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See detailExposure assessment of salmonella in pork in Belgium
Ghafir, Y.; China, B.; Dierick, K. et al

Poster (2004, October 03)

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See detailExposure factors influencing serum dioxin concentrations in the French dioxin and incinerators study
Frery, N.; Zeghnoun, A.; Sarter, H. et al

in Organohalogen Compounds (2007), 69

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See detailExposure of several Belgian consumer groups to pesticide residues through fresh fruit and vegetable consumption
Claeys, Wendie L.; Schmit, Jean-François; Bragard, Claude et al

in Food Control (2011), 22(3-4), 508-516

The output of a pesticide surveillance program (detection frequency and number of exceeding measures) can lead to unnecessary concern among consumers since they lack information concerning the actual ... [more ▼]

The output of a pesticide surveillance program (detection frequency and number of exceeding measures) can lead to unnecessary concern among consumers since they lack information concerning the actual exposure. In this study, the exposure to pesticide residues through fruit and vegetable consumption is evaluated based on the 2008 surveillance data of the Belgian Federal Agency for the Safety of the Food Chain (FASFC). Results (deterministic and probabilistic approach) demonstrate that the chronic exposure of the adult population (>15 years) is generally under control, even at high or frequent consumption of fruit and vegetables. For most of the pesticide residues studied, the exposure is one hundred times lower than the ‘acceptable daily intake’ or ADI. With regard to children (2e5 years) who consume regularly or large amounts of fruit and vegetables, there are however, indications that for some pesticides the ADI can be exceeded. Nevertheless, due to the large uncertainty in these calculations, a more detailed study is required for this vulnerable group of consumers. In addition, it was demonstrated that washing and peeling of fruit and vegetables result in an exposure that is probably five to six times lower. [less ▲]

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See detailExposure to an organochlorine pesticide (chlordecone) and development of 18-month-old infants
Boucher, O; Simard, M.-N.; Muckle, G et al

in NeuroToxicology (2013), 35(1), 162-168

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See detailExposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages.
Sabatel, Catherine ULg; Radermecker, Coraline ULg; Fievez, Laurence ULg et al

in Immunity (2017), 46(3), 457-473

Living in a microbe-rich environment reduces the risk of developing asthma. Exposure of humans or mice to unmethylated CpG DNA (CpG) from bacteria reproduces these protective effects, suggesting a major ... [more ▼]

Living in a microbe-rich environment reduces the risk of developing asthma. Exposure of humans or mice to unmethylated CpG DNA (CpG) from bacteria reproduces these protective effects, suggesting a major contribution of CpG to microbe-induced asthma resistance. However, how CpG confers protection remains elusive. We found that exposure to CpG expanded regulatory lung interstitial macrophages (IMs) from monocytes infiltrating the lung or mobilized from the spleen. Trafficking of IM precursors to the lung was independent of CCR2, a chemokine receptor required for monocyte mobilization from the bone marrow. Using a mouse model of allergic airway inflammation, we found that adoptive transfer of IMs isolated from CpG-treated mice recapitulated the protective effects of CpG when administered before allergen sensitization or challenge. IM-mediated protection was dependent on IL-10, given that Il10-/- CpG-induced IMs lacked regulatory effects. Thus, the expansion of regulatory lung IMs upon exposure to CpG might underlie the reduced risk of asthma development associated with a microbe-rich environment. [less ▲]

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See detailExposure to chlordecone and male fertility in Guadeloupe (French West Indies)
Multigner, L.; Kadhel, P.; Huc-Terki, F. et al

in Epidemiology (2006, November), 17(6, Suppl. S), 372

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See detailExposure to endocrine disrupting chemicals and neurodevelopmental alterations.
Pinson, Anneline ULg; Bourguignon, Jean-Pierre ULg; Parent, Anne-Simone ULg

in Andrology (2016), 4(4), 706-22

The developing brain is remarkably malleable as neural circuits are formed and these circuits are strongly dependent on hormones for their development. For those reasons, the brain is very vulnerable to ... [more ▼]

