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See detailExercise-induced dystonia as a preceding symptom of familial Parkinson's disease
Bruno, Michiko K; Ravina, Bernard; Garraux, Gaëtan ULg et al

in Movement Disorders (2004), 19(2), 228-230

Paroxysmal exercise-induced dystonia can occur with Parkinson's disease (PD), and in rare cases, this can also be the presenting symptom. We report on 2 second cousins (no known consanguinity) who ... [more ▼]

Paroxysmal exercise-induced dystonia can occur with Parkinson's disease (PD), and in rare cases, this can also be the presenting symptom. We report on 2 second cousins (no known consanguinity) who presented with paroxysmal exercise-induced dystonia who later developed clinical features of PD. Although autosomal recessive inheritance was suggested, and the dystonic features further suggest parkin as a possible cause, ssequencing for parkin mutations was negative and this family may represent a genetic variant of PD. Further genotype-phenotype studies in this and similar families may give clues to pre-symptomatic symptoms in PD and may reflect a particular phenotype of interest for genetics studies in the future. [less ▲]

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See detailExercise-induced oxidative stress in overweight adolescent girls: roles of basal insulin resistance and inflammation and oxygen overconsumption.
Youssef, H.; Groussard, C.; Pincemail, Joël ULg et al

in International Journal of Obesity & Related Metabolic Disorders (2009), 33(4), 447-55

HYPOTHESIS: Basal insulin resistance (IR) and inflammation exacerbate post-exercise oxidative stress (OS) in overweight adolescent girls. DESIGN: Cross-sectional study, effect of incremental ergocycle ... [more ▼]

HYPOTHESIS: Basal insulin resistance (IR) and inflammation exacerbate post-exercise oxidative stress (OS) in overweight adolescent girls. DESIGN: Cross-sectional study, effect of incremental ergocycle exercise until exhaustion on OS markers. PARTICIPANTS: Normal-weight (control) (n=17, body mass index (BMI): 20-24.2 kg/m(2)) and overweight adolescent girls (n=29, BMI: 24.1-36.6 kg/m(2)). MEASUREMENTS: Dietary measurement, physical activity assessment (validated questionnaires), fat distribution parameters (by dual-energy X-ray absorptiometry and anthropometry) and maximal oxygen consumption (VO2peak). Blood assays include the following: (1) at fasting state: blood cell count, lipid profile, and IR parameters (leptin/adiponectin ratio (L/A), homeostasis model assessment of IR, insulin/glucose ratio; (2) before exercise: inflammation and OS markers (interleukin-6 (IL-6), C-reactive protein (CRP), myeloperoxidase (MPO), reduced glutathione/oxidized glutathione ratio (GSH/GSSG), 15 F(2)alpha-isoprostanes (F(2)-Isop), lipid hydroperoxides (ROOH), oxidized low-density lipoprotein (ox-LDL)) and antioxidant status (superoxide dismutase (SOD), glutathione peroxidase (GPX), vitamin C, alpha-tocopherol and beta-carotene); and (3) after exercise: inflammation and OS markers. RESULTS: At rest, overweight girls had a deteriorated lipid profile and significantly higher values of IR parameters and inflammation markers, compared with the control girls. These alterations were associated with a moderate rest OS state (lower GSH/GSSG ratio, alpha-tocopherol/total cholesterol (TC) ratio and GPX activity). In absolute values, overweight girls exhibited higher peak power output and oxygen consumption (VO2peak), compared with the control girls. Exercise exacerbated OS only in the overweight group (significant increase in F(2)-Isop, ROOH and MPO). As hypothesized, basal IR and inflammation state were correlated with the post-exercise OS. However, the adjustment of F(2)-Isop, ROOH and MPO variation per exercise VO(2) variation canceled the intergroup differences. CONCLUSION: In overweight adolescent girls, the main factors of OS, after incremental exhaustive exercise, are not the basal IR and inflammation states, but oxygen overconsumption. [less ▲]

