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See detailEFSA's scientific activities and achievements on the risk assessment of genetically modified organisms (GMOs) during its first decade of existence: looking back and ahead.
Devos, Yann; Aguilera, Jaime; Diveki, Zoltan et al

in Transgenic research (2014), 23(1), 1-25

Genetically modified organisms (GMOs) and derived food and feed products are subject to a risk analysis and regulatory approval before they can enter the market in the European Union (EU). In this risk ... [more ▼]

Genetically modified organisms (GMOs) and derived food and feed products are subject to a risk analysis and regulatory approval before they can enter the market in the European Union (EU). In this risk analysis process, the role of the European Food Safety Authority (EFSA), which was created in 2002 in response to multiple food crises, is to independently assess and provide scientific advice to risk managers on any possible risks that the use of GMOs may pose to human and animal health and the environment. EFSA's scientific advice is elaborated by its GMO Panel with the scientific support of several working groups and EFSA's GMO Unit. This review presents EFSA's scientific activities and highlights its achievements on the risk assessment of GMOs for the first 10 years of its existence. Since 2002, EFSA has issued 69 scientific opinions on genetically modified (GM) plant market registration applications, of which 62 for import and processing for food and feed uses, six for cultivation and one for the use of pollen (as or in food), and 19 scientific opinions on applications for marketing products made with GM microorganisms. Several guidelines for the risk assessment of GM plants, GM microorganisms and GM animals, as well as on specific issues such as post-market environmental monitoring (PMEM) were elaborated. EFSA also provided scientific advice upon request of the European Commission on safeguard clause and emergency measures invoked by EU Member States, annual PMEM reports, the potential risks of new biotechnology-based plant breeding techniques, evaluations of previously assessed GMOs in the light of new scientific publications, and the use of antibiotic resistance marker genes in GM plants. Future challenges relevant to the risk assessment of GMOs are discussed. EFSA's risk assessments of GMO applications ensure that data are analysed and presented in a way that facilitates scientifically sound decisions that protect human and animal health and the environment. [less ▲]

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See detailEf®cacy of background GABA uptake in rat hippocampal slices
Frahm, Christiane; Engel, Dominique ULg; Draguhn, Andreas

in Neuroreport (2001), 12(8), 1593-1596

GABA uptake is crucial for the termination of inhibitory synaptic events. In addition, GABA transporters may also control the level of diffusely distributed GABA in the extracellular space. We analysed ... [more ▼]

GABA uptake is crucial for the termination of inhibitory synaptic events. In addition, GABA transporters may also control the level of diffusely distributed GABA in the extracellular space. We analysed this function by superfusing rat hippocampal slices with different concentrations of GABA. Whole-cell patch clamp recordings of CA1 pyramidal cells revealed small increases in chloride conductance at 5-10 microM GABA which increased dramatically upon addition of the GABA uptake blocker tiagabine. Tiagabine alone induced a significant chloride conductance indicating that spontaneous release of GABA in hippocampal slices is neutralized by GAT-1, the main hippocampal GABA transporter. Thus, GAT-1 clears the extracellular space in the hippocampus from diffusely distributed GABA with high efficacy. [less ▲]

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See detailAn EG-VEGF-dependent decrease in homeobox gene NKX3.1 contributes to cytotrophoblast dysfunction: a possible mechanism in human fetal growth restriction
Murthi, P; Brouillet, S; Pratt, A et al

in Molecular Medicine (2015)

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See detailEG_Vergabregeln im ÖPNV : Stand und Perspektive
Partsch, Philippe-Emmanuel ULg

in Der Nahverkehr (2008)

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See detailL'égalité de genre à l'ULg
Cornet, Annie ULg

Scientific conference (2016, March)

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See detailL'égalité des chances : slogan ou réalité ?
de Landsheere, Gilbert ULg

in Socialisme (1981), 28

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See detailEgalité des chances et cohésion sociale
Delruelle, Edouard ULg

Conference given outside the academic context (2011)

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See detailL'égalité des créanciers: du principe à l'incantation?
Georges, Frédéric ULg

in A.E.D.B.F. (Ed.) Banque et insolvabilité (2007)

