Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailImagination, religion et réforme intellectuelle chez Hobbes
Herla, Anne ULg

in Terrel, Jean; Graciannette, Bernard (Eds.) Hobbes et la religion (2012)

Detailed reference viewed: 18 (2 ULg)
Full Text
Peer Reviewed
See detailImagine imaging neural activity in crying infants and in their caring parents
Laureys, Steven ULg; Goldman, S.

in Behavioral and Brain Sciences (2004), 27(4), 465

Soltis' paper contains little data on the underlying neural substrate of the discussed signal function of early infant crying-probably because there is amazingly little known about it. We here discuss the ... [more ▼]

Soltis' paper contains little data on the underlying neural substrate of the discussed signal function of early infant crying-probably because there is amazingly little known about it. We here discuss the interest of functional neuroimaging as an objective measurement of brain activity in (1) early infants during crying and (2) parents hearing their offspring cry. [less ▲]

Detailed reference viewed: 17 (1 ULg)
See detailImaginer l’indicible. De l’influence mutuelle entre textes et images dans l’œuvre des hagiographes et des mystiques médiévaux (VIIe-XIIe)
Close, Florence ULg

Conference (2011, May 11)

Cette communication consistait en une réflexion sur les tentatives d’imagination de la Trinité divine, dogme fondamental du christianisme. Elle portait plus particulièrement sur la manière dont les clercs ... [more ▼]

Cette communication consistait en une réflexion sur les tentatives d’imagination de la Trinité divine, dogme fondamental du christianisme. Elle portait plus particulièrement sur la manière dont les clercs et les moines du haut moyen âge et du moyen âge central ont perçu, le temps d’une expérience mystique extraordinaire, les relations unissant les trois personnes divines entre elles. L'auteur pose la question du rôle et de l’importance des représentations mentales et de la traduction picturale de certains détails et mouvements – énoncés ou non dans les traités théologiques, la tradition scripturaire ou les textes liturgiques – dans le processus de compréhension et d’appréhension de ce mystère. Elle n'hésite pas à confronter des images perçues par les visionnaires aux images de la Trinité produites à la même époque (Trône de grâce, Trinité du psautier, Trinité triandrique, Trinité tricéphale/trifrons, Paternité, Trinité à deux médaillons). [less ▲]

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailImaginer l’indicible. De la mise en mouvement des images dans les récits de visions de la Trinité des hagiographes et des mystiques médiévaux (VIIe-XIIe siècles)
Close, Florence ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

Cette communication consistait en une réflexion sur les tentatives d’imagination de la Trinité divine, dogme fondamental du christianisme. Elle portait plus particulièrement sur la manière dont les clercs ... [more ▼]

Cette communication consistait en une réflexion sur les tentatives d’imagination de la Trinité divine, dogme fondamental du christianisme. Elle portait plus particulièrement sur la manière dont les clercs et les moines du haut moyen âge et du moyen âge central ont perçu, le temps d’une expérience mystique extraordinaire, les relations unissant les trois personnes divines entre elles. L'auteur pose la question du rôle et de l’importance des représentations mentales et de la traduction picturale de certains détails et mouvements – énoncés ou non dans les traités théologiques, la tradition scripturaire ou les textes liturgiques – dans le processus de compréhension et d’appréhension de ce mystère. Elle n'hésite pas à confronter des images perçues par les visionnaires aux images de la Trinité produites à la même époque (Trône de grâce, Trinité du psautier, Trinité triandrique, Trinité tricéphale/trifrons, Paternité, Trinité à deux médaillons). [less ▲]

Detailed reference viewed: 27 (4 ULg)
Full Text
See detailImaginer-lire Le Capital. Approche des Nachrichten aus der ideologischen Antike
Pieron, Julien ULg

Conference (2013, December 13)

