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See detailGuidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).
Camm, A John; Kirchhof, Paulus; Lip, Gregory Y H et al

in European Heart Journal (2010), 31(19), 2369-429

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See detailGuidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).
Camm, A John; Kirchhof, Paulus; Lip, Gregory Y H et al

in Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology (2010), 12(10), 1360-420

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See detailGuidelines for the management of chronic hepatitis C in patients infected after substance use
Robaeys, G.; Buntinx, F.; Bottieau, E. et al

in Acta Gastro-Enterologica Belgica (2005), 68(1), 38-45

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See detailGuidelines for the management of osteoarthritis
Bruyère, Olivier ULg

Conference (2011, March 24)

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See detailGuidelines for the transfusion of red cells
Baele, Philippe; Muylle, L.; Noens, L. et al

in Acta Clinica Belgica (2008), 63(5), 301-312

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See detailGuidelines for the use of epoetin: have quality-of-life benefits been proven?
Bottomley, Andrew; Thomas, Ronald; Van Steen, Kristel ULg et al

in Journal of Clinical Oncology (2003), 21(11), 22232224-5

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See detailGuidelines for trials of drug treatments in tension-type headache
Schoenen, Jean ULg

in Olesen, J.; Tfelt-Hansen, P. (Eds.) Headache treatment: Trial methodology and new drugs (1997)

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See detailGuidelines for Trials of Drug Treatments in Tension-Type Headache. First Edition: International Headache Society Committee on Clinical Trials
Schoenen, Jean ULg

in Cephalalgia : An International Journal of Headache (1995), 15(3), 165-79

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See detailGuidelines of the Belgian Hematological Society for newly diagnosed and relapsed follicular lymphoma 2012
Debussche, S.; Van Hoof, A.; Sonet, Anne et al

in Belgian Journal of Hematology (2012), 3(2), 41-50

Follicular lymphoma is an indolent lymphoma that has occurred more frequently over the last decades. In this article we present an overview of the diagnosis and initial work-up, prognostic scoring system ... [more ▼]

Follicular lymphoma is an indolent lymphoma that has occurred more frequently over the last decades. In this article we present an overview of the diagnosis and initial work-up, prognostic scoring system and choice of therapy. For limited stage disease radiotherapy is the treatment of choice, and may have a curative potential. For advanced stages treatment should be initiated upon certain criteria, and is essentially based on immunochemotherapy, rituximab plus chemotherapy. The choice of chemotherapy depends on age, frailty, and specific toxicities of chemotherapy. Maintenance therapy with rituximab after induction has become standard practice. Since virtually all patients relapse eventually, an overview of the treatment in the relapsed setting is given. The treatment is then again based on immunochemotherapy but there is also a place for radio-immunotherapy, or immunotherapy alone. For young patients, high dose chemotherapy with autologous stem cell rescue should be considered. A brief overview on novel agents, and agents that are in the pipeline, is given. We conclude with some recommendations for follow-up. [less ▲]

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See detailGuidelines on myocardial revascularization.
Kolh, Philippe ULg; Wijns, William; Danchin, Nicolas et al

in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2010), 38 Suppl

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See detailThe guidelines on the application of article 81(3) EC: A critical review
Petit, Nicolas ULg

in Working Paper Institut d'Etudes Juridiques Européennes (2009)

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See detailGuidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS).
Vahanian, Alec; Alfieri, Ottavio; Andreotti, Felicita et al

in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2012), 42(4), 1-44

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See detailGuidelines to Adapt the General Principles of the Non-statistical Meta-analysis Method to Specific Fields of Biomedical Research: the Example of Molecular Oncology.
Pasleau, Françoise ULg; Delvenne, Catherine ULg; Cielniaszek, Nadine

in Libraries without limits : changing needs – changing roles Proceedings of the 6th European Conference of medical and Health Libraries. (1999)

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational ... [more ▼]

