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See detailEquine Osteochondrosis and possible relation with plasma IGF-I levels
Verwilghen, Denis ULg

Master of advanced studies dissertation (2006)

Detailed reference viewed: 26 (6 ULg)
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See detailEquine Piroplasmosis in Belgium: a retrospective study.
Delguste, Catherine ULg; Mantran, A.; Sandersen, Charlotte ULg et al

Poster (2006, January)

Detailed reference viewed: 33 (4 ULg)
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See detailEquine Post Anaesthetic Myositis: Muscular Post Ischaemic Hyperaemia Measured by Laser Doppler Flowmetry
Serteyn, Didier ULg; Lavergne, L.; Coppens, P. et al

in Veterinary Record : Journal of the British Veterinary Association (1988), 123(5), 126-8

Measurements of muscular microcirculation in horses anaesthetised with halothane were performed by laser Doppler flowmetry. Variations of microcirculation in the compressed and uncompressed triceps ... [more ▼]

Measurements of muscular microcirculation in horses anaesthetised with halothane were performed by laser Doppler flowmetry. Variations of microcirculation in the compressed and uncompressed triceps brachii were measured when horses were positioned in dorsal recumbency after a prolonged period in lateral recumbency. A significant post ischaemic hyperaemia was recorded in horses which developed a post anaesthetic myositis. [less ▲]

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See detailEquine Postanaesthetic Myositis: A Possible Role for Free Radical Generation and Membrane Lipoperoxidation
Serteyn, Didier ULg; Mottart, E.; Deby-Dupont, G. et al

in Research in Veterinary Science (1990), 48(1), 42-6

A method for the evaluation of total plasma antihydroxyl and antiperferryl activity is described. This method was applied to horse plasma obtained during halothane anaesthesia. In horses suffering from ... [more ▼]

A method for the evaluation of total plasma antihydroxyl and antiperferryl activity is described. This method was applied to horse plasma obtained during halothane anaesthesia. In horses suffering from postanaesthetic myositis, a significant decrease in the antiperferryl activity was observed during anaesthesia particularly when the muscular compression produced by the weight of the horse was released. In the affected muscles, strong oxidants could therefore be generated during the reperfusion of the ischaemic muscles and might initiate membrane lipid peroxidation. This phenomenon could possibly explain the muscular damage observed in equine postanaesthetic myositis. [less ▲]

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See detailEquine postanaesthetic myositis: thromboxanes, prostacyclin and prostaglandin E2 production
Serteyn, Didier ULg; Deby, Ginette ULg; Pincemail, Joël ULg et al

in Veterinary Research Communications (1988), 12

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See detailEquine pulmonary and systemic haemodynamic responses to endothelin-1 and a selective ETA receptor antagonist
Benamou, A. E.; Marlin, D. J.; Lekeux, Pierre ULg

in Equine Veterinary Journal (2001), 33(4), 337-44

Based on previous in vitro studies, we hypothesised that endothelin (ET) would induce vasoconstriction in the pulmonary circululation of the horse and that this action would be mediated via ET(A ... [more ▼]

Based on previous in vitro studies, we hypothesised that endothelin (ET) would induce vasoconstriction in the pulmonary circululation of the horse and that this action would be mediated via ET(A) receptors. Pulmonary and systemic haemodynamic responses to endothelin-1 (ET-1), a potent vasoactive endogenous peptide, were investigated in 6 conscious, nonsedated horses at rest. Bolus i.v. injections of exogenous ET-1 (0.1, 0.2 and 0.4 microg/kg bwt) caused significant increases in pulmonary (PAP) and carotid (CAP) artery pressures, with peak increases of 79% and 51% for mean PAP and CAP, respectively. The effect of ET-1 on PAP and CAP was rapid and transient for PAP (-10 min) but prolonged for CAP (up to 60 min). ET-1 significantly decreased cardiac output by up to 35% and significantly increased systemic vascular resistance (SVR) by up to 104%. Pulmonary vascular resistance (PVR) showed a trend (P>0.05) to increase with 0.2 and 0.4 microg/kg bwt ET-1. Infusion of a selective ET(A) receptor antagonist (TBC11251) completely inhibited the responses to a subsequent bolus of 0.2 microg/kg bwt ET-1. We conclude that exogenous ET-1 exerts a potent vasoconstrictive action on the pulmonary and systemic circulations of the horse. These effects appear to be mediated largely through ET(A) receptors in both circulations. Endothelin may play a role in hypertensive conditions in the horse. [less ▲]

