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See detailEthanol neurotoxicity: from basic science to clinical reality
De Witte, Philippe; Ward, Roberta; Dahchour, Abdelkhader et al

in Alcohol & Alcoholism (1999), 34

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See detailEthanol-conditioned withdrawal syndrome
Quertemont, Etienne ULg; De Witte, Philippe

in Proceedings of the 22nd European Winterconference on Brain Research (2002)

The withdrawal syndrome is closely related to the concepts of tolerance and physical dependence. The chronic consumption of a drug is believed to induce adaptive changes that are designed to oppose the ... [more ▼]

The withdrawal syndrome is closely related to the concepts of tolerance and physical dependence. The chronic consumption of a drug is believed to induce adaptive changes that are designed to oppose the acute effects of the drug. Such adaptive changes increase the tolerance to acute drug effects but lead to physical dependence, which is revealed by withdrawal symptoms when the drug is cleared from the body. However, another form of adaptive response to repeated drug consumption has been identified. This adaptive response appears after the intermittent repeated administration of a drug in association with the same set of environmental stimuli. After several associations, these environmental stimuli become able to induce a conditioned adaptive response. Such response leads to the phenomenon of “environment-dependent tolerance” that was observed with many drugs of abuse. However, if the drug is not administered, the conditioned stimuli alone may induce a “conditioned withdrawal syndrome”. Although less studied than the classical withdrawal syndrome, this conditioned withdrawal syndrome may be of importance for the development of drug dependence. In our experiments, we have studied the development of a conditioned withdrawal syndrome after repeated associations of a specific set of environmental stimuli with ethanol injections in Wistar rats. After repeated administrations of ethanol, the rats showed a clear environmental-dependent tolerance to ethanol. Furthermore, these conditioned stimuli induced behavioral (hyperexcitation) and neurochemical (increase glutamate release) responses similar to those observed after chronic alcohol withdrawal. [less ▲]

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See detailEthanol-induced behaviors in mice genetically deficient in MCH1 receptors
Didone, Vincent ULg; Tirelli, Ezio ULg; Quertemont, Etienne ULg et al

in Alcoholism, Clinical & Experimental Research (2010), 34(8), 93-93

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See detailEthanol-induced brain extracellular taurine release: an osmoregulatory mechanism?
Quertemont, Etienne ULg; Devitgh, Audrey; De witte, Philippe

in Alcohol & Alcoholism (2001), 36

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See detailEthanol-induced taurine release in rats genetically selected for ethanol preference and sensitivity
Quertemont, Etienne ULg; Colombo, Giancarlo; De Witte, Philippe

in Alcohol & Alcoholism (2001), 36

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See detailEthanolic fermentation as a tool for high added value products purification from biomass
Destain, Jacqueline ULg; Laurent, Pascal ULg; Thonart, Philippe ULg et al

Poster (2008)

The biorefinery concept implies the development of processes in order to valorise the whole part of a crop. In this concept, white biotechnologies are usually considered for the production of new ... [more ▼]

The biorefinery concept implies the development of processes in order to valorise the whole part of a crop. In this concept, white biotechnologies are usually considered for the production of new compounds or compounds actually derived from the oil industry. For example, interest in ethanolic fermentation is growing nowadays, mainly for its energetic applications, starting from starch or saccharose. Biorefinery integrating lignocellulosic materials are under development. Whatever the initial substrate may be, wet technologies would produce sugars and other soluble materials from the biomass. Different results could be expected:most of the hydrolysates molecules are used by the microorganisms;some molecules could be inhibitors for the fermentation;some molecules are "indifferent ones" and could be concentrated by the fermentation proccess followed by distillation. In the latest case, these molecules are concentrated in the residual medium and could be more easily recuperated. An example of this exists in the production of ethanol from beet. The different juices (diffusion, clarified, ...) contain molecules such as raffinose, glutamine, betaine, saponins or pectic materials. Some products are used by the yeasts and other are concentrated. Our purpose is to summary the results obtained, allowing the development of the concept in other biorefinery applications. [less ▲]

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See detailAn Ethclass in Belgium
Jamin, Jérôme ULg

in Towards an emerging ethclass in Europe (1999)

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See detailEther suicide poisoning by intravenous injection
LAMBERMONT, Bernard ULg; D'Orio, Vincenzo ULg

in Intensive Care Medicine (1999), 25(3), 338

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See detailEthical implications : pain, coma and related disorders
Schnakers, Caroline ULg; Faymonville, Marie ULg; Laureys, Steven ULg

in Banks, William P. (Ed.) Encyclopedia of Consciousness (2009)

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See detailEthical questions pertaining to the use of placebos
Mormont, Christian ULg

in Weisstub, D. N. (Ed.) Research on human subjects (1998)

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See detailEthics at the University
Robert, Jocelyne ULg

Scientific conference (2013, November 21)

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See detailEthics at the University: the sky is the limit
Robert, Jocelyne ULg

Scientific conference (2013, November 21)

Detailed reference viewed: 35 (8 ULg)
See detailEthics for Energy Technologies
Kopriwa, Nicole; Pfennig, Andreas ULg

Poster (2008)

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See detailThe ethics in disorders of consciousness
Demertzi, Athina ULg; LAUREYS, Steven ULg; Bruno, Marie-Aurélie ULg

in Vincent, J. L. (Ed.) Annual Update in Intensive Care and Emergency Medicine (2011)

The introduction of the mechanical ventilator in the 1950s and the development of intensive care in the 1960s permitted many patients to sustain their vegetative functions and survive severe injuries ... [more ▼]

The introduction of the mechanical ventilator in the 1950s and the development of intensive care in the 1960s permitted many patients to sustain their vegetative functions and survive severe injuries. Despite such advances, in many cases patients were found to suffer from altered states of consciousness which had never been encountered before as these patients would normally have died from apnea [1]. The imminent ethical impact of these profound states of unconsciousness was reflected in the composition of the first bioethical committees discussing the redefinition of life and the concept of therapeutic obstinacy. In 1968, the Ad Hoc Committee of Harvard Medical School published a milestone paper for the redefinition of death as irreversible coma and brain failure [2]. The committee was comprised of ten physicians, a theologian, a lawyer and a historian of science, betokening the medical, legal and societal debates that were to follow. We will here give a brief overview of some ethical issues related to the concept of consciousness and the medical management of patients with disorders of consciousness, such as comatose, vegetative and minimally conscious states that may be encountered in the intensive care setting. We will emphasize the problem of pain management and end-of life decision-making. [less ▲]

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See detailEthics of knowledge in General Practice Family Meddicine
Jamoulle, Marc ULg

Conference (2015, March 20)

some thoughts about ethics and knowledge in health care

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See detailThe ethics of managing disorders of consciousness
Demertzi, Athina ULg; Gosseries, Olivia ULg; Bruno, Marie-Aurélie ULg et al

in Schnakers, Caroline; Laureys, Steven (Eds.) Coma and disorders of consciousness (2012)

Detailed reference viewed: 38 (3 ULg)
See detailEthik materieller Lebensgrundlagen
Fayyaz, Sara; Hillerbrand, Rafaela; Pfennig, Andreas ULg

Conference (2009)

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See detailEthik materieller Lebensgrundlagen
Hillerbrand, Rafaela H; Pfennig, Andreas ULg

in Chemie Ingenieur Technik (2009), 81(8), 1219-1220

Detailed reference viewed: 11 (0 ULg)