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See detailL'égalité en droit social
François, Lucien ULg

in Centre de philosophie du droit de l'Université Libre de Bruxelles (Ed.) L'Egalité. Volume V. (1977)

Labour law entertains an ambiguous relationship with the value "Equality" because in its name labour law creates inequalities - Le droit du travail entretient un rapport ambigu avec la valeur Egalité car ... [more ▼]

Labour law entertains an ambiguous relationship with the value "Equality" because in its name labour law creates inequalities - Le droit du travail entretient un rapport ambigu avec la valeur Egalité car il crée en son nom des inégalités [less ▲]

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See detailEgalité et émancipation : enjeux politiques de l'éducation à la philosophie
Herla, Anne ULg

Article for general public (2009)

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See detailL'égalité et le droit commercial: un rapport à géométrie variable
Thirion, Nicolas ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

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See detailEgalité filles/garçons à travers un état des lieux en Fédération Wallonie-Bruxelles
Demeuse, Marc; Lafontaine, Dominique ULg

Scientific conference (2016, November 19)

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See detailEgalité hommes-femmes: gender mainstreaming et genderbudgeting
Cornet, Annie ULg

Conference (2013, August)

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See detailEgalité professionnelle Femmes-Hommes:quels enjeux pour la GRH en Afrique sub-saharienne
Cornet, Annie ULg

Conference given outside the academic context (2016)

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See detailEGb 761 protects liver mitochondria against injury induced by in vitro anoxia/reoxygenation.
Du, G.; Willet, K.; Mouithys-Mickalad, Ange ULg et al

in Free Radical Biology & Medicine (1999), 27

The present study investigated the protective effects of Ginkgo biloba extract (EGb 761) on rat liver mitochondrial damage induced by in vitro anoxia/reoxygenation. Anoxia/reoxygenation was known to ... [more ▼]

The present study investigated the protective effects of Ginkgo biloba extract (EGb 761) on rat liver mitochondrial damage induced by in vitro anoxia/reoxygenation. Anoxia/reoxygenation was known to impair respiratory activities and mitochondrial oxidative phosphorylation efficiency. ADP/O (2.57 +/- 0.11) decreased after anoxia/reoxygenation (1.75 +/- 0.09, p < .01), as well as state 3 and uncoupled respiration (-20%, p < .01), but state 4 respiration increased (p < .01). EGb 761 (50-200 microg/ml) had no effect on mitochondrial functions before anoxia, but had a specific dose-dependent protective effect after anoxia/reoxygenation. When mitochondria were incubated with 200 microg/ml EGb 761, they showed an increase in ADP/O (2.09 +/- 0.14, p < .05) and a decrease in state 4 respiration (-22%) after anoxia/reoxygenation. In EPR spin-trapping measurement, EGb 761 decreased the EPR signal of superoxide anion produced during reoxygenation. In conclusion, EGb 761 specially protects mitochondrial ATP synthesis against anoxia/reoxygenation injury by scavenging the superoxide anion generated by mitochondria [less ▲]

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See detailEGF amplifies the replacement of parvalbumin-expressing striatal interneurons after ischemia.
Teramoto, Tetsuyuki; Qiu, Jianhua; Plumier, Jean-Christophe ULg et al

in Journal of Clinical Investigation (2003), 111(8), 1125-32

EGF promotes proliferation and migration of stem/progenitor cells in the normal adult brain. The effect of epidermal growth factor on neurogenesis in ischemic brain is unknown, however. Here we show that ... [more ▼]

EGF promotes proliferation and migration of stem/progenitor cells in the normal adult brain. The effect of epidermal growth factor on neurogenesis in ischemic brain is unknown, however. Here we show that intraventricular administration of EGF and albumin augments 100-fold neuronal replacement in the injured adult mouse striatum after cerebral ischemia. Newly born immature neurons migrate into the ischemic lesion and differentiate into mature parvalbumin-expressing neurons, replacing more than 20% of the interneurons lost by 13 weeks after ischemia and representing 2% of the total BrdU-labeled cells. These data suggest that administration of EGF and albumin could be used to manipulate endogenous neurogenesis in the injured brain and to promote brain self-repair. [less ▲]

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