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See detailThe guidelines on the application of article 81(3) EC: A critical review
Petit, Nicolas ULg

in Working Paper Institut d'Etudes Juridiques Européennes (2009)

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See detailGuidelines on the management of valvular heart disease (version 2012).
Vahanian, Alec; Alfieri, Ottavio; Andreotti, Felicita et al

in European Heart Journal (2012), 33(19), 2451-96

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See detailGuidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS).
Vahanian, Alec; Alfieri, Ottavio; Andreotti, Felicita et al

in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2012), 42(4), 1-44

Detailed reference viewed: 26 (5 ULg)
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See detailGuidelines to Adapt the General Principles of the Non-statistical Meta-analysis Method to Specific Fields of Biomedical Research: the Example of Molecular Oncology.
Pasleau, Françoise ULg; Delvenne, Catherine ULg; Cielniaszek, Nadine

in Libraries without limits : changing needs – changing roles Proceedings of the 6th European Conference of medical and Health Libraries. (1999)

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational ... [more ▼]

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational orientation are responsible for this gap. Effective information management at the institutional level, could provide clinicians the means to adopt new perspectives. At present, the link between basic research and clinical application relies upon the motivation of individuals to develop new skills in literature retrieval and analysis and yet their occupational responsabilities inhibit this endeavour. Academic librarians, educated and trained in information and biomedical sciences, have a role in providing physicians with current and readily applicable knowledge from the critical analysis of the literature. The Faculty of Medicine Library is developing a research programme to design an updated and comprehensive picture of the diagnostic and prognostic biological markers in the field of human prostate cancer. The final product is envisioned as a database accessible on the web that will integrate bibliographic analyses and results from prospective and retrospective studies conducted at the University of Liège. As this product is designed to have a direct impact on clinical decision making and patient care, it should guarantee thoroughness, relevancy and objectivity and not become yet another narrative review of the literature. Over the last decade, there has been a movement towards using statistical meta-analyses to synthesize literature. This method has proven to be useful when similar strategies are used to produce similar quantitative outcomes that can be merged for statistical analysis.1 Even though studies in cancer research assess the same model, they are often too fragmented or heterogeneous in their design, methods and instrumentation. Approaches have been developed to conduct non-statistical meta-analysis of such publications.2 Quantitative and qualitative meta-analyses are based on common principles which are largely discussed in the literature. They are related to model development, literature coding, rating references for quality and annotating and synthesizing high quality references. In practice, these basic principles require translation into actual instructions adapted to every domain of biomedical research. Variable definition is a very critical step that governs the quality of subsequent analyses. Specific examples provided illustrate the guidelines acquired from our experience. Il s'écoule souvent un intervalle de temps fort long avant que les nouveaux concepts issus de la recherche biomédicale soient intégrés dans la pratique médicale courante. Les raisons de cette situation sont autant d'ordre économique et technique que culturel. Actuellement, les liens entre la recherche fondamentale et la médecine clinique ne peuvent exister que sur base d'initiatives individuelles et les médecins concernés doivent investir une partie de leur temps dans l'apprentissage des techniques de recherche et d'analyse de la littérature. Une gestion professionnelle de l'information au niveau d'une institution telle qu'un hôpital universitaire devrait par contre inciter davantage de cliniciens à utiliser les ressources de la littérature issue de la recherche biomédicale. C'est pourquoi la Bibliothèque de la Faculté de Médecine de l'Université de Liège propose, à titre expérimental, de créer un prototype de site web consacré à l'étude des marqueurs pronostiques et diagnostiques du cancer de la prostate. Des scientifiques, spécialisés en sciences biomédicales et formés aux techniques de gestion documentaire, fourniront à l'intention des médecins spécialistes et/ou généralistes, voire des patients eux-mêmes, une analyse critique de la littérature en relation directe avec les activités cliniques de l'institution. Notre objectif étant de fournir aux médecins des informations susceptibles d'être utilisées comme bases de décision clinique, notre responsabilité se trouve engagée vis à vis des patients. Nous devrons donc définir une stratégie qui garantisse à la fois l'exhaustivité et la pertinence de l'information traitée et l'objectivité des analyses présentées. Sur base des principes de la méta-analyse,1,2 nous avons conçu un protocole en cinq étapes comprenant: la définition à priori des objectifs, la recherche non biaisée d'information, la définition de critères de sélection des études, l'extraction et la synthèse des données. La difficulté consistera à traduire ces principes en une série de consignes pratiques et techniques et d'en dégager des lignes de conduite générales qui permettront d'étendre cette approche à n'importe quel domaine de la médecine. 1. D'Agostino RB, Weintraub M. Meta-analysis: a method for synthesizing research. Clin Pharmacol Ther 1995;58:605-616 2. Bland CJ, Meurer LN, Maldonado G. A systematic approach to conducting a non-statistical meta-analysis of research literature. Acad Med 1995;70:642-653 [less ▲]

