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See detailEvolving Temporal Fuzzy Association Rules from Quantitative Data with a Multi-Objective Evolutionary Algorithm
Matthews, Stephen G.; Gongora, Mario A.; Hopgood, Adrian ULg

in Lecture Notes in Artificial Intelligence (2011), 6678

A novel method for mining association rules that are both quantitative and temporal using a multi-objective evolutionary algorithm is presented. This method successfully identifies numerous temporal ... [more ▼]

A novel method for mining association rules that are both quantitative and temporal using a multi-objective evolutionary algorithm is presented. This method successfully identifies numerous temporal association rules that occur more frequently in areas of a dataset with specific quantitative values represented with fuzzy sets. The novelty of this research lies in exploring the composition of quantitative and temporal fuzzy association rules and the approach of using a hybridisation of a multi-objective evolutionary algorithm with fuzzy sets. Results show the ability of a multi-objective evolutionary algorithm (NSGA-II) to evolve multiple target itemsets that have been augmented into synthetic datasets. [less ▲]

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See detailEvolving temporal fuzzy itemsets from quantitative data with a multi-objective evolutionary algorithm, 
Matthews, S. G.; Gongora, M. A.; Hopgood, Adrian ULg

in Genetic and Evolutionary Fuzzy Systems (GEFS), 2011 IEEE 5th International Workshop on,  (2011)

We present a novel method for mining itemsets that are both quantitative and temporal, for association rule mining, using multi-objective evolutionary search and optimisation. This method successfully ... [more ▼]

We present a novel method for mining itemsets that are both quantitative and temporal, for association rule mining, using multi-objective evolutionary search and optimisation. This method successfully identifies temporal itemsets that occur more frequently in areas of a dataset with specific quantitative values represented with fuzzy sets. Current approaches preprocess data which can often lead to a loss of information. The novelty of this research lies in exploring the composition of quantitative and temporal fuzzy itemsets and the approach of using a multi-objective evolutionary algorithm. This preliminary work presents the problem, a novel approach and promising results that will lead to future work. Results show the ability of NSGA-II to evolve target itemsets that have been augmented into synthetic datasets. Itemsets with different levels of support have been augmented to demonstrate this approach with varying difficulties.,  [less ▲]

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See detailEvolving trends in Latin American politics of biotechnologies: delving into the “GM soya model” in Argentina
Delvenne, Pierre ULg; Vara, Ana Maria; Vasen, Federico

Conference (2011, November 02)

Our interest is to understand the challenges to modern science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly attention has been ... [more ▼]

Our interest is to understand the challenges to modern science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly attention has been paid to existing institutions that may no longer be adequate to address those challenges. This may be because modern institutions are pressured for a greater reflexive opening up of their structures (Beck and Lau 2005) or because the modern world-system is facing severe turbulences that would ultimately lead to a time of structural dissolution (Wallerstein 2005). This renders it interesting to trace the responses to these challenges, and we suggest doing it in the field of STS. Our ongoing multi-level comparative research takes Latin American countries as an entrance point to finding responses that are different from those occurring in European countries. Our presentation is based on Argentina and it focuses on biotechnology in agriculture. Argentina today is the second largest exporter of GM crops and it has been the first country in Latin America to establish a professional regulatory framework in the early 1990s. GM soya crop is specifically analysed because of its importance — more than 60% of the cultivated areas — and its controversial aspect : it is presented at the same time as an elixir for agro-industrial ills and as a techno-economic network increasing the benefits of the global North while dramatically affecting public health and the environment. We suggest diagnosing developments and perceptions of issues related to health, economy, ecological diversity, fertility of soils, regulation and intellectual property. [less ▲]

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See detailEvolving trends in Latin American regimes of science, technology and innovation: the politics of the “GM soya model” in Argentina
Delvenne, Pierre ULg

Conference (2011, June 16)

Our interest is to understand the challenges to modern (national) science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly ... [more ▼]

