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Showing results 52641 to 52660 of 96293
  Leopold August Warnkönig, een voorganger van François Laurent in de universiteiten van Luik en GentGerkens, Jean-François  Scientific conference (2013, April 24) Detailed reference viewed: 4 (0 ULg)Leopold II en zijn koloniale doctrine: van de hertog van Brabant tot 1885.Vandersmissen, Jan in Dujardin, Vincent; Planche, Stéphanie; Plasman, Pierre-Luc (Eds.) et al Leopold II, ongegeneerd genie? Buitenlandse politiek en kolonisatie. (2009) Detailed reference viewed: 20 (2 ULg)Léopold II et sa doctrine coloniale: du duc de Brabant à 1885Vandersmissen, Jan in Dujardin, Vincent; Rosoux, Valérie; de Wilde d'Estmael, Tanguy (Eds.) et al Léopold II. Entre génie et gêne. politique étrangère et colonisation. (2009) Detailed reference viewed: 33 (3 ULg)Léopold II, un roi déterminé face à la guerre franco-allemande de 1870.Raxhon, Philippe in Dujardin, Vincent; Rosoux, Valérie; de Wilde, Tanguy (Eds.) Léopold II. Entre génie et gêne. Politique étrangère et colonisation. (2009) Detailed reference viewed: 18 (0 ULg) Leptin Effects on Pulsatile Gonadotropin Releasing Hormone Secretion from the Adult Rat Hypothalamus and Interaction with Cocaine and Amphetamine Regulated Transcript Peptide and Neuropeptide YParent, Anne-Simone ; ; Gerard, Arlette et alin Regulatory Peptides (2000), 92(1-3), 17-24 Leptin may act as a negative feedback signal to the hypothalamic control of appetite through suppression of neuropeptide Y (NPY) secretion and stimulation of cocaine and amphetamine regulated transcript ... [more ▼] Leptin may act as a negative feedback signal to the hypothalamic control of appetite through suppression of neuropeptide Y (NPY) secretion and stimulation of cocaine and amphetamine regulated transcript (CART). We aimed at studying the effects of leptin, CART and NPY on the hypothalamic control of the pituitary-gonadal system. Pulsatile gonadotropin-releasing hormone (GnRH) secretion was studied in vitro using retrochiasmatic hypothalamic explants from adult rats. In the female, GnRH pulse amplitude was significantly increased by leptin (10(-7) M) and CART (10(-6) M) irrespective of the estrus cycle phase while no such effects were seen in the male. The GnRH interpulse interval was not affected in both sexes. Passive immunoneutralization against CART caused a reduction in GnRH pulse amplitude in the female. A slight but significant increase in GnRH pulse amplitude was caused by NPY (10(-7) M) in the female. However, GnRH pulse amplitude was not affected by a Y5-receptor antagonist (10(-6) M) while the interpulse interval was significantly increased as shown previously in the male. The increase in GnRH pulse amplitude caused by leptin was totally prevented by coincubation with an anti-CART antiserum whereas it was not affected by coincubation with the NPY Y5-receptor antagonist (10(-7) M). In conclusion, leptin and NPY show separate permissive effects on GnRH secretion in the adult rat hypothalamus. In both sexes, NPY is prominently involved in the control of the frequency of pulsatile GnRH secretion through the Y5 receptor subtype. Leptin causes a female-specific facilitatory effect on GnRH pulse amplitude which is mediated by CART and which occurs irrespective of the estrus cycle phase. [less ▲] Detailed reference viewed: 18 (1 ULg)Leptin Reverts Pro-Apoptotic and Antiproliferative Effects of α-Linolenic Acids in BCR-ABL Positive Leukemic Cells: Involvement of PI3K PathwayBeaulieu, Aurore ; Poncin, Géraldine ; et alin PLoS ONE (2011), 6(10), 25651 It is suspected that bone marrow (BM) microenvironmental factors may influence the evolution of chronic myeloid leukaemia (CML). In this study, we postulated that adipocytes and lipids could be involved ... [more ▼] It is suspected that bone marrow (BM) microenvironmental factors may influence the evolution of chronic myeloid leukaemia (CML). In this study, we postulated that adipocytes and lipids could be involved in the progression of CML. To test this hypothesis, adipocytes were co-cultured with two BCR-ABL positive cell lines (PCMDS and K562). T cell (Jurkat) and stroma cell (HS-5) lines were used as controls. In the second set of experiments, leukemic cell lines were treated with stearic, oleic, linoleic or α-linolenic acids in presence or absence