Detailed reference viewed: 37 (0 ULg)
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See detailGuidelines to Adapt the General Principles of the Non-statistical Meta-analysis Method to Specific Fields of Biomedical Research: the Example of Molecular Oncology.
Pasleau, Françoise ULg; Delvenne, Catherine ULg; Cielnaszek, Nadine

Conference (1998, June 26)

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational ... [more ▼]

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational orientation are responsible for this gap. Effective information management at the institutional level, could provide clinicians the means to adopt new perspectives. At present, the link between basic research and clinical application relies upon the motivation of individuals to develop new skills in literature retrieval and analysis and yet their occupational responsabilities inhibit this endeavour. Academic librarians, educated and trained in information and biomedical sciences, have a role in providing physicians with current and readily applicable knowledge from the critical analysis of the literature. The Faculty of Medicine Library is developing a research programme to design an updated and comprehensive picture of the diagnostic and prognostic biological markers in the field of human prostate cancer. The final product is envisioned as a database accessible on the web that will integrate bibliographic analyses and results from prospective and retrospective studies conducted at the University of Liège. As this product is designed to have a direct impact on clinical decision making and patient care, it should guarantee thoroughness, relevancy and objectivity and not become yet another narrative review of the literature. Over the last decade, there has been a movement towards using statistical meta-analyses to synthesize literature. This method has proven to be useful when similar strategies are used to produce similar quantitative outcomes that can be merged for statistical analysis.1 Even though studies in cancer research assess the same model, they are often too fragmented or heterogeneous in their design, methods and instrumentation. Approaches have been developed to conduct non-statistical meta-analysis of such publications.2 Quantitative and qualitative meta-analyses are based on common principles which are largely discussed in the literature. They are related to model development, literature coding, rating references for quality and annotating and synthesizing high quality references. In practice, these basic principles require translation into actual instructions adapted to every domain of biomedical research. Variable definition is a very critical step that governs the quality of subsequent analyses. Specific examples provided illustrate the guidelines acquired from our experience. 1. D'Agostino RB, Weintraub M. Meta-analysis: a method for synthesizing research. Clin Pharmacol Ther 1995;58:605-616 2. Bland CJ, Meurer LN, Maldonado G. A systematic approach to conducting a non-statistical meta-analysis of research literature. Acad Med 1995;70:642-653 [less ▲]

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See detailGuides d'architecture moderne et contemporaine en Wallonie et à Bruxelles
Charlier, Sébastien ULg; Moor, Thomas

Conference (2014, November 25)

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See detailGuillain-Barré syndrome following hepatitis E
Loly, Jean-Philippe ULg; Rikir, Estelle ULg; Seivert, Maxime ULg et al

in World Journal of Gastroenterology (2009), 15(13), 1645-1647

Guillain-Barré syndrome (GBS) is often triggered by a preceding bacterial or viral infection. Occasionally, it has been observed in association with acute hepatitis A, B and C, and three cases have been ... [more ▼]

Guillain-Barré syndrome (GBS) is often triggered by a preceding bacterial or viral infection. Occasionally, it has been observed in association with acute hepatitis A, B and C, and three cases have been previously described in India in which GBS was associated with acute hepatitis E. A molecular mimicry mechanism is supposed to be involved in the pathogenesis of GBS triggered by infectious agents, although the nature of the shared epitopes has not been characterized in most instances, including that in the case of hepatotropic viruses. We report a case of GBS following acute hepatitis E in a European individual. The presence of antiganglioside GM2 antibodies in this patient suggested molecular mimicry involving ganglioside GM2 in the pathogenesis of GBS associated with hepatitis E. [less ▲]

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See detailGuillaume de Savoie. Un monstrum spirituale et belua multorum capitum sur le trône de saint Lambert ?
Marchandisse, Alain ULg

in Bulletin de la Société Royale Le Vieux-Liège (1997), 13

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See detailGuillaume le Blanc, la dislocation de la voix des précaires
Herla, Anne ULg

in Jeanmart, Gaëlle (Ed.) Mépris et reconnaissance sociale. Donner une voix à ceux dont la parole ne compte pas. (2011)

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See detailGuilt and Responsibility in Restorative Justice and Criminal Justice
Lauwaert, Katrien ULg

Conference (2009, September)

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See detailGuinea fowl rearing constraints and flock composition under traditional management in Borgou Department, Benin
Dahouda, Mahamadou; Toléba, Seibou Soumanou; Youssao, A. K. I. et al

in Family Poultry (2007), 17(1&2), 3-14

A survey was conducted in Borgou department (northern Benin) to characterize Guinea fowl production systems in rural areas. A questionnaire was administered to 70 Guinea fowl keepers in order to collect ... [more ▼]