Our interest is to understand the challenges to modern (national) science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly attention has been paid to existing institutions that may no longer be adequate to address those challenges. This may be because modern institutions are pressured for a greater reflexive opening up of their structures (Beck and Lau 2005) or because the modern world-system is facing severe turbulences that would ultimately lead to a time of structural dissolution (Wallerstein 2005). This renders interesting to trace the responses to these challenges, and we suggest to do it in the field of science, technology and society, one where we can make a contribution. Unlike many studies mainly focusing on European models and regimes, our ongoing multi-level comparative research takes Latin American countries as an entrance point to finding responses that are different from those occuring in European countries. Latin American countries are interesting to study in this respect because institutions of science and technology have not been set up in the same way as in Europe and the governance patterns have been different. Our presentation is based on one country, Argentina, and focuses on one important sector: biotechnology in agriculture. Argentina is taken as a central case study because in addition of being today the second largest exportator of GM crops (behind the US and before Brasil), it has been the first country in Latin America to establish a professional regulatory framework in the early 1990s, looking at ecological, health and commercial aspects. GM soya crops is specifically analysed because of its importance — GM soya represents 60% of the cultivated areas — and its controversial aspect : the « GM soya model » is presented at the same time as an elixir for agro-industrial ills and as a techno-economic network increasing the benefits of the global North while dramatically affecting public health and the environment in Argentina. We suggest to diagnose developments and perceptions of issues related to health, economy, ecological diversity, fertility of soils, regulation and intellectual property. Our methodology favours qualitative data collection (individual interviews with key actors of science and innovation) and analysis, while using quantitative data when available and relevant. [less ▲]

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See detailÉvoquer le "mythe médian". Les imaginaires carolingien et lotharingien dans les revendications territoriales belges à l'égard de l'Allemagne après 1945
Brüll, Christoph ULg

in Revue Belge de Philologie et d'Histoire (2013), (4), 1285-1301

The reference to historical imaginaries and legitimizations for territorial settlements after a military conflict can be considered « classical ». This contribution aims to show how Carolingian and ... [more ▼]

The reference to historical imaginaries and legitimizations for territorial settlements after a military conflict can be considered « classical ». This contribution aims to show how Carolingian and Lotharingian imaginaries influenced certain actors of expansionist movements in Belgium after 1945, the continued existence of which constituted an echo of 1918. Even if the Belgian territorial demands at the expense of Germany were, after all, hardly grounded in such discourses, this contribution highlights the fact that the discourse aiming to transform Aix-la-Chapelle and Cologne into “Belgian” cities, insisting on the kinship between “Belgians” and “Rhinelanders”, would serve as base for the rapprochement between old enemies in the 1950s. From then on, the historical landscape between Meuse and Rhine was integrated in the discourse on the “Occident” (the West) the political organization of which was considered as of utmost necessary, given the impending Soviet menace. [less ▲]

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See detailEvualation of the microbiota in foods with metagenetics
Delhalle, Laurent ULg

Conference (2015)

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See detailEx Parrot: The Aarhus-Sydney gamma Dor experiment on pulsations and rotation
Antoci, V.; Ouazzani, R.; Murphy, S. et al

Poster (2015, June 01)

γ Doradus stars, exhibiting pure gravity modes pulsations, occupy the region between the solar-like oscillators and the delta Sct stars in the HRD. The Kepler mission delivered data of unprecedented ... [more ▼]

γ Doradus stars, exhibiting pure gravity modes pulsations, occupy the region between the solar-like oscillators and the delta Sct stars in the HRD. The Kepler mission delivered data of unprecedented quality spanning up to 4 years, allowing to resolve closely spaced modes to measure, e.g., period spacings and to infer internal rotation profiles. Here we present an ensemble study of all γ Doradus stars observed with the Kepler mission. We investigate among others the range of excited modes, their amplitudes and the impact of rotation on these quantities. Our aim is to better understand the pulsation excitation as well as the mode selection mechanism in these stars. Our results may help to also explain the lack of solar-like oscillators exhibiting g-modes pulsations on the main sequence, although the instability domains of γ Doradus and solar-like stars overlap. [less ▲]

