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See detailEvaluation of the impact of 6-month training by whole body vibration on the risk of falls among nursing home residents, observed over a 12-month period: a single blind, randomized controlled trial.
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Maquet, Didier ULg et al

in Aging Clinical & Experimental Research (2014), 26(4), 369-376

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement ... [more ▼]

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement of motor capacity were observed. OBJECTIVE: The objective of the present study was to evaluate the impact of 6-month training by WBV on functional and motor abilities among nursing home residents observed over a 12-month period. METHODS: Patients were randomized into two groups: the WBV group which received three training sessions every week composed of five series of 15 s of vibration at 30 Hz intensity for a period of 6 months and a control group with normal daily life. The impact of this training on the risk of falls was assessed blindly after 6 and 12 months by the Tinetti Test, the "Timed Up and Go" test and a quantitative evaluation of a 10-s walk performed with a tri-axial accelerometer. The occurrence of falls was also observed. RESULTS: 62 elderly healthy volunteers, (47 women and 15 men, mean age 83.2 +/- 7.9 years) were included in this study. There was no significant difference between the two groups regarding the Tinetti test (p = 0.75), the "Timed Up and Go" test (p = 0.19) and the Locometrix(R) test, except for the step length, measured by dual task (p < 0.01). No significant inter-group difference in the frequency of falls was observed during the 12 months of research. A total of 42 falls were recorded during the first 6 months of experimentation: 24 falls in the treated group and 18 in the control group (p = 0.60). During the next 6 months, 19 falls occurred: 8 falls in the treated group and 11 in the control group (p = 0.52). CONCLUSION: This study failed to establish the effectiveness of low doses of WBV, under the conditions used in our study, on functional and motor abilities of institutionalized elderly patients. However, given the positive results of other studies, further investigations, with modified therapeutic protocols, seem necessary to clarify the effects of WBV in the elderly. [less ▲]

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See detailEvaluation of the impact of a 6-month training by whole body vibration on the risk of falls among nursing home residents
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Demonceau, Marie ULg et al

in Osteoporosis International (2013, April), 24(Suppl.1), 246-247

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See detailEvaluation of the impact of Triclosan on the functioning of the thyroid system in Cyprinodon variegatus L., 1803.
Rahmouni, Chahrazed; Benichou, Farida; Klaren, PHM et al

Poster (2014, December)

Triclosan (5-chloro-2-[2, 4-dichlorophenoxy] phenol) is an antimicrobial widely used in various industrial products such as textiles, cosmetics and body care products. It is often detected in aquatic ... [more ▼]

Triclosan (5-chloro-2-[2, 4-dichlorophenoxy] phenol) is an antimicrobial widely used in various industrial products such as textiles, cosmetics and body care products. It is often detected in aquatic environments. The presence of the main biotransformation product, methyl TCS, indicates that this compound is not only degraded, but also persistent and accumulates in aquatic organisms. In this study, the effects of TCS on the thyroid system during embryonic and larval stages in Cyprinodon variegatus were evaluated. In particular, whole body thyroid hormone levels and the activity of deiodinases, enzymes involved in the activation of the thyroid prohormone T4, were measured. Couples of three females and two males were placed in breeding chambers designed for this experiment from which 3832 eggs were obtained by reproduction in the laboratory. Eggs were collected and maintained in seawater. Embryos were selected under a dissection microscope, randomly assigned to each of five treatment groups: Control, DMSO control (vehicle), 20 μg/L TCS, 50 μg/L TCS and 100 μg/L TCS and placed in incubation dishes (50 per dish) at 25°C. On day 6, embryos hatched and larvae were transferred to 1L dishes. The larvae were fed on artemia and on flaked fish food till day 15 post hatching when the fish were analyzed. The fertilization and survival rate, as well as the larval dry weight did not vary significantly between individuals exposed to 20, 50 and 100 μg/L TCS. T3 and T4 concentrations increased significantly in larvae exposed to 50 and 100 μg/L TCS. The study of the activity of enzymes involved in the deiodination of thyroid hormones (ORD) represents a new aspect in the study of endocrine disruption in C. variegatus. Unfortunately, we were not able to detect a net enzymatic T4 deiodination activity, most likely due to the very small amounts of protein and low specific enzyme activity in brain homogenates, carcass and liver. [less ▲]

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See detailEvaluation of the influence of age on pulmonary arterial pressure by use of right ventricular catheterization, pulsed-wave Doppler echocardiography, and pulsed-wave tissue Doppler imaging in healthy Beagles.
Mercier, Elise ULg; Mathieu, Myrielle; Sandersen, Charlotte ULg et al

in American Journal of Veterinary Research (2010), 71(8), 891-7

OBJECTIVE: To assess the influence of age on pulmonary hemodynamics and hemorheological properties in healthy dogs. ANIMALS: 14 healthy Beagles. PROCEDURES: Dogs were placed in 2 age groups as follows ... [more ▼]

