Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailAn Evolutive Software Environment for Teaching the Finite Element Method in Electromagnetism
Dular, Patrick ULg; Geuzaine, Christophe ULg; Genon, André ULg et al

in IEEE Transactions on Magnetics (1999), 35(3), 1682--1685

Detailed reference viewed: 30 (0 ULg)
Peer Reviewed
See detailAn Evolutive Software Environment for Teaching the Finite Element Method in Electromagnetism
Dular, Patrick ULg; Geuzaine, Christophe ULg; Genon, André ULg et al

in Proceedings of the Eighth Biennal IEEE Conference on Electromagnetic Field Computation (1998)

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailEVOLVE: entre déception et optimisme
DELANAYE, Pierre ULg; Krzesinski, Jean-Marie ULg; CAVALIER, Etienne ULg

in Néphrologie & Thérapeutique (2013), 9(4), 241-245

Detailed reference viewed: 13 (6 ULg)
Full Text
Peer Reviewed
See detailThe evolved early-type binary HDE 228766 revisited
Rauw, Grégor ULg; Crowther, P. A.; Eenens, P. R. J. et al

in Astronomy and Astrophysics (2002), 392(2), 563-574

We use an extensive set of spectroscopic observations to reinvestigate the properties of the massive binary HDE 228766. Conventional classification criteria suggest that HDE 228766 consists of an O7 ... [more ▼]

We use an extensive set of spectroscopic observations to reinvestigate the properties of the massive binary HDE 228766. Conventional classification criteria suggest that HDE 228766 consists of an O7 primary and an Of(+) secondary. However, several spectral features of the secondary, such as the simultaneous presence of N III, N IV and N V emissions, make it a rather unusual object. We find that the orbital motion of the secondary is probably best described by the radial velocities of the narrow N III emission lines. Our orbital solution yields m(1) sin(3) i = 31:7 and m(2) sin(3) i = 25:5 M. for the primary and secondary respectively. The He II lambda 4542 absorption in the secondary's spectrum appears considerably blue-shifted with respect to the narrow emission lines, indicating that the absorption is probably formed in the accelerating part of the secondary's wind. We use a tomographic technique to investigate the profile variability of the broader emission lines. In addition to a strong emission from the secondary, the Halpha line displays a weak emission feature that is probably associated with a wind interaction region located near the surface of the primary star. Finally, our analysis of the spectrum with a non-LTE code indicates that the secondary is an evolved object that exhibits some CNO processed material in its atmosphere and has a large mass loss rate. Assuming a distance of 3.5 kpc (which follows from adopting M-V,M-s = -6 for the secondary) we infer (M) over dot similar or equal to 10(5) M. yr(-1) for the secondary. Our results suggest that HDE 228766 could be in a post-Roche lobe overflow stage. The secondary may be classified as WN8ha and is currently in a transition stage between a "normal" Of staranda WNL-type Wolf-Rayet star. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailEvolving definitions of remission in Crohn's disease.
Panaccione, Remo; Colombel, Jean-Frederic; Louis, Edouard ULg et al

in Inflammatory bowel diseases (2013), 19(8), 1645-53

BACKGROUND: Using clinical symptoms alone to inform treatment decisions in Crohn's disease (CD) may increase the risk of disease progression and complications. Treatment beyond symptoms may offer improved ... [more ▼]

BACKGROUND: Using clinical symptoms alone to inform treatment decisions in Crohn's disease (CD) may increase the risk of disease progression and complications. Treatment beyond symptoms may offer improved outcomes. METHODS: We explore alternative definitions of remission, beyond traditional clinical remission, incorporating more objective parameters of inflammation control, which may support prevention or delay the disease progression. These definitions could serve as a platform for future clinical research, evaluating whether treating beyond symptoms alters the natural history of CD. RESULTS: Proposed definitions may include endoscopic remission (mucosal healing), normalization of serologic or fecal markers of inflammation, and even radiographic remission, in addition to clinical remission (symptom control). Endoscopic remission is the leading candidate for inclusion because it is the best studied. The definition should include considerations for both early and late disease given that in late disease, which may be associated with operation-related symptoms or irreversible bowel damage, symptomatic remission may not achievable. Desired outcomes in early disease are complete absence of symptoms, no disease progression, no complications or disability, and normal quality of life. In late disease, there are stabilization of noninflammatory symptoms, no progression of damage or disability, and improved quality of life. CONCLUSIONS: Over time, we anticipate that a working definition of remission that includes both biological remission and clinical remission will evolve and be evaluated in clinical trials. Our proposed definition is a possible starting point for that evolution. Ultimately, the goal in evolving the definition of remission is to improve the outcomes in patients with CD. [less ▲]

