Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailGehlenite from three occurrences of high-temperature skarns, Romania: new mineralogical data
Marincea, Stefan ULg; Dumitras, Delia; Ghinet, C. et al

in Canadian Mineralogist (2011), 49

Detailed reference viewed: 32 (2 ULg)
See detailHet geïntegreerde contrastieve onderzoeksdesign onder de loep
Hiligsmann, Philippe; Rasier, Laurent ULg

in Rasier, Laurent; Van Heuven, Vincent; Defrancq, Bart (Eds.) et al Nederlands in het perspectief van uitspraakverwerving en contrastieve taalkunde (2011)

Detailed reference viewed: 25 (7 ULg)
Peer Reviewed
See detailA gel retardation assay system for studying protein binding to simple repetitive DNA sequences.
Maueler, W.; Muller, Marc ULg; Kohne, A. C. et al

in Electrophoresis (1992), 13(1-2), 7-10

Simple repetitive DNA sequences have been regarded as mere "junk" present in all eukaryotic genomes. In fact, mixed simple repeat (gt)n(ga)m sequences are present in major histocompatibility complex MHC ... [more ▼]

Simple repetitive DNA sequences have been regarded as mere "junk" present in all eukaryotic genomes. In fact, mixed simple repeat (gt)n(ga)m sequences are present in major histocompatibility complex MHC-DRB genes for long evolutionary times, including such distant animals as artiodactyla and man. We describe herein an unsophisticated method which reveals that at least certain simple repetitive (gt)n(ga)m sequences bind nuclear proteins and show characteristics of a specific DNA-protein interaction via gel retardation. [less ▲]

Detailed reference viewed: 36 (1 ULg)
Full Text
Peer Reviewed
See detailGel-casted porous Al2O3 ceramics by use of natural fibres as pore developers
Gaydardzhiev, Stoyan ULg; Gusovius, Hans; Wilker, Viola et al

in Journal of Porous Materials (2007)

Detailed reference viewed: 56 (21 ULg)
Full Text
Peer Reviewed
See detailGelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy.
Polette, M.; Gilbert, N.; Stas, I. et al

in Virchows Archiv : An International Journal of Pathology (1994), 424

The gelatinase A (72 kDa type IV collagenase) is a matrix metallo-proteinase which degrades basement membrane collagens. Various studies emphasize its role in stromal invasion of cancers, but there is ... [more ▼]

The gelatinase A (72 kDa type IV collagenase) is a matrix metallo-proteinase which degrades basement membrane collagens. Various studies emphasize its role in stromal invasion of cancers, but there is some controversy about its origin. Gelatinase A was localized by immunohistochemistry using confocal microscopy in 15 human mammary carcinomas. In addition, the cells responsible for the synthesis of this enzyme were detected by in situ hybridization. Most invasive and non-invasive tumour cells were labelled by immunohistochemistry. Of particular interest was the pattern observed in some pre-invasive areas. Gelatinase A was found in fibroblasts in close contact with pre-invasive tumour clusters. Confocal observation allowed a more precise localization of gelatinase A to the periphery of tumour clusters along the basement membranes and in peritumour fibroblasts. The malignant epithelial cells were negative by immunohistochemistry in these areas. By in situ hybridization, mRNAs encoding gelatinase A were detected only in fibroblasts in close contact with pre-invasive and well differentiated tumour clusters. These findings support the hypothesis that peritumour fibroblasts produce gelatinase A and that breast cancer cells may bind this enzyme to their cell surface and/or internalize it. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailGeldanamycin inhibits tyrosine phosphorylation-dependent NF-kB activation
Crèvecoeur, Julie ULg; Piette, Jacques ULg; Gloire, Geoffrey ULg

in Biochemical Pharmacology (2008), 75(11), 2183-2191

Hsp90 is a protein chaperone regulating the stability and activity of many signalling molecules. The requirement of Hsp90 activity in the NF-κB pathway has been recently reported by several authors using ... [more ▼]

