Improvement of Buildings' Structural Quality by New Technologies - Outcome of the Cooperative Activities within COST C12

Book published by A.A. Balkema Publishers (2005)

Improvement of culture condition of Tetrahymena rostrata (Protozoa) for Biomass and g linolenic production.

Poster (1988, July)

Improvement of fed batch mass culture for g linolenic biosynthesis by Tetrahymena rostrata (Protozoa).

in Biotechnology Letters (1989), 11(6), 423-426

Improvement of Gc-Rich Template Amplification by Inverse Pcr

in BioTechniques (1994), 17(2), 232-4

Improvement of He ion induced SiGe layer relaxation by a thin Si:C layer

Conference (2008)

Improvement of insulin-induced glucose disposal in obese patients with NIDDM after 1-wk treatment with d-fenfluramine.

in Diabetes Care (1991), 14(4), 325-32

OBJECTIVE: To study the short-term effects of the serotoninergic anorectic drug d-fenfluramine on insulin-induced glucose disposal. RESEARCH DESIGN AND METHODS: A randomized double-blind placebo ... [more ▼]

OBJECTIVE: To study the short-term effects of the serotoninergic anorectic drug d-fenfluramine on insulin-induced glucose disposal. RESEARCH DESIGN AND METHODS: A randomized double-blind placebo-controlled crossover trial with 1-wk treatment periods (2 x 15 mg/day d-fenfluramine) was conducted. Twenty obese subjects, 10 with normal oral glucose tolerance and 10 with non-insulin-dependent diabetes mellitus (NIDDM), were all treated with a weight-maintaining diet. Euglycemic-hyperinsulinemic glucose clamps with measurement of glucose kinetics with D-[3-3H]glucose were performed at either two (patients without NIDDM, 0.05 and 0.10 U.kg-1.h-1) or three (patients with NIDDM, 0.05, 0.10, and 0.50 U.kg-1.h-1) insulin delivery rates. RESULTS: In the nondiabetic subjects, no significant changes in any metabolic or hormonal parameter were measured in the basal state or during the clamp despite a slight reduction in body weight (-1.2 +/- 0.5 kg, P less than 0.05). In the diabetic patients, no significant changes in body weight or basal plasma insulin levels were observed, but fasting blood glucose levels (8.0 +/- 0.8 vs. 9.4 +/- 1.1 mM, P less than 0.005) and plasma free fatty acid concentrations (1150 +/- 227 vs. 1640 +/- 184 microM, P less than 0.05) were significantly reduced after d-fenfluramine compared with placebo. During the clamp, insulin metabolic clearance rate (MCR) was similar after both placebo and d-fenfluramine; endogenous (hepatic) glucose production was similarly and almost completely suppressed, whereas glucose disposal was remarkably enhanced after d-fenfluramine (average increase of glucose MCR 35 +/- 12%, P less than 0.02). CONCLUSIONS: Whatever the mechanism(s) involved, a 1-wk treatment with d-fenfluramine induces better blood glucose control and improves insulin sensitivity in obese patients with NIDDM independent of significant weight reduction; this last effect is not present in obese subjects with normal oral glucose tolerance. [less ▲]

Improvement Of Lactic Cell Production

in Applied Biochemistry and Biotechnology (1998), 70-2

Improvement of lipase production by the yeast Yarrowia lipolytica

Poster (2000, March 31)

Improvement of lupin seed valorisation by the pig with the addition of alpha-galactosidase in the feed and the choice of a suited variety.

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2005), 9(4), 225-235

Three experiments were conducted to assess whether an a-galactosidase supplement improved the utilisation of lupin seeds by growing and finishing pigs and to determine the best lupin variety in presence ... [more ▼]

Three experiments were conducted to assess whether an a-galactosidase supplement improved the utilisation of lupin seeds by growing and finishing pigs and to determine the best lupin variety in presence of a-galactosidase. In experiment 1, three iso-nitrogen (iso-N) and iso-net energy (iso-NE) diets containing 15% of soybean meal (SBM diet) or 20% of lupin seeds (Lupinus albus var. Arès), with or without an a-galactosidase supplement (‘lupin’ and ‘lupin + a-gal’ diets, respectively), were ingested by 12 pigs fitted with a caecal canula, following a completely randomized experimental design. The ileal digestibility of a-galactosides tended to increase with the lupin + a-gal diet. Nitrogen retention of pigs eating the SBM diet was similar to that of those fed with the lupin + a-gal diet and higher than that observed for pigs given the lupin diet. The results suggested that a-galactosides are the main anti-nutritional factors in lupin seeds for pigs. The same diets were investigated in a production trial (experiment 2) involving 48 pigs with a live weight of between 30 and 105 kg. The fattening period was similar for the SBM and lupin + a-gal diets (107 d) and longer for the lupin diet (123 d). With the lupin diet there was a lower average daily gain (ADG, -16%) and a higher food conversion ratio (FCR, + 8%) than with the two other diets. The backfat of pigs fed with lupin-based diets contained fewer polyunsaturated fatty acids (PUFA) and had a lower w6/w3 ratio. In experiment 3, three iso-N and iso-NE diets containing different varieties of lupin (Lupinus albus cv Lublanc and Amiga; Lupinus angustifolius cv Boltensia) and an a-galactosidase supplement were investigated in 12 pigs fitted with a caecal canula, as in Exp. 1. The results showed that the digestible protein supply by the Boltensia diet was higher than in the others. However, the Boltensia variety led to a higher urinary N excretion than the Lublanc variety. The results obtained with Amiga were intermediate. Consequently, the utilisation of ingested and digested proteins was relatively high with the Lublanc diet, intermediate with the Amiga diet and low with the Boltensia diet. The results suggested that the Lublanc variety was better adapted for pig feed that contained an a-galactosidase supplement. [less ▲]

Improvement of metal dispersion in Pd/SiO2 cogelled xerogel catalysts for 1,2-dichloroethane hydrodechlorination

in Applied Catalysis B : Environmental (2004), 50

The study of the influence of synthesis operating variables (nature and concentration of complexing silane, palladium percentage, temperatures of gelling, aging and vacuum drying of xerogels, molar ratio ... [more ▼]

The study of the influence of synthesis operating variables (nature and concentration of complexing silane, palladium percentage, temperatures of gelling, aging and vacuum drying of xerogels, molar ratio between the complexing silane and palladium, molar concentration of ammonia solution, and use of tetramethylammonium hydroxide as base instead of NH3) allows improving metal dispersion in Pd/SiO2 cogelled xerogel catalysts. The use of 3-(2-aminoethylamino)propyltrimethoxysilane (EDAS) or 3-(2-aminoethylamino)propyltriethoxysilane (EDAES) to complex palladium in an ethanolic solution containing tetraethoxy si lane (TEOS) and an ammonia solution of 0.54 mol/l allows obtaining a Pd/SiO2 xerogel catalyst with a mean metal particle diameter of 2.4 nm located inside silica particles. Indeed, complexes Pd(EDA(E)S)(x)(n+) induce a nucleation mechanism because of their higher reactivity compared to the network-reagent (TEOS). Although metal particles are located inside the silica particles, their complete accessibility, via the micropore network, has been shown. 1,2-dichloroethane hydrodechlorination over Pd/SiO2 catalysts mainly produces ethane and the specific hydrodechlorination rate per gram of palladium increases proportionally with palladium dispersion. Hydrodechlorination over Pd/SiO2 cogelled xerogel catalysts is a structure insensitive reaction with regard to the ensemble size concept. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]