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See detailL'étude biologique du travail
Duesberg, Jules ULg

Speech/Talk (1938)

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See detailEtude biomecanique articulaire chez le cheval par tribometrie et analyse dynamique inverse
Noble, Prisca ULg

Doctoral thesis (2010)

In locomotor biomechanics, three groups of constraints are usually encountered : pressure, traction and torsion (Kamina, 2005). In supra-maximal conditions, all of these contraints would be responsible ... [more ▼]

In locomotor biomechanics, three groups of constraints are usually encountered : pressure, traction and torsion (Kamina, 2005). In supra-maximal conditions, all of these contraints would be responsible for some disease of equine locomotor systems (Radin et al., 1972 ; Radin, 1983 ; Smith et al., 2002). In order to understand better the constraints in the equine locomotor dynamics, some investigations have been carried out. Moreover, some measurement methods, based on the mechanics of Newton, have been performed. This work consists of three different experimental approaches: The first approach was an ex vivo micro-systemic model of the diarthrodial cartilage-cartilage contact : from osteochondral specimens in contact, dynamic frictional constraints were measured by tribometry using a pin-on-disc tribometer in Coulomb’s regime. The effects of age and load on the frictional response were studied. The second approach was an ex vivo macro-systemic model of the diarthrodial cartilage-cartilage contact : from whole fetlock joints fixed into an original pendulum tribometer and mobilized, dynamic visco-frictional constraints have been followed in viscous regime. The effect of a lipid solvent on the synovial fluid was studied. The third approach was an in vivo macro-systemic model of the diarthrodial cartilage-cartilage contact : from distal forelimbs, cinematic, cinetic and radiographic data have been collected, then tendon tensions and joint contact forces components were calculated using an inverse dynamic analysis. From a sensitivity analysis, the effect of raised hell (0°, 6°, 12°) were elucidated. In the first approach : (i) an original equine joint friction test model using a cartilage-on-cartilage arrangement (pin-on-disc) has been performed, (ii) cartilage ageing was found, under experimental operating conditions, to be responsible for an increase in friction coefficient, (iii) lubrication remained stable when young cartilage was loaded whereas lubrication of older cartilage was affected by increased load. In the second approach : (i) an original equine joint pendulum tribometer has been designed, (ii) visco-frictionnal data have confirmed the joint pendulum damping can be modelled like a harmonic oscillator fluid damping, (iii) the lipid solvent injection into the fetlock joint increased the visco-frictional parameters of the joint and the damping time decreased, suggesting that the lubrication capacity was compromised. In the third approach : (i) an original equine distal limb model with tendinous variable pulleys was described, (ii) polynomial relationships of second order between the variation of the dorsal angle of the fetlock joint and the moment arm variation of the deep digital and superficial digital flexors tendons have been established, (iii) the joint contact force components of the coffin joint and of the fetlock joint have been calculated during the phase of the trot, (iv) the effect of raised heel on the tendinous tensions and on the joint contact force components was established, suggesting that the use of heel wedges to reduce the loading of the coffin joint may in fact increase the loading of the fetlock joint. The two ex vivo equine articular models (tribometry) are some original and complementary mechanical analysis tools: the pin-on-disc tribometer may highlight the mechanical properties of the triplex cartilage-synovial fluid-cartilage that are related with the structural properties (contact surface), and the pendulum tribometer may clarify the mechanical properties of the articular lubricant in a very realistic intra-articular environment (quasi anaerobic). These two tools could be used to characterize the mechanical properties of some new articular prosthesis and lubricants in the future. Finally, the numerical in vivo model (dynamic inverse analysis), calculating dynamic tendinous tensions and dynamic joint contact force components in the equine distal forelimb, is equally a very interressing and original tool. Indeed, it measures some articular intrinsic informations, in non-invasive manner (no using of intra-articular and intra-tendinous constraint gaugues) and can be perfectly integrated in a classical equine locomotor analysis. [less ▲]

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See detailÉtude cartographique et projet de restauration sur une rivière rectifiée, l’Eau Blanche
Peeters, Alexandre ULg; Verniers, Gisèle; Hallot, Eric ULg et al

Conference (2010, October 04)

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See detailEtude chémo-écologique et comportementale du parasitoïde, Nasonia vitripennis Walker (Hym., Pteromalidae), en vue de son utilisation comme biodétecteur en entomologie forensique
Frederickx, Christine ULg

Doctoral thesis (2012)

Most reports published in the field of forensic entomology are focused on Diptera, mostly on Calliphoridae. However, Hymenoptera are part of the entomofaunal colonisation of a dead body. Despite their ... [more ▼]

