How licensing can address new challenges? The question of brokering
Conference given outside the academic context (2010)Detailed reference viewed: 18 (1 ULg)
How Mannheimia haemolytica defeats host defence through a kiss of death mechanism
Zecchinon, Laurent ; Fett, Thomas ; Desmecht, Daniel
in Veterinary Research (2005), 36(Mar-Apr), 133-156
Mannheimia haemolytica induced pneumonias are only observed in goats, sheep and cattle. The bacterium produces several virulence factors,whose principal ones are lipopolysaccharide and leukotoxin. The ... [more ▼]
Mannheimia haemolytica induced pneumonias are only observed in goats, sheep and cattle. The bacterium produces several virulence factors,whose principal ones are lipopolysaccharide and leukotoxin. The latter is cytotoxic only for ruminant leukocytes, a phenomenon that is correlated with its ability to bind and interact with the ruminant beta2-integrin Lymphocyte Function-associated Antigen 1. This paper globally reviews all the information available on host-pathogen interactions underlying respiratory mannheimiosis (formerly pasteurellosis), from the stable and the Petri dish to the biochemical cascade of events triggered by the leukotoxin inside ruminant leukocytes. One conclusion can be made: the most widespread cattle respiratory disease with the most important impact on beef production worldwide, is probably due to a tiny ruminant-specific focal variation in the CD18- and/or CD11a-expressing genes. [less ▲]Detailed reference viewed: 20 (1 ULg)
How many nursery pigs can eat at one wet/dry feeder space
Laitat, Martine ;
Article for general public (2002)Detailed reference viewed: 12 (0 ULg)
How many scribes worked on the Egyptian Recension of the Thouand and One Nights?...
Conference (2013, October 11)Detailed reference viewed: 10 (1 ULg)
How many species in the Black rat complex (Rattus rattus sensu lato) in Southeast Asia?
Pagès, Marie ; ; et al
Conference (2011, July)
Black rats are among the major invasive vertebrates with severe ecological, economic and health impacts. Remarkably, the evolutionary history of black rats has received little attention and there is no ... [more ▼]
Black rats are among the major invasive vertebrates with severe ecological, economic and health impacts. Remarkably, the evolutionary history of black rats has received little attention and there is no firm agreement as how many species should be recognized within the Rattus rattus complex. Members of the species complex are native from India and Southeast Asia. Current taxonomy suggests that four taxa live in sympatry in several places of Thailand and Cambodia where the present study was conducted: three accepted species (R. tanezumi, R. losea, R. argentiventer) and an additional lineage of unclear taxonomic status sometimes referred as Rattus R3. We used an extensive sampling, morphological data and diverse genetic markers of different evolutionary rates and parental inheritance (two mtDNA genes, one nuclear gene and eight microsatellite loci) to assess the genetic structure among the four taxa. Genetic analyses revealed discordant patterns between the mt and the nuclear data. The mt phylogeny identified three reciprocally monophyletic clades corresponding to the four putative taxa while the nuclear phylogeny failed to separate tanezumi and R3. Within geographic localities, microsatellites revealed free gene flow between tanezumi and R3 but no gene flow between those two taxa and losea or argentiventer. Altogether theses analyses do not support the taxon R3 as a valid species and advocate for synonymy with tanezumi. As a consequence, R. tanezumi becomes paraphyletic with respect to losea. Simulation analyses are now ongoing to determine whether a recent speciation event between tanezumi and losea, or an incomplete lineage sorting within tanezumi could explain this uncommon pattern. [less ▲]Detailed reference viewed: 22 (1 ULg)
How many women can benefit from a full intrapartum antibiotic prphylaxis for prevention of perinatal group B streptococcal disease?
