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See detailImplementation of genomic arrays in prenatal diagnosis: the Belgian approach to meet the challenges.
Vanakker, Olivier; Vilain, Catheline; Janssens, Katrien et al

in European journal of medical genetics (2014), 57(4), 151-6

After their successful introduction in postnatal testing, genome-wide arrays are now rapidly replacing conventional karyotyping in prenatal diagnostics. While previous studies have demonstrated the ... [more ▼]

After their successful introduction in postnatal testing, genome-wide arrays are now rapidly replacing conventional karyotyping in prenatal diagnostics. While previous studies have demonstrated the advantages of this method, we are confronted with difficulties regarding the technology and the ethical dilemmas inherent to genomic arrays. These include indication for testing, array design, interpretation of variants and how to deal with variants of unknown significance and incidental findings. The experiences with these issues reported in the literature are most often from single centres. Here, we report on a national consensus approach how microarray is implemented in all genetic centres in Belgium. These recommendations are subjected to constant re-evaluation based on our growing experience and can serve as a useful tool for those involved in prenatal diagnosis. [less ▲]

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See detailImplementation of health aspects (ER N°3) in the Construction Products; Directive (CPD) regarding emissions to indoor air
Lor, Marc; Vause, Kevin; Goelen, Eddy et al

Poster (2008)

Standardisation work on test methods for dangerous substances released in the indoor air by construction products is currently ongoing at European level. The paper presents a study conducted in Belgium ... [more ▼]

Standardisation work on test methods for dangerous substances released in the indoor air by construction products is currently ongoing at European level. The paper presents a study conducted in Belgium, which compares methods in three different test chambers and aiming at assessing the performance of the products placed on the market. [less ▲]

Detailed reference viewed: 30 (4 ULg)
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See detailImplementation of hydrostatic constraint in the software DIVA: Theory and applications
Troupin, Charles ULg; Ouberdous, Mohamed ULg; Rixen, Michel et al

Poster (2008, March 31)

Detailed reference viewed: 10 (1 ULg)
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See detailImplementation of interactive visualization of models and students data
Mazza, R; Mazzola, L; Glahn, C et al

Report (2009)

This document reports the implementation design of the interactive visualizations of open learner models that will be performed in GRAPPLE. The visualizations will be based on data stored in the domain ... [more ▼]

This document reports the implementation design of the interactive visualizations of open learner models that will be performed in GRAPPLE. The visualizations will be based on data stored in the domain model, conceptual adaptation model, and user model, and aim at supporting learners to be more engaged in the learning process, and instructors in assisting the learners. [less ▲]

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See detailImplementation of LEAN and BIM processes into an innovative Building Construction System.
Schmitz, Dimitri ULg

Conference (2012)

The Building Construction System « Upbrella » proposes a new concept for the erection of high-rise buildings and offers a controlled and isolated work environment by integrating a protective mobile roof ... [more ▼]

The Building Construction System « Upbrella » proposes a new concept for the erection of high-rise buildings and offers a controlled and isolated work environment by integrating a protective mobile roof and wall during construction. Therefore lower floors could be occupied once their construction is completed, while other higher floors are still under construction.We aim to explore, using a design science approach, how the overall construction phase could be optimized the by integrating some of BIM and LEAN construction processes within the Upbrella system. A first six-story building will be erected from June 2012 in order to test the system. The building will be built in two phases (3 floors per phase). The first phase will consist of a traditional construction without the Upbrella system and the second phase will use the Upbrella system. [less ▲]

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See detailImplementation of marker-assisted selection: practical lessons from dairy cattle
Boichard, D.; Fritz, S.; Rossignol, M. N. et al

in Proceedings of the 8th World Congress on Genetics Applied to Livestock Production (2006)

Detailed reference viewed: 18 (0 ULg)
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See detailImplementation of micropollutant fate in wastewater treatment plant benchmark simulation models
Pons, Marie-Noëlle; Louvet, Jean-Noël ULg; Potier, Olivier

Conference (2010)

Detailed reference viewed: 26 (1 ULg)
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See detailImplementation of new Fast-GC-MS and UHPLC-MS/MS data in a conventional GC-MS database for heroin profiling
Debrus, Benjamin ULg; Broséus, Julian; Guillarme, Davy et al

Conference (2009, October)

Detailed reference viewed: 56 (11 ULg)
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See detailAn implementation of on-line transient stability screening and control using distributed processing
N'Guessan, Alexandre; Pavella, Mania ULg; Wehenkel, Louis ULg

in Proc. of Intelligent Systems Application to Power Systems (2003)

This paper describes the implementation of an online transient stability assessment software, composed of algorithms for contingency screening and for the design of preventive control actions. The ... [more ▼]