Most reports published in the field of forensic entomology are focused on Diptera, mostly on Calliphoridae. However, Hymenoptera are part of the entomofaunal colonisation of a dead body. Despite their significant presence in crime scenes, parasitoids are largely ignored due to their small size and the paucity of biological and behavioral information available in the ecosystem of corpse. The use of Hymenoptera parasitoids in forensic entomology can be relevant to many applications such as development of a biodectector. The objectives of this thesis were (1) to identify the Hymenoptera community parasitizing necrophagous Diptera, (2) to identify volatile organic compounds emitted by decaying process and by hosts which facilitate host-habitat and host location by female Nasonia vitripennis Walker (3) to evaluate the species N. vitripennis as biodectector of corpses. The faunistic study has identified five species of Hymenoptera in cadaver ecosystem. Alysia manducator was the most abundant Braconidae species. However, N. vitripennis was chosen as insect model; because over the last 50 years, this wasp has been intensely investigated in the subject of genetic, ecological and evolutionary research. A chemo-ecological approach, combining EAG and behavioral studies, was used on N. vitripennis with selected compounds from the decay process and their hosts. Firstly, we have demonstrated that host- habitat location and host location were dependent on the concentration of volatile organic compounds tested. In addition, dimethyldisulfide, a key component of decomposition and also released by Calliphora vicina Robineau-Desvoidy (Diptera, Calliphoridae) pupae, has a biological activity. Secondly, we have showed that rate of parasitism was based on the age of pupa, depth and substrate in which larvae burrow. This rate is the most important when pupae were six day-old, on the surface of soil and in a soil with a granulometry greater than 1mm. Moreover, N. vitripennis expanded our potential resource in biosensor used in forensic science. Females demonstrated a capacity for learning and memory. [less ▲]

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See detailEtude chimiotaxonomique dans les genres Macrotyloma, Dolichos et Pseudovigna
Dardenne, G. A.; Thonart, Philippe ULg; Otoul, E. et al

in Phytochemistry (1972), 12

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See detailEtude chimique de la graine de Simarouba glauca D.C. Détermination de la structure des triglycérides
Lognay, Georges ULg; Ergo, A.; Wathelet, Jean-Paul ULg et al

in Revue Française des Corps Gras (1981), 3

Une étude détatllée sur I'amande de la graine de Simarouba glauca D.C. est présentée. Cet arbuste tropical originarre d'Amérique Centrale est implanté depuis quelques années au Burundi. La graine est ... [more ▼]

Une étude détatllée sur I'amande de la graine de Simarouba glauca D.C. est présentée. Cet arbuste tropical originarre d'Amérique Centrale est implanté depuis quelques années au Burundi. La graine est analysée et deux modes d'extraction des lipides totaux sont testés. Les paramètres caractérisant la matière grasse sont déterminés, L'analyse des triglycérides et la détermination de leur structure sont entrcprises suivant les méthodes de calcul proposées par Van Der Wal et par Wathelet. Des pourcentages élevés en 00St - 000 - StOSt - POSt - OOP sont rencontrés et les principaux triglycérides sont du type mono-insaturé symétrique (SlS), di-insaturé asymetrique (SII) et tri-insaturé (III). [less ▲]

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See detailEtude chromatographique de substances volatiles : cas des sémiochimiques
Heuskin, Stéphanie ULg

Scientific conference (2008, December)

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See detailEtude chromatographique de substances volatiles : cas des sémiochimiques
Heuskin, Stéphanie ULg

Scientific conference (2010, November)

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See detailEtude chromatographique de substances volatiles : cas des sémiochimiques
Heuskin, Stéphanie ULg

Scientific conference (2009, November)

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See detailEtude chromatographique de substances volatiles : cas des sémiochimiques
Heuskin, Stéphanie ULg

Scientific conference (2007, October)

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See detailEtude chromatographique de substances volatiles: cas des sémiochimiques
Heuskin, Stéphanie ULg

Scientific conference (2009, November 10)

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See detailEtude cinématographique de la marche de l'hémiplégique : Intérêt de l'électrostimulation fonctionnelle
Vanderthommen, Marc ULg; Bauval, A.; Croisier, Jean-Louis ULg et al

in Actualités en Rééducation Fonctionnelle et Réadaptation, 20ème série (1995)

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See detailÉtude climatologique des irrégularités ionosphériques détectées à l'aide des GNSS
Wautelet, Gilles ULg

Master of advanced studies dissertation (2007)

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See detailEtude clinique comparative de l'effet de la prostaglandine F2alpha sur la rétention placentaire chez la vache
Hanzen, Christian ULg; Baudoux, Ch

in Annales de Médecine Vétérinaire (1985), 129

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See detailEtude clinique d’une dyade, régressant en fonctionnement borderline au niveau contextuel, individuel et familial, caractérisée par un passage à l’acte abusif d’ordre sexuel
Aubinet, Suzanne ULg; D'Amore, Salvatore ULg; Cancrini, Luigi

in Thérapie Familiale (2013), 2

This research is based on Luigi Cancrini’s theory of regression in borderline functioning which provides a structured and nuanced reflection on sexual abuse. It offers the possibility of establishing a ... [more ▼]

