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See detailEffects of 3 months of controlled whole body vibrations with low exposure period on the risk of falls among nursing home residents
Beaudart, Charlotte ULiege; Maquet, Didier ULiege; Mannarino, Mélanie et al

in Proceeding of the meeting (2013, February 22)

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See detailEffects of 3 months of short sessions of controlled whole body vibrations on the risk of falls among nursing home residents
Beaudart, Charlotte ULiege; Maquet, Didier ULiege; Mannarino, Mélanie et al

in BMC Geriatrics (2013), 13(42),

Background: Fatigue, lack of motivation and low compliance can be observed in nursing home residents during the practice of physical activity. Because exercises should not be too vigorous, whole body ... [more ▼]

Background: Fatigue, lack of motivation and low compliance can be observed in nursing home residents during the practice of physical activity. Because exercises should not be too vigorous, whole body vibration could potentially be an effective alternative. The objective of this randomized controlled trial was to assess the impact of 3-month training by whole body vibration on the risk of falls among nursing home residents. Methods: Patients were randomized into two groups: the whole body vibration group which received 3 training sessions every week composed of 5 series of only 15 seconds of vibrations at 30 Hz frequency and a control group with normal daily life for the whole study period. The impact of this training on the risk of falls was assessed blindly by three tests: the Tinetti Test, the Timed Up and Go test and a quantitative evaluation of a 10-second walk performed with a tri-axial accelerometer. Results: 62 subjects (47 women and 15 men; mean age 83.2 ± 7.99 years) were recruited for the study. No significant change in the studied parameters was observed between the treated (n=31) and the control group (n=31) after 3 months of training by controlled whole-body-vibrations. Actually, the Tinetti test increased of + 0.93 ± 3.14 points in the treated group against + 0.88 ± 2.33 points in the control group (p = 0.89 when adjusted). The Timed Up and Go test showed a median evolution of - 1.14 (− 4.75-3.73) seconds in the treated group against + 0.41 (− 3.57- 2.41) seconds in the control group (p = 0.06). For the quantitative evaluation of the walk, no significant change was observed between the treated and the control group in single task as well as in dual task conditions. Conclusions: The whole body vibration training performed with the exposition settings such as those used in this research was feasible but seems to have no impact on the risk of falls among nursing home residents. Further investigations, in which, for example, the exposure parameters would be changed, seem necessary [less ▲]

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See detailEffects of 3-alkylamino-7-chloro-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides on smooth muscle contractile activity
Ouedraogo, R.; Fontaine, J.; Antoine, M.-H. et al

in Pharmacy and Pharmacology Communications (2000), 6

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See detailEffects of 4-Hydroxy-2-Nonenal, a Major Lipid Peroxidation-Derived Aldehyde, and N-Acetylcysteine on the Cyclooxygenase-2 Expression in Human Uterine Myometrium.
Temma-Asano, K.; Tskitishvili, Ekaterine ULiege; Kanagawa, T. et al

in Gynecologic & Obstetric Investigation (2011)

Background: Chorioamnionitis is one of the important causes of preterm labor. Preterm labor with chorioamnionitis is associated with oxidative stress. We reported that 4-hydroxy-2-nonenal (4-HNE), a major ... [more ▼]

Background: Chorioamnionitis is one of the important causes of preterm labor. Preterm labor with chorioamnionitis is associated with oxidative stress. We reported that 4-hydroxy-2-nonenal (4-HNE), a major end product of oxidative fatty acid metabolism, is accumulated in the placenta with chorioamnionitis. The aim of this study was to confirm the effect of 4-HNE on cyclooxygenase-2 (COX-2) and prostaglandin (PG) induction in the uterine myometrial tissues. We also examined the effect of N-acetylcysteine (NAC) on 4-HNE-induced COX-2 expression. Methods: Uterine myometrial tissues were obtained from 5 patients. One of them underwent elective cesarean section without labor, and 4 of them underwent hysterectomy because of placental previa or atonic bleeding. We stimulated the uterine myometrial tissues with 4-HNE. In addition, the tissues were pretreated with NAC before 4-HNE treatment. The expression of COX-2 mRNA was observed by real-time PCR. PGE2 and prostacyclin release into the supernatants of the tissue cultures was measured by ELISA. Results: 4-HNE induced the COX-2 mRNA expression and PGE2 production in the uterine myometrial tissue culture in a dose-dependent and time-dependent manner. NAC inhibited 4-HNE-induced COX-2 expression. Conclusion: 4-HNE may play an important role in preterm labor. NAC might be protective against preterm labor under oxidative stress. [less ▲]