Hsp90 is a protein chaperone regulating the stability and activity of many signalling molecules. The requirement of Hsp90 activity in the NF-κB pathway has been recently reported by several authors using the Hsp90 ATPase inhibitor Geldanamycin (GA), an anti-tumour drug. Hsp90 inhibition blocks the synthesis and activation of the IKK complex, the major kinases complex responsible for IκBα phosphorylation on serine 32 and 36, a key step for its degradation and the nuclear translocation of NF-κB. However, the effect of GA on other IκBα kinases, including tyrosine kinases, is unknown. In the present study, we investigated the effect of GA on NF-κB activation induced by sodium pervanadate (PV), a tyrosine phosphatase inhibitor triggering c-Src-mediated tyrosine phosphorylation of IκBα. We reporte for the first time that GA inhibits PV-induced IκBα tyrosine phosphorylation and degradation. Using an in vitro kinase assay, we demonstrated that GA inhibits the activity of c-Src as an IκBα tyrosine kinase, but not its cellular expression. As a result, GA blocked PV-induced NF-κB DNA binding activity on an exogenous κB element and on the endogenous iκbα promoter, thereby inhibiting IκBα transcription. Finally, we demonstrated that, despite NF-κB inhibition, pre-treatment with GA does not potentiate PV-induced apoptosis. We conclude that c-Src requires Hsp90 for its tyrosine kinase activity, and its inhibition by GA blocks c-Src-dependent signalling pathways, such as NF-κB activation induced by sodium pervanadate. The effect of GA on PV-induced apoptosis is discussed in the light of recent publications in the literature. [less ▲]

Detailed reference viewed: 76 (8 ULg)
See detailGellert und die empfindsame Aufklärung : Vermittlungs-, Austausch- und Rezeptionsprozesse in Wissenschaft, Kunst und Kultur.
Viehöver, Vera ULg; Schönborn, Sibylle

Book published by Erich Schmidt (2009)

Detailed reference viewed: 31 (7 ULg)
Full Text
Peer Reviewed
See detailGellerts Spur in Leopold Mozarts 'Versuch einer gründlichen Violinschule'
Viehöver, Vera ULg

in Viehöver, Vera; Schönborn, Sibylle (Eds.) Gellert und die empfindsame Aufklärung : Vermittlungs-, Austausch- und Rezeptionsprozesse um 1750 (2009)

Detailed reference viewed: 30 (7 ULg)
Peer Reviewed
See detailGelling properties of whey proteins after enzymic fat hydrolysis
Blecker, Christophe ULg; Paquot, Michel ULg; Deroanne, C.

in Journal of Food Science (2000), 65(4), 561-563

The effect of residual fat hydrolysis upon the gelation of whey protein concentrate (WPC) was studied. Gelling properties of a commercial WPC and lipase-treated WPC were evaluated on the basis of least ... [more ▼]

The effect of residual fat hydrolysis upon the gelation of whey protein concentrate (WPC) was studied. Gelling properties of a commercial WPC and lipase-treated WPC were evaluated on the basis of least concentration endpoint gelation, penetration test, texture profile analysis and water-holding capacity. Heat treatment of lipase-treated WPC led to gels with the highest hardness, springiness, cohesiveness and water retention. Such transformed WPC could be advantageously used to help improve texture in formulated meat, bakery, and confectionery products. [less ▲]

Detailed reference viewed: 17 (5 ULg)
See detailDas Gelobte Land: Erez Israel von der Antike bis zur Gegenwart in Quellen und Darstellungen
Pontzen, Alexandra ULg; Stähler, Axel

Book published by rowohlt enzyklopädie (2003)

Die Auseinandersetzung um die Existenz-Bedingungen und die territoriale Ausdehnung des Staates Israel steht seit Jahrzehnten im Zentrum des Nahost-Konflikts. Grundlegend für die Landfrage ist die ... [more ▼]

