Hyperparathyroidism in multiple endocrine neoplasia type 1 : Surgical trends and results : a 256-patient series from the genem study group

in World Journal of Surgery (2001), 25(7), 886-890

Hyperpaysages - Sensibiliser à l'aménagement du territoire par les nouvelles technologies

in Point sur la Recherche en Education (Le) (2002)

Hyperplasia of rat arteries smooth muscle cells associated with development and reversal of renal hypertension.

in Clinical Science (1980), 59(suppl 6), 335-338

1. Renal hypertension produces a marked and rapidly detectable hypertrophy of the rat aorta, due to smooth muscle cell hyperplasia and connective tissue deposition. 2. As we described previously for ... [more ▼]

1. Renal hypertension produces a marked and rapidly detectable hypertrophy of the rat aorta, due to smooth muscle cell hyperplasia and connective tissue deposition. 2. As we described previously for collagen synthesis, cell hyperplasia is a very early event which reaches a maximum at a time when the blood pressure is far from its highest level, and thereafter progressively decreases. 3. Reserpine prevents the vascular wall changes on the arterial as well as the venous side of the circulation. On the other hand, captopril although effective in preventing the blood pressure rise does not suppress the hyperplastic response. 4. The arterial hypertensive disease appears to be reversible, when renal ischaemia is corrected. The smooth muscle cell hyperplasia is, however, only partly and slowly reversible. 5. These data suggest that blood pressure is not the only determinant of the vascular wall response, and that the effect of a drug on the blood pressure does nt necessarily predict the vascular wall response. [less ▲]

Hyperplasia-adenoma sequence in pituitary tumorigenesis related to aryl hydrocarbon receptor interacting protein gene mutation.

in Endocrine-Related Cancer (2011)

Mutations of the aryl hydrocarbon receptor interacting protein (AIP) gene are associated with pituitary adenomas that usually occur as familial isolated pituitary adenomas (FIPA). Detailed pathological ... [more ▼]

Mutations of the aryl hydrocarbon receptor interacting protein (AIP) gene are associated with pituitary adenomas that usually occur as familial isolated pituitary adenomas (FIPA). Detailed pathological and tumor genetic data on AIP mutation-related pituitary adenomas are scarce. Non-identical twin females presented as adolescents to the emergency department with severe progressive headaches caused by large pituitary macroadenomas requiring emergency neurosurgery; one patient had incipient pituitary apoplexy. Post-surgically the patients were found to have silent somatotrope adenomas on pathological examination. Furthermore, the light microscopic, immunohistochemical and electron microscopic studies demonstrated tumors of virtually identical characteristics. The adenomas were accompanied by multiple areas of pituitary hyperplasia, which stained positively for growth hormone, indicating somatotrope hyperplasia. Genetic analyses of the FIPA kindred revealed a novel E216X mutation of the AIP gene, which was present in both affected patients and the unaffected father. Molecular analysis of surgical specimens revealed loss of heterozygosity (LOH) in the adenoma, but showed that LOH was not present in the hyperplasic pituitary tissue from either patient. AIP immunostaining confirmed normal staining in the hyperplastic tissue and decreased staining in the adenoma in the tumors from both patients. These results demonstrate that patients with AIP germline mutation can present with clinically silent somatotroph pituitary adenomas. The finding of somatotrope hyperplasia unaccompanied by AIP LOH, suggests that LOH at the AIP locus may be a late event in the progression from hyperplastic to adenomatous tissue. [less ▲]

Hyperplasie bénigne de la prostate

in La revue de Médecine générale (1999), (161), 120-129

Les hyperprolactinémies adénomateuses - Actualités

Scientific conference (2002, November)

L'hypersensibilité à l'électricité: une approche multidisciplinaire pour un problème multifactoriel. Revue de la littérature

in European Review of Applied Psychology = Revue Européenne de Psychologie Appliquée (2005), 55

L’hypersensibilité à l’électricité (HE) est un syndrome essentiellement défini par le patient lui-même, lequel présente des plaintes qu’il attribue à l’usage ou à la proximité d’appareils ou d’équipements ... [more ▼]

L’hypersensibilité à l’électricité (HE) est un syndrome essentiellement défini par le patient lui-même, lequel présente des plaintes qu’il attribue à l’usage ou à la proximité d’appareils ou d’équipements émettant des champs électriques (CE), magnétiques (CM) ou électromagnétiques (CEM). La plupart des recherches, scandinaves, indiquent des plaintes dermatologiques chez des travailleurs sur écran mais de plus en plus de personnes se plaignent d’un syndrome plus général de type neurasthénique qui s’étend à d’autres sources de rayonnements nonionisants, lignes à haute tension et systèmes de mobilophonie. Ce terme n’implique pas de relation démontrée entre l’exposition aux champs électromagnétiques et les symptômes rapportés, comme l’indiquent les études de provocation. L’origine de l’hypersensibilité à l’électricité serait davantage multifactorielle et invite à la prise en considération multidisciplinaire de facteurs environnementaux, biologiques, psychologiques et psychosociaux dans le diagnostic et le traitement de ce syndrome hétérogène. Le but de cet article est de donner un aperçu des connaissances actuelles et des hypothèses étiologiques destinées à mieux comprendre et mieux aider les personnes qui en souffrent. [less ▲]

Hypersensitivity to Electricity: The effect of the current waveform on the perception level

in Proceedings of the 4th Int Workshop on Biological Effects of Electromagnetic Fields (2006, October)

Hypersensitivity to electricity has been reported many times in the literature. From another point of view, numerous measurements have been performed on perception level. Even if it appears that part of ... [more ▼]

Hypersensitivity to electricity has been reported many times in the literature. From another point of view, numerous measurements have been performed on perception level. Even if it appears that part of the population has a lower perception level of current, there is no clear link with the so called “hypersensitivity to electricity” which is more related to declared physiological disorders in part of the population (sleeping problem, headache ...). Such declared hypersensitivity is currently not yet related to any biological parameter. Our research team is currently trying to determine a relationship between hypersensitive declared people and the perception level when injecting current in the low frequency range 50-1000 Hz. We have performed current perception tests with individuals under different conditions (different wave shapes, frequencies, influence of external electric field, male and female...) using a particular protocol and our own designed system for current injection. This paper will present our test system design (current injector, wave shape converter, safety aspects) and our first results based on both sine wave (different frequencies) and wide band signal. [less ▲]

Hypertension

Conference (2010, April 21)

Hypertension and pregnancy

in Acta Cardiologica (1977), 32