Detailed reference viewed: 8 (0 ULg)
See detailEvolving science, technology and innovation policies in Belgium: a comparative study
Charlier, Nathan ULg

Conference (2013, April)

Science, technology and innovation (STI) policies have gone through deep changes since the early 80’s. Multiple scholars have shown that there are new forms of links, or a renewed “contract” between ... [more ▼]

Science, technology and innovation (STI) policies have gone through deep changes since the early 80’s. Multiple scholars have shown that there are new forms of links, or a renewed “contract” between science, as an institution, and the society: effects of neoliberalism, public controversies or technology assessment (TA) practices are some common features of this transformation. Innovation is pushed forward by policymakers as a crucial tool for economic growth and competitiveness of political entities. In other words, there is a new regime of STI governance. As a PhD student, I investigate the policies of science and innovation in Belgium. Since the regionalization of these competences in the 1980’s, the STI regimes have evolved separately in Flanders and Wallonia. The goal of my research is to depict and compare how constitutive elements of the regimes such as discourses, tools, institutions, networks, etc. have changed in the two Regions. Adopting a cognitive approach in policy analysis, I focus on the imaginaries or master narratives that shape programs and individuals at different policy levels. These levels range from the “micro” (individual interactions in the institutions) to the “macro” (the EU and OECD), the “meso” level being the core of the research question (regional programs and institutions). I seek to point out the local enactment of ideas such as “regional competitiveness”, “innovation-led growth”, “clustering” and its impact on STI regime. The research relies on document analysis, participant observation, and in depth semi-structured interviews designed as life stories of key STI informants. [less ▲]

Detailed reference viewed: 52 (8 ULg)
Peer Reviewed
See detailEvolving trends in Latin American politics of biotechnologies: delving into the “GM soya model” in Argentina
Delvenne, Pierre ULg; Vara, Ana Maria; Vasen, Federico

Conference (2011, November 02)

Our interest is to understand the challenges to modern science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly attention has been ... [more ▼]

Our interest is to understand the challenges to modern science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly attention has been paid to existing institutions that may no longer be adequate to address those challenges. This may be because modern institutions are pressured for a greater reflexive opening up of their structures (Beck and Lau 2005) or because the modern world-system is facing severe turbulences that would ultimately lead to a time of structural dissolution (Wallerstein 2005). This renders it interesting to trace the responses to these challenges, and we suggest doing it in the field of STS. Our ongoing multi-level comparative research takes Latin American countries as an entrance point to finding responses that are different from those occurring in European countries. Our presentation is based on Argentina and it focuses on biotechnology in agriculture. Argentina today is the second largest exporter of GM crops and it has been the first country in Latin America to establish a professional regulatory framework in the early 1990s. GM soya crop is specifically analysed because of its importance — more than 60% of the cultivated areas — and its controversial aspect : it is presented at the same time as an elixir for agro-industrial ills and as a techno-economic network increasing the benefits of the global North while dramatically affecting public health and the environment. We suggest diagnosing developments and perceptions of issues related to health, economy, ecological diversity, fertility of soils, regulation and intellectual property. [less ▲]

Detailed reference viewed: 24 (2 ULg)
Full Text
See detailEvolving trends in Latin American regimes of science, technology and innovation: the politics of the “GM soya model” in Argentina
Delvenne, Pierre ULg

Conference (2011, June 16)

Our interest is to understand the challenges to modern (national) science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly ... [more ▼]

