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See detailA generic approach for solving nonlinear-discrete security-constrained power flow problems in large-scale systems
Platbrood, Ludovic; Capitanescu, Florin; Crisciu, Horia et al

in IEEE Transactions on Power Systems (in press)

This paper proves the practicality of an iterative algorithm for solving realistic large-scale SCOPF problems. This algorithm is based on the combination of a contingency filtering scheme, used to ... [more ▼]

This paper proves the practicality of an iterative algorithm for solving realistic large-scale SCOPF problems. This algorithm is based on the combination of a contingency filtering scheme, used to identify the binding contingencies at the optimum, and a network compression method, used to reduce the complexity of the post-contingency models included in the SCOPF formulation. We show that by combining these two complementary ideas, it is possible to solve in a reasonable time SCOPF problems on large power system models with a large number of contingencies. Unlike most results reported for large-scale SCOPF problems, our algorithm uses a non-linear AC network model in both pre-contingency and post-contingency states, optimizes both active/reactive powers flows jointly, and treats the discrete variables. The proposed algorithm is implemented with state-of-the-art solvers and applied to two systems: a national grid with 2563 buses and 1297 contingencies, and a model of the European transmission network with 9241 buses and 12000 contingencies. [less ▲]

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See detailA generic chemical platform for molecular recognition and stimuli-responsive probes based on scanning probe microscopy
Cecchet, Francesca; Lussis, Perrine ULg; Jérôme, Christine ULg et al

in Small : Nano Micro (2008), 4(8), 1101-1104

The grafting of poly-N-succinimidyl acrylate from scanning probe microscopy tips is shown to be a robust platform for the very easy elaboration of versatile probes with sensor capabilities and tunable ... [more ▼]

The grafting of poly-N-succinimidyl acrylate from scanning probe microscopy tips is shown to be a robust platform for the very easy elaboration of versatile probes with sensor capabilities and tunable properties. The modified tips can be easily postfunctionalized for single-molecule recognition of host-guest and ligand-receptor systems and for the design of smart probes that are thermo- and pH-responsive. [less ▲]

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See detailA generic platform for SPM-based molecular recognition processes and stiluli-responsive probes
Gabriel, Sabine ULg; Jérôme, Christine ULg; Silva-Goncalves, Elsa et al

Poster (2006, May 18)

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See detailGeneric results in classes of ultradifferentiable functions
Esser, Céline ULg

in Journal of Mathematical Analysis & Applications (2014), 413(1), 378391

Let E be a Denjoy Carleman class of ultradifferentiable functions of Beurling type on the real line that strictly contains another class F of Roumieu type. We show that the set S of functions in E that ... [more ▼]

Let E be a Denjoy Carleman class of ultradifferentiable functions of Beurling type on the real line that strictly contains another class F of Roumieu type. We show that the set S of functions in E that are nowhere in the class F is large in the topological sense (it is residual), in the measure theoretic sense (it is prevalent), and that SU{0} contains an infinite dimensional linear subspace (it is lineable). Consequences for the Gevrey classes are given. Similar results are also obtained for classes of ultradifferentiable functions defined imposing conditions on the Fourier Laplace transform of the function. [less ▲]

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See detailGeneric results in Denjoy-Carleman classes
Esser, Céline ULg

Poster (2013, September 09)

Denjoy-Carleman classes are spaces of smooth functions which satisfy growth conditions on their derivatives. We distinguish the class of ultradi fferentiable functions of Roumieu type and the class of ... [more ▼]

Denjoy-Carleman classes are spaces of smooth functions which satisfy growth conditions on their derivatives. We distinguish the class of ultradi fferentiable functions of Roumieu type and the class of ultradi fferentiable functions of Beurling typ. Endowed with its natural topology, the Beurling class is a Fr échet space. In the poster, we give a condition to have the strict inclusion of a Roumieu class into aBeurling class. We obtain then generic results about the set of functions of a Beurling class which are nowhere in a Roumieu class. Those generic results are obtained from three di fferent points of view: using the Baire category theorem, the notion of prevalence and the notion of lineability. We also study the particular case of Gevrey classes. [less ▲]