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See detailExercise-induced physiological adjustments to stressful conditions in sports horses
Art, Tatiana ULg; Lekeux, Pierre ULg

in Livestock Production Science (2005), 92(2), 101-111

Among athletic/sports animals, the horse has a unique ability to increase its oxygen uptake by a factor of 60 during heavy exercise. This is achieved by physiological adaptations of all the links in the ... [more ▼]

Among athletic/sports animals, the horse has a unique ability to increase its oxygen uptake by a factor of 60 during heavy exercise. This is achieved by physiological adaptations of all the links in the oxygen chain. Ventilation is increased by a factor of 30. Since the horse is a compulsory nasal breather, this hyperpnea necessitates high transmural pressure changes, which may be responsible for the dynamic collapse of the airways. Blood flow is increased by a factor of 10. Since the left ventricle is not very compliant, this increase necessitates a high filling pressure in the pulmonary circulation, which may induce capillary stress failure and exercise-induced pulmonary haemorrhage. Lastly, oxygen transport is improved by splenic contraction which increases haemoglobinemia by 50%. Sports horses frequently suffer from several problems, which are related either to endogenous or exogenous stresses experienced during their career. These stresses, caused by the use of the horse as a competition animal, may lead to several medical problems. At a systemic level, endogenous stresses include hyperkaliemia, lactacidemia, and hyperthermia; oxidative stress may induce problems at a general, and/or a pulmonary level. External factors, e.g. poor quality of inspired air, transport, hot and humid ambient conditions, and microbiological agents, may also induce abnormal body attacks, and lead to health problems. [less ▲]

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See detailExercise-induced pulmonary perfusion redistribution in heaves
Harmegnies, N. F.; Duvivier, D. H.; Vandenput, Sandrina ULg et al

in Equine Veterinary Journal. Supplement (2002), 34(suppl), 478-484

This study aimed to compare exercise-induced pulmonary perfusion redistribution in healthy vs. 'heavey' horses using scintigraphy, a minimally invasive technique. Six healthy (A) and 5 'heavey' horses in ... [more ▼]

This study aimed to compare exercise-induced pulmonary perfusion redistribution in healthy vs. 'heavey' horses using scintigraphy, a minimally invasive technique. Six healthy (A) and 5 'heavey' horses in remission (B(I)) and during clinical signs of disease (B(II)) were investigated. Dimensions of the exercising pulmonary perfusion (QE) images were expressed in percent of the resting perfusion (QR) images. Computed QE to QR ratios (QE/QR) images enabled the definition of the region more perfused at exercise than at rest (R1). In all groups, exercise induced a major enlargement of the Q image but a larger increase of the lung height was found in 'heavey' horses. Compared to A, 'heavey' horses showed a larger R1 region with a significantly higher QE/QR. Location of R1 pointed out the dorsal lung region as a major site of pulmonary perfusion redistribution for all groups. This work demonstrated (1) the feasibility of using scintigraphy for studying exercise-induced pulmonary perfusion redistribution; (2) perfusion redistribution to the dorsal lung with exercise and (3) an intensified redistribution in 'heavey' horses, either clinically affected or not. [less ▲]

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See detailExercise-triggered chest pain as an isolated symptom of myocarditis in children
Tshimanga, Prisca; Daron, Benoît; FARHAT, Nesrine ULg et al

in Clinics and Practice (2016)

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See detailExercises in astronomy.
Kleczek, J.; Minnaert, M. G. J.; Allen, D. A. et al

in Exercises in astronomy.. J. Kleczek (Editor).Revised and extended edition of "Practical work in elementary astronomy" by M. G. J. Minnaert. D. ReidelPublishing Co., Dordrecht, The Netherlands. 24+339 pp. Price Dfl. 140.00, US 64.00, £ 49.50 cloth; Dfl. 59.00, US 19.50, £ 18.00 paper (1987). ISBN 90-277-2409-1 cloth, ISBN 90-277-2423-7 paper. (1987)

