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See detailFDC : origin and function
Heinen, Ernst ULg; Bosseloir, A.; Bouzahzah, F. et al

in Current topics in Microbiology and Immunology (1995)

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See detailFDC-B1, a new monoclonal antibody directed against bovine follicular dendrititic cells.
Defaweux, Valérie ULg; Mélot, France ULg; Jolois, Olivier ULg et al

Poster (2003, March)

Follicular dendritic cells (FDCs) are unique immunological accessory cells located in the light and dark zones of the germinal centres in lymph follicles. Characterized by long branching processes forming ... [more ▼]

Follicular dendritic cells (FDCs) are unique immunological accessory cells located in the light and dark zones of the germinal centres in lymph follicles. Characterized by long branching processes forming a three-dimensional network, FDCs create particular microenvironments for germinal centre B and T cells and contribute to the maturation of B cells into memory cells. An involvement of the FDCs is suspected in various disorders affecting lymphoid tissues, malignant lymphoma or in some viral diseases. Moreover, in prion diseases, FDCs seem to be the major sites of extraneuronal cellular prion protein expression and the principal sites of the infectious agent accumulation in lymph organs. Because no antibody commercially available was specific to bovine FDCs, a new monoclonal antibody directed against bovine FDCs (FDC-B1) has been produced and characterized in our laboratory. The antigen detected by FDC-B1 is expressed on FDC surfaces in ruminant (bovine, ovine and caprine) lymphoid organs. This protein seems to be a membrane glycoprotein of more or less 28 kDa whose sequence will be soon determined. Moreover, FDC-B1 can be used in various applications: immunofluorescence, immunoperoxidase, immunogold labellings and western blotting. FDCs are potential targets for therapy or prophylaxis in natural TSEs, such as bovine spongiform encephalopathies and scrapie. Thus, it appears of great interest to identify bovine and ovine FDCs in routine lymphoid tissues sections. An other application of this antibody to immunofluorescence histochemistry techniques will enable the study of possible direct contacts between bovine FDCs and nerve endings and thus clarify prions neuroinvasion scheme in the case of BSE and scrapie. [less ▲]

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See detailFDC-B1: a new monoclonal antibody directed against bovine follicular dendritic cells
Defaweux, Valérie ULg; Mélot, France ULg; Jolois, Olivier ULg et al

in Veterinary Immunology and Immunopathology (2004), 97(1-2), 1-9

Follicular dendritic cells (FDCs) are a unique population of accessory cells located in the light zone of the germinal centres of lymphoid follicles. Their involvement in the generation of Immoral immune ... [more ▼]

Follicular dendritic cells (FDCs) are a unique population of accessory cells located in the light zone of the germinal centres of lymphoid follicles. Their involvement in the generation of Immoral immune responses implies a potential role for these cells in many disorders. Indeed, in prion diseases, FDCs seem to be the major sites of extraneuronal cellular prion protein expression and the principal sites of the infectious agent accumulation in lymphoid organs. The identification of FDC is useful for the analysis of their distribution in reactive lymphoid tissue as well as in pathological conditions. The production and characterisation of a new mouse monoclonal antibody directed against bovine follicular dendritic cells (FDC-B1) is reported. The antigen detected by FDC-B1 is expressed exclusively on the surface of FDCs in ruminant lymphoid organs. The antigen has an approximate molecular weight of 28 kDa. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailLe FDF dans les provinces et les entités fédérées
Lanneau, Catherine ULg

in Dujardin, Vincent; Delcorps, Vincent (Eds.) FDF. 50 ans d’engagement politique (2014)

Cette contribution analyse l’action du FDF, parti « communautaire » essentiellement bruxellois, dans les entités fédérées. Quel rôle a-t-il joué, seul ou en partenariat avec le RW puis les libéraux, à la ... [more ▼]

Cette contribution analyse l’action du FDF, parti « communautaire » essentiellement bruxellois, dans les entités fédérées. Quel rôle a-t-il joué, seul ou en partenariat avec le RW puis les libéraux, à la Communauté française ? Comment s’est articulé son combat pour une région bruxelloise et dans quelle mesure y a-t-il appliqué son programme depuis 1989 ? Quelle est l’action de son seul député au Parlement flamand ? Le FDF a-t-il réussi à dépasser son image de parti protestataire, focalisé sur les thématiques linguistiques, pour se positionner en mouvement « urbain et culturel », se définissant comme « réformateur social » ? Nous nous appuyons sur les archives du parti, ses publications internes, les sources officielles émanant des régions et communautés mais également la presse quotidienne et magazine. [less ▲]

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See detailFDG PET/CT for diagnostic arterial prosthetic graft infection : preliminary report.
NAMUR, Gauthier ULg; VAN DAMME, Hendrik ULg; BECKERS, Catherine ULg et al

in PROCEEDINGS OF XIIIth SYMPOSIUM OF THE BELGIAN SOCIETY OF NUCLEAR MEDICINE (2007, May)