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See detailA Generic Service Interface for Cloud Networks
Sifalakis, Manolis; Tschudin, Christian; Martin, Sylvain ULg et al

in Leymann, Frank; Ivanov, Ivan; van Sinderen, Marten (Eds.) CLOSER (2011, May 09)

Two major challenges for enabling the vision of cloud computing regard (a) the generic and multi-purpose access to (virtualised) resources, and (b) the flexible, dynamic, and on-demand composition of ... [more ▼]

Two major challenges for enabling the vision of cloud computing regard (a) the generic and multi-purpose access to (virtualised) resources, and (b) the flexible, dynamic, and on-demand composition of services from virtual resources; from the service level, all the way ``down'' to the lamda level. Both aspects require a respective flexibility and expressibility from the interfaces in-place, which is missing from the current static socket (and other) interfaces below the application level. In this position paper, we propose, explain and exemplify an alternative generic and universal resource interface (GRI) that borrows from object oriented design to enable properties such as polymorphic access, generic service composition, introspection and dynamic reconfigurability, of in-network resources, opening in this way the path for flexible creation of service clouds. [less ▲]

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See detailGeneric systems for the enantioseparation of basic drugs in NACE using single-isomer anionic CDs
Rousseau, Anne ULg; Gillotin, Florian; Chiap, Patrice ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (2011), 54

The enantioseparation of ten basic drugs was evaluated in NACE systems using heptakis(2-O-methyl-3-O-acetyl-6-O-sulfo)-β-CD (HMAS-β-CD). For this purpose, a D-optimal design with 21 experimental points ... [more ▼]

The enantioseparation of ten basic drugs was evaluated in NACE systems using heptakis(2-O-methyl-3-O-acetyl-6-O-sulfo)-β-CD (HMAS-β-CD). For this purpose, a D-optimal design with 21 experimental points was applied. Four antifungal agents (econazole, isoconazole, miconazole, sulconazole), three local anesthetics (bupivacaine, mepivacaine and prilocaine), two sympathomimetics (salbutamol and terbutaline) and one β-blocker (carvedilol) were selected as basic model analytes. The influence on the enantiomeric resolution of anionic CD and BGE anion concentrations as well as the BGE anion nature was investigated. For all studied analytes, the enantiomeric resolution was shown to be significantly influenced by the CD concentration. Based on the observed results, a generic NACE system was recommended, namely 20 mM HMAS-β-CD and 10 mM ammonium camphorSO3- in methanol acidified with 0.75 M formic acid. Moreover, this NACE system was compared to previous conditions with heptakis(2,3-di-O-methyl-6-O-sulfo)-β-CD (HDMS-β-CD) or heptakis(2,3-di-O-acetyl-6-O-sulfo)-β-CD (HDAS-β-CD). Finally, two generic systems using either HDAS-β-CD or HMAS-β-CD were proposed and evaluated for the enantioseparation of ketamine and norketamine after incubation of ketamine in phenobarbital-induced male rat liver microsomes systems. [less ▲]

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See detailLe générique de faux documentaire. Approche critique d'un incitant à la lucidité du spectateur.
Hamers, Jérémy ULg

Conference (2013, June 26)

Parallèlement aux multiples commentaires cinéphiliques que le générique suscite depuis plusieurs années, les travaux récents qui lui sont consacrés l’envisagent comme un objet d’étude esthétique ... [more ▼]

