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See detailHumoral and cellular immune response to a Microsporum canis recombinant keratinolytic metalloprotease (r-MEP3) in experimentally infected guinea pigs
Brouta, Frédéric; Descamps, Frédéric; Vermout, Sandy et al

in Medical Mycology (2003), 41(6), 495-501

In order to better understand the host-fungus relationship in Microsporum canis dermatophytosis and to identify major fungal antigens, the immune response to a crude exoantigen preparation and to a ... [more ▼]

In order to better understand the host-fungus relationship in Microsporum canis dermatophytosis and to identify major fungal antigens, the immune response to a crude exoantigen preparation and to a purified recombinant keratinolytic metalloprotease (r-MEP3) was evaluated in guinea pigs experimentally infected with M. canis. Humoral and cellular immune responses were assessed from day 0 to day 57 post-infection (PI), the former by enzyme-linked immunosorbent assay (ELISA) and the latter via a lymphocyte proliferation assay. Infected guinea pigs developed humoral and cellular responses to both M. canis exoantigen and r-MEP3, while no specific immune response to these antigens was observed in control animals. This is the first report on the development of both humoral and cell-mediated immune responses to a purified keratinase in M. canis dermatophytosis. [less ▲]

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See detailHumoral antibody response to bovine leukemia virus infection in cattle and sheep.
Bex, Françoise; Bruck, Claudine; Mammerickx, Marc et al

in Cancer Research (1979), 39(3), 1118-1123

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See detailHumoral Immune Response in Calves to Single-Dose, Trickle and Challenge Infections with Fasciola Hepatica
Bossaert, K.; Farnir, Frédéric ULg; Leclipteux, Thierry ULg et al

in Veterinary Parasitology (2000), 87(2-3), 103-23

In cattle experimentally infected with Fasciola hepatica, parasite specific IgG1 and IgG2 responses were studied. Additionally parasite specific IgE production was assessed by the Passive Cutaneous ... [more ▼]

In cattle experimentally infected with Fasciola hepatica, parasite specific IgG1 and IgG2 responses were studied. Additionally parasite specific IgE production was assessed by the Passive Cutaneous Anaphylaxis reaction. The primary infection was administered either as a single-dose or as a trickle infection over a 4-week period. Animals were challenged 4 months later. Titres of IgG1 and IgG2 against excretory-secretory parasite products (FhESAg), and against a whole-worm extract (FhSomAg) were measured by enzyme-linked immunosorbent assay (ELISA) in relation to weight gain, serum hepatic enzyme levels, and fluke infection rate. At necropsy, the mean number of flukes recovered was similar in both infected groups. The two ELISAs specific for bovine IgG1 showed analogous sensitivity and specificity (92% and 94%). Cross-reactivity was observed towards Echinococcus granulosus, Cysticercus tenuicollis, and C. ovis but not towards C. bovis, Cooperia spp., and Ostertagia spp. FhESAg gave rise to apparently more stable specific IgG1 titres as compared to FhSomAg. Mean IgG1 titres were significantly higher in the single-dose-infected group than in the trickle-infected group during the early migratory phase of the infection (week 2 to week 4 (FhSomAg) or week 6 (FhESAg)). IgG2 values were consistently lower than IgG1 levels. The kinetic response of both isotypes yielded a similar pattern. Specific IgE antibodies were detected in cattle of both infected groups from week 2 post-primary infection (PPI) onwards. The mean serum glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gammaGT) activities were significantly higher in the single-dose-infected group for 3 weeks around peak levels (12-14 weeks PPI and 14-16 weeks PPI for GLDH and gammaGT respectively). Western blotting revealed a major antigenic fraction in FhESAg (26-30 kDa) recognized specifically by sera from F. hepatica infected calves as early as 6-8 weeks PPI. Experimental challenge caused no statistically significant modification of any parameter (IgG1 and IgG2 titres, enzymatic activities, immunoblotting) used to monitor the course of the infection. No correlation was found between fluke size and number, and antibody titres, suggesting that IgG1 production has little protective effect against F. hepatica infection. [less ▲]

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See detailL'humour à la croisée des rapports interculturels
Defays, Jean-Marc ULg

in Cahiers francophones d'Europe Centre-Orientale (1995), I(5/6), 57-66

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See detailL'humour de Madame Bovary
Saint-Amand, Denis ULg

Conference given outside the academic context (2013)

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See detail« L’humour toujours l’humour (suite et fin) »
Demoulin, Laurent ULg; Aron, Paul

in Carnet et les Instants (2011), 165

Suite et fin de l'exploration de l'humour dans la littérature belge.

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See detail« L’humour toujours l’humour (suite) »
Demoulin, Laurent ULg

in Carnet et les Instants (2010), 164

Etude succincte de l'absurde chez quelques écrivains belges des XXe et XXIe siècles.

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See detailL'humour: le texte au banc d'essai
Defays, Jean-Marc ULg

Conference (1990, September)

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See detailThe hunt for early eukaryotes in Archean and Proterozoic oceans
Javaux, Emmanuelle ULg; Knoll, A. H.; Marshall, C. P. et al

Poster (2003)

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See detailHunting for a key to the enigma of heaves in the black box of the white cells
Art, Tatiana ULg; Bureau, Fabrice ULg; Robinson, N Edward

in Veterinary Journal (2008), 177(3), 307-308

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See detailHuntingtin is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis
Godin, Juliette ULg; Colombo, kelly; Molina-Calavita, Maria et al

in Neuron (2010), 67(3)

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See detailHuntingtin Mediates Anxiety/Depression-Related Behaviors and Hippocampal Neurogenesis
M'Barek, Karim Ben; Pla, Patrick; Orvoen, Sophie et al

in The Journal of Neuroscience (2013), 33(20), 8608-8620

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See detailHuntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis.
M'Barek, K. Ben; Orvoen, S.; Pla, P. et al

Poster (2012)

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See detailHuntingtine, a key protein in development
Godin, Juliette ULg; Humbert, Sandrine

in Biofutur (2012), (328), 54-57

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See detailHuntingtine, mitose et destinée cellulaire
Godin, Juliette ULg; Humbert, S.

in Medecine Sciences : M/S (2011), 27(2), 126-128

[No abstract available]

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See detailHuntington’s Disease: From the Physiological Function of Huntingtin to the Disease
Borgs, Laurence ULg; Godin, Juliette ULg; Malgrange, Brigitte ULg et al

in Huntington's Disease - Core Concepts and Current Advances (2012)

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