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Peer Reviewed
See detailImpact of the mesh on the accuracy and efficiency of cardiovascular simulations
Sauvage, E.; Geuzaine, Christophe ULg; Remacle, J.-F. et al

in Proceedings of the ECCOMAS Thematic International Conference on Simulation and Modeling of Biological Flows (SIMBIO 2011) (2011, September)

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See detailImpact of the microbiology in the epuration processes.
Thonart, Philippe ULg; Destain, Jacqueline ULg; Antoine, Patrice et al

in Cerevisia and Biotechnology (1996), 21(2), 76-79

Biological treatments will progressively play a key role in the epuration process. Indeed, they show different advantages like reaction specificity, multiple degradation potentialities and efficiency at ... [more ▼]

Biological treatments will progressively play a key role in the epuration process. Indeed, they show different advantages like reaction specificity, multiple degradation potentialities and efficiency at very low concentrations of pollutants. Two approaches can be considered for developing biological processes of epuration : addition of bioactivators for improving endogenous microorganisms capabilities or introduction of microorganism starters for accelerating the epuration process. These two ways need as prerequisite a basic knowledge of the metabolic pathways for specific compound degradation and of microbial ecology [less ▲]

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See detailImpact of the native-state stability of human lysozyme variants on protein secretion by Pichia pastoris
Kumita, Janet; Johnson, Russel; Alcocer, Marcos et al

in FEBS Journal (2006), 273

We report the secreted expression by Pichia pastoris of two human lysozyme variants F57I and W64R, associated with systemic amyloid disease, and describe their characterization by biophysical methods ... [more ▼]

We report the secreted expression by Pichia pastoris of two human lysozyme variants F57I and W64R, associated with systemic amyloid disease, and describe their characterization by biophysical methods. Both variants have a substantially decreased thermostability compared with wild-type human lysozyme, a finding that suggests an explanation for their increased propensity to form fibrillar aggregates and generate disease. The secreted yields of the F57I and W64R variants from P. pastoris are 200- and 30-fold lower, respectively, than that of wild-type human lysozyme. More comprehensive analysis of the secretion levels of 10 lysozyme variants shows that the low yields of these secreted proteins, under controlled conditions, can be directly correlated with a reduction in the thermostability of their native states. Analysis of mRNA levels in this selection of variants suggests that the lower levels of secretion are due to post-transcriptional processes, and that the reduction in secreted protein is a result of degradation of partially folded or misfolded protein via the yeast quality control system. Importantly, our results show that the human disease-associated mutations do not have levels of expression that are out of line with destabilizing mutations at other sites. These findings indicate that a complex interplay between reduced native-state stability, lower secretion levels, and protein aggregation propensity influences the types of mutation that give rise to familial forms of amyloid disease. [less ▲]

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See detailThe Impact of the New Corporate Governance Code on Belgian Stock Market
Corhay, Albert ULg; Dighaye, Andrée; Michel, Pierre-Armand

in Ali, Paul; Gregoriou, Greg (Eds.) International Corporate Governance after Sarbannes-Oxley (1996)

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See detailImpact of the new solar abundances on the calibration of the PMS binary system RS Chamaeleontis
Alecian, E.; Lebreton, Y.; Goupil, Marie-José et al

in Astronomy and Astrophysics (2007), 473

Context: In a recent work, we tried to obtain a calibration of the two components of the pre-main sequence binary system RS Cha by means of theoretical stellar models. We found that the only way to ... [more ▼]

Context: In a recent work, we tried to obtain a calibration of the two components of the pre-main sequence binary system RS Cha by means of theoretical stellar models. We found that the only way to reproduce the observational parameters of RS Cha with standard stellar models is to decrease the initial abundances of carbon and nitrogen derived from the GN93 solar mixture of heavy elements by a few tenths of dex. Aims: In this work, we aim to reproduce the observational properties of the RS Cha stars with stellar evolution models based on the new AGS05 solar mixture recently derived from a three-dimensional solar model atmosphere. The AGS05 mixture is depleted in carbon, nitrogen and oxygen with respect to the GN93 mixture. Methods: We calculated new stellar models of the RS Cha components using the AGS05 mixture and appropriate opacity tables. We sought models that simultaneously satisfy the observations of the two components (masses, radii, luminosities, effective temperatures and metallicity). Results: We find that it is possible to reproduce the observational data of the RS Cha stars with AGS05 models based on standard input physics. From these models, the initial helium content of the system is YË 0.255 and its age is Ë 9.13 ± 0.12 Myr. [less ▲]

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See detailThe Impact of the OECD and UN Model Conventions on Bilateral Tax Treaties: 4. Belgium
Richelle, Isabelle ULg; Traversa, Edoardo

in Lang, Michael; Pistone, Pasquale; Schuch, Josef (Eds.) et al The Impact of the OECD and UN Model Conventions on Bilateral Tax Treaties (2012)

This book provides an analysis of bilateral tax treaties concluded by thirty-seven jurisdictions from five continents and empirically ascertains the impact of the UN and OECD Model Tax Conventions on ... [more ▼]

