(596) Scheila

in Central Bureau Electronic Telegrams (CBETs) (2011), 2632

E. Jehin, J. Manfroid, D. Hutsemekers, M. Gillon, and P. Magain, Fonds National de la Recherche Scientifique, Liege University, report on broad- and narrow-band imaging of the (596) Scheila outburst (CBET ... [more ▼]

E. Jehin, J. Manfroid, D. Hutsemekers, M. Gillon, and P. Magain, Fonds National de la Recherche Scientifique, Liege University, report on broad- and narrow-band imaging of the (596) Scheila outburst (CBET 2583) with the TRAPPIST 0.60-m telescope at La Silla, and on optical spectroscopy with the European Southern Observatory's Very Large Telescope (VLT) at Paranal. R-band imaging from 2010 Dec. 12.3 to 21.3 UT revealed two arc-like coma features expanding at a regular pace. The first such feature was 1' long on 2010 Dec. 12, oriented to the northeast and bending to p.a. 280 deg (the anti-solar direction). The second feature was shorter, 30" on Dec. 12, oriented to the south and bending to p.a. 230 deg. Both features were getting larger and fainter with time (4' and 2' long, respectively, on Dec. 21.3). A narrow 45"-long tail, opposite the sun (p.a. 280 deg), was also observed in good seeing. R-band images taken on 2011 Jan. 4.3 and 5.3 after the full moon allowed Jehin et al. to again observe these features, seen as 7' and 4' long, respectively -- and much fainter. This discards any sustained activity of the minor planet. Narrow-band images obtained on 2010 Dec. 12.3 with cometary filters do not show any contribution from gases. A 20-min optical spectrum was obtained with FORS2 at the VLT on Dec. 13.3; it does not show any extended cometary gaseous emissions, but only a spatially extended continuum due to dust-scattered sunlight. Short B, V, R, and I exposures performed nearly every two nights from 2010 Dec. 12.3 to 2011 Jan. 5.3 give a magnitude for the nuclear condensation of V = 14.2 +/- 0.1 over the whole period, in agreement with the "APmag" value reported in the Jet Propulsion Laboratory ephemeris. No flux variation of the nuclear condensation was observed. Those preliminary results are in favor of a collisional scenario to explain the outburst of (596) Scheila, rather than a cometary driven activity. This case might be similar to the outburst of comet P/2010 A2, which may have resulted from an impact of a minor planet (Snodgrass 2010, Nature 467, 814). [less ▲]

6 - Functional analysis of the lithics

in Vermeersch, Pierre M. (Ed.) The Ahrensburgian at Zonhoven-Molenheide (Belgium) (2013)

6,7-Disubstituted 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides: new potent ATP-sensitive potassium channel openers

Poster (2002, September)

A 6-hour nocturnal interruption of a continuous subcutaneous insulin infusion: 1. Metabolic and hormonal consequences and scheme for a prompt return to adequate control.

in Diabetologia (1983), 24(5), 314-8

Interruption of a continuous subcutaneous insulin infusion, most often due to technical problems occurring during the night, is a not uncommon event whose metabolic consequences have received relatively ... [more ▼]

Interruption of a continuous subcutaneous insulin infusion, most often due to technical problems occurring during the night, is a not uncommon event whose metabolic consequences have received relatively little attention until now. We have therefore investigated the changes in blood glucose, plasma non-esterified fatty acids, 3-hydroxybutyrate, glucagon and free insulin in eight C-peptide negative Type 1 diabetic patients whose pumps were deliberately stopped between 23.00 h and 05.00 h. A control test with the pump functioning normally was carried out in each patient and the studies were randomized. Considering the values at 23.00 h as reference, interruption of the insulin infusion resulted in (1) a rapid decrease in plasma free insulin significant after 1 h and reaching a nadir of 6 +/- 2 mU/l after 6 h; (2) a rise in blood glucose which was significant at hour 3 and reached 17.4 +/- 1.9 mmol/l at hour 6; (3) a moderate increase in plasma nonesterified fatty acids which remained in the range of 700-800 mumol/l; (4) an early and linear rise in plasma 3-hydroxybutyrate, significant after 1 h and averaging 1290 +/- 140 mumol/l after 6 h; (5) a late increase (hour 5) in plasma glucagon. The second aim of our study was to provide for the patient a precise scheme of insulin supplements administered via the pump and based on blood glucose monitoring (Dextrostix - Glucometer) and semi-quantitative evaluation of ketonuria (Acetest). Resetting the pump at its basal rate at 05.00 h and giving insulin supplements (2-8 U) at 06.45 h (with the usual breakfast dose) and again at 10.00 h have proved efficacious in restoring satisfactory metabolic control by noon the day after starting the experiment. These results form practical recommendations to patients undergoing this type of accident. [less ▲]