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailImaging a cognitive model of apraxia: The neural substrate of gesture-specific cognitive processes
Peigneux, Philippe ULg; Van der Linden, Martial ULg; Garraux, Gaëtan ULg et al

in Human Brain Mapping (2004), 21(3), 119-142

The present study aimed to ascertain the neuroanatomical basis of an influential neuropsychological model for upper limb apraxia [Rothi LJ, et al. The Neuropsychology of Action. 1997. Hove, UK: Psychology ... [more ▼]

The present study aimed to ascertain the neuroanatomical basis of an influential neuropsychological model for upper limb apraxia [Rothi LJ, et al. The Neuropsychology of Action. 1997. Hove, UK: Psychology Press]. Regional cerebral blood flow was measured in healthy volunteers using (H2O)-O-15 PET during performance of four tasks commonly used for testing upper limb apraxia, i.e., pantomime of familiar gestures on verbal command, imitation of familiar gestures, imitation of novel gestures, and an action-semantic task that consisted in matching objects for functional use. We also re-analysed data from a previous PET study in which we investigated the neural basis. of the visual analysis of gestures. First; we found that two sets of discrete brain areas are predominantly engaged in the imitation of familiar and novel gestures, respectively. Segregated brain activation for novel gesture mutation concur with neuropsychological reports to support the hypothesis that knowledge about the organization of the human body mediates the transition from visual perception to motor execution when imitating novel gestures [Goldenberg Neuropsychologia 1995;35.63-72]. Second, conjunction analyses revealed distinctive neural bases for most of the gesture-specific cognitive processes proposed in this cognitive model of upper limb apraxia. However, a functional analysis of brain imaging data suggested that one single memory store may be used for "to be-perceived" and "to-be-produced" gestural representations, departing from Rothi et al.'s proposal. Based on the above considerations, we suggest and discuss a revised model for upper limb apraxia that might best account for both brain imaging findings and neuropsychological dissociations reported in the apraxia literature. (C) 2004 Wiley-Liss, Inc. [less ▲]

Detailed reference viewed: 72 (4 ULg)
See detailImaging and in Situ Particle Observations of Particles Accelerated by Auroral Electric Fields
Mende, S. B.; Carlson, C. W.; Frey, H. U. et al

Conference (2002, May 01)

Images from the IMAGE Wide-band Imaging Camera (WIC) and Spectrographic Imager (SI) channels SI12 and SI13, were compared to in situ data taken by FAST for several cases of substorm onsets and following ... [more ▼]

Images from the IMAGE Wide-band Imaging Camera (WIC) and Spectrographic Imager (SI) channels SI12 and SI13, were compared to in situ data taken by FAST for several cases of substorm onsets and following auroral conditions. FAST spacecraft observations had shown that the high latitude auroral ionosphere has several distinct regions and two of those are associated with intense particle precipitation The upward current region contains converging electric field structures, large-scale density cavities, down-going inverted V electrons and quasi-static potential structures. Another, sometimes distinct, region is characterized by filamentary currents containing Alfvenic electric fields, field aligned counter streaming (superthermal) electrons and ion heating transverse to B with associated large ion outflow. In two of the cases presented the satellite passed through the substorm surge on its duskward flank fairly soon after substorm onset. In these cases the superthermal wave accelerated component was clearly found to be on the polar cap boundary of the surge and could be isolated from inverted V precipitation which occurred in the more equatorward parts of the auroral oval. It is suggested that the wave accelerated precipitation is the signature of intense earthward-directed, Alfvenic Poynting fluxes usually observed at altitudes of 4-6 Re near the lobe/plasma sheet interface. In one of the cases the surge was accompanied by intense ion outflow. In three of the cases presented FAST passed through the substorm aurora at midnight or the dawn side outside of the surge and the wave accelerated electrons were less clearly separated from the inverted V type precipitation and the wave accelerated, electrons were seen to be part of very short lived transient events i.e. bursts. The ions were present equatorward of the surge with no enhancement poleward of their normal auroral oval position. The region of auroral forms, associated with intense Alfven waves propagating from the magnetosphere, are most likely to be produced by rapidly moving field lines through (substorm) dynamic reconfiguration unlike inverted V type electric field structures which may be produced by steady plasma convection. The ability to image the two different types of auroras would allow to map the field lines connected to regions of dynamic field configuration. [less ▲]

