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See detailLa fonction de Cantor
Simons, Laurent ULg

Master's dissertation (2009)

Ce mémoire est une introduction à l'étude de la bijection de Cantor, bijection entre l'intervalle unité et le carré unité.

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See detailFonction de référent hospitalier pour la continuité des soins : une démarche d’aide à la décision
Gosset, Christiane ULg; Moons, Philippe; Pasquasy, Nathalie

Report (2005)

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See detailFonction de Riemann généralisée
Simons, Laurent ULg; Bastin, Françoise ULg; Nicolay, Samuel ULg

Conference (2014, September 22)

Dans cet exposé, nous étudions la régularité de la fonction de Riemann généralisée~$R_{\alpha,\beta}$ (avec $\alpha>1$ et $\beta>0$) définie par \[ R_{\alpha,\beta}(x)=\sum_{n=1}^{+\infty}\frac{\sin(\pi n ... [more ▼]

Dans cet exposé, nous étudions la régularité de la fonction de Riemann généralisée~$R_{\alpha,\beta}$ (avec $\alpha>1$ et $\beta>0$) définie par \[ R_{\alpha,\beta}(x)=\sum_{n=1}^{+\infty}\frac{\sin(\pi n^\beta x)}{n^\alpha},\quad x\in\R. \] En particulier, nous déterminons son exposant de Hölder uniforme. Pour terminer, nous analysons le comportement de~$R_{\alpha,\beta}$ lorsque le paramètre $\alpha$ ou $\beta$ tend vers l'infini. Cet exposé est basé sur un travail en collaboration avec F. Bastin et S. Nicolay. [less ▲]

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See detailLa fonction endocrinienne et métabolique du poumon
Lamy, Maurice ULg; Faymonville, Marie ULg; Deby, Ginette ULg et al

in La pathologie respiratoire en anesthésie-réanimation (1984)

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See detailFonction et signification de l'image égyptienne
Laboury, Dimitri ULg

in Bulletin de la Classe des Beaux-Arts de l'Académie Royale de Belgique, 6e série (1998), IX

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See detailLa fonction exponentielle : premières propriétés
Bair, Jacques ULg; Henry, Valérie ULg

in Tangente Sup (2013), 69

Nous passons en revue différentes façons d'introduire des fonctions exponentielles et logarithmes, montrant notamment comment procédait Euler en exploitant des infinitésimaux.

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See detailLa fonction guidage en micromécanique
Merken, Patrick; Debongnie, Jean-François ULg

Book published by DEBONGNIE (JEAN-FRANCOIS) (2010)

1) Modelling the stiffness of a circular notch hinge subjected to flexure, torsion or shear : asymptotic values for a vanishing thickness and correction factors for the general case. 2) Flexible membrane ... [more ▼]

1) Modelling the stiffness of a circular notch hinge subjected to flexure, torsion or shear : asymptotic values for a vanishing thickness and correction factors for the general case. 2) Flexible membrane : stiffness for vanishing radius ratio and correction factor for the general case. 3) Conclusion. 4) Appendices, including a summary of useful formulae. [less ▲]

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See detailLa fonction mitochondriale des cellules musculaires squelettiques équines en culture : effet de l'anoxie et des neutrophiles activés.
Ceusters, Justine ULg

Doctoral thesis (2012)

Introduction Horses are known to be remarkable athletes. However, to realize such repeated intense exercises, as competition horses do, and could also became a stressing condition leading to muscular ... [more ▼]