This paper describes the implementation of an online transient stability assessment software, composed of algorithms for contingency screening and for the design of preventive control actions. The implementation of the two parts rely on a hybrid method called SIME, coupled with a time domain simulation engine and power flow program. The speed up of the contingency screening module is obtained by distributing contingencies on a cluster of computers to comply with extended real-time speed requirements. A compensation scheme is used to determine active power rescheduling alternatives in order to stabilize the dangerous contingencies identified at the screening step. The software has been coupled with an industrial EMS platform, and tested in the simulation environment. [less ▲]

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See detailImplementation of simple logic gates on gold-ammonia bonding patterns in different charge states
Kryachko, Eugène ULg; Remacle, Françoise ULg

in Molecular Physics (2008), 106(2-4), 521-530

An approach is proposed for encoding the gold-ammonia bonding patterns on the conformational manifold of the Au-n(Z)-(NH3)(m), Z=0, +/- 1, clusters in order to implement simple unary and binary logic gate ... [more ▼]

An approach is proposed for encoding the gold-ammonia bonding patterns on the conformational manifold of the Au-n(Z)-(NH3)(m), Z=0, +/- 1, clusters in order to implement simple unary and binary logic gate operations. The gold-ammonia bonding patterns are governed by two different basic ingredients: the anchoring Au-N bond and the nonconventional N-H center dot center dot center dot Au hydrogen bond, and exhibit distinct characteristics as the charge of the cluster varies within Z = 0, +/- 1. The conformers of the small cluster, Au-Z-(NH3)(2), and of the nanometric size one, Au-20(Z), are chosen as illustrative examples. The dependence of the bonding patterns on the overall charge state of the cluster allows to implement the logic gates NOT, FAN-OUT, AND, NAND, OR, NOR, INH, XOR, and XNOR and to identify the outputs using an IR readout protocol. [less ▲]

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See detailImplementation of structured metal packing for the design of biofilm reactor : analysis by high energy X-ray tomography and application to the production of lipopeptides by Bacillus subtilis
Zune, Quentin; Soyeurt, Delphine; Ongena, Marc ULg et al

Poster (2012, October 08)

1. Whereas multi-species biofilm reactors are commonly used for treatments of water and gas effluents, new strategies are arising for the development of mono-species biofilm reactors in order to produce ... [more ▼]

1. Whereas multi-species biofilm reactors are commonly used for treatments of water and gas effluents, new strategies are arising for the development of mono-species biofilm reactors in order to produce high added value molecules. Thus, it is required to design new bioreactors able to promote the growth of the biomass on the form of a biofilm and to identify the key physico-chemical parameters involved in order to optimize the bioprocess. 2. Aim of this study was to investigate a pilot-scale biofilm reactor comprising a metal structured packing promoting growth of Bacillus subtilis as a biofilm for the production of lipopeptides, high added value compounds with high surface active properties. 3. In this work, the mechanical stirring system of a 20L stirred tank bioreactor has been removed and replaced by a metal structured packing positioned in the headspace of the vessel above a liquid phase. The culture medium is continuously recirculated on the packing thanks to a peristaltic pump and air supply is performed just above the liquid phase under the packing. High energy X-ray tomography was used to estimate non-invasively the biofilm distribution inside the packing and permitted to define parameters that affect scale-up. Performances of the biofilm reactor were compared with a submerged culture in a stirred tank reactor in terms of lipopeptides production. 4. After 72 hours of fermentation, 94 % of the total biomass adheres onto the metal packing on the form of a biofilm. The colonization of this latter has been visualized non-invasively by X-ray tomography directly inside the packing and shows a conical repartition of the biofilm mass (about 25% of the total volume of the packing) as well as the presence of clogging. However, unlike the submerged culture, no foam formation appeared during fermentation and surfactin yield reaches 345,4 ± 32,8 mg / L for the biofilm reactor against 277,3 ± 34,4 mg / L in the stirred tank reactor. 5. In conclusion, this experimental setting leads to a major technological progress avoiding foam formation and increasing surfactin production. Nevertheless, significant improvements are required at the level of the biofilm distribution in thin layers inside the packing in order to increase mass transfer and lipopeptides recoveries. Further investigations will be devoted to the optimization of the physico-chemical parameters involved in biofilm distribution. [less ▲]

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See detailImplementation of structured metal packing for the design of biofilm reactor : analysis by high energy X-ray tomography and application to the production of lipopeptides by Bacillus subtilis
Zune, Quentin ULg; Soyeurt, Delphine; Ongena, Marc ULg et al

Poster (2012, October 08)

1. Whereas multi-species biofilm reactors are commonly used for treatments of water and gas effluents, new strategies are arising for the development of mono-species biofilm reactors in order to produce ... [more ▼]

