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See detailEndodontie mécanisée
MAINJOT, Amélie ULg

Scientific conference (2004, October)

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See detailEndogenous Altruism, Redistribution, and Long Term Care
Pestieau, Pierre ULg; Cremer, Helmuth; Gahvari, Firouz

in B.E. Journal of Economic Analysis & Policy (2014), 14(2), 499-524

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See detailEndogenous and Exogenous Neuronal Rhythmicity
Drion, Guillaume ULg

Conference (2013, June 25)

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See detailEndogenous auxin and cytokinin levels in shoots of a nonrooting tobacco mutant
Faivre-Rampant, O.; Kevers, Claire ULg; Gaspar, Th

in Bulletin de la Societe Royale des Sciences de Liege (1999), 68(5-6), 318

[No abstract available]

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See detailEndogenous erythropoietin in the anemia of chronic disorders
Beguin, Yves ULg

in Weiss, W.; Gordeuk, V. R.; Hershko, C. (Eds.) Anemia of chronic disease (2005)

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See detailAn endogenous gibbon ape leukemia virus (GALV) identified in a rodent (Melomys sp.) from Indonesia
Alfano, niccolo; Michaux, Johan ULg; Fabre, Pierre-Henri et al

in Journal of Virology (2016)

Gibbon ape leukemia virus (GALV) and koala retrovirus (KoRV) most likely originated froma cross-species transmission of an ancestral retrovirus into koalas and gibbons via one or moreintermediate as yet ... [more ▼]

Gibbon ape leukemia virus (GALV) and koala retrovirus (KoRV) most likely originated froma cross-species transmission of an ancestral retrovirus into koalas and gibbons via one or moreintermediate as yet unknown hosts. A highly similar virus to GALV has been identified in anAustralian rodent (Melomys burtoni) after extensive screening of Australian wildlife. GALV-likeviruses have also been discovered in several Southeast Asian species although screening has not beenextensive and viruses discovered to date are only distantly related to GALV. We therefore screened 26Southeast Asian rodent species for KoRV- and GALV-like sequences, using hybridization capture andhigh-throughput sequencing, in the attempt to identify potential GALV and KoRV hosts. Only onespecies, an undescribed species of Melomys from Indonesia, was positive yielding an endogenousprovirus very closely related to a strain of GALV. The sequence of the critical receptor domain forGALV infection in the Indonesian Melomys sp. was consistent with the susceptibility of the species toGALV infection. The discovery of a GALV in a second Melomys species provides further evidencethat Melomys may play a role in the spread of GALV-like viruses, especially since the genus is foundin Indonesia, Papua New Guinea and Australia, connecting the home ranges of koalas and gibbons [less ▲]

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See detailAn endogenous gibbon ape leukemia virus (GALV) identified in a rodent (Melomys sp.) from Indonesia
Niccolo, Alfano; Michaux, Johan ULg; Fabre, pierre-Henri et al

in Journal of Virology (2016), sous presse

ABSTRACT Gibbon ape leukemia virus (GALV) and koala retrovirus (KoRV) most likely originated from a cross-species transmission of an ancestral retrovirus into koalas and gibbons via one or more ... [more ▼]

ABSTRACT Gibbon ape leukemia virus (GALV) and koala retrovirus (KoRV) most likely originated from a cross-species transmission of an ancestral retrovirus into koalas and gibbons via one or more intermediate as yet unknown hosts. A highly similar virus to GALV has been identified in an Australian rodent (Melomys burtoni) after extensive screening of Australian wildlife. GALV-like viruses have also been discovered in several Southeast Asian species although screening has not been extensive and viruses discovered to date are only distantly related to GALV. We therefore screened 26 Southeast Asian rodent species for KoRV- and GALV-like sequences, using hybridization capture and high-throughput sequencing, in the attempt to identify potential GALV and KoRV hosts. Only one species, an undescribed species of Melomys from Indonesia, was positive yielding an endogenous provirus very closely related to a strain of GALV. The sequence of the critical receptor domain for GALV infection in the Indonesian Melomys sp. was consistent with the susceptibility of the species to GALV infection. The discovery of a GALV in a second Melomys species provides further evidence that Melomys may play a role in the spread of GALV-like viruses, especially since the genus is found in Indonesia, Papua New Guinea and Australia, connecting the home ranges of koalas and gibbons. IMPORTANCE The gibbon ape leukemia virus (GALV) and the koala retrovirus (KoRV) are very closely related, yet their hosts are neither closely related nor overlap geographically. Direct cross-species infection between koalas and gibbons is unlikely. Therfore, GALV and KoRV may have arisen via a cross-species transfer from an intermediate host that overlaps in range with both gibbons and koalas. Using hybridization capture and high-throughput sequencing, we have screened a wide range of rodent candidate hosts from Southeast Asia for KoRV- and GALV-like sequences. Only a Melomys species from Indonesia was positive for GALV. We report the genome sequence of this newly identified GALV, the critical domain for infection of its potential cellular receptor and its phylogenetic relationships with the other previously characterized GALVs. We hypothesize that the genus Melomys may have played a key role in cross-species transmission to other taxa. [less ▲]