Parallèlement aux multiples commentaires cinéphiliques que le générique suscite depuis plusieurs années, les travaux récents qui lui sont consacrés l’envisagent comme un objet d’étude esthétique, narratologique ou sémiologique à part entière. Selon ces études, le générique est un objet fragmentaire (placé majoritairement à partir des années 1960 « sur » les images du début ou de la fin d’un film) voire autonome (on connaît les auteurs spécialisés en réalisation de génériques), marginal aussi (rarement au centre de l’œuvre ; le « générique-préface » de de Mourgues), frontalier encore (dans et hors du film, ou plutôt : à son orée), qui fait office d’ouverture ou de clôture hybride du film. Appartenant à la fois à l’univers de la fiction et à « un autre espace-temps, réel, celui de la production » (Moinereau), le générique de début plus particulièrement sert à « enclencher la diégèse » (de Mourgues) mais aussi à lui résister. « [S]orte de zone franche entre le monde de la réalité et celui de la fiction » (Metz), il est une passerelle, une aide au passage, au basculement dans la fiction. En tant que point pivot bâtard, le générique de début – et non pas « du début », appellation qui sous-entendrait l’appartenance exclusive à un seul lieu –, joue en effet sur deux registres. D’une part il affiche la ou les paternités bien réelles de l’œuvre (jusqu’au début des années 1910 il ne satisfait bien souvent qu’à cette seule obligation légale) et leur rend hommage (graphismes et durées différenciées), ou, dans ses versions les plus sophistiquées, offre au cinéphile (auto-)références et private jokes qui établissent entre le spectateur et l’auteur réel une complicité néanmoins non fatale pour le récit de fiction. D’autre part il aide le spectateur à s’abandonner à l’illusion de la fiction qui doit « mentir sur ses conditions de production » (Comolli) et dont le générique est pourtant le premier symptôme. En somme, le générique de début n’est donc pas seulement hybride par son lieu, mais aussi en raison de sa fonction quasi paradoxale : il établit avec le spectateur un lien a priori adiégétique dont la fonction première est précisément de faciliter son entrée dans la diégèse. Compte tenu de l’intérêt particulier que ces études accordent à la nature hybride du générique, il n’est pas étonnant que les travaux auxquels nous nous référons ici concernent exclusivement des films de fiction. Car, à l’inverse, dans le cas du cinéma documentaire, l’ambivalence inhérente à ce « commutateur de diégèse » (Gardies) est, en principe, inexistante étant donné que le générique d’un film non-fictionnel renvoie le spectateur à un univers « uniquement » réel, commun à l’ensemble du discours filmique. Dans cette perspective, il ne sert donc a priori qu’à inaugurer un contrat spectatoriel ou à poser les fondements d’une convention de lecture qui s’épanouira et développera sa pleine puissance dans le film (installation du principal médiateur, authentification de l’énonciateur, etc.). En documentaire, pas de conflit donc entre un espace-temps « adiégétique » et le film, entre la marge et le texte, car tous deux convoquent des éléments appartenant in fine au même registre, celui du réel. C’est en substance ce que suggère l’approche sémio-pragmatique du documentaire en envisageant le générique de début comme le lieu dans lequel un « je-origine réel » (Odin), par le biais de médiations institutionnelles ou non, prend ses quartiers dans le texte, ouvrant ainsi la voie à une « lecture documentarisante » incontestée dans la suite du film. Les paradigmes trop rapidement évoqués ici révèlent leurs limites dès lors qu’on les confronte à quelques sous-genres particulièrement pratiqués et populaires aujourd’hui tels que le faux documentaire, le docufiction, le mockumentary et le programme de télé-réalité. Se jouant précisément d’un contrat de lecture unilatéral et libre de tout malentendu, ces sous-genres documentaires brouillent la binarité posée par l’approche sémio-pragmatique (« documentarisant » vs « fictionalisant »). Notre analyse de quelques génériques, prégénériques et séquences d’annonce de faux documentaires, de mockumentaries et d’émissions de télé-réalité nous amène à redéfinir le contrat de lecture et les conventions qui y sont liées, propres au cinéma et à la télévision de non-fiction. Ces génériques ne contribuent pas à l’identification par le spectateur d’un énonciateur considéré comme réel (par jeu ou par conviction), mais établissent un nouvel accord tacite et flou entre un auteur reconnu comme fictif (ou ses avatars particulièrement nombreux dans le cas du mockumentary et de la télé-réalité) et le spectateur. Ce nouvel accord vise en réalité à produire l’adhésion forcée d’un spectateur qui pourtant sait qu’il n’est pas dupe, ou croit le savoir. Dans ce sens, le générique apparaît alors comme un lieu crucial pour toute analyse critique du discours non fictionnel : un lieu qui conteste l’authenticité de l’énonciateur et qui nie le crédit accordé au médiateur documentaire, pour offrir au public l’illusion de sa lucidité et le pousser ensuite vers une adhésion sans réserve à un jeu de réel. En somme, une étape indispensable à la constitution d’une crédulité paradoxale du spectateur. [less ▲]