OBJECTIVE: To assess the influence of age on pulmonary hemodynamics and hemorheological properties in healthy dogs. ANIMALS: 14 healthy Beagles. PROCEDURES: Dogs were placed in 2 age groups as follows: young dogs (<or= 5 years old; n = 8) and old dogs (>or= 8 years old; 6). Hematologic characteristics, plasma total protein and fibrinogen concentrations, and blood viscosity were measured. Systolic time intervals of pulmonary blood flow were recorded by pulsed-wave Doppler echocardiography. Early (E') and late (A') diastolic myocardial velocities, isovolumic contraction velocity, and systolic myocardial velocity of the free tricuspid annulus were recorded by pulsed-wave tissue Doppler imaging (TDI). Dogs were anesthetized and pulmonary arterial pressures (PAP) and cardiac output were recorded with a pediatric thermodilution Swan-Ganz catheter. RESULTS: Hemorheological measurements were not different between the 2 groups. Systolic, mean, and diastolic PAP were higher in old dogs, compared with values in young dogs; this difference was attributed to a high pulmonary vascular resistance and low arterial compliance in old dogs. Systolic time intervals of pulmonary blood flow stayed unchanged. The A' wave of the free tricuspid annulus was increased in old, compared with that young dogs, and the E':A' ratio was decreased. Pulmonary vascular resistance was inversely correlated with compliance. CONCLUSIONS AND CLINICAL RELEVANCE: The age of dogs should be taken into account when interpreting pulmonary hemodynamic results and TDI variables of right ventricular diastolic function. [less ▲]

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See detailEvaluation of the IOS as a non-invasive method for pulmonary function testing in horses
Van Erck, Emmanuelle; Art, Tatiana ULg; Lekeux, Pierre ULg

in Proceedings of the 36th British Equine Veterinary Association Congress (1997)

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See detailEvaluation of the lipid-drug association constant in model membranes: A monolayer approach
Goormaghtigh, E.; Brasseur, Robert ULg; Vanderbranden, M. et al

in Bioelectrochemistry and Bioenergetics (Lausanne, Switzerland) (1982), 9(4), 489-498

A general procedure of evaluation of the lipid-drug association constant in monolayer is presented. Lipids are spread at the air-water interface and the drugs injected into the aqueous subphase ... [more ▼]

A general procedure of evaluation of the lipid-drug association constant in monolayer is presented. Lipids are spread at the air-water interface and the drugs injected into the aqueous subphase. Association constant potential and predictions from the Gouy-Chapman theory. Several procedures of calculation are described. [less ▲]

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See detailEvaluation of the load bearing capacity of thin-walled steel members for long span composite floors
Rossi, Barbara ULg; Jaspart, Jean-Pierre ULg

in International Colloquium on Stability and Ductility of Steel Structures : SDSS2006, Lisbon 6-8 September 2006 (2006)

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See detailEvaluation of the long-term barrier effect of commercial resorbable guided tissue regenerative membranes : an in vitro study using human gingival fibroblasts
Grenade, Charlotte ULg; Borget, Pascal; Moniotte, Nicolas et al

Poster (2009)

Introduction The first part of the study devoted to guided tissue regenerative membranes was focused on a better understanding of the physicochemical and mechanical properties of commercial materials. The ... [more ▼]

Introduction The first part of the study devoted to guided tissue regenerative membranes was focused on a better understanding of the physicochemical and mechanical properties of commercial materials. The second objective of our study was to develop an in vitro device able to measure the long-term barrier effect of resorbable membranes. After the development of this new device, experiments were realized to characterize the long-term behaviour of commercially membranes with human gingival fibroblasts (HGF). Materials and methods The use of human gingival fibroblastic cells was chosen to get closer to biological conditions. Some gingival explants were removed in young and non-smoking healthy patients. From these explants, fibroblastic cells were isolated and cultivated. These cells will be able to be used between the third and the sixth passage. Resorbable membranes were chosen because they don’t require a second surgical operation. There are made of polyesters or collagen. A system based on inserts was developed in order to follow the degradation of membranes and the migration of cells across the material. The membrane was cut into 8 mm diameter punches and set in the bottom of the system. Once the whole was put together, it is laced into a 12 wells plate culture. First, the plates were put in an incubator at 37°C, during times ranging from 24 hours to several months. The barrier effect was then measured to reflect the gradual increase of permeability of each membrane. For this purpose, HGF were seeded on the different samples. The top of the bottle and the bottom of the well were then filled with culture medium. Non degradable synthetic Bioflex membranes were chosen as control samples which don't let pass cells (porosity : 0,4 µm). After 48 hours of incubation in the presence of cells, pictures of cells on membranes and in the bottom of wells were taken with an optic microscope. Viability tests (MTS) were then realized on membranes to evaluate cells proliferation and in the bottom of wells to measure barrier effect. Finally, the morphology of cells on selected membranes was characterized by Scanning Electron Microscopy. Conclusion Proliferation results correspond to data published by several authors. Furthermore, the barrier effect times found in the present study are similar to barrier effect times demonstrated in in vivo studies and announced by manufacturers. In conclusion, the finalized system is adapted to the analysis of long-term barrier effect of commercial GTR membranes. This system will be tested with synthetic bioresorbable membranes made of copolymers. [less ▲]