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See detailEndogenous Glutamate Involvement in Pulsatile Secretion of Gonadotropin-Releasing Hormone: Evidence from Effect of Glutamine and Developmental Changes
Bourguignon, Jean-Pierre ULg; Gerard, Arlette ULg; Alvarez Gonzalez, Maria-Luz ULg et al

in Endocrinology (1995), 136(3), 911-6

The secretion of GnRH can be stimulated by glutamate (GLU) and GLU agonists, whereas GLU receptor antagonists inhibit GnRH. Using 6-diazo-5-oxo-L-norleucine (DON), an inhibitor of glutaminase, we aimed to ... [more ▼]

The secretion of GnRH can be stimulated by glutamate (GLU) and GLU agonists, whereas GLU receptor antagonists inhibit GnRH. Using 6-diazo-5-oxo-L-norleucine (DON), an inhibitor of glutaminase, we aimed to study the involvement of endogenous GLU in GnRH secretion through the effects of impaired GLU biosynthesis from its precursor glutamine (GLN). GnRH secretion by hypothalamic explants of male rats, aged 15 and 50 days, was compared, because the frequency of spontaneous GnRH secretory pulses showed a 2-fold increase between those two ages. Using explants of 50-day-old rats, GLN elicited GnRH secretion in a similar dose-related manner as GLU. DON prevented GLN-evoked secretion of GnRH, whereas the effect of GLU was not altered. DON also markedly inhibited spontaneous pulsatile secretion of GnRH and the secretory response to veratridine, a Na+ channel opener. The inhibitory effect of DON on veratridine-evoked secretion of GnRH was directly related to the duration of exposure to DON and the frequency of GnRH secretory episodes. Using explants of 15-day-old rats, GLN could elicit GnRH release, although this response was lower than GLU-evoked secretion of GnRH. The DON concentrations required for inhibition of veratridine-evoked secretion of GnRH were lower at 15 days than at 50 days. These data indicate that 1) GLU biosynthesis from GLN is a prerequisite to the physiological mechanism of pulsatile GnRH secretion; and 2) inhibition of veratridine- or GLN-induced secretion of GnRH requires higher DON concentrations after the onset of puberty than before. This suggests that glutaminase, the enzyme controlling GLU biosynthesis from GLN, shows increased activity after the onset of puberty when the frequency of pulsatile GnRH secretion is increased as well. [less ▲]

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See detailEndogenous Growth and Regional Dynamics in an OLG Model with Land
Artige, Lionel ULg

Conference (2000, June)

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See detailEndogenous growth and regional dynamics in an OLG model with land
Artige, Lionel ULg

Conference (2001, November)

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See detailEndogenous Growth in an OLG Model with a Fixed Factor
Artige, Lionel ULg

E-print/Working paper (2010)

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See detailEndogenous mode of competition in general equilibrium
Tharakan, Joseph ULg

Conference (2005, November)

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See detailEndogenous mode of competition in general equilibrium
Tharakan, Joseph ULg

Conference (2009, March)

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See detailEndogenous mode of competition in general equilibrium
Tharakan, Joseph ULg

Conference (2006, November)

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See detailEndogenous mode of competition in general equilibrium
Tharakan, Joseph ULg

Conference (2007, May)

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See detailEndogenous mode of competition in general equilibrium
Tharakan, Joseph ULg