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See detailLe générique de faux documentaire. Un incitant à la lucidité paradoxale du spectateur.
Hamers, Jérémy ULg

in Saint-Amand, Denis; Dozo, Björn-Olav; Luneau, Marie-Pier (Eds.) Jeux et enjeux de la préface (in press)

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See detailLes génériques d’antibiotiques : une fausse bonne idée ?
Van Hees, Thierry ULg

Scientific conference (2013, May 07)

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See detailThe Generosity of the Welfare State Towards the Elderly
Lefebvre, Mathieu ULg; Pestieau, Pierre ULg

in Empirica (2006)

This paper distinguishes among three types of generosity of social security systems: average generosity, generosity towards early retirement and generosity towards the poor. On the basis of theoretical ... [more ▼]

This paper distinguishes among three types of generosity of social security systems: average generosity, generosity towards early retirement and generosity towards the poor. On the basis of theoretical predictions, it examines the statistical correlations among those types of generosity for 14 OECD countries over the period 1985-2000. It also shows how they have evolved over time and tries to relate this evolution to the process of economic integration. There are three main findings, the first one being a positive relation between average social security spending and poverty alleviation. There is the negative relation between average spending and inequality reduction. Finally, over the period 1985-95 one sees that poverty alleviation increases on average, but to a degree that decreases with economic openness. [less ▲]

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See detailGenes causing pituitary adenomas
Beckers, Albert ULg

Scientific conference (2012, February 04)

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See detailLes gènes codant pour les facteurs de croissance
Portetelle, Daniel ULg; Burny Arsène; Kettmann, Richard ULg et al

in Renaville, Robert; Burny, Arsène (Eds.) Biotechnologie en sélection animale (1989)

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See detailGenes for growth hormone, chorionic somatommammotropin, and growth hormones-like gene on chromosome 17 in humans
Owerbach, D.; Rutter, W. J.; Martial, Joseph ULg et al

in Science (1980), 209(4453), 289-92

The human genes for growth hormone (GH), chorionic somatomammotropin (CSH), and a third growth hormone-like gene (GHL) have been located on chromosome 17 in humans. DNA fragments of 2.6, 2.8, and 9.5 ... [more ▼]

The human genes for growth hormone (GH), chorionic somatomammotropin (CSH), and a third growth hormone-like gene (GHL) have been located on chromosome 17 in humans. DNA fragments of 2.6, 2.8, and 9.5 kilobase pairs containing GH, CSH, and GHL, respectively, were identified in human genomic DNA, and a 7.5-kilobase DNA fragment related to growth hormone DNA sequences was found in mouse cells. In somatic hybrids of human and mouse cells containing reduced numbers of human chromosomes, but a normal complement of mouse chromosomes, the mouse, 7.5-kolobase DNA fragment was always present, whereas the 2.6-, 2.8-, and 9.5-kilobase human fragments were present only when human chromosome 17 was also present. [less ▲]

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See detailGenes for rare idiopathic generalized epilepsies: BFNC.
Singh, N.; Charlier, Carole ULg; Peiffer, A. et al

in Advances in neurology (1999), 79

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See detailGènes impliqués dans l'apoptose prostatique provoquée par un déficit androgénique
Bruyninx, Marc; Cornet, Anne ULg; Hennuy, Benoît ULg et al

in Medecine Sciences : M/S (1998), 14(5), 572-579

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See detailGenes involved in Phaseolus embryogenesis
Silué, S.; Jacquemin, J. M.; Baudoin, Jean-Pierre ULg

in Genes, Genomes and Genomics (2007), 1(2), 180-192

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See detailGenes involved in tumor invasion and metastasis are differentially modulated by estradiol and progestin in human breast-cancer cells.
van den Brule, F. A.; Engel, J.; Stetler-Stevenson, W. G. et al

in International Journal of Cancer = Journal International du Cancer (1992), 52(4), 653-7