This research is based on Luigi Cancrini’s theory of regression in borderline functioning which provides a structured and nuanced reflection on sexual abuse. It offers the possibility of establishing a framework for observation and analysis of both synchronic and diachronic blendings; the behavioral characteristics proposed by the victims, perpetrators and their families; and the historical sense that can give them. It leads to the identification of the central link connecting the actors and their life contexts. We analyze a clinical situation with sexual abuse. The chosen dyad, composed by a 7 year-old-girl and a 13 ½ year-old-boy, was observed in vivo during hospitalization. Relevant behavioral, relational and historical components were compiled in an analytic scale based on Cancrini (2009) and Barudy (1997) writings. Similar psychopathological functioning among perpetrators, victims and families could thus be seen within this framework. The comparison of the systems reported similar family dynamics within the different subsystems. For these children, this results in the emergence of a specific behavioral repertory, typical of a borderline functioning, characterizing both the perpetrator and the aggressed: both are embedded in rigid supporting dyadic relational patterns and intense cleaved positions, which are also found within the various systems and the individuals within them. [less ▲]

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See detailL'etude clinique du mois Quel antihypertenseur en premiere intention? Resultats de l'etude ALLHAT.
Scheen, André ULg; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2003), 58(1), 47-52

Antihypertensive therapy is well established to reduce hypertension-related morbidity and mortality, but the optimal first-step therapy is still controversial. The "Antihypertensive and Lipid-Lowering ... [more ▼]

Antihypertensive therapy is well established to reduce hypertension-related morbidity and mortality, but the optimal first-step therapy is still controversial. The "Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial" (ALLHAT) should give such an answer. It is a randomised, double-blind, trial designed to determine whether treatment with either a calcium channel blocker or an angiotensin-converting enzyme inhibitor lowers the incidence of coronary heart disease (CHD) or other cardiovascular disease (CVD) events vs treatment with a diuretic. A total of 33,357 participants aged 55 years or older with mild to moderate hypertension and at least 1 other CHD risk factor were randomly assigned to receive chlorthalidone (12.5 to 25 mg/day; n = 15,255), amlodipine (2.5 to 10 mg/day; n = 9,048) or lisinopril (10 to 40 mg; n = 9,054). The primary outcome combined both fatal CHD and non-fatal myocardial infarction, analyzed by intent-to-treat. Secondary outcomes were all-causes mortality, stroke, combined CHD (primary outcome, coronary revascularization, or angina with hospitalization), and combined CVD (combined CHD, stroke, treated angina without hospitalization, heart failure and peripheral arterial disease). Chlorthalidone was slightly more effective in reducing systolic pressure while amlodipine reduced slightly more effectively diastolic blood pressure. After a mean follow up of 4.9 years, no differences were observed between the three treatments regarding both the primary outcome and the total mortality. Secondary outcomes were similar when comparing amlodipine vs chlorthalidone. A moderately higher 6-year incidence rate of clinically detected heart failure was observed with amlodipine, but without significant influence on mortality. For lisinopril vs chlorthalidone, lisinopril had slightly higher 6-year rates of combined CVD, stroke and heart failure. In conclusion, thiazide-type diuretics are superior in preventing one or more major forms of CVD and offer the advantage to be cheaper. They should be preferred for first-step antihypertensive therapy. However, to reach the recommended blood pressure target, most patients should receive a combination of antihypertensive compounds. Such a combination should always comprise a diuretic agent, in absence of contra-indications. [less ▲]

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See detailL’ÉTUDE CLINIQUE DU MOIS TECOS : confirmation de la sécurité cardiovasculaire de la sitagliptine
SCHEEN, André ULg; PAQUOT, Nicolas ULg

in Revue Médicale de Liège (2015), 70

Summary : The cardiovascular safety of sitagliptin has been evaluated in TECOS («Trial Evaluating Cardiovascular Outcomes with Sitagliptin»). TECOS recruited patients with type 2 diabetes and a history of ... [more ▼]

Summary : The cardiovascular safety of sitagliptin has been evaluated in TECOS («Trial Evaluating Cardiovascular Outcomes with Sitagliptin»). TECOS recruited patients with type 2 diabetes and a history of cardiovascular disease who received, as add-on to their usual therapy, either sitagliptin (n = 7.257) or placebo (n = 7.266), with a median follow-up of 3 years. The primary cardiovascular outcome was a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. Sitagliptin was noninferior to placebo for the primary composite cardiovascular outcome (hazard ratio, 0.98; 95 % confidence interval, 0.88 to 1.09; P<0.001). Rates of hospitalization for heart failure did not differ between the two groups (hazard ratio, 1.00; 95 % CI, 0.83 to 1.20; P=0.98). The cardiovascular safety of sitagliptin, which was already shown in meta-analyses of phase II-III randomised controlled trials and in observational cohort studies in real life, is now confirmed in the landmark prospective cardiovascular outcome study TECOS. [less ▲]

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