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See detailEvaluation of the DR-CALUX screening of food and feed, according to regulation levels including DL-PCB
Scippo, Marie-Louise ULg; Rybertt, Soledad; Focant, Jean-François ULg et al

in Organohalogen Compounds (2005), 67

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See detailEvaluation of the dynamic adsorption of gas on active carbon beds using in situ X-ray µ-tomography coupled with 3D image analysis
Almazan, Maria del Carmen; Léonard, Angélique ULg; Lodewyckx, Peter et al

Poster (2009, June)

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See detailEvaluation of the Economic Statistical Design of the Multivariate T2 Control Chart with Multiple Variable Sampling Intervals Scheme: NSGA-II Approach
Faraz, Alireza ULg; Seif, Asghar; Sadeghifar

in Journal of Statistical Computation & Simulation (2014)

The economic and statistical merits of a multiple variable sampling intervals (MVSI) scheme are studied. The problem is formulated as a double-objective optimization problem with the adjusted average time ... [more ▼]

The economic and statistical merits of a multiple variable sampling intervals (MVSI) scheme are studied. The problem is formulated as a double-objective optimization problem with the adjusted average time to signal as the statistical objective and the expected cost per hour as the economic objective. Bai and Lee’s ‎[2] economic model is considered. Then we find the Pareto-optimal designs in which the two objectives are minimized simultaneously by using the non-dominated sorting genetic algorithm. Through an illustrative example, the advantages of the proposed approach is shown by providing a list of viable optimal solutions and graphical representations, which indicate the advantage of flexibility and adaptability of our approach. [less ▲]

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See detailEvaluation of the ecotoxicological effects of POPs and heavy metals, reflecting pathological, microbiological and genetic analyses, on the Mekong River population of Irrawaddy dolphins (Orcaella brevirostris)
Siebert, Ursula; Das, Krishna ULg

Report (2011)

For this report, samples of Irrawaddy River dolphins found dead along the Mekong River between 2006 and 2010 were analysed in different laboratories in Europe, Canada and Cambodia. The aim of the ... [more ▼]

For this report, samples of Irrawaddy River dolphins found dead along the Mekong River between 2006 and 2010 were analysed in different laboratories in Europe, Canada and Cambodia. The aim of the investigation was to gain additional knowledge on histological and toxicological findings as well as on the genetic variation of the Mekong population. The report summarizes those results in relation to previous investigations conducted in Cambodia and the United States of America. [less ▲]

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See detailEvaluation of the effect of general anaesthesia on ultrasonographic images of the small intestine in horses.
Salciccia, Alexandra ULg; Gougnard, Alexandra ULg; de la Rebière de Pouyade, Geoffroy ULg et al

Poster (2011, July)

ultrasonography is currently more and more used in equine acute abdominal disease as well as in the follow-up of surgical colic patients because of its sensibility for the detection of small intestinal ... [more ▼]

ultrasonography is currently more and more used in equine acute abdominal disease as well as in the follow-up of surgical colic patients because of its sensibility for the detection of small intestinal distension. General anaesthesia is known to diminish gastrointestinal motility even if there are no clinical signs associated with it. The aim of this study was to evaluate the effect of general anaesthesia on transabdominal ultrasonographic images of the small intestine in horses undergoing routine non abdominal surgeries. The ultrasonographic exams were performed in 19 horses before and after the general anaesthesia (immediately after the recovery and then 2h, 12h and 24h after it). Each ultrasonographic exam focused on the duodenum, the jejunum and the presence of peritoneal fluid. For the jejunum, 5 locations were used: on the ventral midline just caudally to the sternum, on the left and right cranial ventral parts of the abdomen, on the left and right inguinal regions. Other parameters such as the gut sounds and the postoperative fecal output were also recorded. Anova and Chi-square tests were used for the statistical analysis. No horse showed colic signs. No significant difference was found between the pre and post anaesthetic period considering the maximal diameter of the duodenum, the maximal diameter of the jejunum on the 5 locations and the peritoneal fluid. The contractions of the duodenum were increased at the recovery compared to before the anaesthesia (p= 0,0299). The small intestine was most visible at the recovery (57,5%) and then at 2 hours after it (38,3%). It seemed that the ventral midline just caudally to the sternum and the right and left inguinal regions were the best locations to observe the jejunum (with a mean of respectively 44,6%, 39,8% and 38,5% of visualization of the jejunum).The gut sounds were very significantly decreased at the recovery (p < 0,0001) and at 2h after it (p = 0,0006). The postoperative fecal output was not decreased. In conclusion, even if general anaesthesia seems to reduce temporarily the intestinal activity (decreased gut sounds in the early post anaesthetic period), it does not cause significant distension of the small intestine (almost the small intestinal diameters were in the normal range). If an increased diameter of small intestine is observed by ultrasonography after surgery it should therefore be attributed to a pathological process and not to the anaesthesia. [less ▲]