This book is an updated and considerably extended version of Minnaert's work published in 1969 (01.003.051).Many new exercises referring to new observational techniques and methods have been incorporated ... [more ▼]

This book is an updated and considerably extended version of Minnaert's work published in 1969 (01.003.051).Many new exercises referring to new observational techniques and methods have been incorporated by the editor in collaboration with the contributing authors D. A. Allen, Z. Ceplechka, S. Ferraz Mello, K. J. Gordon, L. Houziaux, C. Jaschek, Z. Kopal, J. Manfroid, J. PalouÅ¡, J. Podolský, G. R. Quast, J. Surdej, A. B. Underhill, J. M. Vreux, D. G. Wentzel.The exercises are organized in the following sections:A. The planetary system: 1. Space and time, instruments. 2. The motions of celestial bodies. 3. Planets and satellites.B. The stars: 1. The Sun. 2. Stars and nebulae. 3. Stellar systems. [less ▲]

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See detailExérèse microchirurgicale atraumatique intranodulaire d'un schwanome bénin du sciatique poplité externe
LEJEUNE, G; LECLERCQ, Daniel ULg; CARLIER, Alain ULg et al

in Actualités chirurgicales - 81ème Congrès Fr. Chirurgie, Orthopédie, Traumatologie (1980)

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See detailExergetic, environmental and economic analysis of a biomass cogeneration plant connected to a district heating network.
Sartor, Kevin ULg; Dewallef, Pierre ULg

in Renewable Energy in the Service of Mankind Vol II (2015)

When a district heating network is fed by natural gas boilers (or biomass boilers), the selection of the network temperature level has a slight influence on the boiler efficiency which means that ... [more ▼]

When a district heating network is fed by natural gas boilers (or biomass boilers), the selection of the network temperature level has a slight influence on the boiler efficiency which means that producing at low temperature allows only to decrease the heat losses through the network. However when a cogeneration plant based on a Rankine cycle is used, lowering the network temperature not only decreases the heat losses but also increase the electrical efficiency while decreasing the thermal efficiency. This aspect is very often overlooked when the quality of a cogeneration plant is assessed by the cogeneration efficiency namely the sum of the electrical and thermal efficiency which is misleading for decision makers. In this contribution, an existing cogeneration plant connected to a district heating network installed on the University Campus in Liège (Belgium) is used as an application test case. Based on actual operational and economic data, a detailed economic evaluation is carried out which is supported by a calibrated simulation model of the whole installation in order to study the influence of the network temperature level. As a second step, the simulation model is used again to perform a detailed exergetic analysis intended to give physical insights to the economical study. This results in a broader discussion on the several methods to assess the quality of cogeneration plants and the opportunity to develop such a technology together with district heating networks. [less ▲]

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See detailExergetic, environmental and economic analysis of a biomass cogeneration plant connected to a district heating network.
Sartor, Kevin ULg

in Book of abstracts of WREC2014 (2014, August 05)

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See detailExergetical Evaluation of Biobased Synthesis Pathways
Frenzel, P; Fayyaz, S; Hillerbrand, R et al

Conference (2011)

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See detailExergetical Evaluation of Biobased Synthesis Pathways
Frenzel, Philipp; Hillerbrand, Rafaela; Pfennig, Andreas ULg

in Polymers (2014), 6(2), 327-345

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See detailExergetische Bewertung der Routen zur stofflichen Nutzung von Biomasse
Frenzel, Philipp; Fayyaz, Sara; Hillerbrand, Rafaela et al

Conference (2011)

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See detailExergetische Bewertung der Routen zur stofflichen Nutzung von Biomasse
Fayyaz, S; Frenzel, P; Hillerbrand, R et al

Conference (2011, May 05)