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See detailFDG PET/CT for rectal carcinoma radiotherapy treatment planning : Comparison of functional volume delineation algorithms and clinical challenges.
WITHOFS, Nadia ULg; BERNARD, Claire ULg; VAN DER REST, Catherine ULg et al

in Journal of Applied Clinical Medical Physics (2014), 15(5), 216-228

PET/CT imaging could improve delineation of rectal carcinoma gross tumor volume (GTV) and reduce interobserver variability. The objective of this work was to compare various functional volume delineation ... [more ▼]

PET/CT imaging could improve delineation of rectal carcinoma gross tumor volume (GTV) and reduce interobserver variability. The objective of this work was to compare various functional volume delineation algorythms. [less ▲]

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See detailFDG PET/CT in Crohn's disease: correlation of quantitative FDG PET/CT parameters with clinical and endoscopic surrogate markers of disease activity.
Saboury, Babak; Salavati, Ali; Brothers, Alex et al

in European journal of nuclear medicine and molecular imaging (2013)

PURPOSE: The aim of this study was to determine the feasibility and potential clinical utility of assessment of Crohn's disease (CD) activity by 18F-fluorodeoxyglucose (FDG) positron emission tomography ... [more ▼]

PURPOSE: The aim of this study was to determine the feasibility and potential clinical utility of assessment of Crohn's disease (CD) activity by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT employing a new quantitative approach. METHODS: A total of 22 subjects (mean age 37) with CD who had undergone FDG PET/CT followed by ileocolonoscopy within 1 week were included in this analysis. The CD endoscopy index of severity (CDEIS) for various bowel segments was calculated. The CD activity index (CDAI) was evaluated, and fecal calprotectin was measured. On PET, regions with increased FDG uptake in large bowel were segmented with an adaptive contrast-oriented thresholding algorithm, and metabolically active volume (MAV), uncorrected mean standardized uptake value (SUVmean), partial volume-corrected SUVmean (PVC-SUVmean), SUVmax, uncorrected total lesion glycolysis (TLG = MAV x SUVmean), and PVC total lesion glycolysis (PVC-TLG = MAV x PVC-SUVmean) were measured. Global CD activity score (GCDAS) was calculated as the sum of PVC-TLG over all clinically significant FDG-avid regions in each subject. Correlations between regional PET quantification measures (SUVs, TLGs) and CDEIS were calculated. Correlations between the global PET quantification measure (GCDAS, global SUVs) with CDAI, fecal calprotectin, CDEIS, and CRP level were also calculated. RESULTS: SUVmax, PVC-SUVmean, and PVC-TLG significantly correlated with segment CDEIS subscores (r = 0.50, r = 0.69, and r = 0.31, respectively; p < 0.05). GCDAS significantly correlated with CDAI and fecal calprotectin (r = 0.64 and r = 0.51, respectively; p < 0.05). CONCLUSION: By employing this new quantitative approach, we were able to calculate indices of regional and global CD activity, which correlated well with both clinical and pathological disease activity surrogate markers. This approach may be of clinical importance in measuring both global disease activity and treatment response in patients with CD. [less ▲]

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See detailFDG-PET and lung cancer: evaluation of solitary pulmonary nodule and mediastinal staging.
PAULUS, P.; HUSTINX, Roland ULg; BURY, Thierry ULg et al

in Proceedings of the VIIth International PET Conference, Institute for Clinical PET (1996)

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See detailFDG-PET for the routine follow-up in NHL: First prospective evaluation
Jerusalem, Guy ULg; Silvestre, R.; Beguin, Yves ULg et al

in Journal of Clinical Oncology (2006, June 20), 24(18, Part 1 Suppl. S), 439

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See detailFDG-PET imaging for assessing pleural malignancy : a semi-quantitative analysis.
LAROCK, Marie-Paule ULg; DUYSINX, Bernard ULg; NGUYEN, D. et al

in Journal of Nuclear Medicine (The) (2005), 46(SUPPL), 426

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See detailFDG-PET imaging for diagnosing bone infection.
LETESSON, G.; FOIDART-WILLEMS, Jacqueline ULg; HUSTINX, Roland ULg

in Journal of Nuclear Medicine (The) (2005), 46(SUPPL), 323

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See detailFDG-PET imaging for monitoring rheumatoid arthritis treated by infliximab injections.
BECKERS, Catherine ULg; RIBBENS, Clio ULg; ANDRE, Béatrice ULg et al

in Journal of Nuclear Medicine (The) (2002), 43

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See detailFe and Mg Isotope Fractionation in Olivine from the NWA 1068 Shergottite
Collinet, Max ULg; Charlier, Bernard ULg; Namur, Olivier et al