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See detailEx iusta causa traditum: Essays in Honour of Eric H. Pool
Van den Bergh, Rena; van Niekerk, Gardiol; Thomas, Philip et al

Book published by UNISA (2005)

Detailed reference viewed: 144 (0 ULg)
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See detailEx vivo bioluminescent detection of alcelaphine herpesvirus 1 infection during malignant catarrhal fever induced in rabbits
Dewals, Benjamin G ULg; Myster, Françoise ULg; Massart, François et al

Poster (2009, December 11)

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. Experimentally, WD-MCF can be reproduced in rabbits. The lesions observed are very similar to those described in natural host species. Recently, we demonstrated that WD-MCF induced by AlHV-1 in rabbits is associated with the proliferation of CD8+ cells supporting a latent type of infection. In the present study, we investigated whether the virus could be detected ex vivo in the tissues of rabbits developing WD-MCF. Taking advantage of the recent cloning of the AlHV-1 genome as a bacterial artificial chromosome (BAC), we produced a recombinant plasmid encoding a firefly luciferase (LUC) expression cassette inserted in a non-coding region of the AlHV-1 genome. In vitro, the reconstituted AlHV-1 LUC strain replicated comparably to the parental strain in permissive cells and was able to induce a bioluminescent signal. In vivo, rabbits infected with the AlHV-1 LUC strain developed WD-MCF similarly to the parental wild-type strain with hyperthermia, increased CD8/CD4 ratio and viral genomic charge over time in PBMC and in lymph nodes at time of death. To identify the presence of AlHV-1 infection ex vivo, various organs of infected rabbits developing WD-MCF were analysed by bioluminescent imaging. Luciferase activity could be detected macroscopically at the time of death in most of analyzed organs including lung, popliteal and mesenteric lymph nodes, spleen, liver, kidney and appendix. Infectious virus could be isolated following co-cultures of lymph node and permissive cells, and the isolated virus retained the ability to induce a bioluminescent signal. In conclusion, we produced an AlHV-1 LUC recombinant and we were able to detect the AlHV-1 infection ex vivo in many organs at the time of death. [less ▲]

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See detailEx vivo bioluminescent detection of Alcelaphine herpesvirus 1 infection during malignant catarrhal fever.
Dewals, Benjamin G ULg; Myster, Françoise ULg; Palmeira, Leonor ULg et al

in Journal of Virology (2011), 85(14), 6941-54

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. Experimentally, WD-MCF can be reproduced in rabbits. WD-MCF is described as a combination of lymphoproliferation and degenerative lesions in virtually all organs and caused by unknown mechanisms. Recently, we demonstrated that WD-MCF is associated with the proliferation of CD8(+) cells supporting a latent type of infection in lymphoid tissues. Here, we investigated the macroscopic distribution of AlHV-1 infection using ex vivo bioluminescence imaging in rabbit to determine whether it correlates with the distribution of lesions in lymphoid and non-lymphoid organs. To reach that goal, a recombinant AlHV-1 strain was produced by insertion of a luciferase expression cassette (luc) in an intergenic region. In vitro, the reconstituted AlHV-1 luc(+) strain replicated comparably to the parental strain and luciferase activity was detected by bioluminescence imaging. In vivo, rabbits infected with the AlHV-1 luc(+) strain developed WD-MCF comparably to the parental wild-type strain with hyperthermia and increase of both CD8(+) T cells frequencies and viral genomic charge over time in peripheral blood mononuclear cells and in lymph nodes at time of euthanasia. Bioluminescent imaging revealed that AlHV-1 infection could be detected ex vivo in lymphoid organs but also in lung, liver and kidney during WD-MCF, demonstrating that AlHV-1 infection is prevalent in tissue lesions. Finally, we show that the infiltrating mononuclear leukocytes in non-lymphoid organs are mainly CD8(+) T cells and that latency is predominant during WD-MCF. [less ▲]