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See detailEvaluation of the effect of load eccentricity in a tensile pull-off test on bond strength
Courard, Luc ULg; Garbacz, Andrezj

Report (2010)

The report presents the results of a research project and the impact of incorrect design on tensile strength values. According to results of laboratory experiments and modelling, it can be observed that ... [more ▼]

The report presents the results of a research project and the impact of incorrect design on tensile strength values. According to results of laboratory experiments and modelling, it can be observed that, if there is an influence of 2° and 4° angle of inclination on pull-off bond strength, it is however not statistically significant: the decrease of pull-off strength is usually no larger than 14% for 4°. [less ▲]

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See detailEvaluation of the effect of load eccentricity on pull-off strength
Moczulski, Grzegorj; Garbacz, Andrzej; Courard, Luc ULg

in Alexander, M. G.; Beushausen, H.-D.; Dehn, F. (Eds.) et al Concrete Repair, Rehabilitation and Retrofitting II (2009)

The efficiency of the composite repair system is usually evaluated through semi-destructive test: pull-off test. But some difficulties can also be induced by the eccentricity of the load application, due ... [more ▼]

The efficiency of the composite repair system is usually evaluated through semi-destructive test: pull-off test. But some difficulties can also be induced by the eccentricity of the load application, due to incorrect placement of the test device. The paper presents the results of a research project and the impact of incorrect design on tensile strength values. According to results of laboratory experiments and modelling, it can be observed that, if there is an influence of 2o and 4o angle of inclination on pull-off bond strength, it is however not statistically significant: the decrease of pull-off strength is usually no larger than 8% for 2o [less ▲]

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See detailEvaluation of the effect of two training regimes on the resumption of the ovarian activity by analysis of faecal 20 alpha-hydroxyprogesterone in trotter mares
Messina, Mariella; Prandi, Alberto; Bolelli, G. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1998), 2

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See detailAn evaluation of the effects of rural development policies in the North-East Region of Romania
Paveliuc Olariu, Codrin ULg; Ciurea, Ion Valeriu; Brezuleanu, Stejarel et al

in Advances in Agriculture & Botanics (2011), 3(1), 20-25

The European Union Common Agricultural Policy (CAP) holds as principal objectives, as they were outlined in the Treaty of Rome, the following: increase productivity, by promoting technical innovation and ... [more ▼]

The European Union Common Agricultural Policy (CAP) holds as principal objectives, as they were outlined in the Treaty of Rome, the following: increase productivity, by promoting technical innovation and ensuring optimum use of factors of production, ensure a fair standard of living for the agricultural community, stabilize agricultural markets, secure availability of agricultural supplies and provide consumers with food at reasonable prices. Over time, and depending on certain factors, new secondary objectives have been added such as: environmental protection, biodiversity, animal welfare, enhancement of rural areas. In the North-East Region of Romania, the impact of rural development policies implemented through the National Rural Development Programme (NRDP) has been assessed at regional and local level utilizing a combined analysis of statistical databases. [less ▲]