Conference (2014, June 09)

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See detailFE modelling of anorthosite diapirism: the Egersund-Ogna massif, South Norway
Hoffer, B.; Barnichon, J.-D.; Charlier, Robert ULg et al

in Proc. of the Int. Meeting on Deformation Mechanisms in nature and experiments (1997, March)

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See detailFe(II)2.67Fe(III)4(PO4)5.35(HPO4)0.65 and Fe(II)2.23Fe(III)4(PO4)4.45(HPO4)1.55, two new mixed-valence iron phosphates.
Dal Bo, Fabrice ULg; Hatert, Frédéric ULg

in Acta Crystallographica Section C-Crystal Structure Communications (2012), C68

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See detailFe-2(II)(PO4)(OH), a synthetic analogue of wolfeite
Hatert, Frédéric ULg

in Acta Crystallographica Section C-Crystal Structure Communications (2007), 63(Part 12), 119-121

This paper reports the hydrothermal synthesis and crystal structure refinement of diiron(II) phosphate hydroxide, Fe-2(II)(PO4)(OH), obtained at 1063 K and 2.5 GPa. This phosphate is the synthetic ... [more ▼]

This paper reports the hydrothermal synthesis and crystal structure refinement of diiron(II) phosphate hydroxide, Fe-2(II)(PO4)(OH), obtained at 1063 K and 2.5 GPa. This phosphate is the synthetic analogue of the mineral wolfeite, and has a crystal structure topologically identical to those of minerals of the triplite-triploidite group. The complex framework contains edge-and corner-sharing FeO4(OH) and FeO4(OH)(2) polyhedra, linked via corner-sharing to the PO4 tetrahedra (average P-O distances are between 1.537 and 1.544 angstrom). Four five-coordinated Fe sites are at the centers of distorted trigonal bipyramids (average Fe-O distances are between 2.070 and 2.105 angstrom), whereas the coordination environments of the remaining Fe sites are distorted octahedra (average Fe-O distances are between 2.146 and 2.180 angstrom). The Fe-O distances are similar to those observed in natural Mg-rich wolfeite, except for two Fe-O bond distances, which are significantly longer in synthetic Fe-2(2+) (PO4)(OH). [less ▲]

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See detailFe-57 Mossbauer spectral and muon spin relaxation study of the magnetodynamics of monodispersed gamma-Fe2O3 nanoparticles
Rebbouh, Leila; Hermann, Raphaël ULg; Grandjean, Fernande ULg et al

in Physical Review b (2007), 76(17),

The Mossbauer spectra of monodispersed iron oxide nanoparticles with diameters of 4, 7, 9, and 11 nm have been measured between 4.2 and 315 K and fitted within the formalism for stochastic fluctuations of ... [more ▼]

The Mossbauer spectra of monodispersed iron oxide nanoparticles with diameters of 4, 7, 9, and 11 nm have been measured between 4.2 and 315 K and fitted within the formalism for stochastic fluctuations of the hyperfine Hamiltonian. In this model, the hyperfine field is assumed to relax between the six +/- x, +/- y, and +/- z directions in space with a distribution of relaxation rates that is temperature dependent. Muon spin relaxation measurements have been carried out on the 9 nm particles between 4.2 and 295 K. Both techniques reveal three regimes in the magnetic dynamics of these nanoparticles. In the low-temperature regime, between 4.2 and similar to 30 K, the nanoparticle magnetic moments are blocked and a spin-glass-like state is observed with nearly static hyperfine fields, as is indicated by the well resolved magnetic Mossbauer spectra and the slow exponential decay of the muon asymmetry functions. In the high-temperature regime, above similar to 125 K, the nanoparticle magnetic moments and, hence, the hyperfine fields, relax rapidly and a typical thermally activated superparamagnetic behavior is observed, as is indicated by the Mossbauer doublet line shape and the muon asymmetry functions that are unquestionably characteristic of monodispersed nanoparticles. In the intermediate regime between similar to 30 and 125 K, the Mossbauer spectra are the superposition of broad sextets and doublets and the muon asymmetry functions have been fitted with a sum of two terms, one relaxing term similar to that observed at and above 125 K and one term characteristic of static local fields. Hence, in this intermediate regime, the sample is magnetically inhomogeneous and composed of nanoparticles rapidly and slowly relaxing as a result of interparticle interactions. The magnetic anisotropy constants determined from both the Mossbauer spectral and magnetic susceptibility results decrease by a factor similar to 4 with increasing diameter from 4 to 22 nm and increase linearly with the percentage of iron(III) ions present at the surface of the nanoparticles. The interparticle interaction energy is estimated to be between 89 and 212 K from the temperature dependence of the magnetic hyperfine field measured on the 9 nm nanoparticles. [less ▲]

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