Our interest is to understand the challenges to modern (national) science and innovation regimes under conditions of globalization and “multiple modernities” (Eisenstadt 2000). Different scholarly attention has been paid to existing institutions that may no longer be adequate to address those challenges. This may be because modern institutions are pressured for a greater reflexive opening up of their structures (Beck and Lau 2005) or because the modern world-system is facing severe turbulences that would ultimately lead to a time of structural dissolution (Wallerstein 2005). This renders interesting to trace the responses to these challenges, and we suggest to do it in the field of science, technology and society, one where we can make a contribution. Unlike many studies mainly focusing on European models and regimes, our ongoing multi-level comparative research takes Latin American countries as an entrance point to finding responses that are different from those occuring in European countries. Latin American countries are interesting to study in this respect because institutions of science and technology have not been set up in the same way as in Europe and the governance patterns have been different. Our presentation is based on one country, Argentina, and focuses on one important sector: biotechnology in agriculture. Argentina is taken as a central case study because in addition of being today the second largest exportator of GM crops (behind the US and before Brasil), it has been the first country in Latin America to establish a professional regulatory framework in the early 1990s, looking at ecological, health and commercial aspects. GM soya crops is specifically analysed because of its importance — GM soya represents 60% of the cultivated areas — and its controversial aspect : the « GM soya model » is presented at the same time as an elixir for agro-industrial ills and as a techno-economic network increasing the benefits of the global North while dramatically affecting public health and the environment in Argentina. We suggest to diagnose developments and perceptions of issues related to health, economy, ecological diversity, fertility of soils, regulation and intellectual property. Our methodology favours qualitative data collection (individual interviews with key actors of science and innovation) and analysis, while using quantitative data when available and relevant. [less ▲]

Detailed reference viewed: 21 (3 ULg)
See detailEx iusta causa traditum: Essays in Honour of Eric H. Pool
Van den Bergh, Rena; van Niekerk, Gardiol; Thomas, Philip et al

Book published by UNISA (2005)

Detailed reference viewed: 100 (0 ULg)
Peer Reviewed
See detailEx vivo bioluminescent detection of alcelaphine herpesvirus 1 infection during malignant catarrhal fever induced in rabbits
Dewals, Benjamin G ULg; Myster, Françoise ULg; Massart, François et al

Poster (2009, December 11)

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. Experimentally, WD-MCF can be reproduced in rabbits. The lesions observed are very similar to those described in natural host species. Recently, we demonstrated that WD-MCF induced by AlHV-1 in rabbits is associated with the proliferation of CD8+ cells supporting a latent type of infection. In the present study, we investigated whether the virus could be detected ex vivo in the tissues of rabbits developing WD-MCF. Taking advantage of the recent cloning of the AlHV-1 genome as a bacterial artificial chromosome (BAC), we produced a recombinant plasmid encoding a firefly luciferase (LUC) expression cassette inserted in a non-coding region of the AlHV-1 genome. In vitro, the reconstituted AlHV-1 LUC strain replicated comparably to the parental strain in permissive cells and was able to induce a bioluminescent signal. In vivo, rabbits infected with the AlHV-1 LUC strain developed WD-MCF similarly to the parental wild-type strain with hyperthermia, increased CD8/CD4 ratio and viral genomic charge over time in PBMC and in lymph nodes at time of death. To identify the presence of AlHV-1 infection ex vivo, various organs of infected rabbits developing WD-MCF were analysed by bioluminescent imaging. Luciferase activity could be detected macroscopically at the time of death in most of analyzed organs including lung, popliteal and mesenteric lymph nodes, spleen, liver, kidney and appendix. Infectious virus could be isolated following co-cultures of lymph node and permissive cells, and the isolated virus retained the ability to induce a bioluminescent signal. In conclusion, we produced an AlHV-1 LUC recombinant and we were able to detect the AlHV-1 infection ex vivo in many organs at the time of death. [less ▲]

Detailed reference viewed: 51 (25 ULg)
Full Text
Peer Reviewed
See detailEx vivo bioluminescent detection of Alcelaphine herpesvirus 1 infection during malignant catarrhal fever.
Dewals, Benjamin G ULg; Myster, Françoise ULg; Palmeira, Leonor ULg et al

in Journal of Virology (2011), 85(14), 6941-54

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla ... [more ▼]