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailImaging apolipoprotein AI in vivo
Sriram, Renuka; Lagerstedt, Jens; Petrlova, Jitka et al

in NMR in Biomedicine (2011), 24(7), 916-924

Coronary disease risk increases inversely with high-d. lipoprotein (HDL) level. The measurement of the biodistribution and clearance of HDL in vivo, however, has posed a tech. challenge. This study ... [more ▼]

Coronary disease risk increases inversely with high-d. lipoprotein (HDL) level. The measurement of the biodistribution and clearance of HDL in vivo, however, has posed a tech. challenge. This study presents an approach to the development of a lipoprotein MRI agent by linking gadolinium methanethiosulfonate (Gd[MTS-ADO3A]) to a selective cysteine mutation in position 55 of apo AI, the major protein of HDL. The contrast agent targets both liver and kidney, the sites of HDL catabolism, whereas the std. MRI contrast agent, gadolinium-diethylenetriaminepentaacetic acidbismethylamide (GdDTPA-BMA, gadodiamide), enhances only the kidney image. Using a modified apolipoprotein AI to create an HDL contrast agent provides a new approach to investigate HDL biodistribution, metab. and regulation in vivo. [less ▲]

Detailed reference viewed: 13 (3 ULg)
Full Text
Peer Reviewed
See detailImaging artificial salt water infiltration using electrical resistivity tomography constrained by geostatistical data
Hermans, Thomas ULg; Vandenbohede, Alexander; Lebbe, Luc et al

in Journal of Hydrology (2012), 438-439

Electrical resistivity tomography is a well-known technique to monitor fresh-salt water transitions. In such environments, boreholes are often used to validate geophysical results but rarely used to ... [more ▼]

Electrical resistivity tomography is a well-known technique to monitor fresh-salt water transitions. In such environments, boreholes are often used to validate geophysical results but rarely used to constrain the geoelectrical inversion. To estimate the extent of salt water infiltration in the dune area of a Natural Reserve (Westhoek, Belgium), electrical resistivity tomography profiles were carried out together with borehole electromagnetic measurements. The latter were used to calculate a vertical variogram, representative of the study site. Then, a geostatistical constraint, in the form of an a priori model covariance matrix based on the variogram, was imposed as regularization to solve the electrical inverse problem. Inversion results enabled to determine the extension of the salt water plume laterally and at depth, but also to estimate the total dissolved solid content within the plume. These results are in agreement with the hydrogeological data of the site. A comparison with borehole data showed that the inversion results with geostatistical constraints are much more representative of the seawater body (in terms of total dissolved solids, extension and height) than results using standard smoothness-constrained inversion. The field results obtained for the Westhoek site emphasize the need to go beyond standard smoothness-constrained images and to use available borehole data as prior information to constrain the inversion. [less ▲]

Detailed reference viewed: 116 (32 ULg)
Full Text
Peer Reviewed
See detailImaging assessment of periaortic inflammation in Erdheim-Chester disease
COUVREUR, Thierry ULg; LIPCSEI, Györgyi; NCHIMI LONGANG, Alain ULg

in Aorta (2013), 1(2), 146-148

Detailed reference viewed: 27 (7 ULg)
Full Text
See detailImaging downward granitic magma transport in the Rogaland anorthosite province, SW Norway
Bolle, Olivier ULg; Trindade, Ricardo I.F.; Diot, Hervé et al

Conference (2002)

