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See detailLe feuilleton de l'expertise (contradictoire) en matière pénale
Jacobs, Ann ULg

in Information et document juridqiques (2000), (4), 1-2

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See detailLes Feuillets de Liège de Fernand Desonay (1934-1935)
Droixhe, Daniel ULg

in Bon-A-Tirer : Revue Littéraire en Ligne (2010), 138

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See detail"Les Feux de la rampe" de Charlie Chaplin
Tomasovic, Dick ULg

Conference given outside the academic context (2013)

Présentation du contexte de création et de production du film "Les Feux de la rampe"

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See detailLa féverole en alimentation animale
Beckers, Yves ULg

Scientific conference (2011, May 05)

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See detailA few considerations on photometric databases.
Heck, A.; Manfroid, Jean ULg

in European Southern Observatory Astrophysics Symposia (1988)

Problems related to the homogenization of photometric data are commented, in the perspective of existing and potential photometric data banks. The need for keeping individual photometric measurements of ... [more ▼]

Problems related to the homogenization of photometric data are commented, in the perspective of existing and potential photometric data banks. The need for keeping individual photometric measurements of programme and standard objects accessible is stressed. A complete description of each instrumental system should also be archived. [less ▲]

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See detailA FEW GOOD REASONS TO CONSIDER A BEAM FINITE ELEMENT FORMULATION ON THE LIE GROUP SE(3)
Sonneville, Valentin ULg; Bruls, Olivier ULg

in Proceedings of the ASME 2013 International Design Engineering Technical Conference & Computers and Information in Engineering Conference IDETC/CIE 2013 (2013, August)

Based on an original interpolation method we develop a beam finite element formulation on the Lie group SE(3) which relies on a mathematically rigorous framework and provides compact and generic notations ... [more ▼]

Based on an original interpolation method we develop a beam finite element formulation on the Lie group SE(3) which relies on a mathematically rigorous framework and provides compact and generic notations. We work out the beam kinematics in the SE(3) context, the beam deformation measure and obtain the expression of the internal forces using the virtual work principle. The proposed formulation exhibits important features from both the theoretical and numerical points of view. The approach leads to a natural coupling of position and rotation variables and thus differs from classical Timoshenko/Cosserat formulations. We highlight several important properties such as a constant deformation measure over the element, an invariant tangent stiffness matrix under of rigid motions or the absence of shear locking. [less ▲]

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See detailA few methods of evaluating product temperature during thin bed drying.
Bera, François ULg; Deladriere, J. L.; Renauld, H. et al

in Bruin S. (Ed.) Process Technology Proceedings: Preconcentration and drying of food materials. (1988)

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See detailA few notes on my career as an astrophysicist
Swings, Polydore ULg

in Annual Review of Astronomy and Astrophysics (1979), 17

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See detailA few thoughts about representative actions
Sibony, Anne-Lise ULg

in Gheur, Charles; Petit, Nicolas (Eds.) Alternative enforcement techniques in EC Competition law: Settlement, commitments and other novel instruments (2009)

These brief remarks (originally made as a panel member commenting on other speaker's views) touch on two elementary questions regarding representative actions envisaged in the Commission's White Paper on ... [more ▼]

These brief remarks (originally made as a panel member commenting on other speaker's views) touch on two elementary questions regarding representative actions envisaged in the Commission's White Paper on Damages Actions for Breach of the EC antitrust rules. The first question adressed is "who will represent whom?". On this aspect, an analogy is drawn with the proposed directive on access to justice in environmental law matters. The second issue concerns conflicting preferences of consumers and corporate defendants regarding publicity of proceedings in which consumer's claims for damages are adjudicated. [less ▲]

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See detailA few thoughts on dyslexia
Garcet, Serge ULg

in Ericson, Britta (Ed.) Reading and writing difficulties, a problem? (1999)

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See detailA few toughts on dyslexia
Garcet, Serge ULg

Report (1998)

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See detailFewer pre-emptive renal transplantations and more rejections in immigrant children compared to native Dutch and Belgian children.
Tromp, Wilma F.; Cransberg, Karlien; van der Lee, Johanna H. et al

in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2012), 27(6), 2588-93

BACKGROUND: In the Netherlands and Belgium, an increasing number of children who have end-stage renal disease (ESRD) are of non-Western origin. We analysed renal transplantation practices and outcome for ... [more ▼]