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See detailEffects of 6-substituted 2-oxo-2H-1-benzopyran-3-carbowylic acide derivatives on cellular invasion in vitro
Kempen, I.; Frankenne, F.; Noël, Agnès ULiege et al

Poster (2002, November 15)

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See detailEffects of 8-epi-Pgf2alpha on isolated bronchial smooth muscle of healthy and heaves-affected horses
Kirschvink, Nathalie; Art, Tatiana ULiege; Lekeux, Pierre ULiege et al

in Journal of Veterinary Pharmacology & Therapeutics (2001), 24(3), 215-221

8-Epi-PGF2alpha, a prostaglandin-like compound generated by oxidative stress, has been shown to be an in vitro bronchoconstrictor in airways from healthy laboratory animals and healthy humans, but it has ... [more ▼]

8-Epi-PGF2alpha, a prostaglandin-like compound generated by oxidative stress, has been shown to be an in vitro bronchoconstrictor in airways from healthy laboratory animals and healthy humans, but it has never been studied in diseased airways. Here, the bronchoconstrictive capacity of 8-epi-PGF2alpha on isolated bronchial rings (BR) of healthy and heaves-affected horses was evaluated by comparing the maximal effect and the potency of 8-epi-PGF2alpha to those of (1) acetylcholine (ACh), (2) its stereoisomer PGF2alpha and (3) its synthetic receptor agonist, U46619. Furthermore, the potential capacity of 8-epi-PGF2alpha to enhance the cholinergic (ACh) responsiveness of bronchial smooth muscle was investigated. 8-Epi-PGF2alpha contracted BR with a rank order of efficacy of Ach > U44619 > PGF2alpha > 8-epi-PGF2alpha in both healthy and heaves-affected horses. The contractile maximal response elicited by 8-epi-PGF2alpha was significantly smaller than that elicited by the other drugs, but was significantly higher in BR from heaves-affected horses than in those sampled in healthy horses, whilst pD2 values were similar. A subthreshold concentration of 8-epi-PGF2alpha (10-7 M) did not induce in vitro cholinergic hyper-responsiveness in BR of either healthy or heaves-affected horses. In conclusion, it has been demonstrated that 8-epi-PGF2alpha is an in vitro bronchoconstrictor of minor importance in healthy horses, but whose efficacy is significantly increased in heaves-affected horses. [less ▲]

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See detailEffects of a 1-year treatment with a low-dose combined oral contraceptive containing ethinyl estradiol and cyproterone acetate on glucose and insulin metabolism.
Scheen, André ULiege; Jandrain, Bernard ULiege; Humblet, Dominique ULiege et al

in Fertility and Sterility (1993), 59(4), 797-802

OBJECTIVE: To study the effects of the slightly estrogen-dominant monophasic low-dose oral contraceptive (OC) Diane-35 (Schering AG, Berlin, Germany) (35 micrograms ethinyl estradiol [EE2] + 2 mg ... [more ▼]

OBJECTIVE: To study the effects of the slightly estrogen-dominant monophasic low-dose oral contraceptive (OC) Diane-35 (Schering AG, Berlin, Germany) (35 micrograms ethinyl estradiol [EE2] + 2 mg cyproterone acetate, a 17 alpha-hydroxyprogesterone derivative [17-OHP]) on glucose and insulin metabolism. DESIGN: Seven healthy young women were investigated by using the euglycemic hyperinsulinemic glucose clamp technique (insulin delivery rate = 100 mU/kg per hour for 120 minutes). This test was performed, after an overnight fast, during the last 7 days of a spontaneous cycle and within the last 5 days of pill intake during the sixth and twelfth cycle of a continuous treatment with Diane-35 in each subject. RESULTS: The three indexes measuring the insulin-induced glucose disposal during the clamp (glucose infusion rate, glucose metabolic clearance rate, and glucose infusion rate divided by plasma insulin plateau levels) were not significantly affected by Diane-35. In contrast, the metabolic clearance rate of the exogenous insulin infused during the clamp tended to be slightly increased with Diane-35 (significant after 6 but not after 12 cycles). CONCLUSION: These results suggest that a 1-year treatment with the OC Diane-35, which contains EE2 + a 17-OHP rather than a 19-nortestosterone derivative as the progestogen compound, does not significantly alter peripheral (presumably muscular) insulin sensitivity but slightly increases insulin (presumably hepatic) clearance. [less ▲]

