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See detailFamilial pituitary adenomas : current concepts and perspectives
jaffrain-Rea, ML; Beckers, Albert ULg

in Abstract book - National Symposium in Endocrinology - Romanian Society of Endocrinology (2012, April)

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See detailFamilial Pituitary Adenomas : genotype and phenotype
Beckers, Albert ULg

in Growth Hormone related diseases and therapy : a molecular and physiological perspective for the Clinician (2009)

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See detailFamilial pituitary adenomas.
Tichomirowa, M. A.; Daly, Adrian ULg; Beckers, Albert ULg

in Journal of Internal Medicine (2009), 266(1), 5-18

The majority of pituitary adenomas occur sporadically, however, about 5% of all cases occur in a familial setting, of which over half are due to multiple endocrine neoplasia type 1 (MEN-1) and Carney's ... [more ▼]

The majority of pituitary adenomas occur sporadically, however, about 5% of all cases occur in a familial setting, of which over half are due to multiple endocrine neoplasia type 1 (MEN-1) and Carney's complex (CNC). Since the late 1990s we have described non-MEN1/CNC familial pituitary tumours that include all tumour phenotypes, a condition named familial isolated pituitary adenomas (FIPA). The clinical characteristics of FIPA vary from those of sporadic pituitary adenomas, as patients with FIPA have a younger age at diagnosis and larger tumours. About 15% of FIPA patients have mutations in the aryl hydrocarbon receptor interacting protein gene (AIP), which indicates that FIPA may have a diverse genetic pathophysiology. This review describes the clinical features of familial pituitary adenomas like MEN1, the MEN 1-like syndrome MEN-4, CNC, FIPA, the tumour pathologies found in this setting and the genetic/molecular data that have been recently reported. [less ▲]

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See detailFamilial Pituitary Syndromes
Beckers, Albert ULg

Scientific conference (2012, October)

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See detailFamilial Pituitary Syndromes
Beckers, Albert ULg

in 12th ESE PostGraduate Course in Clinical Endocrinology - Abstract book (2012, October)

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See detailFamilial pituitary tumor syndromes
Beckers, Albert ULg

Scientific conference (2010, September 16)

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See detailA familial pituitary tumor syndromes
Vasilev, Vladimir; Daly, Adrian ULg; PETROSSIANS, Patrick ULg et al

in Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists (2011), 17(3),

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See detailFamilial Pituitary Tumors
Beckers, Albert ULg

in Meet the Professor Handouts : ENDO 2005 - The Endocrine Society's, 87th annual meeting (2005)

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See detailFamilial Pituitary Tumors
Beckers, Albert ULg

Scientific conference (2003, September)

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See detailFamilial Pituitary Tumors
Beckers, Albert ULg

Scientific conference (2001, March)

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See detailFamilial Pituitary Tumors
Beckers, Albert ULg

Scientific conference (2005, June)

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See detailFamilial Pituitary tumors
Valdes Socin, Hernan Gonzalo ULg; Poncin, J.; Vanbellinghen, Jean-François ULg et al

in Neuroendocrinologica : Dalla Riserca di base alla Clinica (2002)

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See detailFamilial pituitary tumors involving the Aryl Hydrocarbon Receptor Interacting Protein (AIP1)
Beckers, Albert ULg

in 11th International Workshop on Multiple Endocrine Neoplasia - Symposium 1 "Multiple Tumors and tje pituitary" - Abstract book (2008)

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See detailFamilial Pituitary tumours involving the Aryl Hydrocarbon Receptor Interacting Protein (AIP1)
Beckers, Albert ULg

Scientific conference (2008, September)

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See detailFamilial secreting-pinealomas : biological and preliminary genetic studies
Allouch, A.; Valdes Socin, Hernan Gonzalo ULg; Hendrick, J. C. et al

in 10th Meeting of the European Neuroendocrine Association - Abstract book (2002)

Introduction: Sporadic pinealomas are intracranial tumors which incidence account for less than 1/107. This is the second report of secretory familial pinealoma in a mother and sister. We report for the ... [more ▼]