Alcelaphine herpesvirus 1 (AlHV-1), carried by wildebeest asymptomatically, causes malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. Experimentally, WD-MCF can be reproduced in rabbits. WD-MCF is described as a combination of lymphoproliferation and degenerative lesions in virtually all organs and caused by unknown mechanisms. Recently, we demonstrated that WD-MCF is associated with the proliferation of CD8(+) cells supporting a latent type of infection in lymphoid tissues. Here, we investigated the macroscopic distribution of AlHV-1 infection using ex vivo bioluminescence imaging in rabbit to determine whether it correlates with the distribution of lesions in lymphoid and non-lymphoid organs. To reach that goal, a recombinant AlHV-1 strain was produced by insertion of a luciferase expression cassette (luc) in an intergenic region. In vitro, the reconstituted AlHV-1 luc(+) strain replicated comparably to the parental strain and luciferase activity was detected by bioluminescence imaging. In vivo, rabbits infected with the AlHV-1 luc(+) strain developed WD-MCF comparably to the parental wild-type strain with hyperthermia and increase of both CD8(+) T cells frequencies and viral genomic charge over time in peripheral blood mononuclear cells and in lymph nodes at time of euthanasia. Bioluminescent imaging revealed that AlHV-1 infection could be detected ex vivo in lymphoid organs but also in lung, liver and kidney during WD-MCF, demonstrating that AlHV-1 infection is prevalent in tissue lesions. Finally, we show that the infiltrating mononuclear leukocytes in non-lymphoid organs are mainly CD8(+) T cells and that latency is predominant during WD-MCF. [less ▲]

Detailed reference viewed: 67 (28 ULg)
Full Text
Peer Reviewed
See detailEx Vivo Evaluation of p-[18F]D-MPPF for the Study of 5-HT1A Receptors.
Defraiteur, C.; Lemaire, Christian ULg; Luxen, André ULg et al

in Journal of Labelled Compounds & Radiopharmaceuticals (2005), 48

Detailed reference viewed: 11 (3 ULg)
Full Text
Peer Reviewed
See detailEx vivo expansion of hematopoietic progenitor cells is associated with downregulation of alpha4 integrin- and CXCR4-mediated engraftment in NOD/SCID beta2-microglobulin-null mice
Foguenne, Jacques ULg; Di Stefano; Giet, Olivier ULg et al

in Haematologica (2009), 94

Several studies indicate that ex vivo cytokine-supported expansion induces defective hematopoietic stem cell engraftment. We investigated the role of alpha4 integrin, alpha5 integrin and CXCR4 in ... [more ▼]

Several studies indicate that ex vivo cytokine-supported expansion induces defective hematopoietic stem cell engraftment. We investigated the role of alpha4 integrin, alpha5 integrin and CXCR4 in engraftment of unmanipulated and cytokine-treated human cord blood CD34+ cells. [less ▲]

Detailed reference viewed: 39 (18 ULg)
Full Text
Peer Reviewed
See detailEx vivo ruminal cellulosome for by-product biomass conversion
Hissette, Mathias ULg; Destain, Jacqueline ULg; Thewis, André ULg et al

Conference (2011, April 27)

Detailed reference viewed: 53 (16 ULg)
Full Text
Peer Reviewed
See detail(Ex)communication
Dumortier, Jean-Louis ULg

in Lettre de la DLFM (2003), 32

Detailed reference viewed: 6 (2 ULg)
Full Text
Peer Reviewed
See detail(Ex-)smoking asthma patients in general and specialized Belgian practice.
Decramer, M.; Louis, Renaud ULg; Joos, G. et al

in Respiratory medicine (2011), 105(8), 1203-1210

INTRODUCTION: Smokers are often excluded from asthma studies. In the present study, data are presented on the prevalence, characteristics and management approach of this patient population in the Belgian ... [more ▼]

