Macros Minitab pour l'analyse des séries chronologiques par décomposition

Software (2008)

Macros Minitab pour l'estimation de paramètres à partir de résultats d'enquêtes

Software (2003)

Macros Minitab pour la définition du plan d'échantillonnage à la réception dans le cas de mesures.

Software (2003)

Macros Minitab pour la détermination par Bootstrap des limites de confiance d'un estimateur

Software (2002)

Macros Minitab pour le calcul des courbes d'efficacité des cartes de contrôle Shewhart.

Software (2003)

Macros Minitab pour le choix d'une transformation pour la normalisation d'une variable

Software (2011)

Macroscale ecohydrodynamic modeling on the Northwest European Continental Shelf

in Journal of Marine Systems (1998), 16(1-2), 171-190

A 3D coupled hydrodynamic-biological model is applied to the simulation of the biological processes on the Northwest European Continental Shelf. The model operates in the macroscale spectral window (time ... [more ▼]

A 3D coupled hydrodynamic-biological model is applied to the simulation of the biological processes on the Northwest European Continental Shelf. The model operates in the macroscale spectral window (time scales of a month or a season) without explicit description of the higher frequency processes but with an adequate modeling of their influence on larger time scales. The hydrodynamic sub-model is 3D, baroclinic and includes a refined turbulence closure. The non-linear interactions of mesoscale fluctuations are described by means of the generalized mesoscale Reynolds stresses and the Stokes drift transport velocity field. The biological sub-model describes the nitrogen and carbon cycles through the food web with 17 state variables representing 9 compartments: inorganic nutrients, small phytoplankton, large phytoplankton, dissolved organic matter, pelagic bacteria, heterotrophic flagellates, pelagic detritus, zooplankton and benthic organic detritus. The simulation emphasizes the strong influence of the local depth and of the stability of the water column on the whole annual cycle of phytoplankton. In well-mixed shallow areas, the chlorophyll concentration increases in early spring and the primary production occurs steadily until October. In deeper areas, the spring bloom is much sharper and appears later, after the set up of the seasonal stratification. The main part of the primary production happens during the bloom period. The macroscale approach provides results that are comparable with observations and results of other more classical models describing explicitly the higher frequency processes. The current method allows, however, a more direct insight into the dynamics of the system and into the interactions between the hydrodynamics and the biology. Also, it greatly reduces the CPU requirements and is therefore particularly suited for repeated or long term simulations. (C) 1998 Elsevier Science B.V. All rights reserved. [less ▲]

Madame Bovary, celle que l'on n'attendait pas.

Conference given outside the academic context (2012)

Madeleine Bourdouxhe, la pudeur et l'ellipse

in Kovacshazy, Cécile (Ed.) Relire Madeleine Bourdouxhe. Regards croisés sur son oeuvre littéraire (2012)

La modernité de Madeleine Bourdouxhe passe par des figures de la narration, comme la métalipse et ce que l'on se propose d'appeler ici "figure Stendhal" et "figure Flaubert".

Madin Darby Bovine Kidney Cell Synchronization by Lovastatin: Application to Bovine Herpesvirus-1 Gene Expression

in Veterinary Research (1994), 25(6), 555-67

The number of investigations involving cell proliferation has increased rapidly in the last years. One of the major difficulties in studying cell-cycle-related events is obtaining highly synchronous cell ... [more ▼]

The number of investigations involving cell proliferation has increased rapidly in the last years. One of the major difficulties in studying cell-cycle-related events is obtaining highly synchronous cell populations without metabolic imbalance. This study demonstrates that the Madin Darby bovine kidney (MDBK) cells, a commonly used cell line in veterinary research, can be effectively synchronized using lovastatin (Lov), a drug used to treat hypercholesteremia in humans. This was demonstrated by the following results: (i) Lov inhibits cell proliferation in a dose-dependent manner; (ii) Lov synchronizes MDBK cells mainly in the G1 and secondarily in the G2+M cell-cycle phases; (iii) the cytostatic effect of Lov can be specifically inhibited by addition of mevalonate (Mev) (Lov inhibits the synthesis of Mev); (iv) removal of Lov from G1-arrested cultures, followed by addition of Mev, resulted in the synchronous recovery of DNA synthesis; and (v) 5-bromo2'-deoxyuridine incorporation experiments revealed that MDBK cells synchronization by Lov can be followed for at least 3 cycles after removal of Lov and addition of Mev. Furthermore, as an application of investigations based on the availability of synchronized MDBK, we showed that bovine herpesvirus-1 gene expression is independent on the cell cycle. [less ▲]