MELIN, Pierrette ; ; et al
in American Society of Microbiology (Ed.) Program and Abstracts of the 44th Intersciences Conference on Antimicrobial Agents and Chemotherapy (2004, November)
Background: In Belgium as in many Western countries, GBS are still the leading cause of severe perinatal infections. Current guidelines for prevention recommend intrapartum antimicrobial prohylaxis (IAP ... [more ▼]
Background: In Belgium as in many Western countries, GBS are still the leading cause of severe perinatal infections. Current guidelines for prevention recommend intrapartum antimicrobial prohylaxis (IAP) administered promptly before delivery to pregnant women colonized with GBS. The risk of vertical GBS transmission to the newborn decreases as the duration of prophylaxis increases. The considered threshold for prophylaxis adequacy is the first dose administered at least 4 hours before delivery. Objective: To evaluate the proportion of pregnant women who could benefit from an adequate IAP for the prevention of GBS perinatal infections. Methods: Between June and October 2003, we recorded in two hospitals the elapse time between admission for labor and delivery. We assumed 5 hours represent a useful threshold to allow admission, revision of chart and administration of adequate IAP. The status of vaginal colonization with GBS was determined by CDC’s recommended culture method with Granada agar added. Results: Among 532 women, 27.3 % delivered within 5 hours after admission for labor. The colonization rate for GBS was 25.6 %. The distribution of elapse time between admission and delivery for GBS colonized pregnant women was not significantly different from non colonized women (p <= 1). Conclusions: 1) With the current prevention strategy, 27.3 % of these pregnant women would not have benefit from adequate prophylaxis 2) These results highlight the importance of an efficient organization to warranty prompt administration of IAP as soon as possible when mandatory. 3) If a rapid intrapartum screening test is used, no delay can be afforded “from ward to bench to bed”. [less ▲]Detailed reference viewed: 14 (1 ULg)
How measuring glomerular filtration rate? Comparison of reference methods
in Sahay, Manisha (Ed.) Basic Nephrology and Acute Kidney Injury (2012)Detailed reference viewed: 13 (0 ULg)
How Measuring Glomerular Filtration Rate? Comparison of reference methods
in Sahay, Manisha (Ed.) Basic Nephrology and Acute Kidney injury (2012)Detailed reference viewed: 13 (6 ULg)
How modeling can reconcile apparently discrepant experimental results: the case of pacemaking in dopaminergic neurons.
Drion, Guillaume ; Massotte, Laurent ; Sepulchre, Rodolphe et al
in PLoS Computational Biology (2011), 7(5), 1002050Detailed reference viewed: 117 (37 ULg)
How Much Discretion do, and should, Competition Authorities enjoy in the Course of their Enforcement Activities? A Multi-Jurisdictional Assessment
in Concurrences : Revue des Droits de la Concurrence (2010), (1), 44-62
The purpose of this study is to assess whether competition agencies (“CAs”) do, and in turn should, enjoy an unfettered discretionary power in the context of the investigation of competition law ... [more ▼]
The purpose of this study is to assess whether competition agencies (“CAs”) do, and in turn should, enjoy an unfettered discretionary power in the context of the investigation of competition law infringements or whether their margin of discretion should be subject to certain limits. To this end, it focuses on four successive areas where CAs may be entitled to make choices, i.e. detection of infringements, selection of enforcement targets, initiation of infringement proceedings and outcome of the case. Thanks to reports received from 21 national experts in response to a questionnaire covering 18 jurisdictions, the present study formulates a number of public policy proposals. [less ▲]Detailed reference viewed: 99 (10 ULg)
How much is enough?