Conference (2011, October)

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See detailEndogenous mode of competition in general equilibrium
Tharakan, Joseph ULg

Conference (2010, December)

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See detailEndogenous murine leukemia retroviral variation across wild European and inbred strains of house mouse
Hartmann, Stephanie; Hasenkamp, Natasha; Mayer, Jens et al

in BMC Genomics (2015), DOI 10.1186/s12864-015-1766-z

Background: Endogenous Q1 murine leukemia retroviruses (MLVs) are high copy number proviral elements difficult to comprehensively characterize using standard low throughput sequencing approaches. However ... [more ▼]

Background: Endogenous Q1 murine leukemia retroviruses (MLVs) are high copy number proviral elements difficult to comprehensively characterize using standard low throughput sequencing approaches. However, high throughput approaches generate data that is challenging to process, interpret and present. 8 9 10 Results: Next generation sequencing (NGS) data was generated for MLVs from two wild caught Mus musculus domesticus (from mainland France and Corsica) and for inbred laboratory mouse strains C3H, LP/J and SJL. Sequence reads were grouped using a novel sequence clustering approach as applied to retroviral sequences. A Markov cluster algorithm was employed, and the sequence reads were queried for matches to specific xenotropic (Xmv), polytropic (Pmv) and modified polytropic (Mpmv) viral reference sequences. 11 12 13 14 15 Conclusions: Various MLV subtypes were more widespread than expected among the mice, which may be due to the higher coverage of NGS, or to the presence of similar sequence across many different proviral loci. The results did not correlate with variation in the major MLV receptor Xpr1, which can restrict exogenous MLVs, suggesting that endogenous MLV distribution may reflect gene flow more than past resistance to infection. [less ▲]

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See detailEndogenous nitric oxide modulates acetylcholine-induced edema and vasoconstriction in isolated perfused rabbit lungs.
Delaunois, Annie ULg; Gustin, Pascal ULg; Ansay, Michel ULg

in Journal of Pharmacology and Experimental Therapeutics (The) (1995), 274(2), 559-97

The modulatory role of endogenous nitric oxide (NO) on pulmonary edema induced by acetylcholine (ACh), capsaicin, substance P (SP) and 5-hydroxytryptamine (5-HT) was investigated by using an inhibitor of ... [more ▼]

The modulatory role of endogenous nitric oxide (NO) on pulmonary edema induced by acetylcholine (ACh), capsaicin, substance P (SP) and 5-hydroxytryptamine (5-HT) was investigated by using an inhibitor of NO synthase, N-omega-nitro-L-arginine (L-NNA). The effects of endogenous NO on the hemodynamic response to ACh, 5-HT and SP were also investigated. The capillary filtration coefficient (Kf,c), the total pressure gradient (delta Pt) and its four components [arterial (delta Pa), pre- (delta Pa') and post-capillary (delta Pv'), and venous gradient (delta Pv)] were evaluated on isolated, ventilated, perfused rabbit lungs. ACh (10(-8) to 10(-4) M) and SP (10(-10) to 10(-6) M) induced a concentration-dependent increase in the Kf,c. Capsaicin (10(-4) M) and 5-HT (10(-4) M) also increased this parameter. L-NNA (10(-4) M) completely inhibited the effects of ACh and capsaicin on the Kf,c, without preventing the effects of SP and 5-HT. ACh induced a concentration-dependent vasoconstriction in the precapillary segment. Pretreatment with L-NNA enhanced this increase in delta Pa' but also increased delta Pv' and delta Pv. 5-HT increased delta Pt and delta Pa proportionally to the concentration. This effect was enhanced by L-NNA, which also increased delta Pa'. SP had no significant hemodynamic effect. Pretreatment with L-NNA did not modify the response to SP. Sodium nitroprusside (10(-5) M) induced a left shift of the concentration-response curve to ACh on the Kf,c, although it did not change the response to SP. Sodium nitroprusside also inhibited the hemodynamic effect of ACh. It was concluded that endogenous NO is involved in ACh-and capsaicin-induced edema via a prejunctional stimulatory effect on the C-fibers. Endogenous NO can also modulate ACh- and 5-HT-induced vasoconstriction by exerting a vasodilator action on the whole pulmonary vascular bed. [less ▲]

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