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See detailL'hypnosedation, un nouveau mode d'anesthesie pour la chirurgie endocrinienne cervicale. Etude prospective randomisee.
Defechereux, Thierry ULg; Degauque, C.; Fumal, I. et al

in Annales de Chirurgie (2000), 125(6), 539-46

Retrospective studies have confirmed the feasibility and safety of thyroid and parathyroid procedures performed under hypnoanesthesia (hypnosis, local anesthesia and minimal conscious sedation) as sole ... [more ▼]

Retrospective studies have confirmed the feasibility and safety of thyroid and parathyroid procedures performed under hypnoanesthesia (hypnosis, local anesthesia and minimal conscious sedation) as sole method of anesthesia. This very effective technique seems to provide physiological, psychological and economic benefits for the patient. STUDY AIM: To assess, by means of a prospective randomized study, the advantages of hypnosedation as an alternative to general anesthesia in terms of clinical and laboratory parameters. PATIENTS AND METHODS: Twenty patients operated under hypnoanesthesia were compared to 20 patients operated under conventional anesthesia. The two groups were compared in terms of inflammatory, neuroendocrine, hemodynamic and immunologic parameters and postoperative course (pain, fatigue, muscle strength and stress). RESULTS: No clinical or demographic differences were observed between the two groups. Operative times, bleeding, weight of specimens, and surgical comfort were similar. Significant differences in terms of inflammatory response and hemodynamic parameters were observed in favor of hypnoanesthesia. Neuroendocrine and immunological parameters were similar. Patients of the hypnoanesthesia group had significantly less postoperative pain. Postoperative fatigue syndrome and convalescence were significantly improved in these patients. CONCLUSION: This study confirms that, in our hands, hypnosedation presents real advantages over general anesthesia, in patients undergoing thyroid surgery. [less ▲]

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See detailHypnosedation: a valuable alternative to traditional anaesthetic techniques.
Faymonville, Marie-Elisabeth ULg; Meurisse, Michel ULg; Fissette, Jean ULg

in Acta Chirurgica Belgica (1999), 99(4), 141-6

Hypnosis has become routine practice in our plastic and endocrine surgery services. Revivication of pleasant life experiences has served as the hypnotic substratum in a series of over 1650 patients since ... [more ▼]

Hypnosis has become routine practice in our plastic and endocrine surgery services. Revivication of pleasant life experiences has served as the hypnotic substratum in a series of over 1650 patients since 1992. In retrospective studies, followed by randomised prospective studies, we have confirmed the usefulness of hypnosedation (hypnosis in combination with conscious IV sedation) and local anaesthesia as a valuable alternative to traditional anaesthetic techniques. The credibility of hypnotic techniques and their acceptance by the scientific community will depend on independently-confirmed and reproducible criteria of assessing the hypnotic state. Based on the clinical success of this technique, we were interested in confirming this phenomenon in healthy volunteers. The revivication of pleasant life experiences thus served as the cornerstone of a basic research program developed to objectify the neurophysiological attributes of the hypnotic state. We compared hypnosis to normal alertness with similar thought content. In our experience, the activation profile obtained during the hypnotic state was completely different from simple re-memoration of the same subject matter during normal alertness. This represents an objective and independent criteria by which to assess the hypnotic state. [less ▲]

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See detailHypnosédation: une nouvelle technique anesthésique
Kirsch, Murielle ULg; Joris, Jean ULg; Faymonville, Marie ULg

in Hypnose et Thérapies brèves (2006), 2

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See detailL'hypnosédation: une technique nouvelle d'anesthésie en chirurgie endocrine cervicale
Defechereux, Thierry ULg; Meurisse, Michel ULg; Joris, Jean ULg et al

in Michaux, Didier (Ed.) Douleur et Hypnose. Deuxième partie: Le traitement des douleurs organiques et psychogènes (2004)

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See detailHypnosis and cingulate-mediated mechanisms of analgesia
FAYMONVILLE, Marie-Elisabeth ULg; Vogt, Brent; Maquet, Pierre ULg et al

in Vogt, Brent (Ed.) Cingulate Neurobiology and Disease (2009)