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See detailThe effects of a cadmium exposure on poplar plants: A combined proteomic, physiological and biochemical approach to unravel stress-responses in poplar.
Kieffer, Pol ULiege

Doctoral thesis (2012)

The industrial revolution in the 1800s and the subsequent industrialization had the consequence of an anthropogenic release of many organic and inorganic pollutants. Among these pollutants, cadmium is ... [more ▼]

The industrial revolution in the 1800s and the subsequent industrialization had the consequence of an anthropogenic release of many organic and inorganic pollutants. Among these pollutants, cadmium is very problematic due to its high toxicity. It can induce significant damage to the vegetation and an accumulation in farmland introduces the pollutant into the food chain. This creates a possible major health risk for humans. Poplar plants, as a member of the Salicaceae family, seem to possess a certain tolerance to this toxic metal and accumulate significant amount in their aerial parts, making poplar a possible candidate for phytoremedation. The metabolic and physiological impact of cadmium have been studied as well in field trials as in controlled laboratory conditions, but mostly in clearly targeted studies focusing on a few key aspects. The recent advent of more global techniques such as transcriptomics and proteomics, make it possible to obtain new results. In the thesis presented here, a proteomic study of the short-term and long-term effects of cadmium on poplar leaf and roots metabolic processes in controlled laboratory conditions was carried out. With the help of this technique, complemented with biochemical and physiological approaches and with morphological observations, it was possible to obtain results on the stress-coping mechanisms underlying an acute first response, but also on the more general adaptation mechanism which make it possible for the poplar plants to tolerate significant amounts of cadmium. Results showed a negative impact on important cell processes like photosynthesis and ATP synthesis and the antioxidant system, explaining the impaired growth. Similar results could be obtained in roots, although the stress seemed much more acute, as evidenced by the stronger accumulation of typical stress proteins (i.e. heat shock proteins). In a final set of experiments a controlled combination of two stresses (cadmium and nonlethal chilling stress; 4°C) allowed separating specific cadmium responses from a more general stress response. Cadmium had a much more severe impact on plant survival when combined with an additional constraints. In this present work, the procedures, results and conclusions obtained are presented in detail. [less ▲]

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See detailEffects of a commercial formulation of a plant resistance elicitor on non-target organisms
Jansen, Jean-Pierre; Buenotesta, Raphaël; Schiffers, Bruno ULiege

in Bulletin OILB/SROP = IOBC/WPRS Bulletin (2014), 103

The toxicity of Fyto11, a plant resistance elicitor commercial formulation used to increase the natural resistance of Cucurbitaceae (cucumber, zucchini and melon) and Solanaceae (tomato and sweet pepper ... [more ▼]

The toxicity of Fyto11, a plant resistance elicitor commercial formulation used to increase the natural resistance of Cucurbitaceae (cucumber, zucchini and melon) and Solanaceae (tomato and sweet pepper) against powdery mildew under greenhouse conditions, has been assessed on several beneficial arthropods: the honeybee Apis mellifera, the predatory miteTyphlodromus pyri, the aphid parasitic wasp Aphidius rhopalosiphi and the aphid predator Episyrphus balteatus. Tested at 0.5% and 1.0% spray dilution on plants, Fyto11 did not lead to significant corrected mortalities for E. balteatus larvae and adult wasps of A. rhopalosiphi, with a maximum of 5.4% mortality. No effects on reproduction capacity of the parasitic wasps were observed. The exposure of T. pyri protonymphs to Fyto11 on glass plates lead to corrected mortalities of 1.1% and 32.6% at 0.5% and 1.0% and to a reduction of female fertility of 9.0% and 25.4%, compared to the control performance. When assessed on the honeybee by contact and oral exposure, Fyto11 did not lead to significant effects, with LD50 estimated as > 10 μg a.i./bee (oral) and 12.5 μg a.i./bee (contact), leading to HQ ratio < 50 and classifying the product at no or low risk for honeybees. These results showed that the product was harmless for all beneficials at the proposed commercial rate, except for T. pyri at 1.0% on glass plates, where the product was rated as slightly harmful. Even if all the beneficial species’ diversity has not been assessed with this product, negative effects on non-target organisms are not expected in field conditions and Fyto11 can be considered as compatible with IPM programs. [less ▲]