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See detailEquine respiratory diseases
Lekeux, Pierre ULg

Book published by International Veterinary Information Service - Last Updated 2008 (2008)

Detailed reference viewed: 137 (8 ULg)
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See detailEQUINE SEMEN FREEZING: STATE OF THE ART AND PERSPECTIVES.
Ponthier, Jérôme ULg

Conference (2011, November 19)

Depuis vingt ans, la congélation du sperme a permis de diffuser la génétique des étalons. Les congélations effectuées en dehors des saisons sportives permettent d’inséminer de nombreuses juments pendant ... [more ▼]

Depuis vingt ans, la congélation du sperme a permis de diffuser la génétique des étalons. Les congélations effectuées en dehors des saisons sportives permettent d’inséminer de nombreuses juments pendant que les étalons concourent dans des lieux éloignés. Les éleveurs ont en permanence accès à des doses d’insémination sans risques sanitaires. Cependant, malgré une bonne qualité de sperme frais, 20% des éjaculats équins ne supportent pas la congélation (Vidament, 2005). Le but de cette présentation est de revoir la physiologie du spermatozoïde et d’en discuter les implications dans le contexte de la congélation. Les améliorations des techniques de congélation présentes ou à venir seront aussi évoquées. [less ▲]

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See detailThe equine stifle and tarsus
Busoni, Valeria ULg; Audigié, Fabrice

in Textbook of Veterinary Diagnostic Radiology 6th Edition (2012)

This is a comprehensive chapter on radiology of the equine tarsus and stifle.

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See detailEquine Third Metacarpal Bone Assessment by Quantitative Ultrasound and Dual-Energy-X-Ray absorptiometry
Carstanjen, B; Duboeuf, F; Amory, Hélène ULg et al

in Proceedings of the 11th annual scientific meeting of the ECVS (2001)

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See detailEquine Third Metacarpal Bone Assessment by Quantitative Ultrasound and Dual-Energy-X-Ray absorptiometry.
Carstanjen, Bianca; Duboeuf, F.; Amory, Hélène ULg et al

in Veterinary Surgery : The Official Journal of the American College of Veterinary Surgeons (2001), 30

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See detailEQUINE THORACIC IMAGING: THE RATIONAL USE OF RADIOLOGY AND ULTRASONOGRAPHY
Busoni, Valeria ULg

in Proceedings du Congrès de l’Association de Vétérinaires Equins Francophones (AVEF) (2012)

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See detailEquine thoracic imaging: the rational use of radiology and ultrasonography
Busoni, Valeria ULg

in Hippos - Canifelis 2009 Proceedings (2009, January)

The abstract of this presentation describes the advantages and the disadvatages of radiology and ultrasonography in the assessment of the thoracic diseases of the horse. A list of diseases and situations ... [more ▼]

The abstract of this presentation describes the advantages and the disadvatages of radiology and ultrasonography in the assessment of the thoracic diseases of the horse. A list of diseases and situations in which each technique is most usefull alone or in combination of the other is given to the equine practicionner. [less ▲]

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See detailEquine trypsin: purification and development of a radio-immunoassay
Grulke, Sigrid ULg; Deby-Dupont, G.; Gangl, M. et al

in Veterinary Research (2003), 34(3, May-Jun), 317-330

Shock is accompanied by generalised splanchnic hypoperfusion, and splanchnic organs like the pancreas can be damaged, as shown in animal experimental models and in humans, by the presence of high plasma ... [more ▼]