The developing brain is remarkably malleable as neural circuits are formed and these circuits are strongly dependent on hormones for their development. For those reasons, the brain is very vulnerable to the effects of endocrine-disrupting chemicals (EDCs) during critical periods of development. This review focuses on three ubiquitous endocrine disruptors that are known to disrupt the thyroid function and are associated with neurobehavioral deficits: polychlorinated biphenyls, polybrominated diphenyl ethers, and bisphenol A. The human and rodent data suggesting effects of those EDCs on memory, cognition, and social behavior are discussed. Their mechanisms of action go beyond relative hypothyroidism with effects on neurotransmitter release and calcium signaling. [less ▲]

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See detailExposure to oestrogen prenatally does not interfere with the normal female-typical development of odour preferences
Bakker, Julie ULg; De Mees, C.; Szpirer, J. et al

in Journal of Neuroendocrinology (2007), 19(5), 329-334

The neural mechanisms controlling mate recognition and heterosexual partner preference are sexually differentiated by perinatal actions of sex steroid hormones. We previously showed that the most ... [more ▼]

The neural mechanisms controlling mate recognition and heterosexual partner preference are sexually differentiated by perinatal actions of sex steroid hormones. We previously showed that the most important action of oestrogen during prenatal development is to defeminise and, to some extent, masculinise brain and behaviour in mice. Female mice deficient in alpha-foetoprotein (AFP) due to a targeted mutation in the Afp gene (AFP-KO) do not show any female sexual behaviour when paired with an active male because they lack the protective action of AFP against maternal oestrogens. In the present study, we investigated whether odour preferences, another sexually differentiated trait in mice, are also defeminised and/or masculinised in AFP-KO females due to their prenatal exposure to oestrogens. AFP-KO females of two background strains (CD1 and C57Bl/6j) preferred to investigate male over female odours when given the choice between these two odour stimuli in a Y-maze, and thus remained very female-like in this regard. Thus, the absence of lordosis behaviour in these females cannot be explained by a reduced motivation of AFP-KO females to investigate male-derived odours. Furthermore, the presence of a strong male-directed odour preference in AFP-KO females suggests a postnatal contribution of oestrogens to the development of preferences to investigate opposite-sex odours. [less ▲]

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See detailExpresión de antígenos de rotavirus bovino en plantas de alfalfa transgénicas: su utilización como inmunógeno y/o agente antiviral
Mozgovoj, M.; Wigdorovitz, A.; Dus Santos, M.J. et al

Poster (2002, September 23)

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See detailExpresión de la glicoproteína gp53 del virus de la diarrea viral bovina en plantas transgénicas de alfalfa
Gómez, C.; Dus Santos, M.J.; Mozgovoj, M. et al

Poster (2002, September 23)

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See detailExpresión de la proteína p24 del Virus de la Leucosis Bovina en E. coli y su potencial utilización en pruebas de diagnostico
Gutiérrez, G.; Álvarez, I.; Rodriguez, Sabrina ULg et al

Poster (2004, November 14)

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See detailExpressing female fertility in the Walloon region of Belgium: how to do?
Vanderick, Sylvie ULg; Bastin, Catherine ULg; Gengler, Nicolas ULg

Conference (2009, August)

Since September 2007, the Walloon Region of Belgium has used a genetic evaluation system for pregnancy rate in Holsteins and has participated in 3 of the 5 MACE trait INTERBULL runs for female fertility ... [more ▼]