Die Auseinandersetzung um die Existenz-Bedingungen und die territoriale Ausdehnung des Staates Israel steht seit Jahrzehnten im Zentrum des Nahost-Konflikts. Grundlegend für die Landfrage ist die Tradition von "Erez Israel", dem "Land Israel" als gottbestimmter, legitimierter Heimat der Juden. Auf diese für Religion, Geschichte und Kultur des Judentums zentrale Tradition beruft sich auch der heutige jüdische Staat. Er versteht sich als Erfüllung des Traums von der "Erlösung Israels". Die Proklamationsurkunde von 1948 erklärt das "natürliche und historische Recht des jüdischen Volkes", den jüdischen Staat "auf den Boden des Heimatlandes" zu gründen: in Palästina. Textzeugnisse unterschiedlicher Herkunft und Gattung aus der Zeit zwischen 600 v. Chr. bis 2000 n. Chr. dokumentieren die Idee von verheißenem Land und die Kopplung von Religion und Land in Tradition von "Erez Israel". Kommentare und Erläuterungen von Wissenschaftlern verschiedener Disziplinen liefern Hintergrundinformationen und einen historischen Überblick. Sie ermöglichen es dem allgemein-politisch wie dem fachwissenschaftlich interessierten Leser, sich ein eigenes Urteil zu bilden. [less ▲]

Detailed reference viewed: 51 (0 ULg)
See detailDas „Gelobte Land“ von den Anfängen bis zur Gegenwart – ein Überblick
Pontzen, Alexandra ULg; Bertrams, Oliver; Stähler, Axel

Part of book (2003)

Detailed reference viewed: 52 (2 ULg)
See detailLa "Geltung" de Lotze et l'a priori matériel
Dewalque, Arnaud ULg

Conference (2011, December 16)

Je me propose de réévaluer un certain aspect de l’héritage de Lotze, à savoir sa théorie de la validité (Geltung). En m’inspirant notamment d’une remarque de Georg Misch, qui fut l’éditeur de la troisième ... [more ▼]

Je me propose de réévaluer un certain aspect de l’héritage de Lotze, à savoir sa théorie de la validité (Geltung). En m’inspirant notamment d’une remarque de Georg Misch, qui fut l’éditeur de la troisième édition du système de Lotze en 1912, et de certaines déclarations de Husserl, je défendrai la thèse suivante : la théorie lotzéenne de la validité appartient à une tradition qui se caractérise par la découverte de propositions aprioriques d’un certain genre, à savoir des relations of ideas (au sens de Hume), des lois aprioriques matérielles (au sens de Husserl) ou des axiomes objectifs, régionaux ou matériels (au sens de Stumpf). Ce que je voudrais suggérer, en un mot, c’est qu’il y a une connexion étroite entre le concept lotzéen de validité et la découverte de l’a priori matériel. [less ▲]

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailDe gemaskerde eeuw (Marita Mathijsen)
Steyaert, Kris ULg

in Neerlandica Extra Muros (2003), 41(3), 73-75

Detailed reference viewed: 24 (1 ULg)
Full Text
See detailGember: hoogwaardige anti-emeticum in de officinale praktijk
Angenot, Luc ULg

in Farma Sfeer (2014), 18(195), 30-31

Detailed reference viewed: 3 (0 ULg)
Full Text
See detailGembloux : une bibliothèque universitaire au cœur du monde
Pochet, Bernard ULg

in Lectures : La Revue des Bibliothèques (2006), 146

Cet article est le premier d'une série d'articles, sur les bibliothèques universitaires de la Communauté française de Belgique, publiés dans la revue Lecture

Detailed reference viewed: 105 (27 ULg)
Full Text
See detailGembloux Agricultural University : ICT learning
Colaux, Catherine ULg; Claustriaux, Jean-Jacques ULg

Scientific conference (2009)

Etat des lieux des outils TICE de la FUSAGx.

Detailed reference viewed: 24 (11 ULg)
Full Text
See detailGembloux: des poissons pour faire pousser des salades
Jijakli, Haissam ULg

Article for general public (2013)

Detailed reference viewed: 16 (6 ULg)
Full Text
Peer Reviewed
See detailGemvid, an Open Source, Modular, Automated Activity Recording System for Rats Using Digital Video
Poirrier, Jean-Etienne; Poirrier, Laurent; Leprince, Pierre ULg et al

in Journal of Circadian Rhythms (2006), 4

BACKGROUND: Measurement of locomotor activity is a valuable tool for analysing factors influencing behaviour and for investigating brain function. Several methods have been described in the literature for ... [more ▼]