Invasion of basement membranes by cancer cells is a critical step in metastasis, which requires the coordinated expression of specific genes such as laminin receptors and metalloproteinases. Estradiol and ... [more ▼]

Invasion of basement membranes by cancer cells is a critical step in metastasis, which requires the coordinated expression of specific genes such as laminin receptors and metalloproteinases. Estradiol and progesterone modulate the clinical progression of steroid-sensitive breast cancers; however, little is known about the molecular regulation of the invasive phenotype by these hormones. We therefore examined the effects of 10 nM estradiol and/or 10 nM progestin R5020 on the expression of 2 non-integrin laminin binding proteins, the 67-kDa laminin receptor (67LR) and HLBP31 as well as the 72-kDa type-IV collagenase (MMP-2) and its inhibitor, TIMP-2, in steroid-receptor-positive (T47D and MCF-7) and -negative (MDA-MB 231) human breast-cancer cells. The relative steady-state level of 67LR mRNA was increased 2- to 3-fold by estradiol in both MCF-7 (p < 0.001) and T47D (p < 0.001) cells, also by R5020, alone or in combination with estradiol, in T47D cells (p < 0.001) and to a much less extent in MCF-7 cells. HLBP31 mRNA and protein levels were increased 2- to 3-fold (p < 0.001) by R5020 alone or in combination with estradiol, but not by estradiol alone. None of the steroid treatments affected the expression or activity of MMP-2. Interestingly, however, TIMP-2 mRNA levels and protein expression in MCF-7 and T47D cells were 50% down-regulated (p < 0.001) by treatment with R5020 or R5020 plus estradiol, but not by treatment with estradiol alone. None of these genes were modulated in steroid-independent MDA-MB231 cells. The data suggest that estradiol and progesterone might act as coordinators regulating specific genes in the steroid-sensitive breast-cancer cell, leading to the acquisition of the metastatic phenotype. [less ▲]

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See detailGenes upregulated during castration-induced rat prostatic apoptosis: cloning and characterization of new cDNAs.
Bruyninx, M.; Ammar, H.; Reiter, E. et al

in BJU International (2000), 85(9), 1134-42

OBJECTIVE: To isolate new cDNAs corresponding to genes whose expression is increased during castration-induced rat prostate apoptosis. MATERIALS AND METHODS: Differential display of mRNAs from 3-day ... [more ▼]

OBJECTIVE: To isolate new cDNAs corresponding to genes whose expression is increased during castration-induced rat prostate apoptosis. MATERIALS AND METHODS: Differential display of mRNAs from 3-day castrated and normal rat ventral prostates was used to identify differentially expressed clones. Northern blots were hybridized to confirm the positive regulation of the candidates and to follow the change in their expression in the involuting rat prostate, and in thymocytes of dexamethazone-treated rats. RESULTS: Five cDNAs were cloned: one encoding ribosomal protein L7, one coding for the insulin-like growth factor binding protein-3 (IGFBP-3), and three whose products are unknown. After castration, all five genes had expression kinetics that closely paralleled the proportion of prostatic epithelial cells undergoing apoptosis. The gene encoding L7 and two of the unknown genes were also upregulated in glucocorticoid-induced programmed death in thymocytes. In addition to the IGFBP-3 gene, those coding for proteins IGFBP-4, -5 and -6 were also overexpressed in the involuting prostate of androgen-deprived rats. CONCLUSION: Five new genes were identified that are up-regulated during castration-induced rat prostate apoptosis, three of which are potentially involved in the common intracellular pathway leading to programmed cell death. [less ▲]

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