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational orientation are responsible for this gap. Effective information management at the institutional level, could provide clinicians the means to adopt new perspectives. At present, the link between basic research and clinical application relies upon the motivation of individuals to develop new skills in literature retrieval and analysis and yet their occupational responsabilities inhibit this endeavour. Academic librarians, educated and trained in information and biomedical sciences, have a role in providing physicians with current and readily applicable knowledge from the critical analysis of the literature. The Faculty of Medicine Library is developing a research programme to design an updated and comprehensive picture of the diagnostic and prognostic biological markers in the field of human prostate cancer. The final product is envisioned as a database accessible on the web that will integrate bibliographic analyses and results from prospective and retrospective studies conducted at the University of Liège. As this product is designed to have a direct impact on clinical decision making and patient care, it should guarantee thoroughness, relevancy and objectivity and not become yet another narrative review of the literature. Over the last decade, there has been a movement towards using statistical meta-analyses to synthesize literature. This method has proven to be useful when similar strategies are used to produce similar quantitative outcomes that can be merged for statistical analysis.1 Even though studies in cancer research assess the same model, they are often too fragmented or heterogeneous in their design, methods and instrumentation. Approaches have been developed to conduct non-statistical meta-analysis of such publications.2 Quantitative and qualitative meta-analyses are based on common principles which are largely discussed in the literature. They are related to model development, literature coding, rating references for quality and annotating and synthesizing high quality references. In practice, these basic principles require translation into actual instructions adapted to every domain of biomedical research. Variable definition is a very critical step that governs the quality of subsequent analyses. Specific examples provided illustrate the guidelines acquired from our experience. Il s'écoule souvent un intervalle de temps fort long avant que les nouveaux concepts issus de la recherche biomédicale soient intégrés dans la pratique médicale courante. Les raisons de cette situation sont autant d'ordre économique et technique que culturel. Actuellement, les liens entre la recherche fondamentale et la médecine clinique ne peuvent exister que sur base d'initiatives individuelles et les médecins concernés doivent investir une partie de leur temps dans l'apprentissage des techniques de recherche et d'analyse de la littérature. Une gestion professionnelle de l'information au niveau d'une institution telle qu'un hôpital universitaire devrait par contre inciter davantage de cliniciens à utiliser les ressources de la littérature issue de la recherche biomédicale. C'est pourquoi la Bibliothèque de la Faculté de Médecine de l'Université de Liège propose, à titre expérimental, de créer un prototype de site web consacré à l'étude des marqueurs pronostiques et diagnostiques du cancer de la prostate. Des scientifiques, spécialisés en sciences biomédicales et formés aux techniques de gestion documentaire, fourniront à l'intention des médecins spécialistes et/ou généralistes, voire des patients eux-mêmes, une analyse critique de la littérature en relation directe avec les activités cliniques de l'institution. Notre objectif étant de fournir aux médecins des informations susceptibles d'être utilisées comme bases de décision clinique, notre responsabilité se trouve engagée vis à vis des patients. Nous devrons donc définir une stratégie qui garantisse à la fois l'exhaustivité et la pertinence de l'information traitée et l'objectivité des analyses présentées. Sur base des principes de la méta-analyse,1,2 nous avons conçu un protocole en cinq étapes comprenant: la définition à priori des objectifs, la recherche non biaisée d'information, la définition de critères de sélection des études, l'extraction et la synthèse des données. La difficulté consistera à traduire ces principes en une série de consignes pratiques et techniques et d'en dégager des lignes de conduite générales qui permettront d'étendre cette approche à n'importe quel domaine de la médecine. 1. D'Agostino RB, Weintraub M. Meta-analysis: a method for synthesizing research. Clin Pharmacol Ther 1995;58:605-616 2. Bland CJ, Meurer LN, Maldonado G. A systematic approach to conducting a non-statistical meta-analysis of research literature. Acad Med 1995;70:642-653 [less ▲]

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See detailGuidelines to Adapt the General Principles of the Non-statistical Meta-analysis Method to Specific Fields of Biomedical Research: the Example of Molecular Oncology.
Pasleau, Françoise ULg; Delvenne, Catherine ULg; Cielnaszek, Nadine

Conference (1998, June 26)

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational ... [more ▼]

In most circumstances, considerable time lags before results from biomedical research are integrated in general medical practice are inevitable. Several economic, technical factors and educational orientation are responsible for this gap. Effective information management at the institutional level, could provide clinicians the means to adopt new perspectives. At present, the link between basic research and clinical application relies upon the motivation of individuals to develop new skills in literature retrieval and analysis and yet their occupational responsabilities inhibit this endeavour. Academic librarians, educated and trained in information and biomedical sciences, have a role in providing physicians with current and readily applicable knowledge from the critical analysis of the literature. The Faculty of Medicine Library is developing a research programme to design an updated and comprehensive picture of the diagnostic and prognostic biological markers in the field of human prostate cancer. The final product is envisioned as a database accessible on the web that will integrate bibliographic analyses and results from prospective and retrospective studies conducted at the University of Liège. As this product is designed to have a direct impact on clinical decision making and patient care, it should guarantee thoroughness, relevancy and objectivity and not become yet another narrative review of the literature. Over the last decade, there has been a movement towards using statistical meta-analyses to synthesize literature. This method has proven to be useful when similar strategies are used to produce similar quantitative outcomes that can be merged for statistical analysis.1 Even though studies in cancer research assess the same model, they are often too fragmented or heterogeneous in their design, methods and instrumentation. Approaches have been developed to conduct non-statistical meta-analysis of such publications.2 Quantitative and qualitative meta-analyses are based on common principles which are largely discussed in the literature. They are related to model development, literature coding, rating references for quality and annotating and synthesizing high quality references. In practice, these basic principles require translation into actual instructions adapted to every domain of biomedical research. Variable definition is a very critical step that governs the quality of subsequent analyses. Specific examples provided illustrate the guidelines acquired from our experience. 1. D'Agostino RB, Weintraub M. Meta-analysis: a method for synthesizing research. Clin Pharmacol Ther 1995;58:605-616 2. Bland CJ, Meurer LN, Maldonado G. A systematic approach to conducting a non-statistical meta-analysis of research literature. Acad Med 1995;70:642-653 [less ▲]

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See detailGuillain-Barré syndrome following hepatitis E
Loly, Jean-Philippe ULg; Rikir, Estelle ULg; Seivert, Maxime ULg et al

in World Journal of Gastroenterology (2009), 15(13), 1645-1647

Guillain-Barré syndrome (GBS) is often triggered by a preceding bacterial or viral infection. Occasionally, it has been observed in association with acute hepatitis A, B and C, and three cases have been ... [more ▼]

Guillain-Barré syndrome (GBS) is often triggered by a preceding bacterial or viral infection. Occasionally, it has been observed in association with acute hepatitis A, B and C, and three cases have been previously described in India in which GBS was associated with acute hepatitis E. A molecular mimicry mechanism is supposed to be involved in the pathogenesis of GBS triggered by infectious agents, although the nature of the shared epitopes has not been characterized in most instances, including that in the case of hepatotropic viruses. We report a case of GBS following acute hepatitis E in a European individual. The presence of antiganglioside GM2 antibodies in this patient suggested molecular mimicry involving ganglioside GM2 in the pathogenesis of GBS associated with hepatitis E. [less ▲]

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See detailGuillaume le Blanc, la dislocation de la voix des précaires
Herla, Anne ULg

in Jeanmart, Gaëlle (Ed.) Mépris et reconnaissance sociale. Donner une voix à ceux dont la parole ne compte pas. (2011)

Detailed reference viewed: 7 (0 ULg)