INTRODUCTION: Smokers are often excluded from asthma studies. In the present study, data are presented on the prevalence, characteristics and management approach of this patient population in the Belgian practice both at the level of general practitioners (GPs) and specialists. MATERIALS AND METHODS: One hundred and nineteen smoking, non-smoking and ex-smoking patients (25-65 yrs) with asthma, COPD or both, were recruited by 33 GPs and 33 specialists. Data were obtained retrospectively from medical records. However, only a small number of files were complete. RESULTS: The majority of COPD patients were (ex-)smokers: 94% in the specialist group, 78% in the GP group. Cardiovascular comorbidity appeared in both groups in the same frequency order: COPD>(ex-)smoking patients with asthma (AS)>non-smoking patients with asthma (ANS), with a significant difference between AS and ANS in the specialist population. Chronic cough during more than 3 months in two consecutive years was reported in 97% of COPD patients, in 71% of the AS patients and in only 25% of the ANS patients. The type of cough differed between AS and ANS in the GP group, with a higher prevalence of productive cough in the former. Treatment patterns observed were as expected according to diagnosis except for a disproportionate use of Tiotropium in AS in the GP group. CONCLUSION: AS were somewhere in between COPD patients and ANS for a large number of the characteristics studied, suggesting that they are an intermediate phenotype between COPD and asthma. [less ▲]

Detailed reference viewed: 26 (16 ULg)
Peer Reviewed
See detailEx-vivo cytokine production by whole blood cells from cancer patients
De Groote, Donat; Vrindts-Gevaert, Yvonne; Lopez Y Cadenas, Miguel ULg et al

in Cancer Detection & Prevention (1996), 20

Detailed reference viewed: 21 (6 ULg)
Full Text
Peer Reviewed
See detailLes exacerbations dans la BPCO: un fardeau a reduire
Corhay, Jean-Louis ULg; Nguyen Dang, Delphine ULg; Louis, Renaud ULg

in Revue Médicale de Liège (2006), 61(10), 691-6

Exacerbations of chronic obstructive pulmonary disease (COPD) play a very important role. Unfortunately they were neglected a long time in the therapeutic tests. However exacerbations influence the ... [more ▼]

Exacerbations of chronic obstructive pulmonary disease (COPD) play a very important role. Unfortunately they were neglected a long time in the therapeutic tests. However exacerbations influence the decline of the respiratory function over time, cause important deterioration of the quality of life of the patients, increase morbidity and mortality of COPD, and finally represent a burden for health care. Reducing the number of exacerbations could potentially slow down the progression of the disease. Thus the prevention of exacerbations should be the "corner stone" of the maintenance treatment of the COPD. In this review we propose to recall the importance of exacerbations in COPD and to present the treatment which have been shown to reduce exacerbation rate in COPD. [less ▲]

Detailed reference viewed: 85 (5 ULg)
Peer Reviewed
See detailAn exact bi-directional dynamic programming algorithm for an elementary shortest path problem with variable service start time
Arda, Yasemin ULg; Crama, Yves ULg; Kucukaydin, Hande ULg

Conference (2014, January 31)

We consider an elementary shortest path problem with resource constraints (ESPPRC), where a capacitated single vehicle serves customers by respecting their associated time windows. The vehicle can start ... [more ▼]

We consider an elementary shortest path problem with resource constraints (ESPPRC), where a capacitated single vehicle serves customers by respecting their associated time windows. The vehicle can start servicing the customers at any desired time, but it can be used for a fixed amount of time. The total transportation cost depends on the total distance traveled and the total amount of time that the vehicle spends by performing the assigned trip. On the other hand, each served customer yields a revenue. Thus, the aim is to identify the path to be followed and the start time of the vehicle from the depot that minimize the total transportation cost minus the gained revenues. This kind of a problem can be encountered as a pricing subproblem when a branch-and-price algorithm is applied to solve vehicle routing problems with additional constraints. In such a case, the revenues correspond to the dual prices of the visited vertices. It is known that the classical ESPPRC can be solved to optimality by implementing a dynamic programming (DP) algorithm. However, our problem has to take an infinite number of Pareto-optimal states into consideration, since the vehicle can leave the depot at any point in time and charges depending on the total traveling and waiting time. We propose an exact DP algorithm which can deal with an infinite number of Pareto-optimal states by representing total traveling and waiting time as a piecewise linear function of the service start time at the depot and develop suitable dominance rules. Furthermore, a column generation algorithm is devised for solving the relaxed set covering formulation of the related vehicle routing problem where new columns are determined by the proposed DP algorithm. Finally, computational results are presented. [less ▲]

Detailed reference viewed: 29 (0 ULg)