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See detailEffects of a daily physical education programme on the attitude of elementary school pupils
Piéron, Maurice ULiege; Delfosse, Catherine; Cloes, Marc ULiege

in University of Victoria (Ed.) Proceedings of the 10th Commonwealth & International Scientific Congress. Access to Active Living (1994)

A daily physical educationprogramme (one 40 minute session) lasting for three years was implemented in 14 schools (kindergarten and primary levels). These schools were located in the whole territory of ... [more ▼]

A daily physical educationprogramme (one 40 minute session) lasting for three years was implemented in 14 schools (kindergarten and primary levels). These schools were located in the whole territory of the French Community in Belgium. More than 3.500 children were involved in the experimental programme. Its implementation demanded a close cooperation between classroom teachers and physical education specialists. The evaluation of the effects of the daily physical education programme was copleted on the basis of a multidimensional data collection. This paper deals essentially with the children's attitudes in the comparison of experimental aned control schools and the longitudinal aspect of the study. A progressive deterioration of the pupils' attitude towards school was evidenced. However, children from the experimental classes maintained a significantly more favourable attitude towareds school and towards classroom and specialists teachers than pupils from control classes at each investigated level. [less ▲]

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See detailEffects of a dietary vitamin E supplementation on performance and meat characteristics in fattening bulls from the Belgian Blue breed
Dufrasne, Isabelle ULiege; Marche, Christian; Clinquart, Antoine ULiege et al

in Livestock Production Science (1998), 65(1/2), 197-201

An experiment was conducted to study effects of dietary vitamin E supplementation on animal performance, slaughter characteristics and meat quality traits in Belgian Blue double-muscled bulls. Two groups ... [more ▼]

An experiment was conducted to study effects of dietary vitamin E supplementation on animal performance, slaughter characteristics and meat quality traits in Belgian Blue double-muscled bulls. Two groups of six bulls each (404 kg) were offered (close to ad libitum) a fattening diet based on sugar beet pulp for 154 days, at which time they were slaughtered. The diet given to the control group (CG) contained 12.5 mg vitamin E/kg concentrate. The vitamin E-treated group (VG) received the same concentrate plus a supplement of 1000 mg vitamin E per bull daily. Steaks from m. longissimus thoracis were used to determine meat quality characteristics, α tocopherol concentration and thiobarbituric acid reactive substances content (TBARS), an indicator of oxidation rancidity. Supplementation had no influence on performance or carcass characteristics. The main findings were that vitamin E doubled the muscle alpha tocopherol level (1.9 vs. 0.9 mg/kg; P<0.001), lipid oxidation was suppressed as indicated by TBARS values (P<0.01 at days 7, 9, 11 and 14 after slaughter), but muscle colour was not significantly affected although a* (redness) tended to be higher for VG. [less ▲]

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See detailThe effects of a documentary film about schizophrenia on cognitive, affective and behavioural aspects of stigmatisation
Thonon, Bénédicte ULiege; Pletinx, Amandine; Grandjean, Allison et al

in Journal of Behavior Therapy and Experimental Psychiatry (2016), 50

Background and Objectives: Stereotypes about schizophrenia may lead to prejudicial attitudes and discrimination with debilitating effects on people diagnosed with schizophrenia. There is thus a need to ... [more ▼]

Background and Objectives: Stereotypes about schizophrenia may lead to prejudicial attitudes and discrimination with debilitating effects on people diagnosed with schizophrenia. There is thus a need to develop interventions aiming to prevent, reduce or eliminate such stereotypes. The aim of this study was to evaluate the effects of a documentary film on schizophrenia on cognitive, affective and behavioural aspects of stigmatisation. Methods: Forty-nine participants were assessed on measures of stereotypes and social distance, and on the Model of Stereotype Content, which includes measures of stereotypes, emotional reactions and behavioural tendencies. Participants were randomly assigned into either a condition in which they viewed the documentary film (Film group), or into a control condition in which no intervention was conducted (Control group). Results: Only participants in the Film group revealed a significant decrease of negative stereotypes (Dangerousness and Unpredictability) and desired Social distance, and a significant increase in the perception of sociability in persons with schizophrenia. Limitations: Small sample size and its reduced generalizability are the main limitations in this study. Conclusions: These findings suggest that a documentary film promoting indirect contact with people diagnosed with schizophrenia is a promising tool to prevent and reduce stigmatisation regarding schizophrenia. [less ▲]