1. Whereas multi-species biofilm reactors are commonly used for treatments of water and gas effluents, new strategies are arising for the development of mono-species biofilm reactors in order to produce high added value molecules. Thus, it is required to design new bioreactors able to promote the growth of the biomass on the form of a biofilm and to identify the key physico-chemical parameters involved in order to optimize the bioprocess. 2. Aim of this study was to investigate a pilot-scale biofilm reactor comprising a metal structured packing promoting growth of Bacillus subtilis as a biofilm for the production of lipopeptides, high added value compounds with high surface active properties. 3. In this work, the mechanical stirring system of a 20L stirred tank bioreactor has been removed and replaced by a metal structured packing positioned in the headspace of the vessel above a liquid phase. The culture medium is continuously recirculated on the packing thanks to a peristaltic pump and air supply is performed just above the liquid phase under the packing. High energy X-ray tomography was used to estimate non-invasively the biofilm distribution inside the packing and permitted to define parameters that affect scale-up. Performances of the biofilm reactor were compared with a submerged culture in a stirred tank reactor in terms of lipopeptides production. 4. After 72 hours of fermentation, 94 % of the total biomass adheres onto the metal packing on the form of a biofilm. The colonization of this latter has been visualized non-invasively by X-ray tomography directly inside the packing and shows a conical repartition of the biofilm mass (about 25% of the total volume of the packing) as well as the presence of clogging. However, unlike the submerged culture, no foam formation appeared during fermentation and surfactin yield reaches 345,4 ± 32,8 mg / L for the biofilm reactor against 277,3 ± 34,4 mg / L in the stirred tank reactor. 5. In conclusion, this experimental setting leads to a major technological progress avoiding foam formation and increasing surfactin production. Nevertheless, significant improvements are required at the level of the biofilm distribution in thin layers inside the packing in order to increase mass transfer and lipopeptides recoveries. Further investigations will be devoted to the optimization of the physico-chemical parameters involved in biofilm distribution. [less ▲]

Detailed reference viewed: 16 (9 ULg)
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See detailImplementation of the ALERT algorithm, a new dispatcher-assisted telephone cardiopulmonary resuscitation protocol, in non-Advanced Medical Priority Dispatch System (AMPDS) Emergency Medical Services centres.
STIPULANTE, Samuel ULg; Tubes, Rebecca; Fassi, Mehdi El et al

in Resuscitation (2014), 85(2), 177-181

Objectives: Early bystander cardiopulmonary resuscitation (CPR) is a key factor in improving survival from out-of-hospital cardiac arrest (OHCA). The ALERT (Algorithme Liegeois d'Encadrement a la ... [more ▼]

Objectives: Early bystander cardiopulmonary resuscitation (CPR) is a key factor in improving survival from out-of-hospital cardiac arrest (OHCA). The ALERT (Algorithme Liegeois d'Encadrement a la Reanimation par Telephone) algorithm has the potential to help bystanders initiate CPR. This study evaluates the effectiveness of the implementation of this protocol in a non-Advanced Medical Priority Dispatch System area. Methods: We designed a before and after study based on a 3-month retrospective assessment of victims of OHCA in 2009, before the implementation of the ALERT protocol in Liege emergency medical communication centre (EMCC), and the prospective evaluation of the same 3 months in 2011, immediately after the implementation. Results: At the moment of the call, dispatchers were able to identify 233 OHCA in the first period and 235 in the second. Victims were predominantly male (59%, both periods), with mean ages of 64.1 and 63.9 years, respectively. In 2009, only 9.9% victims benefited from bystander CPR, this increased to 22.5% in 2011 (p<0.0002). The main reasons for protocol under-utilisation were: assistance not offered by the dispatcher (42,3%), caller physically remote from the victim (20.6%). Median time from call to first compression, defined here as no flow time, was 253sec in 2009 and 168sec in 2011 (NS). Ten victims were admitted to hospital after ROSC in 2009 and 13 in 2011 (p=0.09). Conclusion: From the beginning and despite its under-utilisation, the ALERT protocol significantly improved the number of patients in whom bystander CPR was attempted. [less ▲]

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See detailImplementation of the finite element method for non-lambertian indoor surfaces
Embrechts, Jean-Jacques ULg

in Proceedings of the C.I.E. Seminar on Computer Programs for Light and Lighting (1992)

Detailed reference viewed: 13 (5 ULg)
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See detailImplementation of the finite element method for non-lambertian indoor surfaces
Embrechts, Jean-Jacques ULg

in Proceedings of the 7th "Lux Europa" congress (Edinburgh 1993) - Volume 2 (1993)

Detailed reference viewed: 8 (3 ULg)
See detailImplementation of the harmonic balance FEM method for large-scale saturated electromagnetic devices
Driesen, Johan; Deliège, Geoffrey ULg; Van Craenenbroeck, Thierry et al

in Software for Electrical Engineering - Analysis and Design IV (1999)

Detailed reference viewed: 8 (0 ULg)