Shock is accompanied by generalised splanchnic hypoperfusion, and splanchnic organs like the pancreas can be damaged, as shown in animal experimental models and in humans, by the presence of high plasma concentrations of trypsin and other pancreatic enzymes. In order to design a radioimmunoassay technique (RIA) for the measurement of equine trypsin-like immunoreactivity (TLI) in biological fluids, trypsin was purified (with purity greater than or equal to 96 %) from the equine pancreas by extraction in an acid medium, ammonium sulfate precipitations, gel filtration chromatography and, after activation of trypsinogen into trypsin, affinity chromatography. Gel polyacrylamide electrophoresis showed a monomeric enzyme with a molecular weight of 27 kDa. The purified equine trypsin served for the immunisation of rabbits in order to obtain a specific antiserum, and the labelled antigen was prepared by iodination of equine trypsin with I-125. The RIA was based on the binding of the antigen to the antibody followed by the separation of the antigen-antibody complex by immunoprecipitation in the presence of sheep anti-rabbit gammaglobulins and the assay of the radioactivity in the precipitate. The RIA showed good sensitivity, specificity, precision, accuracy and reproducibility. The reference mean value of TLI in the plasma of healthy horses (n = 20) was 30.01 +/- 6.84 ng/mL (upper confidence limit 50.52 ng/mL; p < 0.01). Three horses with non strangulating intestinal obstruction without shock showed TLI values within normal limits whereas 5 of 7 horses with strangulation obstruction showed TLI levels above the upper confidence limit. Further studies using the RIA and the enzymatic assay should be performed in order to confirm the role of the pancreas in equine intestinal obstruction. [less ▲]

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See detailEquiNox2: a new method to measure NADPH oxidase activity and to study effect of inhibitors and their interactions with the enzyme
Derochette, Sandrine ULg; Serteyn, Didier ULg; Mouithys-Mickalad, Ange ULg et al

in Talanta (2015)

Excessive neutrophil stimulation and reactive oxygen species (ROS) production are involved in numerous human or horse pathologies. The modulation of the neutrophil NADPH oxidase (NOX) has a great ... [more ▼]

Excessive neutrophil stimulation and reactive oxygen species (ROS) production are involved in numerous human or horse pathologies. The modulation of the neutrophil NADPH oxidase (NOX) has a great therapeutic potential since this enzyme produces superoxide anion whose most of the other ROS derive. The measurement of NOX activity by cell-free systems is often used to test potential inhibitors of the enzyme. A major drawback of this technique is the possible interferences between inhibitors and the probe, ferricytochrome c, used to measure the activity. We designed the "EquiNox2", a new pharmacological tool, to determine the direct interaction of potential inhibitors with equine phagocytic NOX and their effect on the enzyme activity or assembly. This method consists in binding the membrane fractions of neutrophils containing flavocytochrome b558 or the entire complex, reconstituted in vitro from membrane and cytosolic fractions of PMNs, onto the wells of a microplate followed by incubation with potential inhibitors or drugs. After incubation, the excess of the drug is simply eliminated or washed prior measuring the activity of the reconstituted complex. This latter step avoid the risk of interference between the inhibitor and the revelation solution and can distinguish if inhibitors, strongly bound or not, could interfere with the assembly of the enzymatic complex or with its activity. The EquiNox2 was validated using diphenyliodonium chloride and Gp91ds-tat, two well-known inhibitors largely described for human NADPH oxidase. The present technique was used to study and understand better the effect of curcumin and its water-soluble derivative, NDS27, on the assembly and activity of NOX. We demonstrated that curcumin and NDS27 can strongly bind to the enzyme and prevents its assembly making these molecules good candidates for the treatment of horse or human pathologies implying an excessive activation of neutrophils. [less ▲]

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See detailL'équipe de Mario Monti : un gouvernement de "techniciens" ? Médias et sens commun
Geuens, Geoffrey ULg

Article for general public (2011)

Detailed reference viewed: 46 (23 ULg)