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See detailEx Vivo Evaluation of p-[18F]D-MPPF for the Study of 5-HT1A Receptors.
Defraiteur, C.; Lemaire, Christian ULg; Luxen, André ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (2005), 48

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See detailEx vivo expansion of hematopoietic progenitor cells is associated with downregulation of alpha4 integrin- and CXCR4-mediated engraftment in NOD/SCID beta2-microglobulin-null mice
Foguenne, Jacques ULg; Di Stefano; Giet, Olivier ULg et al

in Haematologica (2009), 94

Several studies indicate that ex vivo cytokine-supported expansion induces defective hematopoietic stem cell engraftment. We investigated the role of alpha4 integrin, alpha5 integrin and CXCR4 in ... [more ▼]

Several studies indicate that ex vivo cytokine-supported expansion induces defective hematopoietic stem cell engraftment. We investigated the role of alpha4 integrin, alpha5 integrin and CXCR4 in engraftment of unmanipulated and cytokine-treated human cord blood CD34+ cells. [less ▲]

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See detailEx vivo ruminal cellulosome for by-product biomass conversion
Hissette, Mathias ULg; Destain, Jacqueline ULg; Thewis, André ULg et al

Conference (2011, April 27)

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See detail(Ex)communication
Dumortier, Jean-Louis ULg

in Lettre de la DLFM (2003), 32

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See detail(Ex-)smoking asthma patients in general and specialized Belgian practice.
Decramer, M.; Louis, Renaud ULg; Joos, G. et al

in Respiratory medicine (2011), 105(8), 1203-1210

INTRODUCTION: Smokers are often excluded from asthma studies. In the present study, data are presented on the prevalence, characteristics and management approach of this patient population in the Belgian ... [more ▼]

INTRODUCTION: Smokers are often excluded from asthma studies. In the present study, data are presented on the prevalence, characteristics and management approach of this patient population in the Belgian practice both at the level of general practitioners (GPs) and specialists. MATERIALS AND METHODS: One hundred and nineteen smoking, non-smoking and ex-smoking patients (25-65 yrs) with asthma, COPD or both, were recruited by 33 GPs and 33 specialists. Data were obtained retrospectively from medical records. However, only a small number of files were complete. RESULTS: The majority of COPD patients were (ex-)smokers: 94% in the specialist group, 78% in the GP group. Cardiovascular comorbidity appeared in both groups in the same frequency order: COPD>(ex-)smoking patients with asthma (AS)>non-smoking patients with asthma (ANS), with a significant difference between AS and ANS in the specialist population. Chronic cough during more than 3 months in two consecutive years was reported in 97% of COPD patients, in 71% of the AS patients and in only 25% of the ANS patients. The type of cough differed between AS and ANS in the GP group, with a higher prevalence of productive cough in the former. Treatment patterns observed were as expected according to diagnosis except for a disproportionate use of Tiotropium in AS in the GP group. CONCLUSION: AS were somewhere in between COPD patients and ANS for a large number of the characteristics studied, suggesting that they are an intermediate phenotype between COPD and asthma. [less ▲]

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See detailEx-situ’ conservation of Antarctic cyanobacteria : a culture collection to explore diversity and bioactivity
Wilmotte, Annick ULg; Renard, Marine ULg; Kleinteich, J et al

Poster (2014, August)

Cyanobacteria appear as the dominant phototrophs in Antarctic terrestrial and freshwater ecosystems. Since 2011, the Belgian Science Policy Office has funded the BCCM/ULC public collection of (sub)polar ... [more ▼]