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See detailThe effects of a documentary film on explicit and implicit aspects of stigmatisation towards people diagnosed with schizophrenia
Thonon, Bénédicte ULiege; Pletinx, Amandine; Grandjean, Allison et al

Poster (2015, May)

Background and Objectives: Stereotypes about schizophrenia may lead to prejudicial attitudes and discrimination with debilitating effects on people diagnosed with schizophrenia. There is thus a need to ... [more ▼]

Background and Objectives: Stereotypes about schizophrenia may lead to prejudicial attitudes and discrimination with debilitating effects on people diagnosed with schizophrenia. There is thus a need to develop interventions aiming to prevent, reduce or eliminate such stereotypes. The aim of this study was to evaluate the effects of a documentary film on schizophrenia on cognitive, affective and behavioural aspects of stigmatisation. Methods: Forty-nine participants were assessed on explicit measures of stereotypes and social distance, and on the Model of Stereotype Content (Fiske, Cuddy, Glick, & Xu, 2002), which includes measures of stereotypes, emotional reactions and behavioural tendencies. Furthermore, implicit affective attitudes were measured using the Affect Misattribution Procedure (Payne, Cheng, Govorum, & Stewart, 2005). Participants were randomly assigned into either a Film (who viewed the documentary film) or a Control group. Results: Only participants in the Film group revealed a significant decrease of negative stereotypes (Dangerousness and Unpredictability) and desired Social distance, and an increase in the perception of sociability in persons with schizophrenia. Limitations: No effects were found regarding the implicit measure. Conclusions: These findings suggest that a documentary film promoting indirect contact with people diagnosed with schizophrenia is a promising tool to prevent and reduce explicit aspects of stigmatisation regarding schizophrenia.  [less ▲]

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See detailEffects of a dust storm on the coupled Mars thermosphere ionosphere
Witasse, Olivier; Bougher, S. W.; Cerisier, Jean-Claude et al

Conference (2003)

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See detailEffects of a failure versus a submaximal low load blood flow-restriction training protocol on the Heat Shock Proteins responses
Hody, Stéphanie ULiege; Cumming, Kristoffer T.; Wernbom, Mathias et al

Poster (2016, August 27)

INTRODUCTION: The stress imposed to muscle fibers during blood flow restricted resistance exercise (BFRRE) is poorly investigated. Therefore, we aimed to compare the effect of a failure (FA) vs submaximal ... [more ▼]

INTRODUCTION: The stress imposed to muscle fibers during blood flow restricted resistance exercise (BFRRE) is poorly investigated. Therefore, we aimed to compare the effect of a failure (FA) vs submaximal (SU) BFRRE protocol on heat-shock protein responses in the exercising muscles. METHODS: Sixteen untrained men (18-45 yrs) completed 14 BFRRE sessions divided into 2 blocks of 7 sessions in 5 days, interspersed by 10 days of rest. Legs were randomly assigned to either FA (4 sets to voluntary failure) or SU protocol (30-, 15-, 15-, 15 reps) using unilateral knee extensions at 20% of 1 repetition maximum with 30s rest between sets. BFRRE was conducted with partial blood flow restriction (100 mmHg) induced by a 15 cm wide pressure cuff. Biopsies from the m. vastus lateralis were collected before, during and post intervention. The HSP response investigated was changes in αB-crystallin staining intensity on muscle cross sections analyzed by immunofluorescence. RESULTS: Relative to pre-exercise, a significant increase in αB-crystallin staining intensity (reflecting cytoskeletal bound proteins) was observed 2h after the first session in both legs (129 ± 18%, p<0.001 and 77 ± 10%, p<0.05; FA and SU, respectively). There were no significant difference between protocols at any time point, but these changes tended to be larger in FA legs than SU legs. During the rest period and 10 days post intervention, αB-crystallin staining intensity gradually decreased to baseline values. CONCLUSION: The αB-crystallin immunostaining analyses suggest that cytoskeletal proteins are highly stressed after the first session of both FA and SU BFRRE protocols. [less ▲]

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See detailEffects of a giant exercising board game intervention on ambulatory physical activity among nursing home residents: a preliminary study
Mouton, Alexandre ULiege; Gillet, Nicolas; Mouton, Flore et al

in Osteoporosis International (2017), 28(S1), 318

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See detailEffects of a giant exercising board game intervention on ambulatory physical activity among nursing home residents: a preliminary study
Mouton, Alexandre ULiege; Gillet, Nicolas; Mouton, Flore et al