6-Substituted 2-oxo-2H-1-benzopyran-3-carboxylic acid as a core structure for selective inhibitors of human leucocyte elastase

in Journal of Medicinal Chemistry (1999), 42

6-Substituted benzopyran derivatives as potent KATP channel openers: synthesis and biological in vitro evaluation

Poster (2008, May)

6. Lutte intégrée contre les maladies

in Bodson, Bernard; Destain, Jean-Pierre (Eds.) Livre Blanc - Céréales (2013, February 27)

60 h of anhepatic state without neurologic deficit

in Transplant International (2006), 19(9), 769-769

The "666" collaboration on OGLE transits. I. Accurate radius of the planets OGLE-TR-10b and OGLE-TR-56b with VLT deconvolution photometry

in Astronomy and Astrophysics (2007), 465

Transiting planets are essential to study the structure and evolution of extra-solar planets. For that purpose, it is important to measure precisely the radius of these planets. Here we report new high ... [more ▼]

Transiting planets are essential to study the structure and evolution of extra-solar planets. For that purpose, it is important to measure precisely the radius of these planets. Here we report new high-accuracy photometry of the transits of OGLE-TR-10 and OGLE-TR-56 with VLT/FORS1. One transit of each object was covered in Bessel V and R filters, and treated with the deconvolution-based photometry algorithm DECPHOT, to ensure accurate millimagnitude light curves. Together with earlier spectroscopic measurements, the data imply a radius of 1.22{[SUP]+0.12[/SUP][SUB]-0.07[/SUB]} R[SUB]J[/SUB] for OGLE-TR-10b and 1.30 ± 0.05 R[SUB]J[/SUB] for OGLE-TR-56b. A re-analysis of the original OGLE photometry resolves an earlier discrepancy about the radius of OGLE-TR-10. The transit of OGLE-TR-56 is almost grazing, so that small systematics in the photometry can cause large changes in the derived radius. Our study confirms both planets as inflated hot Jupiters, with large radii comparable to that of HD 209458b and at least two other recently discovered transiting gas giants. Based on data collected with the FORS1 imager at the VLT-Kueyen telescope (Paranal Observatory, ESO, Chile) in the programme 177.C-0666E. [less ▲]

The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolution.

in Molecular Biology and Evolution (1998), 15(8), 1017-25

The 67-kDa laminin receptor (67LR) is a nonintegrin cell surface receptor that mediates high-affinity interactions between cells and laminin. Overexpression of this protein in tumor cells has been related ... [more ▼]

The 67-kDa laminin receptor (67LR) is a nonintegrin cell surface receptor that mediates high-affinity interactions between cells and laminin. Overexpression of this protein in tumor cells has been related to tumor invasion and metastasis. Thus far, only a full-length gene encoding a 37-kDa precursor protein (37LRP) has been isolated. The finding that the cDNA for the 37LRP is virtually identical to a cDNA encoding the ribosomal protein p40 has suggested that 37LRP is actually a component of the translational machinery, with no laminin-binding activity. On the other hand, a peptide of 20 amino acids deduced from the sequence of 37LR/p40 was shown to exhibit high laminin-binding activity. The evolutionary relationship between 23 sequences of 37LRP/p40 proteins was analyzed. This phylogenetic analysis indicated that all of the protein sequences derive from orthologous genes and that the 37LRP is indeed a ribosomal protein that acquired the novel function of laminin receptor during evolution. The evolutionary analysis of the sequence identified as the laminin-binding site in the human protein suggested that the acquisition of the laminin-binding capability is linked to the palindromic sequence LMWWML, which appeared during evolution concomitantly with laminin. [less ▲]