BACKGROUND: Measurement of locomotor activity is a valuable tool for analysing factors influencing behaviour and for investigating brain function. Several methods have been described in the literature for measuring the amount of animal movement but most are flawed or expensive. Here, we describe an open source, modular, low-cost, user-friendly, highly sensitive, non-invasive system that records all the movements of a rat in its cage. METHODS: Our activity monitoring system quantifies overall free movements of rodents without any markers, using a commercially available CCTV and a newly designed motion detection software developed on a GNU/Linux-operating computer. The operating principle is that the amount of overall movement of an object can be expressed by the difference in total area occupied by the object in two consecutive picture frames. The application is based on software modules that allow the system to be used in a high-throughput workflow. Documentation, example files, source code and binary files can be freely downloaded from the project website at http://bioinformatics.org/gemvid/. RESULTS: In a series of experiments with objects of pre-defined oscillation frequencies and movements, we documented the sensitivity, reproducibility and stability of our system. We also compared data obtained with our system and data obtained with an Actiwatch device. Finally, to validate the system, results obtained from the automated observation of 6 rats during 7 days in a regular light cycle are presented and are accompanied by a stability test. The validity of this system is further demonstrated through the observation of 2 rats in constant dark conditions that displayed the expected free running of their circadian rhythm. CONCLUSION: The present study describes a system that relies on video frame differences to automatically quantify overall free movements of a rodent without any markers. It allows the monitoring of rats in their own environment for an extended period of time. By using a low-cost, open source hardware/software solution, laboratories can greatly simplify their data acquisition and analysis pipelines and improve their workload. [less ▲]

Detailed reference viewed: 78 (8 ULg)
Full Text
Peer Reviewed
See detailGender and age at drinking onset affect voluntary alcohol consumption but neither the alcohol deprivation effect nor the response to stress in mice.
Tambour, Sophie ULg; Brown, Lauren L; Crabbe, John C

in Alcoholism, Clinical & Experimental Research (2008), 32(12), 2100-6

BACKGROUND: Epidemiological studies suggest that initiation of alcohol drinking at an early age is associated with an increased risk of developing an alcohol use disorder later in life. Nevertheless ... [more ▼]

BACKGROUND: Epidemiological studies suggest that initiation of alcohol drinking at an early age is associated with an increased risk of developing an alcohol use disorder later in life. Nevertheless, relatively few studies using animal models have investigated the relationship between age of onset of drinking and ethanol drinking patterns in adulthood. Besides age at drinking onset, other factors such as gender could also affect the pattern of development of alcohol consumption. In rodents, many studies have shown that females drink more than males. However, even if it is assumed that hormonal changes occurring at puberty could explain these differences, only one study performed in rats has investigated the emergence of sex-specific alcohol drinking patterns in adolescence and the transition from adolescence to adulthood. The aim of the present study was to compare the acquisition of voluntary alcohol consumption, relapse-like drinking (the Alcohol Deprivation Effect-ADE) and stress-induced alcohol drinking in male and female outbred mice that acquired alcohol consumption during adolescence or adulthood. METHODS: Separate groups of naive female and male WSC-1 mice aged +/- 28 days (adolescents) or +/-70 days (adults) were given ad libitum access to water and 6% ethanol solution for 8 weeks (1st to 8th week) before undergoing a 2-week deprivation phase (9th and 10th week). After the deprivation period, 2-bottle preference testing (ethanol vs. water) resumed for 3 weeks (11th to 13th). During the 13th week, all animals were subjected to restraint stress for 2 consecutive days. RESULTS: Over the entire time course of the experiment, ethanol intake and preference increased in females (both adults and adolescents). Adolescent animals (both females and males) showed a transient increase in alcohol consumption and preference compared to adults. However, by the end of continuous alcohol exposure (when all mice were adults), ethanol intake was not affected by age at drinking onset. A deprivation phase was followed by a rise in ethanol intake (ADE) that was not affected by sex or age. Finally, stress did not alter alcohol self-administration either during or after its occurrence. CONCLUSIONS: Emergence of greater alcohol consumption in adult females does not seem to be limited to a specific developmental period (i.e., puberty). Age of voluntary drinking onset (adolescence vs. adulthood) does not affect eventual alcohol intake in adult WSC-1 mice and does not modify the transient increase in ethanol consumption after alcohol deprivation. [less ▲]

Detailed reference viewed: 24 (2 ULg)