Since September 2007, the Walloon Region of Belgium has used a genetic evaluation system for pregnancy rate in Holsteins and has participated in 3 of the 5 MACE trait INTERBULL runs for female fertility. In order to define general way of female fertility expression, a principal component analysis was carried out on six published foreign female fertility indexes. Results of were used to compute a direct female fertility index with the INTERBULL international female fertility proofs available on the Walloon scale. An indirect female fertility index was also developed in order to increase reliability of young bulls. Approximate procedure based on selection index was used to combine both indexes in an overall index called combined female fertility index. This index was highly correlated with the direct female fertility index (.96) and the first principal component (.85), therefore it was considered as good expression of female fertility. Moreover, this allowed recovering 4,019 INTERBULL bulls with a publishable female fertility index. [less ▲]

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See detailExpressing female fertility in the Walloon region of Belgium: how to do?
Vanderick, Sylvie ULg; Bastin, Catherine ULg; Gengler, Nicolas ULg

in Interbull Bulletin (2009), 40

Since September 2007, the Walloon Region of Belgium has used a genetic evaluation system for pregnancy rate in Holsteins and has participated in 3 of the 5 MACE trait INTERBULL runs for female fertility ... [more ▼]

Since September 2007, the Walloon Region of Belgium has used a genetic evaluation system for pregnancy rate in Holsteins and has participated in 3 of the 5 MACE trait INTERBULL runs for female fertility. In order to define general way of female fertility expression, a principal component analysis was carried out on six published foreign female fertility indexes. Results of were used to compute a direct female fertility index with the INTERBULL international female fertility proofs available on the Walloon scale. An indirect female fertility index was also developed in order to increase reliability of young bulls. Approximate procedure based on selection index was used to combine both indexes in an overall index called combined female fertility index. This index was highly correlated with the direct female fertility index (.96) and the first principal component (.85), therefore it was considered as good expression of female fertility. Moreover, this allowed recovering 4,019 INTERBULL bulls with a publishable female fertility index. [less ▲]

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See detailExpression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies
Poppe, B.; Vandesompele, J.; Schoch, C. et al

in Blood (2004), 103(1), 229-235

MLL amplification was recently recognized as a recurrent aberration in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), associated with adverse prognosis and karyotype complexity. Here we ... [more ▼]

MLL amplification was recently recognized as a recurrent aberration in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), associated with adverse prognosis and karyotype complexity. Here we present detailed results of fluorescence in situ hybridization (FISH) and expression analyses of MLL and 5 selected 11q candidate oncogenes (CBL, DDX6, ETS1, FLI1, and PLZF) in 31 patient samples and one cell line with 11q23 gain. FISH analyses revealed that the 11q23 amplicon invariably encompassed MLL, DDX6, ETS1, and FLI1, whereas expression analyses identified MLL and DDX6 as the most differentially expressed genes among samples with and without 11q23 copy gain or amplification. In MLL-amplified samples, a significant transcriptional up-regulation of MEIS1, PROML1, ADAM10, NKG2D, and ITPA was noted. Further analyses, designed to elucidate a possible role of the 11q overexpressed genes (MLL, DDX6, FLI1, and ETS1) in unselected MDS and AML samples, revealed a significant upregulation of MLL in MDS. Our findings confirm the MLL gene as a prominent target of 11q23 amplification and provide further evidence for an etiologic role for MLL gain of function in myeloid malignancies. In addition, our results indicate that the transcriptional program associated with MLL rearrangements and MLL overexpression displays significant similarities. [less ▲]

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See detailExpression analysis of IL-22 and bioactivity of its recombinant protein in rainbow trout (Oncorhynchus mykiss).
Mira Monte, Milena ULg; Zou, Jun; Carrington, Allison et al

Poster (2009)

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See detailExpression And Activity Of Antioxidant Enzymes During Potato Tuber Dormancy
Rojas-Beltran, Ja.; Dejaeghere, F.; Kotb, Ma. et al

in Potato Research (2000), 43(4),

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See detailExpression and function of DRC-1 antigen.
Bosseloir, A. L.; Antoine, Nadine ULg; Heinen, Ernst ULg et al

in Advances in Experimental Medicine and Biology (1994), 355

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