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See detailHypnosis as adjunct therapy in conscious sedation for plastic surgery
Faymonville, Marie ULg; Fissette, Jean ULg; Mambourg, P.-H. et al

in Regional Anesthesia (1995), 20(2), 145-151

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See detailHypnosis for pain management
MALAISE, Nicole ULg; SALAMUN, Irène ULg; PALMARICCIOTTI, Valérie ULg et al

in Fernandez de las Penas, César; Chaitow, Léon; Schoenen, Jean (Eds.) Multidisciplinary management of migraine : pharmacological, manual and other therapies (2012)

The purposes of this chapter are : - to provide a brief definition of hypnosis, hypnotic process and self-hypnosis. - to describe briefly the neurophysiological correlates of hypnosis and hypnotic ... [more ▼]

The purposes of this chapter are : - to provide a brief definition of hypnosis, hypnotic process and self-hypnosis. - to describe briefly the neurophysiological correlates of hypnosis and hypnotic analgesia. - to propose a short review of recent literature concerning the effectiveness of clinical hypnosis in chronic pain, emphasizing more specifically research on the effectiveness of hypnosis with migraine. - to address some questions about its daily clinical use. [less ▲]

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See detailHypnosis with conscious sedation instead of general anaesthesia? Applications in cervical endocrine surgery.
Meurisse, Michel ULg; Defechereux, Thierry ULg; Hamoir, Etienne ULg et al

in Acta Chirurgica Belgica (1999), 99(4), 151-8

Between April 1994 and June 1997, 197 thyroidectomies and 21 cervical explorations for hyperparathyroidism were performed under hypnosedation (HYP) and compared to the operative data and postoperative ... [more ▼]

Between April 1994 and June 1997, 197 thyroidectomies and 21 cervical explorations for hyperparathyroidism were performed under hypnosedation (HYP) and compared to the operative data and postoperative courses of a closely-matched population (n = 121) of patients operated on under general anaesthesia (GA). Conversion from hypnosis to GA was needed in two cases (1%). All surgeons reported better operating conditions for cervicotomy using HYP. All patients having HYP reported a very pleasant experience and had significantly less postoperative pain while analgesic use was significantly reduced in this group. Hospital stay was also significantly shorter, providing a substantial reduction of the medical care costs. The postoperative convalescence was significantly improved after HYP and full return to social or professional activity was significantly shortened. We conclude that HYP is a very efficient technique providing physiological, psychological and economic benefits to the patient. [less ▲]

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See detailHypnosis-related analgesia: a thulium-YAG fMRI study
Vanhaudenhuyse, Audrey ULg

Conference (2007)

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See detailHypnotic modulation of resting state fMRI default mode and extrinsic network connectivity
Demertzi, Athina ULg; Soddu, Andrea ULg; FAYMONVILLE, Marie-Elisabeth ULg et al

in Progress in Brain Research (2011), 193

Resting state fMRI (functional magnetic resonance imaging) acquisitions are characterized by low-frequency spontaneous activity in a default mode network (encompassing medial brain areas and linked to ... [more ▼]

Resting state fMRI (functional magnetic resonance imaging) acquisitions are characterized by low-frequency spontaneous activity in a default mode network (encompassing medial brain areas and linked to self-related processes) and an anticorrelated “extrinsic” system (encompassing lateral frontoparietal areas and modulated via external sensory stimulation). In order to better determine the functional contribution of these networks to conscious awareness, we here sought to transiently modulate their relationship by means of hypnosis. We used independent component analysis (ICA) on resting state fMRI acquisitions during normal wakefulness, under hypnotic state, and during a control condition of autobiographical mental imagery. As compared to mental imagery, hypnosis-induced modulation of resting state fMRI networks resulted in a reduced “extrinsic” lateral frontoparietal cortical connectivity, possibly reflecting a decreased sensory awareness. The default mode network showed an increased connectivity in bilateral angular and middle frontal gyri, whereas its posterior midline and parahippocampal structures decreased their connectivity during hypnosis, supposedly related to an altered “self” awareness and posthypnotic amnesia. In our view, fMRI resting state studies of physiological (e.g., sleep or hypnosis), pharmacological (e.g., sedation or anesthesia), and pathological modulation (e.g., coma or related states) of “intrinsic” default mode and anticorrelated “extrinsic” sensory networks, and their interaction with other cerebral networks, will further improve our understanding of the neural correlates of subjective awareness. [less ▲]

