two tumors and one healthy tissue, without any correlation with the IGF-II transcript levels. Rearrangements of the IGF-II gene in two tumors containing very high amounts of IGF-II mRNA are described. Fragments containing the breakpoints were cloned by the vectorette-PCR strategy. In both tumors, the breakpoints occurred in repetitive sequences. In one tumor (T11), the breakpoint was localized 2 kb downstream the end of exon 9. The second tumor (T18) contains two modified alleles. In one rearranged allele the breakpoint is located in exon 9. The exact position of the breakpoint in the second rearranged allele has not been identified. In future experiments, the correlation between the gene rearrangements and IGF-II mRNA overexpression will be studied. [less ▲]

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See detailIgf2 expression is required for complete immunological tolerance to insulin
Hansenne, Isabelle; Renard, Chantal; Geenen, Vincent ULg

Poster (2007, July)

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See detailIgG fc receptors provide an alternative infection route for murine gamma-herpesvirus-68.
Rosa, Gustavo T; Gillet, Laurent ULg; Smith, Christopher M et al

in PLoS ONE (2007), 2(6), 560

BACKGROUND: Herpesviruses can be neutralized in vitro but remain infectious in immune hosts. One difference between these settings is the availability of immunoglobulin Fc receptors. The question ... [more ▼]

BACKGROUND: Herpesviruses can be neutralized in vitro but remain infectious in immune hosts. One difference between these settings is the availability of immunoglobulin Fc receptors. The question therefore arises whether a herpesvirus exposed to apparently neutralizing antibody can still infect Fc receptor(+) cells. PRINCIPAL FINDINGS: Immune sera blocked murine gamma-herpesvirus-68 (MHV-68) infection of fibroblasts, but failed to block and even enhanced its infection of macrophages and dendritic cells. Viral glycoprotein-specific monoclonal antibodies also enhanced infection. MHV-68 appeared to be predominantly latent in macrophages regardless of whether Fc receptors were engaged, but the infection was not abortive and new virus production soon overwhelmed infected cultures. Lytically infected macrophages down-regulated MHC class I-restricted antigen presentation, endocytosis and their response to LPS. CONCLUSIONS: IgG Fc receptors limit the neutralization of gamma-herpesviruses such as MHV-68. [less ▲]

Detailed reference viewed: 39 (3 ULg)