A survey was conducted in Borgou department (northern Benin) to characterize Guinea fowl production systems in rural areas. A questionnaire was administered to 70 Guinea fowl keepers in order to collect information about Guinea fowl management and husbandry practices in the region. This activity was practised according to traditional management in Benin where free range is the most common system of rearing. Birds scavenged during the day while at night, keets and surrogate hens were housed in poor, cramped coops whereas adult Guinea fowls roosted on trees. No rational feeding system was practised. Guinea fowls gleaned grass seeds, vegetable leaves, insects, worms, bones and eggshells. Poultry received a supplement consisting of cereals and their by-products, e.g. sorghum (30.4%), maize (25.0%), rice (14.3%), maize bran (7.1%), kitchen waste (5.4%), sorghum bran (3.6%), millet (1.8%) and complete food (1.8%). Adult body weight was 1121.3±100.2g at 6 months and maximum growth rate of 10.2g/day was reached at four months. Point-of-lay was between 7 and 9 months. Local hens were used to incubate Guinea fowl eggs, and hatchability was 72.9%. The survey revealed that Guinea fowl productivity is low because of high keet mortality. Average keet mortality registered from 0 to 6 months was 48% (range 3 to 100%). Moreover, 74% of interviewed farmers reported that keet mortality constituted the major constraint to Guinea fowl rearing. Others reported constraints, included keet weakness, poor quality of eggs, egg losses hidden under brush, keets predation, poor housing and infestations. The size of the keet populations varied over the year with the highest proportion in June-July while the proportion of growers increased from September to January. [less ▲]

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See detailGunflint microbiota
Javaux, Emmanuelle ULg

in Gargaud, Muriel; Pinti, Daniele; Amils, Ricardo (Eds.) et al Encyclopedia of Astrobiology (2011)

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See detailGürtel der hl. Madalberta aus Lüttich Spätmittelalterlich
George, Philippe ULg

in Catalogue de l’exposition Krone und Scheller. Kunst aus Mittelalterlichen Frauenklöstern, Essen, 2005, p. 277-8. (2005)

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See detailGus Van Sant. Le cinéma en bohème
Tomasovic, Dick ULg

Conference given outside the academic context (2012)

Detailed reference viewed: 30 (4 ULg)
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See detailGust Loads
Dimitriadis, Grigorios ULg

in Multiple (Ed.) Design Loads for Future Aircraft (2002)

The selection of design loads and requirements is defining the structural weight of airplanes and their safety. Therefore the definition of requirements should be performed very critically by the customer ... [more ▼]

The selection of design loads and requirements is defining the structural weight of airplanes and their safety. Therefore the definition of requirements should be performed very critically by the customer and structural weight should be assessed based on sensitivity analysis of the total aircraft which includes flight manoeuvre simulation, flight control system, aerodynamics and elastic effects introduced by finite elements. To produce these analyses is the job of the aircraft companies. After selection of most load critical flight manoeuvres (pull up manoeuvres, initiation of roll manoeuvres etc.) the calculation of airloads and inertia loads must include the flight control system and its failure cases because it affects the motion of the control surfaces and therefore the aircraft. With the advent of carbon fibre composite structures discrete loads are the predominant limiting design conditions but it should be emphasised that most structures are of a hybrid nature with metal frame which are still susceptible to fatigue loads. For airplanes designed to civil requirements such as transport airplanes, tankers etc. the definition of continuous turbulence and inclusion of FCS failure cases and nonlinearities such as control surface angles is extremely important. There was a long way from load assumptions used by the Wright Brothers who designed their Flyer to a 5g limit to the load limiting capabilities of the care free handling flight control system of the Eurofighter. Also the US-Airforce Mil-Specifications which were used to design NATO airplanes such as Tornado, F16 and F18 in the 1970’s are obsolete today and the MIL-A-87221 (USAF) is only a frame without the essential quantitative material. All these issues are addressed in this manual including comparisons of regulations and descriptions of new specifications. Complete procedures how to establish design loads are presented which should help for the design of new airplanes. The importance of dynamic phenomena which produce design loads for various aircraft parts such as intakes, leading edges etc. is also highlighted. Loads monitoring systems are necessary to prove calculated loads and monitor fatigue loads to establish the remaining structural life. There is a description of a modern system. For transport type aircraft gust load cases are the most critical for strength design and they are also the main fatigue loading source for the major part of the structure. Methods for discrete and continuous gust loading cases are presented together with nonlinear example calculations. In the appendix there is a description of failure cases and their effect on loads for transport aircraft and a specification of a landing gear which could be used as an example how to specify the whole structure as a system. The military use of this manual is to establish procedures to build the lightest structure for the military requirements. Agreement on requirements and design loads within the NATO countries could standardise pilot training, aircraft usage, increase aircraft life and reduce maintenance. Since the search of the best usage of the aircraft for its military purpose will continue to integrate structure and avionics such as fire and flight control systems as an example there will be a continuous need for future work. [less ▲]

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