This book provides an analysis of bilateral tax treaties concluded by thirty-seven jurisdictions from five continents and empirically ascertains the impact of the UN and OECD Model Tax Conventions on bilateral tax treaties. It therefore fills a major gap in the international tax literature, which has so far either studied the sole Model Tax Conventions or focused on bilateral treaties in the context of the tax treaty policy of single countries, and sets the pace for a new methodology in the analysis and interpretation of tax treaties. A general report outlines the key points of the analysis, highlights current trends and predicts future developments of multilateralism and global tax law. This is an essential resource for academics, tax authorities and international tax practitioners who find textbooks based on Model Tax Conventions insufficient. • First study of tax treaties to adopt a global perspective • Demonstrates the impact of the OECD and UN Model Conventions via independent expert analysis and supplemented by a general report • Sets new standards for tax treaty interpretation by turning bilateral treaties into a possible core for developing multilateralism in global tax law [less ▲]

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See detailImpact of the pCO2 level on microalgae. Comparison of past, present and futur situations during mesocosms experiments. II- species diversity of diatoms
Huonnic, P.; Martin-Jézéquel, V.; Rincé, Y. et al

Poster (2004, October)

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See detailImpact of the pCO2 level on microalgae. Comparison of past, present & futur situations during mesocosms experiments.
Martin-Jézéquel, V.; Huonnic, P.; Delille, Bruno ULg et al

Poster (2004, October)

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See detailImpact of the plant protection practices on the operators' exposure: survey by the communes and ministry of equipment and transport (MET-RW)
Godeaux, Denis; Schiffers, Bruno ULg; Culot, Marc ULg

in Communications in Agricultural and Applied Biological Sciences (2008)

In order to gain a better understanding of non-agricultural pesticide use and to prepare the legislative and technical dossiers required under the Water Framework Directive, between October 2006 and March ... [more ▼]

In order to gain a better understanding of non-agricultural pesticide use and to prepare the legislative and technical dossiers required under the Water Framework Directive, between October 2006 and March 2007, two surveys were conducted of 97 Walloon communes and 65 districts of the Walloon Ministry of Public Works and Transport (MET) (General Directorates for Motorways and Roads and for Waterway Infrastructure). The questionnaire (26 questions on six topics) was sent by e-mail or fax, with a response rate of 60 out of 97 communes and 33 out of 65 districts. This article describes the health-related aspects of the surveys (environmental aspects are the subject of separate article). The surveys have brought to light a number of bad practices and a growing awareness of the non-agricultural users with respect to health risks. However, bad habits, legislation infringements and a failure to follow good plant protection practice are still a problem and pose major health risks (which endanger the operator and the public). Information, awareness-raising and, especially, training of people therefore remain a priority for nonagricultural users. [less ▲]

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See detailImpact of the presence of a clinical pharmacist in university hospital wards on the elderly or polymedicated patients care
Tshibungu Diambi, Annie; D'Orio, Vincenzo ULg; Delporte, Jean-Pierre ULg et al

in Pharmakon (2009, February), 41(1), 21

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See detailImpact of the presence of a clinical pharmacist in university hospital wards on the elderly or polymedicated patients care
Van Hees, Thierry ULg; Delporte, Jean-Pierre ULg; Petermans, Jean ULg

in Journal of Nutrition, Health & Aging (The) (2009, June), 13(Supplement 1), 465

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See detail« The impact of the rulings of the European Court of Justice in the area of direct taxation » 2010 update 2011
Malherbe, Jacques; Malherbe, Philippe; Richelle, Isabelle ULg et al

Report (2011)

This study describes the impact of the rulings of the European Court of Justice (respectively now the Court of Justice of the European Union) on Members States’ direct tax systems. It is the updated ... [more ▼]

This study describes the impact of the rulings of the European Court of Justice (respectively now the Court of Justice of the European Union) on Members States’ direct tax systems. It is the updated version (as of 31 December 2010) of the study PE 404.888 published in 2008. The case-law of the Court is characterised by its continuing development in a changing institutional, political, social and economic context. The area of taxation, and in particular the area of international taxation, is also an evolvingfield,in which conflicting or converging interests between states, or between states and taxpayers, play an important role in the shaping of the applicable national rules, which face new realities due to economic globalisation. Focusing on an analysis of the Court’s judgments, particular attention is also paid to major trends in the implementation of the Court’s case-law by Member States. Finally, the limits of the so-called 'negative integration' through the case-law of the Court are discussed and suggestions are made for possible further European action, notably the adoption of legislative acts in direct tax matters. [less ▲]

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See detailThe impact of the salience of fluency in recognition memory in Alzheimer’s disease
Simon, Jessica ULg; Bastin, Christine ULg; SALMON, Eric ULg et al

Poster (2013, December 06)

According to the dual-process models, recognition memory is supported by recollection and familiarity (Yonelinas, 2002). Familiarity is a complex function that depends on several processes. One of the ... [more ▼]