Conference (2017, July 08)

Purpose: This study examined the effects of a giant (4 meters by 3 meters) exercising board game intervention on ambulatory physical activity (PA) and on a broader array of physical and psychological ... [more ▼]

Purpose: This study examined the effects of a giant (4 meters by 3 meters) exercising board game intervention on ambulatory physical activity (PA) and on a broader array of physical and psychological outcomes among nursing home residents. Materials and methods: A quasi-experimental longitudinal study was carried out in two comparable nursing homes. Ten participants (aged 82.5 ± 6.3 and comprising 6 women) meeting the inclusion criteria took part to the one-month intervention in one nursing home, whereas eleven participants (aged 89.9 ± 3.1 with 8 women) were assigned to the control group in the other nursing home. The giant exercising board game required participants to perform strength, flexibility, balance and endurance activities. The assistance provided by an exercising specialist decreased gradually during the intervention in an autonomy-oriented approach, based on the self-determination theory (SDT). The following were assessed at baseline, after the intervention and after a follow-up period of three months: PA (steps/day and energy expenditure/day with ActiGraph, GT3X+), cognitive status (MMSE), quality of life (EQ-5D), motivation for PA (BREQ-2), gait and balance (Tinetti and SPPB), functional mobility (Timed Up and Go) and the muscular isometric strength of the lower limb muscles. Results and conclusions: In the intervention group, PA increased from 2921 steps/day at baseline to 3358 steps/day after the intervention (+14.9%, p = 0.04) and 4083 steps/day (+39.8%, p = 0.03) after three months. Energy expenditure/day also increased after the intervention (+110 kcal/day, +6.3%, p = 0.01) and after three months (+219 kcal/day, +12.3%, p = 0.02). Quality of life (p < 0.05), balance and gait (p < 0.05), and strength of the ankle (p < 0.05) were also improved after three months. Such improvements were not observed in the control group. The preliminary results are promising but further investigation is required to confirm and evaluate the longterm effectiveness of PA interventions in nursing homes [less ▲]

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See detailEffects of a giant exercising board game intervention on ambulatory physical activity among nursing home residents: a preliminary study
Mouton, Alexandre ULiege; Gillet, Nicolas; Mouton, Flore et al

in Clinical Interventions in Aging (2017), 12

Purpose: This study examined the effects of a giant (4×3 m) exercising board game intervention on ambulatory physical activity (PA) and a broader array of physical and psychological outcomes among nursing ... [more ▼]

Purpose: This study examined the effects of a giant (4×3 m) exercising board game intervention on ambulatory physical activity (PA) and a broader array of physical and psychological outcomes among nursing home residents. Materials and methods: A quasi-experimental longitudinal study was carried out in two comparable nursing homes. Ten participants (aged 82.5±6.3 and comprising 6 women) meeting the inclusion criteria took part in the 1-month intervention in one nursing home, whereas 11 participants (aged 89.9±3.1 with 8 women) were assigned to the control group in the other nursing home. The giant exercising board game required participants to perform strength, flexibility, balance and endurance activities. The assistance provided by an exercising specialist decreased gradually during the intervention in an autonomy-oriented approach based on the self-determination theory. The following were assessed at baseline, after the intervention and after a follow-up period of 3 months: PA (steps/day and energy expenditure/day with ActiGraph), cognitive status (mini mental state examination), quality of life (EuroQol 5-dimensions), motivation for PA (Behavioral Regulation in Exercise Questionnaire-2), gait and balance (Tinetti and Short Physical Performance Battery), functional mobility (timed up and go), and the muscular isometric strength of the lower limb muscles. Results and conclusion: In the intervention group, PA increased from 2,921 steps/day at baseline to 3,358 steps/day after the intervention (+14.9%, P=0.04) and 4,083 steps/day (+39.8%, P=0.03) after 3 months. Energy expenditure/day also increased after the intervention (+110 kcal/day, +6.3%, P=0.01) and after 3 months (+219 kcal/day, +12.3%, P=0.02). Quality of life (P,0.05), balance and gait (P,0.05), and strength of the ankle (P,0.05) were also improved after 3 months. Such improvements were not observed in the control group. The preliminary results are promising but further investigation is required to confirm and evaluate the long-term effectiveness of PA interventions in nursing homes. [less ▲]

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