Introduction Horses are known to be remarkable athletes. However, to realize such repeated intense exercises, as competition horses do, and could also became a stressing condition leading to muscular dysfunctions but could also decrease their performances. In horses, lesions from ischemia/reperfusion are found in numerous clinical situations but also during intense exercise, the muscular oxygenation decreasing as a function of the exercise intensity. But it is during the reoxygenation, with the subsequent increase of the electron flux within the mitochondrial respiratory electron transport chain at the cessation of exercise, that an important increase of the reactive oxygen and nitrogen species (RNOS) production will be observed. The realization of such intense exercise provokes also an important systemic inflammatory reaction. Recently, some studies realized by our group on competing horses showed that intense exercise can activate the polymorphonuclear neutrophils (PMNs) which degranulate their myeloperoxidase (MPO) and elastase (ELT). The increase of MPO was not only plasmatic but also muscular, where it was associated with a decrease of the mitochondrial complex I activity, showing there a possible link between the MPO activity and the mitochondrial dysfunction in horses performing exercise. The relationship between ischemia/reperfusion, ROS production from mitochondria, muscular damages and inflammatory reaction is largely unexplored in horses. The principal objectives of this work were to study, on a primary culture of equine skeletal muscle cells obtained from muscular microbiopsies, the effect of anoxia/reoxygenation (A/R) and/or of MPO on their ROS production and mitochondrial respiratory function. Results Primary culture of equine skeletal muscle cells from muscular microbiopsies With muscular microbiopsies, we developed an efficient and convenient sampling method, usable in current practice and even on high level competing horses. By using the microbiopsies as explants, we obtained a primary culture of skeletal muscle cells, a suitable experimental model for the in vitro study of equine muscular function. Model of anoxia/reoxygenation applied on cultured equine skeletal muscle cells Thanks to the primary culture, we showed by fluorescence spectroscopy and gas chromatography, an increased ROS production by adherent cells submitted to 2 h of A/R. For the following investigations, 2 other models were designed on detached cells : a first one of cyclic A/R (2 x 30 min) and a second one of a single long period of 1 h, 2 h or 3 h of A/R. The first one showed a decrease of the routine respiration, but also of ROS production and of the mitochondrial complex I specific activity of the cells submitted to cyclic A/R. After a single long period of A/R, on the contrary, the routine respiration, the ROS production and the mitochondrial complex I specific activity of the cells were increased while the ATP production by these cells was decreased. This observation, arguing for an uncoupling of the oxidative phosphorylation, prompted us to investigate the uncoupling protein 3 (UCP3) expression by cultured cells. The indirect immunofluorescence, as well as the electrophoresis coupled with the western blot, showed that they expressed UCP3, in normoxia and after 2 h of A/R, but also that this expression varied as a function of the duration of the A/R, with a maximum observed for 2 h. The oxygraphic phosphorylation control protocol (PCP) applied on detached cells showed an increase of their routine but also of their non phosphorylating (after ATP synthase inhibition) respirations after a single long period of 2 h A/R. Their maximal respiratory capacity, per contra, decreased significantly. When regarding the flux control ratios (FCR, related to maximal respiratory capacity), we confirmed that cells submitted to 2 h of A/R need to function more to keep stable their energetic state (increase of the part of their maximal respiratory capacity used for oxidative phosphorylation because of a lesser efficiency). Inflammatory model Equine neutrophils activation in whole blood All the activation systems used, 12-phorbol 13-myristate acetate (PMA), cytochalasin B with N-formyl-methionyl-leucyl-phenylalanine (CB/fMLP), tumor necrosis factor-alpha (TNF- α), lipopolysaccharides (LPS) and LPS with TNF-α, induced a significant degranulation of total MPO by the PMNs activated in whole blood. Only the combinations CB/fMLP and LPS/TNF-α caused a significant release of active MPO. For the release of ELT by activated PMNs, only the action of the PMA was significant. Use of purified active equine MPO Initially, we showed that MPO incubated with equine skeletal muscle cells was able to bind to the cell membranes, but furthermore, thanks to the differential centrifugation protocol, that we demonstrated that it was able to enter within the cells, because we found it in the cytosolic fraction. Our following experiences showed that it was able, even alone, to increase the ROS produced by the cells, as demonstrated by fluorescence and gas chromatography. Furthermore, MPO worked harder than Horseradish peroxidase (HRP), our "peroxidasic control". The MPO seemed also to alter the mitochondrial respiratory function of cultured cells. Anyway, thanks to the oxygraphic PCP protocol, we showed that MPO alone decreased mostly their routine respiration and their maximal respiratory capacity. Paradoxically, we seen that it increased the part of the maximal respiratory capacity used for routine and non phosphorylating respirations. The second oxygraphic protocol, designed on permeabilized cells, seems to confirm these observations. Compared to control cells, the MPO-treated cells had a increased non phosphorylating respiration and a decreased maximal respiratory capacity, particularly via the mitochondrial complex I. Combined model: anoxia/reoxygenation in inflammatory conditions With fluorescence spectroscopy as well as with gas chromatography, the MPO amplifies the ROS production already increased with the A/R alone. Furthermore, with a 3,3-diaminobenzidine (DAB) coloration, we showed the persistence of the MPO (and of the HRP), within the cells, even after 2 h of A/R. The oxygraphic PCP protocol confirms that MPO seems to exacerbate the damage initiated by A/R. Thus, compared to what we observed with A/R alone, the addition of MPO causes a further decrease of the routine respiration and the maximal respiratory capacity of the cells and increases their non phosphorylating respiration. These observations, along the lines of an important mitochondrial dysfunction, were confirmed when regarding the FCR. Thus, MPO-treated cells, submitted to A/R need to use a greater part of their maximal respiratory capacity for routine respiration, but a greater part of it was also used for non efficient respiration. So, these cells need to work more intensely to keep stable their energetic state, what is reflected in our protocol by an increased part of the maximal respiratory capacity used for oxidative phosphorylation compared to what we observed after A/R alone. Conclusion and perspectives During intense exercise, some physiopathological conditions, inducing important mitochondrial and energetic alterations, seem to gather within the muscle of sport horses. As showed by our work, because of its implication in the mitochondrial regulation at the respiratory level as well as for RNOS production, and of its particular sensibility to nitration, the mitochondrial complex I could play a pivotal role. Although our results clearly indicate that MPO, by exacerbating the deleterious effects of A/R, is detrimental to cellular and mitochondrial functions, further precisions are needed to confirm the specific implication of mitochondrial complex I in the observed phenomena. The results obtained by our group in vivo on competing horses lead the way in this direction but, the adaptation of the oxygraphic protocol on permeabilized cells, combining A/R with the action of MPO, will help to confirm, in vitro, the hypothesis. On another way, the effect of nitration or nitrosation on the mitochondrial complex I will need to be further investigated. Finally, to consider in a largest way the action of the PMNs on the mitochondrial function, it will be interesting to use the whole blood model of PMNs activation in co-culture with equine skeletal myoblasts. By this way, the action of other inflammatory factors or mediators could be studied in conditions nearly to the ones observed in vivo. [less ▲]