According to the dual-process models, recognition memory is supported by recollection and familiarity (Yonelinas, 2002). Familiarity is a complex function that depends on several processes. One of the most important mechanisms is the sense of familiarity driven by the fluency processing (Whittlesea, 1993). The fluency can be defined by the enhancement of processing speed and the ease of processing due to an earlier encounter with the stimulus. Our objective is to explore the effect on an increase of salience of fluency cues on the recognition memory performance of patients with Alzheimer disease (AD). Sixteen AD patients and sixteen healthy elderly controls (HC) performed two conditions of a memory task. In the study phase, 25 words were presented at a rate of one word every 1.5s. Participants were instructed to read the words aloud and to try and remember them. After a break of 5 minutes, participant performed a yes/no recognition task with 25 studied words and 25 new words. In the Non-Overlap condition, the 25 studied words were composed of a subset of letters of the alphabet and the 25 new words of the remaining letters. In the Overlap condition, the 50 words were based on the whole alphabet. The two recognition tasks were separated by a delay of 24h. The capacity to discriminate between old and new items was measured by the index d’. An ANOVA on d’ scores revealed that discrimination was poorer in the AD group than in the HC and also poorer in the Overlap condition than in the Non-Overlap condition. The current results showed that to increase salience of fluency at the level of letter by eliminating letter-overlap between old and new words increases the recognition performance to the same extent in both groups but the amplitude of AD memory deficit was not reduced (Bastin, Willems, Genon, & Salmon, 2013). [less ▲]

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See detailImpact of the somatotrope Growth Hormone (GH)/Insulin-like Growth Factor 1 (IGF-1) axis upon thymus function: Pharmacological implications in regeneration of immune functions
Goffinet, Lindsay ULg; Mottet, Marie ULg; Kermani, Hamid et al

in Immunology, Endocrine & Metabolic Agents - Medicinal Chemistry (2011), 11

The thymus is the central lymphoid structure where T-cell differentiation takes place, and a crucial organ for the maintenance of homeostasis in the immune system. Thymopoiesis includes intrathymic ... [more ▼]

The thymus is the central lymphoid structure where T-cell differentiation takes place, and a crucial organ for the maintenance of homeostasis in the immune system. Thymopoiesis includes intrathymic proliferation of T-cell precursors, selection and output of both self-tolerant and competent effector T cells, as well as of natural regulatory T cells (nTreg). In the crosstalk between the neuroendocrine and immune systems, peptide hormones have been more and more implicated in immunomodulation for the last thirty years. The somatotrope growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis in particular has been repeatedly shown to play a major regulatory role upon thymus function and T-cell development. This review will focus on the important thymotropic properties of the somatotrope GH/IGF-1 axis, and will try to discriminate these properties in function of the endocrine or paracrine/autocrine pathways involved in their mediation. Most importantly, in light of an increasing number of recent studies, GH and IGF-1 now appear as a novel therapeutic agents that could be used for enhancing thymopoiesis in different cases of immune deficiencies, including aging-related immune dysfunction. [less ▲]

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See detailImpact of the spatial resolution on the Greenland Ice Sheet Surface Mass Balance modelling using the regional climate model MAR with the aim to force an ice sheet model.
Franco, Bruno ULg; Fettweis, Xavier ULg; Erpicum, Michel ULg

Poster (2011, April 05)

By using the regional climate model MAR (Modèle Atmosphérique Régional), validated for Greenland at 25km resolution and forced every 6 hours with the ERA-INTERIM reanalysis (Fettweis 2007, Fettweis et al ... [more ▼]

By using the regional climate model MAR (Modèle Atmosphérique Régional), validated for Greenland at 25km resolution and forced every 6 hours with the ERA-INTERIM reanalysis (Fettweis 2007, Fettweis et al. 2010), we have modelled the Greenland Ice Sheet (GrIS) Surface Mass Balance (SMB) at 20, 25, 30, 40 and 50km resolution to assess the impact of the spatial resolution. As part of the ICE2SEA project, the 25km-resolution SMB outputs of the MAR model are used as forcing fields for ice sheet models, in order to produce future projections of the GrIS contribution to sea-level rise over the next 200 years. Although the current spatial resolution of the MAR model (25km) is much higher than the general circulation models (GCM) resolution (150-300km), the ice sheet models often run at a higher resolution (typically 5-10km). Nevertheless, such higher-resolution runs of the MAR model on the same integration domain generate a significant additional computing time and are not doable until now. Moreover, conventional linear interpolations of the SMB outputs onto a higher-resolution grid, generally induce biases because ice sheet masks at different spatial resolutions do not match and the SMB is a very complex function of the spatial resolution and the topography . That is why several enhanced SMB interpolations are tested here in order to reduce biases when interpolating the MAR outputs onto higher resolution, in the framework of the ICE2SEA project. [less ▲]

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See detailImpact of the spray drying conditions on inulin's physical properties
Ronkart, Sébastien; Blecker, Christophe ULg; Deroanne, Claude et al

Poster (2008, July)

Detailed reference viewed: 23 (8 ULg)
See detailImpact of the Structure of Biocompatible Aliphatic Polycarbonate on siRNA Transfection Ability
Frère, Antoine ULg; Kawalec, Michal; Tempelaar, Sarah et al

Conference (2014, May 26)

Detailed reference viewed: 43 (16 ULg)