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See detailGiddens et la modernité radicale
Jacquemain, Marc ULg

in Politique : Revue de Débats (2012), 74(mars-avril),

L'article examine brièvement comment la théorie de la modernité réflexive de Giddens, appliquée au domaine de l'intime et de la construction du soi, conduit à sa construction politique de la "troisième ... [more ▼]

L'article examine brièvement comment la théorie de la modernité réflexive de Giddens, appliquée au domaine de l'intime et de la construction du soi, conduit à sa construction politique de la "troisième voie". Le texte défend que, y compris pour les critiques "de gauche" de Giddens, son analyse de la modernité est utile, parce qu'elle décrit - en creux - les limites de la portée émancipatrice de la réflexivité. [less ▲]

Detailed reference viewed: 123 (13 ULg)
See detailGide et la mise en crise de la biographie chez Sartre : Comment peut-on lire L’Idiot de la famille aujourd’hui ?
Cormann, Grégory ULg

in Alexandre, Françoise (Ed.) Biographie d'écrivains, réécriture et réception. Actes du colloque international, Metz, 08 et 09 octobre 2009 (in press)

Detailed reference viewed: 62 (14 ULg)
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See detailGide-Simenon. Une correspondance improbable
Denis, Benoît ULg

in Guyaux, André (Ed.) Échanges épistolaires franco-belges (2007)

Detailed reference viewed: 19 (2 ULg)
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See detailGifted children and the physician
Vanmeerbeek, Marc ULg

Scientific conference (2006, November 05)

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See detailGiftslangen
Fredericq, Léon ULg

in Vlaamse Gids (De) (1909), V

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See detailGIGA ANIMAL CARE : Mice & Zebrafish Animal Facility and Transgenesis
Remy, Benoît ULg; Ectors, Fabien ULg; Winandy, Marie ULg et al

Poster (2014, January 27)

In fundamental research, animal models allow to place molecular and cellular observations back into their physiological context. In applied research, these models still remain a mandatory step to evaluate ... [more ▼]

In fundamental research, animal models allow to place molecular and cellular observations back into their physiological context. In applied research, these models still remain a mandatory step to evaluate the efficiency and the toxicity of potential treatments, before going to clinical trials. Mouse and Zebrafish (Danio rerio) are two very interesting models because of a short live cycle and a high prolificacy. They require a limited space. Their genome is well known and shows a high homology with the human. Many tools are available to produce transgenic mice or zebrafishes. Many tests are validated using both these species. [less ▲]

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See detailGigantism and Acromegaly Due to Xq26 Microduplications and GPR101 Mutation.
Trivellin, Giampaolo; Daly, Adrian ULg; Faucz, Fabio R. et al

in The New England journal of medicine (2014)

Background Increased secretion of growth hormone leads to gigantism in children and acromegaly in adults; the genetic causes of gigantism and acromegaly are poorly understood. Methods We performed ... [more ▼]

Background Increased secretion of growth hormone leads to gigantism in children and acromegaly in adults; the genetic causes of gigantism and acromegaly are poorly understood. Methods We performed clinical and genetic studies of samples obtained from 43 patients with gigantism and then sequenced an implicated gene in samples from 248 patients with acromegaly. Results We observed microduplication on chromosome Xq26.3 in samples from 13 patients with gigantism; of these samples, 4 were obtained from members of two unrelated kindreds, and 9 were from patients with sporadic cases. All the patients had disease onset during early childhood. Of the patients with gigantism who did not carry an Xq26.3 microduplication, none presented before the age of 5 years. Genomic characterization of the Xq26.3 region suggests that the microduplications are generated during chromosome replication and that they contain four protein-coding genes. Only one of these genes, GPR101, which encodes a G-protein-coupled receptor, was overexpressed in patients' pituitary lesions. We identified a recurrent GPR101 mutation (p.E308D) in 11 of 248 patients with acromegaly, with the mutation found mostly in tumors. When the mutation was transfected into rat GH3 cells, it led to increased release of growth hormone and proliferation of growth hormone-producing cells. Conclusions We describe a pediatric disorder (which we have termed X-linked acrogigantism [X-LAG]) that is caused by an Xq26.3 genomic duplication and is characterized by early-onset gigantism resulting from an excess of growth hormone. Duplication of GPR101 probably causes X-LAG. We also found a recurrent mutation in GPR101 in some adults with acromegaly. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and others.). [less ▲]

