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See detailEvidence-based practice: fondements et réflexions sur l’apport en clinique.
Maillart, Christelle ULg; Durieux, Nancy ULg

in Langage et Pratiques (2014), 53

L’evidence-based practice ou pratique basée sur les preuves est une approche de plus en plus encouragée en logopédie au niveau international. Cet article présente les principaux composants en détaillant ... [more ▼]

L’evidence-based practice ou pratique basée sur les preuves est une approche de plus en plus encouragée en logopédie au niveau international. Cet article présente les principaux composants en détaillant la nature des preuves liées aux trois piliers de l’EBP (preuves externes, preuves internes ou préférences du patient). La démarche de l’EBP est brièvement discutée ainsi que les freins et les bénéfices attendus en clinique. [less ▲]

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See detailEvidence-based semiquantitative methodology for prioritization of foodborne zoonoses.
Cardoen, Sabine; Van Huffel, Xavier; Berkvens, Dirk et al

in Foodborne Pathogens and Disease (2009), 6(9), 1083-96

OBJECTIVES: To prioritize an extended list of food- and water-borne zoonoses to allow food safety authorities to focus on the most relevant hazards in the food chain. METHODS: An evidence-based ... [more ▼]

OBJECTIVES: To prioritize an extended list of food- and water-borne zoonoses to allow food safety authorities to focus on the most relevant hazards in the food chain. METHODS: An evidence-based semiquantitative methodology was developed. Scores were given by 35 scientific experts in the field of animal and public health, food, and clinical microbiology and epidemiology to 51 zoonotic agents according to five criteria related to public health (severity and occurrence in humans), animal health (severity of disease coupled with economic consequences and occurrence in animals), and food (occurrence in food). The scoring procedure was standardized and evidence-based as experts were provided, for each zoonotic agent, a same set of up-to-date help information data related to the five criteria. Independently, the relative importance of the five criteria was weighted by seven food chain risk managers. The zoonotic agents were ranked based on overall weighted scores and were grouped in four statistically different levels of importance. RESULTS: The following foodborne zoonotic pathogens were classified as "most important": Salmonella spp., Campylobacter spp., Listeria monocytogenes, and verocytotoxigenic Escherichia coli. A second group of "significant importance" included Toxoplasma gondii, the agent of bovine spongiform encephalopathy, Clostridium botulinum, Staphylococcus aureus, Cryptosporidium parvum, Mycobacterium bovis, Echinococcus granulosus, Streptococcus spp., Echinococcus multilocularis, Yersinia enterocolitica, Mycobacterium avium, Fasciola hepatica, Giardia intestinalis, and Rotavirus. CONCLUSIONS: This methodology allowed to rank 51 zoonotic agents with objectivity and taking account of a combined input from risk assessors and risk managers. Applications: These results support food safety policy makers to establish the multiannual monitoring program of foodborne zoonoses. They also enable to identify knowledge gaps on specific zoonotic agents and to formulate key research questions. Principally, this method of prioritization is of general interest as it can be applied for any other ranking exercise and in any country. [less ▲]

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See detailEvidence-Based Veterinary Medicine
Pasleau, Françoise ULg; Vandenput, Sandrina ULg; Fairon, Nicolas ULg et al

Conference (2004, September 24)

At the University of Liege, the medical library recently merged with several entities including the libraries of Zoology, Botany, Psychology and Veterinary Medicine. Everywhere, the librarians are ... [more ▼]

At the University of Liege, the medical library recently merged with several entities including the libraries of Zoology, Botany, Psychology and Veterinary Medicine. Everywhere, the librarians are involved in teaching activities and users training programs are rather well developped in every field. But the comparison of the curriculum contents points to a few amazing differences. The most surprising one is the approach of Evidence-Based Medicine (EBM). The concept is well introduced in the medical community and it is a legal obligation for the medical students to be thaught in and to practice EBM. Surprisingly, the veterinarians don't seem very interested. Besides its impact on clinical practice, EBM is a good opportunity to create new habits that are valuable for continuing education and to develop critical appraisal skills. Thus, we wish to analyze the reasons that might explain why EBM seems to be left aside at the Faculty of Veterinary Medicine. Two approaches are envisionned. First, we plan to ask the Faculty itself about its position regarding the concept. Surveys and interviews will be conducted, distinguishing between the general practitionners, the researchers and the teaching staff. On the other hand, an in depth analysis will be conducted regarding the media available at the veterinary library. Are they suited to the practice of EBM? If not, which additional tools should be purchased ? At the end of the process, we expect to be able to adapt the content of the training sessions we offer to library users and possibly to improve the collaboration with the veterinary teaching staff. [less ▲]