in Onco : Revue Multidisciplinaire d'Oncologie (2008), 2(6), 221-222
Le traitement conservateur est une constante dans l’approche oncologique. Des efforts ont été développés afin de conserver au maximum l’intégrité de la fonction et/ou de l’image corporelle. Ce souci de ... [more ▼]
Le traitement conservateur est une constante dans l’approche oncologique. Des efforts ont été développés afin de conserver au maximum l’intégrité de la fonction et/ou de l’image corporelle. Ce souci de sauvegarde se traduit par des approches thérapeutiques non mutilantes: un exemple typique est le changement de paradigme thérapeutique au moment de l’introduction de la chirurgie conservatrice de la glande mammaire en lieu et place de la mastectomie. Ce concept de chirurgie non radicale a été possible grâce à l’association avec la radiothérapie externe postopératoire. Des essais randomisés ont permis de valider le concept et de démontrer que le risque de rechute loco-régionale et ultérieurement la survie ne sont pas modifiés comparés à une approche chirurgicale potentiellement délabrante. Ces essais randomisés ne se sont fort heureusement pas limités aux aspects purement oncologiques. De façon prospective on a pu déterminer l’excellence des résultats cosmétiques à moyen et à long terme. Il est vrai que cette approche par essais randomisés était un passage indispensable et a permis de valider ce concept thérapeutique. Il aurait été pour le moins étonnant de prôner d’emblée une approche chirurgicale non mutilante mais oncologiquement complète, si à terme le résultat esthétique aurait été inférieur à celui que l’on aurait pu escompter après mastectomie radicale suivie de reconstruction. [less ▲]Detailed reference viewed: 24 (6 ULg)
How much is residents' distress detection performance during a clinical round related to their characteristics?
; ; et al
in Patient Education & Counseling (2011)Detailed reference viewed: 3 (2 ULg)
How much time does it take for "experience design" to unfold?
Elsen, Catherine ; Leclercq, Pierre
in Benz, Peter (Ed.) Designing Experiences: Positions and Approaches. (2014)
This paper specifically focuses on one aspect of the experience design process, sometimes even stressed as one if its shortcomings: the time it takes to properly gain insights about possible real-life ... [more ▼]
This paper specifically focuses on one aspect of the experience design process, sometimes even stressed as one if its shortcomings: the time it takes to properly gain insights about possible real-life experiences of proximal or distal end-users. In the process of making sense of sometimes conflicting viewpoints found in the literature about timing and its possible impact on design processes and outcomes, this paper compares four distinct settings and addresses the following research questions: • How “time-framing” the design process possibly filters (positively or negatively) the awareness designers have about end-users; • How the experimental protocols, their inherent limitations and artificialities, do shape the designers’ involvement in the process of designing for an end-user’s experience. Results put techniques for «disciplined creativity», such as brainstorming or analogies, front-to-front with more reflective approaches that unfold over more time, and discuss respective but complementary added values of both. [less ▲]Detailed reference viewed: 26 (3 ULg)
How Not to Die in Venice : The Art of Arakawa and Madeline Gins
in dworkin, Craig (Ed.) Architectures of Poetry (2004)Detailed reference viewed: 20 (0 ULg)
How nurses support students' reflective learning in clinical placements?
Conference (2013, September 06)Detailed reference viewed: 8 (0 ULg)
How Old Is Old Enough to Vote. Youth Participation in Society
; Fournier, Bernard
in Perspectives électorales/Electoral Insight (2003), 5(2), 38-43Detailed reference viewed: 129 (2 ULg)
How phosphorus availability is influenced by agricultural practices
Barbieux, Sophie ; Hiel, Marie-Pierre ; Bodson, Bernard et al
Poster (2014, January 07)Detailed reference viewed: 20 (10 ULg)
How powerful is demography? The Serendipity Theorem revisited
Pestieau, Pierre ; ;
in Journal of Population Economics (2012), 25Detailed reference viewed: 9 (1 ULg)
How precisely will the total cross section be measured at the LHC?
Cudell, Jean-René ;
in Physical Review Letters (2009), 102
It is very likely that hadronic scattering will enter a new regime at the LHC, as the black-disk limit is reached. This will lead to a severe change in the t dependence of the real part and of the slope ... [more ▼]
It is very likely that hadronic scattering will enter a new regime at the LHC, as the black-disk limit is reached. This will lead to a severe change in the t dependence of the real part and of the slope of the elastic scattering amplitude, and in turn this may bias the measurement of the total cross section. We examine this issue, and suggest new strategies to test the reliability of the total cross section measurements. [less ▲]Detailed reference viewed: 133 (6 ULg)