BACKGROUND: In the Netherlands and Belgium, an increasing number of children who have end-stage renal disease (ESRD) are of non-Western origin. We analysed renal transplantation practices and outcome for immigrant ESRD children as compared to native children in both countries. METHODS: All Dutch and Belgian children aged <19 years who received their first renal transplantation between 1 September 2007 and 1 January 2011 were included. Therapy characteristics and outcomes were registered prospectively on a 3-monthly basis. Immigrants were defined as children of whom one or both parents had been born outside Western European countries. Multivariable Cox regression analysis was used to quantify the hazard ratio for acute rejection. RESULTS: One hundred and nineteen first renal transplant recipients were included, of which 41 (34%) were immigrants. Median [range] follow-up time of transplantation was 18 [2-28] months. Compared to native children, immigrants had pre-emptive transplantations (15 versus 32%, P = 0.040) and transplantations with a kidney from a living donor less often (24 versus 59%, P < 0.001). Survival analysis in 96 children with at least 3 months of follow-up showed an increased risk for acute rejection in immigrants adjusted for donor source, duration of dialysis and number of HLA mismatches on the DR locus [hazard ratio (95% confidence interval) 2.5 (1.1-5.9)]. CONCLUSIONS: Immigrant children receive fewer pre-emptive and living donor transplantations compared to native children. After transplantation, immigrant children are at higher risk for acute rejection irrespective of the mode of transplantation. [less ▲]

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See detailFe–Ti–V–P ore deposits associated with Proterozoic massif-type anorthosites and related rocks
Charlier, Bernard ULg; Namur, Olivier; Bolle, Olivier ULg et al

in Earth-Science Reviews (2015), 141(0), 56-81

Magmatic rocks containing economic concentrations of iron, titanium, vanadium and phosphorous are commonly associated with massif-type anorthosites and related rocks. This rock association is part of the ... [more ▼]

Magmatic rocks containing economic concentrations of iron, titanium, vanadium and phosphorous are commonly associated with massif-type anorthosites and related rocks. This rock association is part of the anorthosite–mangerite–charnockite–(rapakivi-)granite suites that are restricted to the Proterozoic. Understanding the geochemistry and emplacement mechanisms of ilmenite, magnetite and apatite ore deposits is crucial for exploration, efficient mining operations and ore processing. This review discusses the controlling factors on the grade of an ore, its mineralogy, and its major and trace element distribution. We present petrogenetic models of currently mined deposits (Lac Tio, Tellnes, Damiao) and discuss the characteristics of minor ore bodies from anorthosite provinces worldwide (Grenville, North China Craton, East European Craton, Rogaland, Laramie). Models of formation of anorthosite and related rocks are presented, as well as the nature of the possible parental magmas of the suite. A mineralogical classification of Fe–Ti ores is proposed: (1) Gabbro-noritic ilmenite ore ± apatite ± magnetite; (2) Ti-magnetite-dominated ore; (3) Nelsonite (Fe–Ti oxides + apatite); and (4) Rutile-ilmenite ore. The stability of ilmenite and magnetite is then critically reviewed and the influence of various factors, particularly oxygen fugacity and crystallization pressure, is examined. We discuss liquidus compositions of Fe–Ti oxides and the behavior of important trace elements such as Cr and V, both of which are sensitive to fO2 variations. Post-cumulus evolution of both oxides can occur due to re-equilibration with trapped liquid, re-equilibration with ferromagnesian silicates, exsolution, oxidation, reaction between ilmenite and magnetite, and metamorphic overprinting. These various processes are described and their effects on the oxide geochemistry are emphasized. Several potential ore-forming processes have been invoked and can explain the formation of huge concentration of ilmenite, ± magnetite, ± apatite. Fractional crystallization can be combined with crystal sorting and plagioclase buoyancy to produce relative enrichment of dense ore minerals. Silicate liquid immiscibility can segregate conjugate Si-rich and Fe-rich melts, the latter being enriched in Fe–Ti–P. Magma mixing can produce hybrid magmas located in a single-phase field of the phase diagram and precipitate a pure ilmenite cumulate. Alternative processes are also described, such as ejection of Fe–Ti-enriched residual melts by filter-pressing and compaction, solid-state remobilization of ilmenite in veins, and hydrothermal transport of Fe and Ti from the host anorthosite followed by concentration in veins and lenticular ore bodies. The magnetic properties of Fe–Ti ore deposits present contrasting signatures, depending on whether the natural remanent magnetization is dominated by hemo-ilmenite or multi-domain magnetite. Micro- and macro-scale deformation features of ore rocks are intimately correlated with magma emplacement, and with ballooning of the anorthosite diapir associated with gravitational sagging of dense ore bodies. Exploration perspectives show that oxide-apatite gabbronorites are interesting targets because ilmenite in these rocks is poorer in Cr and Mg, and because the Ti-resource may be combined with apatite and vanadiferous magnetite. [less ▲]