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See detailExergetische Bewertung neuer Syntheserouten ausgehend von biobasierten Rohstoffen
Fayyaz, Sara; Frenzel, Philipp; Hillerbrand, Rafaela et al

Conference (2011)

See detailExergetische Bewertung neuer Syntheserouten ausgehend von alternativen Kohlenstoffquellen
Frenzel, P; Hillerbrand, R; Pfennig, Andreas ULg

Conference (2012)

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See detailExergy analysis applied to performance of buildings in Europe
Sartor, Kevin ULg; Dewallef, Pierre ULg

in Proceedings (2016)

Energy performance of buildings generally assesses the energy consumption of buildings such as heating, domestic heat water, ventilation systems... However, this approach is based on the first law of ... [more ▼]

Energy performance of buildings generally assesses the energy consumption of buildings such as heating, domestic heat water, ventilation systems... However, this approach is based on the first law of thermodynamics and considers only the quantity of energy used without considering its “quality” and leads to a lack of information about the energy conversion processes. This is particularly true in the new low-energy buildings where sometimes high temperatures sources are used to meet low-temperature needs. The exergy analysis of a system, based on first and second thermodynamic laws, can be used to overcome this. In this work, it is proposed to compare the energy and the exergy consumption of several kinds of buildings to determine the best systems in terms of energy and exergy needs. The energy demand calculations are performed using the official software available in Belgium and some assumptions are implemented to consider the exergy approach. As exergy calculations require a reference state, some different climatic conditions are also investigated. Finally, some conclusions are discussed to rank the sources of energy and their related exergy losses. [less ▲]

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See detailExergySim – Fließschemasimulationen in einem frühen Entwicklungsstadium mit dem Fokus auf Exergiebilanzen
Frenzel, P; Hillerbrand, R; Pfennig, Andreas ULg

Conference (2012, November 13)

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See detailExertional hypoxemia in stable COPD is common and predicted by circulating proadrenomedullin.
Stolz, Daiana; Boersma, Wim; Blasi, Francesco et al

in Chest (2014)

BACKGROUND: The prevalence of exertional hypoxemia in unselected COPD patients is unknown. Intermittent hypoxia leads to adrenomedullin (ADM) up regulation through the HIF-1 pathway. We aimed to assess ... [more ▼]

BACKGROUND: The prevalence of exertional hypoxemia in unselected COPD patients is unknown. Intermittent hypoxia leads to adrenomedullin (ADM) up regulation through the HIF-1 pathway. We aimed to assess the prevalence and the annual probability to develop exertional hypoxemia in stable COPD. We also hypothesized that increased ADM might be associated with exertional hypoxemia and envisioned that adding ADM to clinical variables might improve its prediction in COPD. METHODS: 1233 6-minute walking tests and circulating proadrenomedullin levels from 574 patients with clinically stable, moderate to very severe COPD enrolled in a multinational cohort study and followed-up for 2 years were concomitantly analyzed. RESULTS: The prevalence of exertional hypoxemia was 29.1%. In a matrix derived from a fitted-multi-state model, the annual probability to develop exertional hypoxemia was 21.6%. Exertional hypoxemia was associated with greater deterioration of specific domains of health-related QoL, higher severe exacerbation and death annual rates. In the logistic linear and conditional Cox-regression multivariable analyses, both FEV1% predicted and proADM proved independent predictors of exertional hypoxemia (p<0.001 for both). Adjustment for comorbidities, including cardiovascular disorders, and exacerbation-rate did not influence results. Relative to using FEV1% pred alone, adding proADM resulted in a significant improvement of the predictive properties (p=0.018). Based on the suggested non-linear nomogram, patients with moderate COPD (FEV1 predicted=50%) but high proADM levels (>2nmol/l) presented increased risk (>30%) for exertional desaturation. CONCLUSIONS: Exertional desaturation is common and associated with poorer clinical outcomes in COPD. Adrenomedullin improves prediction of exertional desaturation as compared to the use of FEV1%pred alone. [less ▲]

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