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See detailEvaluation of the MAR and WRF regional climate models over Svalbard
Lang, Charlotte ULg; Fettweis, Xavier ULg; Doutreloup, Sébastien ULg et al

Conference (2012, June 01)

It is well known that high latitude zones are very sensitive to climate change. As a result of global warming, ice sheet melting has increased which in turn has an influence on climate through ... [more ▼]

It is well known that high latitude zones are very sensitive to climate change. As a result of global warming, ice sheet melting has increased which in turn has an influence on climate through modifications of the thermohaline circulation, feedback of ice albedo, sea level rise... Svalbard is an archipelago between 74 and 81°lat N and 60 percent of its area (62 248 km2) is covered with glaciers and ice sheets. The impact of global warming on the Svalbard cryosphere can be estimated with climate models. However, we need to use regional climate models as they offer the possibility of a higher resolution than general circulation models. We have ran two regional climate models (MAR and WRF) at a 10-kilometre resolution between 2006 and 2010 over Svalbard and compared their simulated climate to near surface measurements at several weather stations through the archipelago in order to determine which one of them could best represent the Svalbard climate. [less ▲]

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See detailEvaluation of the mechanical integrity of a concrete surface by means of combined destructive methods
Courard, Luc ULg; Bissonnette, Benoît; Garbacz, Andrzej et al

in Grantham, Michael; Basheer, Muhammed; Magee, Bryan (Eds.) et al Proceedings of Concrete Solutions (2014)

As a tight bond between the repair and the old concrete is required, the soundness of the prepared surface has to be carefully assessed. This paper presents the results of an investigation intended to ... [more ▼]

As a tight bond between the repair and the old concrete is required, the soundness of the prepared surface has to be carefully assessed. This paper presents the results of an investigation intended to assess and compare quantitatively different test methods, namely the Schmidt rebound hammer, the pull-out test and the pull-off test, to evaluate superficial mechanical integrity of a substrate after concrete removal operations. Although it does not yield a precise evaluation of compressive strength, the Schmidt rebound hammer test is recognized as a useful tool for performing quick surveys to assess concrete uniformity. The pull-off test is very well correlated with the splitting-tensile test, but it is not suited for vertical and overhead surfaces. The Capo pull-out test has limited interest for surface preparation, as it is applicable to flat surfaces only. Conversely, the accelerated pull-out test showed interesting potential as a simple and relatively rapid means for assessing the mechanical integrity of a concrete surface prior to repair for any type of concrete surface. It appears from the results generated in this study that the combination Schmidt hammer / pull-off test could fill the needs for the evaluation of horizontal surfaces after concrete removal, while the combination Schmidt hammer / accelerated pull-out test could be used effectively on vertical and overhead surfaces. [less ▲]

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See detailEvaluation of the mechanical properties of plasma-sprayed coating by nanoindentation technology
Guo, Weichao; Rauchs, Gast; Papeleux, Luc ULg et al

in Mechanics & Industry (2012), 13(3), 151-162

In this paper, the mechanical properties of plasma-sprayed coatings are evaluated using the technology of nanoindentation. According to the indentation curve (load versus indenter’s displacement), which ... [more ▼]

In this paper, the mechanical properties of plasma-sprayed coatings are evaluated using the technology of nanoindentation. According to the indentation curve (load versus indenter’s displacement), which is recorded in an indentation experiment, the mechanical behaviour of the plasma-sprayed coating is investigated via inverse analysis using numerical optimization algorithms. The tip rounding of imperfect indenters is investigated in parameter identification. Subsequently, the hardness on the top surface and on the vertical cross section of the plasma-sprayed coating are investigated. The results show that the hardness on the top surface of the coating depends on the indentation depth. Moreover, the results show that the hardness on the cross section of the coating is significantly affected by the substrate if the indentation impression is too close to the coating-substrate interface. [less ▲]

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See detailEvaluation of the metabolic safety of aripiprazole
De Hert, M.; Van Eyck, D.; Hanssens, L. et al

in Schizophrenia Research (2006, January), 81(Suppl. S), 133

Detailed reference viewed: 15 (4 ULg)