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See detailEvaluation of the efficacy and safety of etoricoxib compared with naproxen in two, 138-week randomised studies of patients with osteoarthritis
Reginster, Jean-Yves ULg; Malmstrom, K.; Mehta, A. et al

in Annals of the Rheumatic Diseases (2007), 66(7), 945-951

Objectives: To assess the efficacy and safety of etoricoxib 60 mg once daily and naproxen 500 mg twice daily over a 138- week treatment period in patients with osteoarthritis ( OA). Methods: Two 1- year ... [more ▼]

Objectives: To assess the efficacy and safety of etoricoxib 60 mg once daily and naproxen 500 mg twice daily over a 138- week treatment period in patients with osteoarthritis ( OA). Methods: Two 1- year randomised, double blind, parallel group two- part base studies ( part I 12 weeks; part II 40 weeks), followed by an 86- week extension, in patients with OA ( hip or knee) were conducted at 80 clinical centres ( 19 countries). The studies had identical designs. Patients taking placebo in part I received etoricoxib or naproxen ( 1: 1 ratio) in part II and the extension; patients taking etoricoxib or naproxen in part I continued to receive the same treatment throughout the entire length of the studies. Co- primary efficacy end points were patient global assessment of disease status, and WOMAC questionnaire pain subscale and physical function subscale ( 100 mm VAS). Efficacy over 138 weeks was assessed by graphical analysis. Safety was assessed by observation of adverse experiences and laboratory and physical evaluations. Results: 997 patients entered ( 615 completed) the base studies. Of these patients, 463 patients entered the extensions. A total of 161 and 152 patients in the etoricoxib and naproxen groups, respectively, completed 138 treatment weeks. Etoricoxib and naproxen showed similar efficacy throughout the 138 weeks of treatment. For etoricoxib and naproxen, respectively, WOMAC pain assessments were 67 and 67 mm ( baseline); 28 and 29 mm ( 1 year), and 34 and 33 mm ( 138 weeks). Results for the other efficacy end points were similar to those seen with the WOMAC pain assessments. Both etoricoxib and naproxen were generally well tolerated. Conclusion: Both etoricoxib and naproxen demonstrated long- term clinical efficacy for the treatment of OA. Etoricoxib and naproxen were generally well tolerated. [less ▲]

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See detailEvaluation of the Efficacy and Safety of Oral Tiludronate in Paget's Disease of Bone. A Double-Blind, Multiple-Dosage, Placebo-Controlled Study
Reginster, Jean-Yves ULg; Colson, F.; Morlock, G. et al

in Arthritis & Rheumatism : Arthritis Care & Research (1992), 35(8), 967-74

OBJECTIVE. To assess the optimal dosage of oral tiludronate in Paget's disease of bone. METHODS. We studied 149 patients with Paget's disease, in a double-blind, randomized, placebo-controlled trial ... [more ▼]

OBJECTIVE. To assess the optimal dosage of oral tiludronate in Paget's disease of bone. METHODS. We studied 149 patients with Paget's disease, in a double-blind, randomized, placebo-controlled trial. Patients were randomly assigned to 1 of 5 therapeutic groups: a daily dose of 100 mg, 200 mg, 400 mg, or 800 mg of oral tiludronate, or a placebo. Treatment was for 3 months, followed by 3 months of placebo-controlled followup. Serum alkaline phosphatase activity (SAP) and fasting urinary excretion of hydroxyproline/creatinine (OH/Cr) were measured monthly, as were biochemical parameters reflecting renal, hepatic, and hematologic functions. Analgesic efficacy was self-evaluated from a visual analog scale and a global pain index. RESULTS. Statistical analysis revealed that beginning at a dosage of 200 mg/day, there was a direct dose-dependent effect on the reduction of SAP and OH/Cr levels. Reduction of SAP levels was clinically significant at a dosage of 400 mg (44.9 +/- 4.2% reduction at 90 days and 49.2 +/- 4.5% at 180 days, mean +/- SEM) and at 800 mg (53.4 +/- 5% at 90 days and 59.3 +/- 4.6% at 180 days). There was a significant reduction in pain in all groups, including the group taking placebo. In only those taking 800 mg/day of tiludronate was there a significant frequency of complete resolution of pain (versus placebo). Aside from mild gastrointestinal disturbances, as experienced with other oral bisphosphonates, clinical tolerance of all 5 regimens was good. Exhaustive biochemical investigations failed to reveal significant toxicity of tiludronate up to the 800-mg daily dose investigated. CONCLUSION. Because of its significantly better antiresorptive effects and greater analgesic properties (compared with lower dosages), combined with the excellent clinical and biochemical tolerance, the 800-mg daily dose of tiludronate appears to be optimal for the treatment of Paget's disease of bone. [less ▲]