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailImaging downward granitic magma transport in the Rogaland Igneous Complex, SW norway
Bolle, Olivier ULg; Trindade, Ricardo I.F.; Bouchez, Jean-Luc et al

in Terra Nova (2002), 14(2), 87-92

Combining geological mapping and petrological, structural and geophysical (gravity and seismic) data already available for the late Proterozoic Rogaland Igneous Complex of Norway allows the 3D shape of ... [more ▼]

Combining geological mapping and petrological, structural and geophysical (gravity and seismic) data already available for the late Proterozoic Rogaland Igneous Complex of Norway allows the 3D shape of the Bjerkreim-Sokndal layered intrusion to be modelled as a thick cumulate series capped by massive granitic rocks. Using the latter data, along with the spectacular convergent linear flow pattern that covers both the cumulates and the felsic rocks of this chamber, evidence is presented to show that the granitic material was down-dragged through the sinking of its high-density mafic floor into lower density anorthosites and granulitic gneisses. This example illustrates that downward gravity-driven flows of rocks were active, in addition to upward flows, in the building of the early crust up to late-Proterozoic times, helping to explain the geochemical and structural complexities of the old crust. [less ▲]

Detailed reference viewed: 30 (1 ULg)
Full Text
Peer Reviewed
See detailIMAGING FINDINGS IN HORSES WITH PHARYNGEAL SQUAMOUS CELL CARCINOMA
Etienne, Anne-Laure ULg; Evrard, Laurence ULg; Bolen, Géraldine ULg et al

Poster (2012)

Introduction Squamous cell carcinoma (SCC) has been occasionally reported in the equine pharyngeal region1-3. The aim of this poster is to describe imaging findings in 4 cases of pharyngeal SCC. Material ... [more ▼]

Introduction Squamous cell carcinoma (SCC) has been occasionally reported in the equine pharyngeal region1-3. The aim of this poster is to describe imaging findings in 4 cases of pharyngeal SCC. Material and methods Four old horses, mean age 19.5, 2 females and 2 geldings, were referred for dyspnea (3/4) and/or dysphagia (3/4). Because of dyspnea radiographs were realized prior to endoscopy. Ultrasound (US) was performed in all cases by ventral and lateral approach using a linear 7,5MHz transducer. A post-mortem computed tomography (CT) of the head was performed in one case (16 slices CT, Somatom 16, Siemens). Results Radiographic opacity of the pharyngeal region was increased in all cases. A soft tissue mass was also visible in the caudal maxillary sinus in 1 horse. The epiglottis was either not recognized or difficult to see with an abnormal shape. Pharyngoepiglottic distance and nasopharyngeal diameter were reduced in all cases. The soft palate was either thick or impossible to be outlined, with an irregular surface. In 1 case it was dorsally displaced. The dorsal pharyngeal wall looked unevenly thickened or impossible to be outlined ventrally due to border effacement. No bony damage was identified on radiographs. A hypoechoic heterogeneous mass was visualized at US in 2 cases and an enlargement of the mandibular lymph nodes was observed in 3 cases. Lymphnodes had also heterogeneous echogenicity and increased doppler signal in 1 case. Oral and pharyngeal endoscopic examination confirmed a pharyngeal mass in 2 cases but was unsuccessful or incomplete because of passage impairment in 2. CT revealed maxillary bone lysis in the horse with a mass in the maxillary sinus. Histopathological examination of local biopsies or necropsy revealed pharyngeal SCC invading epiglottis, pharyngeal wall and soft palate in the 4 horses and the maxillary sinus in one. Discussion/Conclusion Because endoscopy can be impaired by the size of the mass, radiology is helpful in estimating the extent and invasiveness of the process and US to confirm lymphadenopathy. However because of its relatively low sensitivity and the local increased opacity, radiographic examination may underestimate bone lysis. [less ▲]