Cyanobacteria appear as the dominant phototrophs in Antarctic terrestrial and freshwater ecosystems. Since 2011, the Belgian Science Policy Office has funded the BCCM/ULC public collection of (sub)polar cyanobacteria. It is currently holding 102 Antarctic cyanobacterial strains and the catalogue is available on http://bccm.belspo.be/db/ulc_search_form.php. A Quality Management System was implemented and an ISO9001 certificate was obtained for the public deposition and distribution of strains. The strains are kept as living cultures, and their cryopreservation is in progress. The Antarctic cyanobacterial strains were isolated from samples of the three main biogeographic provinces. The purpose of this public collection is to gather a representative portion of the cyanobacterial diversity with different ecological origins (limnetic microbial mats, soil crusts, cryoconites, endoliths, etc.) and make it available for researchers to study the diversity, evolution, adaptations to the environmental conditions, and genomic make-up. Three cyanobacterial orders are represented: Chroococcales, Oscillatoriales and Nostocales. This is particularly important in view of the emerging use of metagenomic approaches on environmental samples, where the comparisons with the genome sequences from well-defined strains is very useful. They could also serve as references for compounds such as fatty acids and pigments. In addition, cyanobacteria produce a range of secondary metabolites (e.g. alkaloides, cyclic and linear peptides, polyketides) with different bioactive potential (e.g. antibiotic, antiviral, anticancer, cytotoxic, genotoxic). Bioassays have shown antifungal activities of the cell extracts of strains Plectolyngbya hodgsonii ULC009 and Phormidium priestleyi ULC026. Due to the geographic isolation and the strong environmental stressors of the habitat, the exploration of these metabolites in Antarctic cyanobacterial strains seems especially promising for biotechnology or biomedical applications. In summary, the BCCM/ULC public collection could serve as a general reference for Antarctic cyanobacteria with multiple applications, as well as a resource for novel bioactive compounds. [less ▲]

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See detail‘Ex-situ’ preservation and characterization of Antarctic cyanobacteria in the BCCM/ULC collection
Kleinteich, Julia ULg; Renard, Marine ULg; Simons, Véronique et al

Poster (2015, June 09)

The BCCM/ULC public collection of (sub)polar cyanobacteria is funded since 2011 by the Belgian Science Policy Office. An ISO9001 certificate was obtained for the public deposition and distribution of ... [more ▼]

The BCCM/ULC public collection of (sub)polar cyanobacteria is funded since 2011 by the Belgian Science Policy Office. An ISO9001 certificate was obtained for the public deposition and distribution of strains, as part of the multi-site certification for the BCCM consortium. BCCM/ULC is currently holding 160 public cyanobacterial strains and the catalogue is available on http://bccm.belspo.be/catalogues/ulc-catalogue-search. Continuous maintenance of living cultures, some of which are also cryopreserved, ensure the preservation and the possibility to rapidly deliver strains to clients for fundamental and applied research. The main holding of the collection concerns (sub)polar strains isolated from different biotopes and representative of a large taxonomic diversity. The molecular characterization is underway, on the basis of 16S rRNA and ITS sequences, but also Multiple Locus Sequence Analysis and genome sequencing. In addition, cyanobacteria are known to produce a range of secondary metabolites (e.g. alkaloides, cyclic and linear peptides, polyketides) with various bioactive potential. The presence of genes involved in the production of microcystin is currently studied by PCR, and analytical methods are used to confirm the toxin production. Due to the geographic isolation and the strong environmental stressors of the habitat, the exploration of these metabolites in Antarctic cyanobacterial strains seems especially promising for biotechnology or biomedical applications. [less ▲]

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See detailEx-vivo cytokine production by whole blood cells from cancer patients
De Groote, Donat; Vrindts-Gevaert, Yvonne; Lopez Y Cadenas, Miguel ULg et al

in Cancer Detection & Prevention (1996), 20

Detailed reference viewed: 24 (6 ULg)