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See detailLa fonction neuroendocrine du thymus
Geenen, Vincent ULg

Conference given outside the academic context (1986)

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See detailLa fonction neuroendocrinienne du thymus
Geenen, Vincent ULg

in Revue Médicale de Liège (1986), XLI

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See detailLa fonction paternelle dans la société contemporaine
Naziri, Despina ULg

Conference given outside the academic context (2000)

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See detailFonction pulmonaire de la chèvre : normes et spécificités
Bakima, M.; Arendt, J.; Lomba, F. et al

in Annales de Médecine Vétérinaire (1991), 135

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See detailLa fonction récréative de la forêt wallonne : évaluation et pistes de réflexion pour son intégration optimale dans l'aménagement intégré des massifs
Colson, Vincent ULg; Lejeune, Philippe ULg; Rondeux, Jacques ULg

in Forêt Wallonne (2009), (101), 3-17

Dans le contexte d’une gestion multifonctionnelle de la forêt, il importe d’intégrer la fréquentation du public dans les démarches d’aménagement. Encore faut-il pouvoir se baser sur des éléments objectifs ... [more ▼]

Dans le contexte d’une gestion multifonctionnelle de la forêt, il importe d’intégrer la fréquentation du public dans les démarches d’aménagement. Encore faut-il pouvoir se baser sur des éléments objectifs. C’est ce que propose de cerner cette synthèse d’une thèse de doctorat menée à la Faculté universitaire des Sciences agronomiques de Gembloux qui a, entre autre, révélé l’ampleur et la valeur de la fonction récréative des forêts en Wallonie. [less ▲]

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See detailLa fonction récréative des massifs forestiers wallons : analyse et évaluation dans le cadre d'une politique forestière intégrée
Colson, Vincent ULg