of leptin. Survival, proliferation, leptin production, OB-R isoforms (OB-Ra and OB-Rb), phosphoinositide 3-kinase (PI3k) and BCL-2 expression have been tested after 24h, 48h and 72h of treatment. Our results showed that adipocytes induced a decrease of CML proliferation and an increase in lipid accumulation in leukemic cells. In addition, CML cell lines induced adipocytes cell death. Chromatography analysis showed that BM microenvironment cells were full of saturated (SFA) and monounsaturated (MUFA) fatty acids, fatty acids that protect tumor cells against external agents. Stearic acid increased Bcl-2 expression in PCMDS, whereas oleic and linoleic acids had no effects. In contrast, α-linolenic acid decreased the proliferation and the survival of CML cell lines as well as BCL-2 and OB-R expression. The effect of α-linolenic acids seemed to be due to PI3K pathway and Bcl-2 inhibition. Leptin production was detected in the co-culture medium. In the presence of leptin, the effect of α-linolenic acid on proliferation, survival, OB-R and BCl-2 expression was reduced.</p> [less ▲] Detailed reference viewed: 30 (12 ULg)La leptine et les hormones métaboliques chez trois races de bovins viandeuxPirotte, Cécile ; ; Cabaraux, Jean-François et alin 10èmes Rencontres autour des Recherches sur les Ruminants (2003) Detailed reference viewed: 8 (0 ULg)Leptogenesis in flavor models with type I and II seesawsAristizabal Sierra, Diego ; ; in Nuclear Physics B (2012) In type I seesaw models with flavor symmetries accounting for the lepton mixing angles the CP asymmetry in right-handed neutrino decays vanishes in the limit in which the mixing pattern is exact. We study ... [more ▼] In type I seesaw models with flavor symmetries accounting for the lepton mixing angles the CP asymmetry in right-handed neutrino decays vanishes in the limit in which the mixing pattern is exact. We study the implications that additional degrees of freedom from type II seesaw may have for leptogenesis in such a limit. We classify in a model independent way the possible realizations of type I and II seesaw schemes, differentiating between classes in which leptogenesis is viable or not. We point out that even with the interplay of type I and II seesaws there are generic classes of minimal models in which the CP asymmetry vanishes. Finally we analyze the generation of the lepton asymmetry by solving the corresponding kinetic equations in the general case of a mild hierarchy between the light right-handed neutrino and the scalar triplet masses. We identify the possible scenarios in which leptogenesis can take place. [less ▲] Detailed reference viewed: 10 (4 ULg)Leptogenesis in the presence of exact flavor symmetriesAristizabal Sierra, Diego ; in Journal of High Energy Physics [=JHEP] (2012) In models with flavor symmetries in the leptonic sector leptogenesis can take place in a very different way compared to the standard leptogenesis scenario. We study the generation of a B−L asymmetry in ... [more ▼] In models with flavor symmetries in the leptonic sector leptogenesis can take place in a very different way compared to the standard leptogenesis scenario. We study the generation of a B−L asymmetry in these kind of models in the flavor symmetric phase pointing out that successful leptogenesis requires (i) the right-handed neutrinos to lie in different irreducible representations of the flavor group; (ii) the flavons to be lighter at least that one of the right-handed neutrino representations. When these conditions are satisfied leptogenesis proceeds due to new contributions to the CP violating asymmetry and — depending on the specific model — in several stages. We demonstrate the validity of these arguments by studying in detail the generation of the B − L asymmetry in a scenario of a concrete A 4 flavor model realization. [less ▲] Detailed reference viewed: 7 (2 ULg)Lepton flavor violation and seesaw symmetriesAristizabal Sierra, Diego in Hyperfine Interactions (in press) When the standard model is extended with right-handed neutrinos the symmetries of the resulting Lagrangian are enlarged with a new global U(1)R Abelian factor. In the context of minimal seesaw models we ... [more ▼] When the standard model is extended with right-handed neutrinos the symmetries of the resulting Lagrangian are enlarged with a new global U(1)R