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See detailffects of oligofructose on glucose and lipid metabolism in patients with nonalcoholic steatohepatitis : results of a pilot study
Daubioul, C. A.; Horsmans, Y.; Lambert, Philippe ULg et al

in European Journal of Clinical Nutrition (2005), 59

Objective: In experimental animals, recent results suggest that the addition of inulin-type fructans such as oligofructose (OFS) in the diet decreases triacylglycerol accumulation in the liver tissue ... [more ▼]

Objective: In experimental animals, recent results suggest that the addition of inulin-type fructans such as oligofructose (OFS) in the diet decreases triacylglycerol accumulation in the liver tissue. Therefore, we have investigated the effect of daily ingestion of OFS in seven patients with nonalcoholic steatohepatitis (NASH), confirmed by liver biopsies. Design: They received 16 g/day OFS or maltodextrine (placebo) for 8 weeks in a randomized double-blind crossover design. Energy intake, body composition, liver steatosis and blood parameters were analysed after 4 and 8 weeks of dietary supplementation. Results: Compared to placebo, OFS decreased significantly serum aminotransferases, aspartate aminotransferase after 8 weeks, and insulin level after 4 weeks, but this could not be related to significant effect on plasma lipids. Conclusion: This pilot study supports the putative interest of OFS in the management of liver diseases associated with abnormal lipid accumulation in humans. [less ▲]

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See detailFgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development.
Larbuisson, Arnaud ULg; Dalcq, Julia ULg; Martial, Joseph ULg et al

in Differentiation; research in biological diversity (2013), 86

Cranial cartilage derives mainly from cranial neural crest cells and its formation requires fibroblast growth factor (Fgf) signaling for early differentiation and survival of developing chondrocytes as ... [more ▼]

Cranial cartilage derives mainly from cranial neural crest cells and its formation requires fibroblast growth factor (Fgf) signaling for early differentiation and survival of developing chondrocytes as well as patterning of the endodermal pouches. Here, we investigate the role of Fgf receptors in chondrocyte maturation at later stages, beyond 24hpf. Using inducible expression of a dominant-negative Fgf receptor, we show that Fgf signaling is required around 30hpf for correct cartilage formation. The receptor genes fgfr1a and fgr2 are expressed in pharyngeal endodermal pouches after 24hpf or 26hpf, respectively. Depletion of any of these two receptors by microinjection of antisense morpholinos results in severe defects in cartilage formation at 4dpf and a decrease in expression of the late chondrocyte markers barx1 and runx2b. Although endodermal pouches are correctly formed and patterned, receptor knock down leads to decreased expression of runx3, egr1 and sox9b in this tissue, while expression of fsta, coding for a secreted BMP/Tgfss inhibitor, is clearly increased. Rescue experiments revealed that each Fgfr1a or Fgfr2 receptor is able to compensate for the loss of the other. Thus, we show that minimal amounts of Fgfr1a or Fgfr2 are required to initiate a regulatory cascade in pharyngeal endoderm reducing expression of fsta, thereby allowing correct BMP signaling to the maturing chondrocytes of the head cartilage. [less ▲]

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See detailFGF-23 et Klotho: une avancée dans le métabolisme du phosphore
CAVALIER, Etienne ULg

Scientific conference (2011, February 10)

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See detailFgf-3 and Fgf-4 Elicit Distinct Oncogenic Properties in Mouse Mammary Myoepithelial Cells
Hajitou, Amin; Baramova, Eugénia; Bajou, Khalid ULg et al

in Oncogene (1998), 17(16), 2059-71

Fibroblast Growth Factors 3 (FGF-3) and 4 (FGF-4) were compared for the effects they each exert on EF43 mouse cells. This non-transformed mammary cell line appears to be myoepithelial mainly because it ... [more ▼]