Detailed reference viewed: 48 (7 ULg)
Full Text
Peer Reviewed
See detailImaging gliomas with positron emission tomography and single-photon emission computed tomography
Bénard, François; Romsa, Jonathan; Hustinx, Roland ULg

in Seminars in Nuclear Medicine (2003), 33(2), 148-162

Over the last two decades the large volume of research involving various brain tracers has shed invaluable light on the pathophysiology of cerebral neoplasms. Yet the question remains as to how best to ... [more ▼]

Over the last two decades the large volume of research involving various brain tracers has shed invaluable light on the pathophysiology of cerebral neoplasms. Yet the question remains as to how best to incorporate this newly acquired insight into the clinical context. Thallium is the most studied radiotracer with the longest track record. Many, but not all studies, show a relationship between Tl-201 uptake and tumor grade. Due to the overlap between tumor uptake and histologic grades, Tl-201 cannot be used as the sole noninvasive diagnostic or prognostic tool in brain tumor patients. However, it may help differentiating a high-grade tumor recurrence from radiation necrosis. MIBI is theoretically a better imaging agent than Tl-201 but it has not convincingly been shown to differentiate tumors according to grade. MDR-1 gene expression as demonstrated by MIBI does not correlate with chemoresistance in high grade gliomas. Currently, MIBI's clinical role in brain tumor imaging has yet to be defined. IMT, a radio-labeled amino acid analog, may be useful for identifying postoperative tumor recurrence and, in this application, appears to be a cheaper, more widely available tool than positron emission tomography (PET). However, its ability to accurately identify tumor grade is limited. 18 F-2-Fluoro-2-deoxy-D-glucose (FDG) PET predicts tumor grade, and the metabolic activity of brain tumors has a prognostic significance. Whether FDG uptake has an independent prognostic value above that of histology remains debated. FDG-PET is effective in differentiating recurrent tumor from radiation necrosis for high-grade tumors, but has limited value in defining the extent of tumor involvement and recurrence of low-grade lesions. Amino-acid tracers, such as MET, perform better for this purpose and thus play a complementary role to FDG. Given the poor prognosis of patients with gliomas, particularly with high-grade lesions, the overall clinical utility of single photon emission computed tomography (SPECT) and PET in characterizing recurrent lesions remains dependent on the availability of effective treatments. These tools are thus mostly suited to the evaluation of treatment response in experimental protocols designed to improve the patients' outcome. (C) 2003 Elsevier Inc. All rights reserved. [less ▲]

Detailed reference viewed: 25 (9 ULg)
See detailImaging Guided Proteomics Unveils Heterogeneity in Colorectal Carcinoma Liver Metastases – Implications for Targeted Therapies
Blomme, Arnaud ULg; Turtoi, Andrei ULg; Castronovo, Vincenzo ULg

Conference (2012, September)

Patients suffering from liver metastases are diagnosed late and have a poor outcome. Targeted therapies are promising treatment options, however the malignant lesions are heterogeneous in nature offering ... [more ▼]

Patients suffering from liver metastases are diagnosed late and have a poor outcome. Targeted therapies are promising treatment options, however the malignant lesions are heterogeneous in nature offering niches for cancer cells to survive and regrow. A rational strategy is needed to select targetable antigens that would overcome this intra-tumoral heterogeneity. MALDI-MS imaging is an emerging tool to study the distribution of biomolecules in tissue samples and is a good base for defining the regions of interest (ROI) that deserve further in-depth analysis. We employed MALDI-MS imaging of colorectal liver metastasis to identify ROI and guide the proteomic analysis for a more in-depth picture of modulated proteins. The focus was laid on cell membrane and extracellular proteins as these have enhanced potential to be used for targeted therapy and clinical imaging applications. Four defined ROI were further analyzed employing 2D-Nano-UPLC-MSe methodology. Over 1500 unique proteins were statistically divided into different patterns of expression, generating a quantitative picture of the proteome heterogeneity in liver metastases. The results offered insight into novel targets but also antigens against which the antibodies are already involved in cancer clinical trials. Following immunohistochemistry based validation experiments, certain proteins demonstrated the potential to homogeneously cover the metastatic lesion and become better targets. Two such antigens, LTBP2 and TGFBI were selected for in vivo functional/ tumor targeting studies in colorectal carcinoma animal model. Importantly, we were able to demonstrate the “targetable” nature of these antigens for homing antibodies injected i.v. Functionally, TGFBI showed an additional potential to target the tumor via it’s ability to affect migration and growth of cancer cells, hence taking the influence on the process of tumorigenesis. In conclusion, liver metastases display a significant heterogeneity in terms of targetable biomarkers and these findings should flow in the future development of targeted therapies aiming to cure the patient. [less ▲]