Abelian factor. In the context of minimal seesaw models we analyze the implications of a slightly broken U(1)R symmetry on charged lepton flavor violating decays. We find, depending on the R-charge assignments, models where charged lepton flavor violating rates can be within measurable ranges. In particular, we show that in the resulting models due to the structure of the light neutrino mass matrix muon flavor violating decays are entirely determined by neutrino data (up to a normalization factor) and can be sizable in a wide right-handed neutrino mass range. [less ▲] Detailed reference viewed: 15 (5 ULg)Leptospira spp. prevalence in small mammal populations in Cotonou, BeninHouemenou, Gualbert ; ; Libois, Roland et alin ISRN Epidemiology (2013) The aim of this study was to assess the Leptospira prevalence in small animals in Cotonou, the capital of Benin. Rodents and shrews were captured in urban and periurban settings and determined as species ... [more ▼] The aim of this study was to assess the Leptospira prevalence in small animals in Cotonou, the capital of Benin. Rodents and shrews were captured in urban and periurban settings and determined as species of the genera Rattus, Mastomys, and Crocidura. Kidney specimens of 90 animals were examined using a real-time PCR assay specific for leptospires that belong to pathogenic species. Leptospiral DNA was amplified from kidney tissues ranging from 13.3% (8/60) in Rattus rattus to 100.0% (1/1) in Crocidura spp. with an average of 18.9% (17/90) of the animals caught at 15 locations. Clade-specific Taqman PCR on 10 samples placed six of these within clade 1 comprising the species L. kirschneri, L. interrogans, L. meyeri, and L. noguchii and four within clade 2 consisting of species L. weilii, L. alexanderi, L. borgpetersenii, and L. santarosai. Phylogenetic analysis of partial sequences of the amplicons of seven samples of these 10 samples revealed that four of the clade 1 samples could equally be assigned to L. interrogans and L. kirschneri and three samples fromclade 2 belonged to L. borgpetersenii. Results presented in the paper indicate that small mammals present a major public health risk for acquiring leptospirosis in Cotonou, Benin and will contribute to a raised awareness amongst health care workers and decision makers and hence promote appropriate clinical management of cases. [less ▲] Detailed reference viewed: 32 (3 ULg)Lernen lebender Fremdsprachen an den Schulen der europaïschen UnionBlondin, Christiane Book published by Amt für amtliche Veröffentlichungen der Europaïschen Gemeinschaften (1997) Detailed reference viewed: 3 (0 ULg)Lernout & Hauspie, Neuroplanet, SABENA ... ou quand les rêves indomptés s’écrasent contre les murs de la réalitéVan Caillie, Didier Article for general public (2002) This chronicle analyses the reasons for some important recent firm failures in Belgium and insists on the crucial role played by growth management in the evolution of the firm Detailed reference viewed: 24 (2 ULg)Le lérot: Eliomys quercinusLibois, Roland Learning material (1994) Detailed reference viewed: 7 (0 ULg)Le lérot: trois études en une enquêteLibois, Roland Learning material (2003) Detailed reference viewed: 8 (0 ULg) Les 70 ans de la mort de Stefan Zweig. Sous une forme esthétisante, se dissimulait un personnage complexe. Interview avec Achim KüpperKüpper, Achim ; E-print/Working paper (2012) Detailed reference viewed: 5 (0 ULg)Les activités d’extraction et la zone d’extraction (ZE). In: Evaluation des besoins et des activités. Problématique de leur localisation; ; Halleux, Jean-Marie Report (2002) Detailed reference viewed: 2 (1 ULg)Les adénomes hypophysaires : du diagnostic au traitement en passant par la contraception, la grossesse et la ménopauseBeckers, Albert Scientific conference (2013, January) Detailed reference viewed: 20 (4 ULg)Les adénomes hypophysaires à TSH.Beckers, Albert ; Stevenaert, Achille in Revue Française d'Endocrinologie Clinique, Nutrition, et Métabolisme (La) (1992), 33(2), 151-156 Detailed reference viewed: 2 (0 ULg)Les Adénomes somatotropes: Facteurs prédictifs de rémission en analyse multivariée après chirurgie transphenoidaleVALDES SOCIN, Hernan Gonzalo Master of advanced studies dissertation (1999) Detailed reference viewed: 22 (6 ULg) |
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