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See detailHypnotic techniques
FAYMONVILLE, Marie-Elisabeth ULg; BEJENKE, Christel; HANSEN, Ernil

in Cyna, Allan; Andrew, Marion; Tan, Suyin (Eds.) et al Handbook of Communication in Anaesthesia and Critical Care (2010)

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See detailHypo- et hypertension intracrânienne bénigne
DELVAUX, Valérie ULg; DIOH, Alioune ULg; Schoenen, Jean ULg

in Revue Médicale de Liège (1999), 54(8), 671-676

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See detailHypo- et hypertension intracrâniennes bénignes
DELVAUX, Valérie ULg; DIOH, Alioune ULg; Schoenen, Jean ULg

in Ahead in neurology (1999), 3(1), 10-15

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See detailHypocalcémie induite chez le sujet pagétique par la calcitonine salmine nasale. Effets des anticorps anti-calcitonine salmine
Reginster, Jean-Yves ULg; Almer, S.; Gaspar, S et al

in Revue du Rhumatisme et des Maladies Osteo-Articulaires (1989), 56(7), 563-7

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See detailHypochlorous acid activates NF-kappaB transcription factor in T lymphocytes
Schoonbroodt, Sonia; Legrand-Poels, Sylvie ULg; Best-Belpomme, Martin et al

in Biochemical Journal (1997)

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See detailHypochlorous Acid, a Major Oxidant Produced by Activated Neutrophils, Has Low Effect on Two Pyridobenzazepine Derivatives, Jl 3 and Jl 13
Liégeois, Jean-François ULg; Zahid, N.; Bruhwyler, J. et al

in Archiv der Pharmazie (2000), 333(2-3), 63-7

JL 13 (5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b]- [1,5]benzoxazepine fumarate) and JL 3 (10-(4-methylpiperazin-1- yl)pyrido[4,3-b][1,4]benzothiazepine), two pyridobenzazepine derivatives ... [more ▼]

JL 13 (5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b]- [1,5]benzoxazepine fumarate) and JL 3 (10-(4-methylpiperazin-1- yl)pyrido[4,3-b][1,4]benzothiazepine), two pyridobenzazepine derivatives structurally related to clozapine, were selected for further development. Due to their structural similarity to clozapine, they are haunted by the spectre of clozapine-induced agranulocytosis. In a previous study, JL 13 was shown to be less sensitive to oxidation than clozapine. In the present paper, using an in vitro procedure, we report the effect of hypochlorous acid (HOCl), a major in vivo oxidant, on both drugs. It appears that the oxidations of JL 3 and JL 13, unlike clozapine, are very slow and little secondary product is formed. Moreover, in contrast to clozapine, the products that were formed are not reactive and thus do not react with glutathione or N-acetylcysteine. Thus, if, as postulated for clozapine, drug-induced agranulocytosis is due to a reactive metabolite formed by neutrophils or their precursors, JL 3 and JL 13 would not be expected to cause the same adverse reaction. [less ▲]

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See detailL'hypochondroplasie: dystrophie héréditaire
Reginster, Jean-Yves ULg; FOIDART-DESSALLE, Marguerite ULg; Leroy, C et al

in Revue Médicale de Liège (1986), 61

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See detailHypochromic mature erythrocytes: a specific marker of iron deficiency
Bovy, Christophe ULg; Beguin, Yves ULg; Gothot, André ULg et al

in Acta Clinica Belgica (2003), 58-3(4), 325

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See detailHypocortisolism induces chronic respiratory failure
PIRLET, Charles ULg; BECK, Emmanuel ULg; SCHEEN, André ULg et al

in Respiratory Medicine (2011), 4(3), 107-108

Hypocortisolism is an uncommon condition. Its association with myopathy and respiratoryfailure has only rarely been described. We report the case of a 52 year-old woman presenting with progressive ... [more ▼]

Hypocortisolism is an uncommon condition. Its association with myopathy and respiratoryfailure has only rarely been described. We report the case of a 52 year-old woman presenting with progressive dyspnoea. Work-up revealed a severe restrictive syndrome with hypoxaemia. Further investigations showed hypocortisolism of pituitary origin. Response to hydrocortisone allowed us to conclude to an unusual case of hypocortisolic myopathy affecting the respiratory muscles. [less ▲]

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See detailHypodermose bovine dans le Nord-Est algérien : prévalence et intensité d'infestation
Benakhla, A.; Lonneux, J. F.; Mekroud, A. et al

in Veterinary Research (1999), 30

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