Detailed reference viewed: 13 (4 ULg)
Full Text
See detailImaging Guided Proteomics Unveils Heterogeniety in Colorectal Carcinoma Liver Metastases – Implications for Targeted Therapies.
blomme, Arnaud; Turtoi, Andrei ULg; Delvaux, David ULg et al

in Proceedings Giga Day 2012 (2012, May 04)

Detailed reference viewed: 42 (20 ULg)
Full Text
Peer Reviewed
See detailImaging in vivo herpes simplex virus thymidine kinase gene transfer and expression in tumors using positron emission tomography.
HUSTINX, Roland ULg; SHIUE, CY.; ZHUANG, H. et al

in Journal of Nuclear Medicine (The) (2000), 41(SUPPL), 264

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailImaging in Vivo Herpes Simplex Virus Thymidine Kinase Gene Transfer to Tumour-Bearing Rodents Using Positron Emission Tomography And
Hustinx, Roland ULg; Shiue, C. Y.; Alavi, A. et al

in European Journal of Nuclear Medicine (2001), 28(1), 5-12

Radiolabelled ganciclovir analogues have shown promise as imaging agents to detect herpes simplex virus thymidine kinase (HSVtk) expression. This study evaluated the use of positron emission tomography ... [more ▼]

Radiolabelled ganciclovir analogues have shown promise as imaging agents to detect herpes simplex virus thymidine kinase (HSVtk) expression. This study evaluated the use of positron emission tomography (PET) imaging with 9-[(3-[18F]fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]FHPG) to assess gene transfer into tumours. HSVtk-positive and HSVtk-negative cell lines were first treated in vitro with [18F]FHPG. To assess the efficacy of PET in detecting HSVtk expression following in vivo gene transfer, mice were injected intravenously with an adenovirus encoding HSVtk (Ad.HSVtk), a control vector (Ad.Bgl2) or saline. Subcutaneous human glioma xenografts were grown in mice and treated by direct injection of Ad.HSVtk or Ad.Bgl2. Imaging was performed 48 h after transduction. Similar experiments were performed using Fischer rats implanted with syngeneic tumours. The presence of the HSVtk protein was confirmed by immunohistochemistry. Biodistribution studies were also obtained in 14 naive mice. In vitro studies showed high and specific uptake of [18F]FHPG in HSVtk-positive cell lines, with an uptake ratio of up to 27:1. PET imaging and direct counting of major organs demonstrated HSVtk-specific tracer retention. In mice, HSVtk-positive tumours retained 3.4% dose/gram as compared to 0.6% for control tumours (P=0.03). They were clearly seen on the PET images as early as 100 min post injection. Similar results were obtained with syngeneic rat tumours. Biodistribution studies demonstrated the rapid distribution and clearance of the tracer in all major organs. Our results demonstrate that PET imaging of HSVtk gene transfer to tumours is feasible and is highly specific for HSVtk expression. [less ▲]

Detailed reference viewed: 9 (1 ULg)
See detailImaging mass spectrometry and proteomics of 3D cell cultures
Longuespée, Rémi ULg; Piron, Céline; Fléron, Maximilien et al

Poster (2013, October)

Detailed reference viewed: 10 (5 ULg)