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See detailEvaluation of the endorcine disrupting chemicals contamination in the North Sea porpoise population using in vitro assays
Didimo Imazaki, Pedro Henrique ULg; Brose, François ULg; Van Der Heiden, Edwige ULg et al

Poster (2009)

During the last decades, the production endocrine disrupting chemicals reached such levels that they are now spread all over nature. They are known to be very slowly degraded, decreasing the environmental ... [more ▼]

During the last decades, the production endocrine disrupting chemicals reached such levels that they are now spread all over nature. They are known to be very slowly degraded, decreasing the environmental quality and posing ecological risks. Marine mammals inhabiting polluted environments accumulate high levels of these chemicals, so they can be considered good indicators of marine pollution. Thirteen major organochloride pollutants were chosen to make subject of this study: o,p’-DDD; p,p’-DDD; p,p’-DDE; o,p’-DDT; p,p’-DDT; HCB; α-HCH; β-HCH; γ-HCH; δ-HCH; PCB 138; PCB 153 and PCB 180. All these chemicals will have their endocrine disrupting effects characterized individually and collectively by report gene expression assays. The MCF7-ERE cells used in these assays were produced in the Molecular Biology and Genetic Engineering Laboratory of the University of Liège and are originated from a human mammary carcinoma. They carry a gene expressing the synthesis of luciferase and controlled by oestrogen receptors. Then, the thirteen chemicals will be searched in the blubber tissues of porpoises by the use of gas chromatography-mass spectrometry. The blubber samples will also have their endocrine disrupting effect characterized. For the moment, the estrogenic effects of the HCH isomers were put in evidence. The next steps of this work must be soon accomplished. It is expected a great level of these compounds to be found in the samples. On the other hand, their endocrine disrupting effects and how they act in agonist, antagonist and synergist ways are subject that still needs to be cleared. [less ▲]

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See detailEvaluation of the Enhanced Assumed Strain and Assumed Natural Strain in the SSH3D and RESS3 Solid Shell Elements for Single Point Incremental Forming Simulation
Guzmán Inostroza, Carlos Felipe ULg; Ben Bettaieb, Amine ULg; Velosa de Sena, José Ilidio et al

in Key Engineering Materials [=KEM] (2012), 504-506

Single Point Incremental Forming (SPIF) is a recent sheet forming process which can give a symmetrical or asymmetrical shape by using a small tool. Without the need of dies, the SPIF is capable to deal ... [more ▼]

Single Point Incremental Forming (SPIF) is a recent sheet forming process which can give a symmetrical or asymmetrical shape by using a small tool. Without the need of dies, the SPIF is capable to deal with rapid prototyping and small batch productions at low cost. Extensive research from both experimental and numerical sides has been carried out in the last years. Recent developments in the finite element simulations for sheet metal forming have allowed new modeling techniques, such as the Solid Shell elements, which combine the main features of shell hypothesis with a solid-brick element. In this article, two recently developed elements -SSH3D element [1, 2] and RESS3 element [3]- implemented in Lagamine (finite element code developed by the ArGEnCo department of the University of Liège) are explained and evaluated using the SPIF line test. To avoid locking problems, the well-known Enhanced Assumed Strain (EAS) and Assumed Natural Strain (ANS) techniques are used. The influence of the different EAS and ANS parameters are analysed comparing the predicted tool forces and the shape of a transversal cut, at the end of the process. The results show a strong influence of the EAS in the forces prediction, proving that a correct choice is fundamental for an accurate simulation of the SPIF using Solid Shell elements. [less ▲]