Introduction: Sporadic pinealomas are intracranial tumors which incidence account for less than 1/107. This is the second report of secretory familial pinealoma in a mother and sister. We report for the first time neuroendocrine and preliminary genetic studies in these benign tumors. Methods and patients: Radioimmunoassay of urinary 6-sulphatoxymelatonin (a-MT6s) was performed in patients and in 90 control subjects aged 19-67 years. Samples were collected at 19-23 , 23-07 and 07-11 h. Endocrine studies including PRL, TSH, LH, FSH, ACTH, IGF1 and tumoral markers (bHCG, NSE, CEA) levels were measured. Lymphocytes caryotype was determined by CGH. Pituitary and pineal MRI were done in both patients. Results: The daughter was the index case. Diagnosis was done because of headaches. Pineal MRI showed a 17 x 14x 25 mm cystic lesion with gadolinium enhancement and no ventricular dilatation. Circadian rhythm of urinary a-MT6s was present but a-MT6s levels were clearly elevated compared to age-matched controls: 1455 ng/h at 19-23hs (308  261), 6012 ng/h at 23-07hs (1423753) and 3280 ng/h at 07-11hs (579340). The 55 years-old mother reported similar complaints during the daughter's follow-up. A pineal MRI identified a 18 x 20 x 14 mm cystic lesion. There were no signs of intracranial hypertension. None of the women reported sleep disturbances. Circadian rhythm of urinary a-MT6s was lost but a-MT6S levels were clearly elevated : 2380 ng/h at 19-23hs (173  153), 2812 ng/h at 23-07hs (768486) and 1897 ng/h at 07-11hs (480383). Endocrine studies and tumoral markers were in the normal range. No chromosomal abnormalities were found in both women (46,XX). Discussion: Due to the rare occurrence of sporadic pinealomas it is unlikely that such a tumor afflict two members in the same family. Although no histological proof was obtained in our patients, radiological findings and tumoral hypersecretion of melatonin derivated a-MT6s clearly suggest the pineal origin of these tumors. We suggest an autosomal dominant form of transmission with incomplete dominance as the most probable model of inheritance of familial pinealoma. [less ▲]

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See detailFamilial trends of obesity through three generations: the Belgian-Luxembourg child study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in International Journal of Obesity (1995), 19 Suppl 3

Province de Luxembourg in Belgium is an area with clustering of obesity as well as other risk factors for cardiovascular diseases and non-insulin dependent diabetes mellitus. In this study, obesity was ... [more ▼]

Province de Luxembourg in Belgium is an area with clustering of obesity as well as other risk factors for cardiovascular diseases and non-insulin dependent diabetes mellitus. In this study, obesity was studied in a total of 1028 boys and girls in age-strata 6-8, 8-10, 10-12 years, selected at random from school classes. Participation rate was about 70%. Non-participants did not differ from participants in comparisons of school records of height and weight. Furthermore, information on birth weight, parents' height and weight was collected, as well as reported problems of obesity in grandparents. The results show a high prevalence of pronounced obesity in these children. BMIs were strongly correlated between the children and both parents. Furthermore, grandparents' obesity problems were related to the BMI of parents, and also to obesity indices in the children. Birth weights were related to current BMI of the children (in girls only for the youngest age-group), and to their mothers' BMI. It was concluded that obesity is prevalent in this area and can be traced through three generations, and seems to be discoverable already at birth. Energy intake is high and physical activity level is low in these children. However, statistical analyses suggest that familial factors exert a greater impact than environmental factors on the BMI of the children. These results, as well as the wide-spread, consistent familial clustering of obesity, traceable already at birth, suggest influence of strong genetic traits for obesity in this population. [less ▲]

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See detailFamiliar person recognition: do we remember more episodic memories from faces than from names?
Barsics, Catherine ULg; Brédart, Serge ULg

Poster (2009)

This study was aimed at investigating whether the recognition of familiar faces is more likely to be associated with an experience of Remembering than the recognition of familiar names. Using the Remember ... [more ▼]

This study was aimed at investigating whether the recognition of familiar faces is more likely to be associated with an experience of Remembering than the recognition of familiar names. Using the Remember/Know paradigm the proportions of episodic memories recalled following the recognition of famous faces and names (Conditions) were assessed. Presented faces and names were previously judged by an independent group of participants as eliciting an equivalent level of familiarity. Nevertheless significant differences between the two conditions appeared in hit and false alarm rates. However, present results showed no significant difference in the recollection of personal memories (Remember responses conditionalized on the hits), following familiar faces compared with familiar names recognition. This finding contrasts with recent accounts assuming that faces are more prone to yield episodic memories than other cues to person identity. These results and their implications for current Interactive Activation and Competition person recognition models are discussed. [less ▲]

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See detailFamiliar person recognition: Is autonoetic consciousness more likely to accompany face recognition than voice recognition?
Barsics, Catherine ULg; Brédart, Serge ULg

in Dubois, Daniel (Ed.) COMPUTING ANTICIPATORY SYSTEMS, CASYS'09 - Ninth International Conference, Liège, Belgium, 3-8 August 2009 (2009, August 05)

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See detailFamiliarité spatiale dans deux communes périurbaines belges
Dubois, Charline ULg; Schmitz, Serge ULg

in Cahiers de Géographie du Quebec (2011), 55(154), 51-65

Analysing spatial familiarity aims to measure how places included in the life-world and in the cognitive map are familiar. Based on the study of Gale, Golledge, Halperin & Couclelis (1990), this paper ... [more ▼]

Analysing spatial familiarity aims to measure how places included in the life-world and in the cognitive map are familiar. Based on the study of Gale, Golledge, Halperin & Couclelis (1990), this paper explores the spatial familiarity of the inhabitants of two municipalities at the fringe of Liege (Belgium): it questions the links between the cognitive dimensions (visual, nominal, localisation) and themselves and the behavioural dimension (passing). It seeks new relevant places for the population of these urban fringe as well as the favourable factors to a good familiarity of a place. Finally, it scrutinizes the influence of people's mobility – period of residence, commuting to work, modes of transport – on spatial familiarity. [less ▲]

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