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See detailEvidences palynologiques sur les relations entre le climat et la distribution géographique des flores dévoniennes et dinantiennes.
Streel, Maurice ULg

in Mémoires - Institut royal des Sciences Naturelles de Belgique (1980), XXVII(b), 261-267

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See detailEvidencia de determinantes de patogenia en las regiones Long Terminal Repeats (LTRs) del genoma del virus de la leucemia bovina (BLV)
Rodriguez, Sabrina ULg; Trono, K.; Jones, L.R.

Poster (2011, September 26)

Evidencia de determinantes de patogenia en las regiones Long Terminal Repeats (LTRs) del genoma del virus de la leucemia bovina (BLV) Sabrina M. Rodríguez1*, Karina Trono2, Leandro R. Jones3 1 Molecular ... [more ▼]

Evidencia de determinantes de patogenia en las regiones Long Terminal Repeats (LTRs) del genoma del virus de la leucemia bovina (BLV) Sabrina M. Rodríguez1*, Karina Trono2, Leandro R. Jones3 1 Molecular and Cellular Epigenetics, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), University of Liège (ULg), Belgium. 2 Instituto de Virología, CICVyA, Instituto Nacional de Tecnología Agropecuaria INTA-Castelar, CC 25 (1712), Castelar. 3 División de Biología Molecular, Estación de Fotobiología Playa Unión, CC 15, Rawson, Chubut 9103, Argentina. *E-mail: sabrina.rodriguez@ulg.ac.be El resultado de la infección por el virus de la leucemia bovina (BLV) es diverso. La mayoría de los animales infectados resultan portadores asintomáticos (AL) y cerca del 30% desarrolla una condición benigna denominada linfocitosis persistente (LP). La forma tumoral o linfosarcoma (LS) afecta a un 1-5% de los bovinos infectados. Las bases genético-moleculares del desarrollo de las distintas formas clínicas son desconocidas. Las Repeticiones Terminales Largas (Long Terminal Repeats, LTR) del genoma viral constituyen determinantes genéticos de patogenia en el caso de otros retrovirus. Sin embargo, esta posibilidad no ha sido evaluada para el BLV. Los análisis para probar la correlación entre los caracteres clínicos y genotípicos entre especies deben ser corregidos incluyendo la filogenia del grupo. De otra manera, la historia evolutiva compartida puede comprometer la independencia estadística del análisis. Sobre estas bases, el objetivo de este trabajo consistió en estudiar la influencia de las variaciones genéticas de las regiones regulatorias LTR del BLV en el desarrollo de las diferentes formas clínicas de la infección mediante métodos comparativos filogenéticos, cladísticos y probabilísticos. Con este fin, se secuenció la región 5´LTR de 40 provirus obtenidos a partir de bovinos naturalmente infectados con BLV que presentaron las diferentes formas clínicas (AL, PL, LS). Fueron identificadas siete posiciones polimórficas que mostraron una asociación aparente con la presentación clínica. Una reconstrucción de la filogenia del grupo fue realizada a partir de las secuencias de la región env obtenidas para 28 de los 40 provirus estudiados en este trabajo. En conjunto, los análisis comparativos cladísticos y probabilísticos basados en el alineamiento empírico de las secuencias y la filogenia del grupo sugieren que las posiciones 41 y 56 del 5´LTR podrían estar correlacionadas con la presentación clínica. Los análisis probabilísticos indicaron además una asociación con la patogénesis viral para las posiciones 373, 450, 494 y 505, aunque los soportes estadísticos correspondientes fueron menores en comparación con los soportes obtenidos para las posiciones 41 y 56. Estas observaciones indican que las regiones LTR del BLV podrían constituir determinantes de patogenia. [less ▲]