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See detailEvaluation of the exercise performed by horses during the country phase of a three-day events competition : a field study
Amory, Hélène ULg; Linden, Annick ULg; Art, Tatiana ULg et al

in Archives Internationales de Physiologie et de Biochimie (1991)

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See detailEvaluation of the function of ADAMTS-2, a metalloproteinase containing a disintegrin domain and thrombospondin type I repeats, during angiogenesis in vitro and in vivo
Kesteloot, Frédéric ULg; Lapière, Charles M; Colige, Alain ULg et al

in Acta Clinica Belgica (2004), 59(2), 120

Angiogenesis is required for development, growth, tissue remodeling, and wound healing. Pathologies such as diabetic retinopathy, rheumatoid arthritis and cancer would benefit from therapies controlling ... [more ▼]

Angiogenesis is required for development, growth, tissue remodeling, and wound healing. Pathologies such as diabetic retinopathy, rheumatoid arthritis and cancer would benefit from therapies controlling and reducing angiogenesis. Enzymes of the ADAMTS family are closely related to MMPs and ADAMs. They contain however some specific features, such as a variable number of domains known as “ThromboSpondin type I repeat” (TSPI). ADAMTS-1 and -8 are 20-fold more anti-angiogenic than angiostatin and endostatin, two potent inhibitors of angiogenesis. The primary function of ADAMTS-2 is the maturation of collagen type I and II molecules by excising the amino-propeptide. In addition, ADAMTS-2 could also modulate angiogenesis, as it contains the same sequences than those responsible for the anti-angiogenic activity of ADAMTS-1 and -8. This hypothesis was investigated in vitro in different experimental models such as cell proliferation and formation of capillary structures by human endothelial cells. An ex vivo angiogenesis model was also used. It consists in mice or rat aorta pieces embedded in a collagen gel in order to allow the growth of capillaries from the vascular endothelium. As compared to control mice (TS2+/+), angiogenesis was slightly increased, in absence of ADAMTS-2, from aortas of ADAMTS-2 KO mice (TS2-/-). Using rat aortas, addition of recombinant ADAMTS-2 reduced the formation of capillary structure, also confirming the anti-angiogenic activity of ADAMTS-2. Finally, an in vivo model of angiogenesis was also used. Biocompatible sponges (Ivalon) were implanted under the skin of TS2+/+ or TS2-/- mice in order to evaluate the formation of capillaries in the granulation tissue invading the sponge. In absence of ADAMTS-2, angiogenesis and granulation tissue formation were both reduced. Additional investigations are being performed in order to identify the underlying mechanism(s) inducing these modifications. [less ▲]

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See detailEvaluation of the genetic diversity of honey bees, Apis mellifera L. in the Walloon Region and selection of strains tolerant to the mite Varroa destructor Anderson and Trueman
Leclercq, Gil ULg; Nguyen, Bach Kim ULg; Gengler, Nicolas ULg et al

Poster (2012, February 10)

For more than a decade, high losses of honey bee colonies have been noticed in several countries, including Belgium. Currently often the mite Varroa destructor is considered a main threat for beekeeping ... [more ▼]

For more than a decade, high losses of honey bee colonies have been noticed in several countries, including Belgium. Currently often the mite Varroa destructor is considered a main threat for beekeeping. In view of the inefficiency of the current chemical treatments, one of the solutions is to select honey bees tolerant to this parasite using genomic selection. To reach this objective the genetic diversity of honey bees needs first to be studied using mainly ‘Single Nucleotide Polymorphisms’ (SNP). Records and samples will be collected all over the Walloon Region in order to create an informative phenotypic and genomic data base that will be used for ‘Genome Wide Association Studies’ (GWAS) to detect associations between SNPs and tolerance, and to select bees tolerant to Varroa destructor. [less ▲]

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See detailEvaluation Of The Genetic Variability Of 23 Bovine Microsatellite Markers In Four Belgian Cattle Breeds
Peelman, Lj.; Mortiaux, F.; Van Zeveren, A. et al

in Animal Genetics (1998), 29(3),

Detailed reference viewed: 18 (3 ULg)