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See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

Scientific conference (2012, October)

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See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

in Syllabus : Canadian Diabetes association : Professional Conference and Annual Meetings (2012, October)

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See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

Scientific conference (2012, March 24)

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See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

Scientific conference (2010, June)

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See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

Scientific conference (2009, October 24)

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See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

Scientific conference (2004, June)

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See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

in Meeting of the European Neuroendocrine Association, ENEA - Abstract book (2008)

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See detailFamilial isolated pituitary adenomas (FIPA) : not only acromegaly
Jaffrain-Réa, M. L.; Tamburrano, G.; Ciccarelli, A. et al

in 30 Congresso Nazionale della Socièta Italiana di Endocrinologia : Milano, 24-27 settembre 2003 (2003, September)

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See detailFamilial Isolated Pituitary Adenomas (FIPA) and the Pituitary Adenoma Predisposition due to Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene.
BECKERS, Albert ULg; Aaltonen, Lauri A.; Daly, Adrian ULg et al

in Endocrine Reviews (2013)

Pituitary adenomas are one of the most frequent intracranial tumors and occur with a prevalence of approximately 1:1000 in the developed world. Pituitary adenomas have a serious disease burden, and their ... [more ▼]

Pituitary adenomas are one of the most frequent intracranial tumors and occur with a prevalence of approximately 1:1000 in the developed world. Pituitary adenomas have a serious disease burden, and their management involves neurosurgery, biological therapies, and radiotherapy. Early diagnosis of pituitary tumors while they are smaller may help increase cure rates. Few genetic predictors of pituitary adenoma development exist. Recent years have seen two separate, complimentary advances in inherited pituitary tumor research. The clinical condition of familial isolated pituitary adenomas (FIPA) has been described, which encompasses the familial occurrence of isolated pituitary adenomas outside of the setting of syndromic conditions like multiple endocrine neoplasia type 1 and Carney complex. FIPA families comprise approximately 2% of pituitary adenomas and represent a clinical entity with homogeneous or heterogeneous pituitary adenoma types occurring within the same kindred. The aryl hydrocarbon receptor interacting protein (AIP) gene has been identified as causing a pituitary adenoma predisposition of variable penetrance that accounts for 20% of FIPA families. Germline AIP mutations have been shown to associate with the occurrence of large pituitary adenomas that occur at a young age, predominantly in children/adolescents and young adults. AIP mutations are usually associated with somatotropinomas, but prolactinomas, nonfunctioning pituitary adenomas, Cushing disease, and other infrequent clinical adenoma types can also occur. Gigantism is a particular feature of AIP mutations and occurs in more than one third of affected somatotropinoma patients. Study of pituitary adenoma patients with AIP mutations has demonstrated that these cases raise clinical challenges to successful treatment. Extensive research on the biology of AIP and new advances in mouse Aip knockout models demonstrate multiple pathways by which AIP may contribute to tumorigenesis. This review assesses the current clinical and therapeutic characteristics of more than 200 FIPA families and addresses research findings among AIP mutation-bearing patients in different populations with pituitary adenomas. [less ▲]

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See detailFamilial isolated pituitary adenomas : epidemiological, clinical and genetic studies
Ciccarelli, A.; Valdes Socin, Hernan Gonzalo ULg; Jaffrain-Rea, M. L. et al

in 12th International Congress of Endocrinology - Abstract book (2004)

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See detailFamilial Isolated pituitary adenomas and AIP gene mutations
Beckers, Albert ULg

Scientific conference (2013, November 15)

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See detailFamilial Isolated pituitary adenomas not related to the MEN-1 syndrome : A study of 27 patients
Valdes Socin, Hernan Gonzalo ULg; Betea, Daniela ULg; Stevens, V. et al

in 10th Meeting of the Belgian Endocrine Society, 2 December 2000 (2000)

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See detailFamilial Isolated pituitary adenomas not related to the MEN1 syndrome
Valdes Socin, Hernan Gonzalo ULg; Poncin, J.; Vanbelinghen, J. F. et al

in 5th European Congress of Endocrinology - Abstract book (2001)

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See detailFamilial isolated pituitary tumors : clinical and molecular studies in 80 patients
Valdes Socin, Hernan Gonzalo ULg; Jaffrain-Réa, M. L.; Tamburrano, G. et al

in The Endocrine Society's 84th Annual Meeting - Abstract book (2002)

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See detailFamilial neuronal heterotopias as cerebral palsy. An inherited disorder of brain histogenesis
Misson, Jean-Paul ULg; Verloes, Alain ULg

in European Society of Human Genetics (1991)

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See detailFamilial pituitary adenomas
vandeva, s; Vasilev, V.; Vroonen, Laurent ULg et al

in Annales d'Endocrinologie (2010), 71

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See detailFamilial Pituitary Adenomas
Auriemma, RS; Vasilev, V; Daly, Adrian ULg et al

in Endocrinologia Clinica (2012)

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See detailFamilial Pituitary Adenomas
Beckers, Albert ULg

Scientific conference (2009, June)

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See detailFamilial Pituitary Adenomas (Lettura Magistrale)
Beckers, Albert ULg

Scientific conference (2006, November 17)

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See detailFamilial Pituitary Adenomas : An overview
Vasilev, V; Daly, Adrian ULg; Beckers, Albert ULg

in Hayat, MA (Ed.) Tumors of the Central nervous system (2013)

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