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See detailEviter des drames de type « Lampedusa »
Martiniello, Marco ULg

Article for general public (2013)

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See detailEviter la tour d'ivoire, éviter les allées du pouvoir
Jacquemain, Marc ULg

in Delchambre, Jean-Pierre (Ed.) Le sociologue comme médiateur ? Accords, désaccords et malentendus (2014, May)

L'article s'interroge sur la nature de l'expertise en sciences sociales. En partant de la définition de l'expertise en général par Philippe Roqueplo, on défend que la sociologie ne peut prétendre à une ... [more ▼]

L'article s'interroge sur la nature de l'expertise en sciences sociales. En partant de la définition de l'expertise en général par Philippe Roqueplo, on défend que la sociologie ne peut prétendre à une connaissance scientifique que dans le cadre des questions qu'elle pose elle-même en tant que discipline. Cela ne la dispense pas de répondre aux questions que se pose la société et, en particulier, les pouvoirs publics, mais les réponses n'ont pas le statut de réponses scientifiques. [less ▲]

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See detailEvocation d'une expérience d'enseignement: « Architecture paramétrable et architecture fractale, génération numérique des formes complexes. »
Bianchi, Romuald ULg; Defawes, Georges ULg

in Actes de SCAN'05 : Séminaire de conception architecturale numérique (2005)

cette communication relate l'élaboration d'un cours orienté vers la découverte des formes à géométrie complexe. Le contenu de ce cours, dispensé pour la 1ère fois en mai 2005, a déjà évolué. Il est apparu ... [more ▼]

cette communication relate l'élaboration d'un cours orienté vers la découverte des formes à géométrie complexe. Le contenu de ce cours, dispensé pour la 1ère fois en mai 2005, a déjà évolué. Il est apparu que les outils proposés pour explorer les formes complexes étaient également opérationnels comme outils d'assistance à l'esquisse [less ▲]

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See detailL'évocation des enfers dans la poésie latine post-virgilienne
Rochette, Bruno ULg

Scientific conference (2002)

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See detailUne évocation pythagoricienne des Enfers chez Tibulle (I, 3, 59-66)
Rochette, Bruno ULg

in Etudes Classiques (2003), 71(2), 175-180

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See detailEvoked potentials and transcranial magnetic stimulation in migraine: published data and viewpoint on their pathophysiologic significance.
Schoenen, Jean ULg; Ambrosini, Anna; Sandor, Peter S et al

in Clinical Neurophysiology (2003), 114(6), 955-72

Migraine is a disorder in which central nervous sytem dysfunction might play a pivotal role. Electroneurophysiology seems thus particularly suited to study its pathophysiology. We have extensively ... [more ▼]

Migraine is a disorder in which central nervous sytem dysfunction might play a pivotal role. Electroneurophysiology seems thus particularly suited to study its pathophysiology. We have extensively reviewed evoked potential and transcranial magnetic stimulation studies performed in migraineurs in order to identify their pathophysiologic significance. Publications available to us were completed by a Medline search. Retrieved and personal data were compared with respect to methodology and interpreted according to present knowledge on cortical information processing. Results are in part contradictory which appears to be method-, patient- and disease- related. Nonetheless, both evoked potential and transcranial magnetic stimulation studies demonstrate that the cerebral cortex, and possibly subcortical structures, are dysfunctioning interictally in both migraine with and without aura. These electrophysiologic abnormalities tend to normalise just before and during an attack and some of them seem to have a clear familial and predisposing character. Besides the studies of magnetophosphenes which have yielded contrasting results, chiefly because the method is not sufficiently reliable, most recent electrophysiologic investigations of cortical activities in migraine favour deficient habituation and decreased preactivation cortical excitability as the predominant interictal dysfunctions. We propose that the former is a consequence of the latter and that it could favour both interictal cognitive disturbances as well as a cerebral metabolic disequilibrium that may play a role in migraine pathogenesis. To summarize, electrophysiologic studies demonstrate in migraine between attacks a cortical, and possibly subcortical, dysfunction of which the hallmark is deficient habituation. [less ▲]