Doctoral thesis (2009)

An analysis of forest recreation in Wallonia has been carried out. The originality of the approach resides mainly in the fact that a regional scale was used. The precise meaning of “forest recreation” was ... [more ▼]

An analysis of forest recreation in Wallonia has been carried out. The originality of the approach resides mainly in the fact that a regional scale was used. The precise meaning of “forest recreation” was clarified by limiting it to the non benefit services. The analysis of the public demand was performed by means of three main surveys: a phone survey based on a sample of the Walloon and Brussels population, a survey within 40 woodlands (during 6 periods) and, finally, a survey conducted among managers of Forest Service districts in order to map the visitation level of all Walloon woodlands. Data concerning the recreational supply of the Walloon forest have been gathered as well. These data concerning supply and demand were used to create a model capable of forecasting the number of visits for the whole Walloon forest according to local population, one day tourists and holidaymakers. An economic assessment of these visits and the whole recreational function of the Walloon forest was made by adapting two methods (travel costs and the contingent valuation method) to the Walloon regional context and to the available data. All these investigations provided the quantification of the importance of the recreational function at a regional level as well as highlighting local variations. Recommendations related to the taking into account of forest recreation in forest policy, both at the regional level and at the local level were therefore proposed. [less ▲]

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See detailLa fonction régulatrice de l'évaluation vue sous l'angle de l'implication de l'étudiant
Leclercq, Dieudonné ULg

in Education - Tribune libre (1976), 159

L'auteur définit le degré d'implication et d'autonomie de l'étudiant dans le processus de régulation de son apprentissage comme les rôles qu'il assume dans les diverses opérations de ce processus régulé ... [more ▼]

L'auteur définit le degré d'implication et d'autonomie de l'étudiant dans le processus de régulation de son apprentissage comme les rôles qu'il assume dans les diverses opérations de ce processus régulé : la fixation des buts (les objectifs), la définition du dispositif (méthodes, évaluations, agents, ressources, lieux, timing), l'exécution de la performance, l'observation (mesure), les décisions de régulation (planification, rétroactions...). Le lien est fait avec des "Modules d'auto-évaluation". [less ▲]

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See detailLa fonction rénale au cours de la grossesse normale
Rorive, Georges ULg; Krzesinski, Jean-Marie ULg; Carlier, P. G.

in Rein et grossesse (1984)

L'état de gravidité est caractérisé par des modifications remarquables de la fonction rénale. C'est la seule situation clinique ou le flux plasmatique rénal et la filtration glomérulaire augmentent de ... [more ▼]

L'état de gravidité est caractérisé par des modifications remarquables de la fonction rénale. C'est la seule situation clinique ou le flux plasmatique rénal et la filtration glomérulaire augmentent de plus de 50 % pour une période de longue durée. Le mécanisme de ces modifications a largement profite de modèles expérimentaux. Le rôle des secrétions hormonales, et de la synthèse accrue de prostaglandines, caractéristiques de la grossesse parait primordial. Simultanement , on relève chez la femme enceinte des adaptations de la fonction tubulaire qui vont rendre compte d'une excrétion urinaire accrue de glucose, d'acides aminés et d'acide urique. Enfin, la grossesse s'accompagne d'une expansion des espaces extravasculaires. Cette modification est associée a une hypersécrétion de renine, d'aldosterone et de desoxycorticosterone. Parallèlement, on observe une résistance a l'effet vasoconstricteur de l'angiotensine II. Ces altérations paraissent indispensables au deroulement normal de la grossesse et à.un dévéloppement optimal du fœtus. La grossesse se caractérise par des modifications remarquables de la fonction rénale, de l'équilibre hydro-minéral ainsi que des adaptations importantes sur le plan hemodynamique. Ces modifications sont évidemment interdependantes, sans qu'il soit à ce jour aise de définir quelle est l'alteration initiale: rénale , endocrinienne ou cardiovasculaire. Pour des raisons purement pratiques, nous traiterons successivement chacun de ces aspects en insistant chaque fois que cela est possible sur les répercussions d'une altération d'un système sur les deux autres . [less ▲]

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