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See detailLe gigantisme : Les résultats d'une étude clinique et génétique internationale
Rostomyan, Liliya ULg; Daly, Adrian ULg; Lila, A et al

in Annales d'Endocrinologie (2013, October), 74

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See detailLe Gigantisme : Un mystère élucidé
Beckers, Albert ULg

Scientific conference (2003, April 11)

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See detailLe Gigantisme : Un mystère élucidé
Beckers, Albert ULg

Scientific conference (2002, January 22)

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See detailLe Gigantisme : Un mystère élucidé
Beckers, Albert ULg

in Revue Roumaine d'Endocrinologie (2003), 2(4), 88-9394-97

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See detailLe gigantisme : Un mystère élucidé
Beckers, Albert ULg

in Louvain Medical (2003), 122(6), 241-248

L'acromégalie a été décrite par Pierre Marie en 1886. Peu de temps après, il est devenu clair que le gigantisme et l'acromégalie ont la même étiologie: une hypersécrétion d'hormone de croissance, la ... [more ▼]

L'acromégalie a été décrite par Pierre Marie en 1886. Peu de temps après, il est devenu clair que le gigantisme et l'acromégalie ont la même étiologie: une hypersécrétion d'hormone de croissance, la plupart du temps par un adénome hypophysaire, produit un géant si elle a lieu avant l'âge adulte et un acromégale si elle survient après la puberté. Au cours du XXe siècle, cette affection sera caractérisée et divers traitements efficaces mis au point. A la fin du siècle, les mécanismes génétiques responsables de la maladie seront élucidés. [less ▲]

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See detailGigantisme et Acromégalie : Un mystère élucidé
Beckers, Albert ULg

Scientific conference (2003, September)

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See detailLe gigantisme: un mystère élucidé
Beckers, Albert ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2002), 157(1-2), 111-7117-9

Acromegaly was first described by Pierre Marie in 1886. Some years later, it became clear that acromegaly and gigantism share the same etiology: GH hypersecretion due to a pituitary adenoma, induces ... [more ▼]

Acromegaly was first described by Pierre Marie in 1886. Some years later, it became clear that acromegaly and gigantism share the same etiology: GH hypersecretion due to a pituitary adenoma, induces gigantism if already present during puberty, or an acromegalic if it appears only during the adulthood. During the XXth century, the disease has been well described and is now well controlled with several treatments. Recently, genetic alterations responsible for the disease have been elucidated. [less ▲]

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See detail'Gij wurgt mijn keel'. Over Michel Bartosik
Spinoy, Erik ULg

in De Leeswolf (2013), 17(5), 354-355

This text offers a short presentation of the (undeservedly) little-known Flemish poet Michel Bartosik (1948-2008).

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See detailGilbert Boss : la fin de l'ordre économique
Jacquemain, Marc ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (2001), 81-92-93

L'ouvrage propose une transformation radicale des valeurs pour quitter l'ordre marchand. S'il partage des intuitions avec la vision marxiste, il s'en écarte aussi radicalement par son élitisme parfois ... [more ▼]

L'ouvrage propose une transformation radicale des valeurs pour quitter l'ordre marchand. S'il partage des intuitions avec la vision marxiste, il s'en écarte aussi radicalement par son élitisme parfois presque anti-démocratique. On pourrait parler à propos de Gilbert Boss, de socialisme conservateur aristocratique. Une utopie décapante mais pas forcément séduisante. [less ▲]

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See detailGilles Corrozet. Tradition de l'emblème, taxonomie zoologique et morale de l'espace
Strivay, Lucienne ULg

in Marche Romane (1979), XXIX(1-2), 25-39

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See detailGilles de Rais : Quattrocento come noi?
Curreri, Luciano ULg

in Nobili, Sebastiana; Roda, Vittorio; Ruozzi, Gino (Eds.) Studi in onore di Alfredo Cottignoli (2014)

Detailed reference viewed: 23 (0 ULg)