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See detailEvolutie van de spiereiwitturnover in vivo van vleestieren bij gebruik van anabolica
Van Eenaeme, Christian ULg; Baldwin, Paule; Lambot, Olivier et al

in Medelingen van de Vereniging van Nederlandstalige Voedingonderzoekers (1983)

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See detailDe evolutie van het vreemdelingsrecht
Carlier, Jean-Yves ULg

in Khader, Bichara; Martiniello, Marco; Rea, Andrea (Eds.) et al mmigratie en integratie anders denken. Een belgisch interuniversitair initiatief (2006)

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See detailÉvolution (1979-2008) des services d'hospitalisation en Belgique. Quels liens avec la hiérarchie urbaine ?
Trotta, Marie ULg

in Bulletin de la Société Géographique de Liège (2009), 53

This research compares the spatial pattern of services provided in hospitals just before the introduction of the moratorium stopping the growth of the hospital sector (1979) with the current situation ... [more ▼]

This research compares the spatial pattern of services provided in hospitals just before the introduction of the moratorium stopping the growth of the hospital sector (1979) with the current situation (2008) by their relationship to urban hierarchy. The method used to analyze this relationship is the application of the statistic coefficient ϒ. This work shows that this relationship is significant for the two studied periods. However, the presence of a nearby faculty of medicine appears to interfere significantly on this relationship. The study also highlights a slight tendency to the strengthening of the aforementioned relationship. Besides, it demonstrates the existence of different spatial behaviours depending on the type of service. [less ▲]

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See detailL'évolution : faits, théories et malentendus
Bouquiaux, Laurence ULg

in Comprendre l'évolution (2009)

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See detailEvolution and predictive factors of relapse in ulcerative colitis patients treated with mesalazine after a first course of corticosteroids.
Bello, C.; Belaiche, Jacques ULg; Louis, Edouard ULg et al

in Journal of Crohn's & colitis (2011), 5(3), 196-202

INTRODUCTION: Mesalazine remains the first line treatment for the induction and the maintenance of remission in mild to moderate ulcerative colitis (UC). Its efficacy as a maintenance treatment after a ... [more ▼]

INTRODUCTION: Mesalazine remains the first line treatment for the induction and the maintenance of remission in mild to moderate ulcerative colitis (UC). Its efficacy as a maintenance treatment after a first flare treated with corticosteroids has not been specifically studied. The aims of our work were to study a cohort of UC patients treated with mesalazine after a course of oral systemic corticosteroids and to identify predictive factors of relapse and of colectomy. MATERIAL AND METHOD: We studied retrospectively a cohort of 143 UC patients, who never received immunosuppressive drugs, and treated for the first time with oral corticosteroids for a flare. Among patients responding to corticosteroids, we studied the group treated by mesalazine after the flare. RESULTS: Fifty% (n=52) achieved a complete clinical remission with steroid weaning. In this group, 67% (n=35) received oral mesalazine. Seventy-five % of patients treated by mesalazine relapsed (median 29 months, range: 1-156). Fourteen % required a colectomy (median 11 months, range: 1-24). Kaplan Meier curve showed a relapse rate and a colectomy rate over one year of 26% and 11% respectively. In multivariate analysis, male gender and short duration of disease were predictive factors of the time-to-relapse. No factor was predictive of time-to-colectomy. CONCLUSION: Maintenance efficacy of mesalazine over one year after a first course of corticosteroids for a disease flare is reasonably high. The longer-term relapse rate becomes higher in male patients with a short disease duration. An immunosuppressive treatment could be discussed in case of further relapse despite improved medication-adherence. Medication-adherence should first be assessed and promoted. An immunosuppressive treatment could be discussed in case of further relapse despite improved medication-adherence. [less ▲]

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See detailEvolution annuelle de la biomasse du mysidacé Leptomysis lingvura le long d'une bande rocheuse côtière
Dauby, Patrick ULg

in Rapports et Procès-verbaux de la Commission Internationale pour l'Exploration scientifique de la Mer Méditerranée (1981), 27

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