Fibroblast Growth Factors 3 (FGF-3) and 4 (FGF-4) were compared for the effects they each exert on EF43 mouse cells. This non-transformed mammary cell line appears to be myoepithelial mainly because it expresses alpha-smooth muscle actin. The EF43 cells were infected with similar vectors that carry either the short fgf-3 sequence (the product of which goes into the secretory pathway), fgf-4 or the selection gene only as control. In syngeneic animals, EF43.fgf-3 cells were tumorigenic only when orthotopically implanted whereas EF43.fgf-4 cells invariably gave rise to aggressive tumors. However, both tumor types were metastatic as evidenced by the blue micrometastases observed when the implanted cells expressed lacZ. In vitro, the FGF-3 producing cells were strongly invasive in matrigel coated chambers whereas the EF43.fgf-4 cells only were invasive in type I-collagen gels. Interestingly, FGF-3 production greatly stimulated the synthesis of pro-MMP-9 (Matrix Metalloprotease-9) and, to a lesser extent, that of pro-MMP-2. FGF-3 also up-regulated the production of plasminogen activators. In contrast, FGF-4 had no effect on these secretions and the medium conditioned by the EF43.fgf-4 cells displayed the largest plasminogen activator-inhibitor activity. These results show that FGF-3 and FGF-4 have distinct mechanisms of action on myoepithelial cells. [less ▲]

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See detailFGF23 and Klotho: an emerging role in phosphate metabolism
CAVALIER, Etienne ULg

Conference (2011, April)

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See detailFhit regulates EMT targets through an EGFR/Src/ERK/Slug signaling axis in human bronchial cells.
Joannes, Audrey; Grelet, Simon; Duca, Laurent et al

in Molecular Cancer Research (2014), 12(5), 775-83

In many cancers, including lung carcinomas, Fragile histidine triad (Fhit) is frequently decreased or lost. Fhit status has recently been shown to be associated with elevated in vitro and in vivo ... [more ▼]

In many cancers, including lung carcinomas, Fragile histidine triad (Fhit) is frequently decreased or lost. Fhit status has recently been shown to be associated with elevated in vitro and in vivo invasiveness in lung cancer. Tumor cell invasion is facilitated by epithelial-mesenchymal transition (EMT), a process by which tumor cells lose their epithelial features to acquire a mesenchymal cell-like phenotype. In this study, the mechanism underlying Fhit-regulated EMT was deciphered. Using Slug knockdown, pharmacologic inhibitors PD98059, PP1, and gefitinib as well as an anti-EGFR antibody, it was demonstrated that Fhit silencing in bronchial cells induced overexpression of two primary EMT-associated targets, MMP-9 and vimentin, to regulate cell invasion dependent on an EGFR/Src/ERK/Slug signaling pathway. Moreover, ectopic expression of Fhit in Fhit-deficient lung cancer cells downregulated this pathway. Finally, an inverse correlation was observed between Fhit and phospho-EGFR levels in a cohort of human squamous cell lung carcinoma specimens. These results demonstrate a Fhit-dependent mechanism in the control of EMT-regulated EGFR signaling. IMPLICATIONS: This study adds new insight into the regulatory mechanism of EMT, a process known to increase resistance to conventional and targeted therapies in lung cancer. [less ▲]

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See detailFhit regulates invasion of lung tumor cells
Joannes, A.; Bonnomet, A.; Bindels, S. et al

in Oncogene (2010), 29(8), 1203-13

In many types of cancers, the fragile histidine triad (Fhit) gene is frequently targeted by genomic alterations leading to a decrease or loss of gene and protein expression. Fhit has been described as a ... [more ▼]

In many types of cancers, the fragile histidine triad (Fhit) gene is frequently targeted by genomic alterations leading to a decrease or loss of gene and protein expression. Fhit has been described as a tumor suppressor gene because of its ability to induce apoptosis and to inhibit proliferation of tumor cells. Moreover, several studies have shown a correlation between the lack of Fhit expression and tumor aggressiveness, thus suggesting that Fhit could be involved in tumor progression. In this study, we explored the potential role of Fhit during tumor cell invasion. We first showed that a low Fhit expression is associated with in vivo and in vitro invasiveness of tumor cells. Then, we showed that Fhit overexpression in Fhit-negative highly invasive NCI-H1299 cells by transfection of Fhit cDNA and Fhit inhibition in Fhit-positive poorly invasive HBE4-E6/E7 cells by transfection of Fhit small interfering RNA induce, respectively, a decrease and an increase in migratory/invasive capacities. These changes in cell behavior were associated with a reorganization of tight and adherens junction molecules and a regulation of matrix metalloproteinase and vimentin expression. These results show that Fhit controls the invasive phenotype of lung tumor cells by regulating the expression of genes associated with epithelial–mesenchymal transition. [less ▲]

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