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See detailEvaluation of decision methodologies for analytical method validation
Rozet, Eric ULg; Rudaz, S.; Bouabidi, A. et al

Poster (2009)

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See detailEvaluation of deep water circulation with natural C-14 and helium-3 during OCMIP-2
Dutay, J.-C; Jean-Baptiste, P; Maier-Reimer, E. et al

Conference (2002, May)

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See detailEvaluation of dental pulp temperature rise during photo-activated decontamination (PAD) of caries: an in vitro study.
Nammour, S.; Zeinoun, T.; Bogaerts, I. et al

in Lasers in Medical Science (2009)

Photo-activated decontamination (PAD) has been reported in caries treatment as an aid in dentine decontamination. The aim of this study is to verify the harmlessness for pulp vitality of photo-activated ... [more ▼]

Photo-activated decontamination (PAD) has been reported in caries treatment as an aid in dentine decontamination. The aim of this study is to verify the harmlessness for pulp vitality of photo-activated decontamination (PAD) in caries treatment. Twenty freshly extracted single-rooted teeth were used. Deep class I cavities with a </= 0.5 mm dentine thickness between the floor of the cavity and the roof of cameral pulp were prepared. Following the manufacturer's instructions, cavities were filled with a photo-sensitizer (Phenothiazinechloride: 10 mg /ml), irradiated during 30 s with a 660-nm diode laser (output power: 40 mW in continuous wave; total delivered energy density: 4.87 J/cm(2)). Pulp temperature raises were recorded using a thermocouple (ALCr). Measurements were recorded every second during the irradiation and 150 s afterwards. Six records were repeated for each tooth. After 30 s of irradiation, the mean of temperature rise was 0.83 degrees C +/- 0.22 degrees C. All records showed temperature increases lower than the 3 degrees C (safety level for pulp injury). Based on our in vitro study, we can conclude that the dental pulp temperature rise following the use of PAD technique for the decontamination of dentine can be considered as save procedure for pulp vitality. [less ▲]

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See detailEvaluation of dietary stevioside supplementation on anti-human serum albumin immunoglobulin G, Alpha-1-glycoprotein, body weight and thyroid hormones in broiler chickens.
Daneshyar, M.; Geuns, J. M. C.; Willemsen, H. et al

in Journal of Animal Physiology & Animal Nutrition (2012), 96(4), 627-33

Sixty male broiler chickens fed a diet supplemented with 130 mg/kg stevioside (S group) or an unsupplemented diet (C group) from day 1 of age onwards. On day 21 of age, ten birds from either the S (SH) or ... [more ▼]

Sixty male broiler chickens fed a diet supplemented with 130 mg/kg stevioside (S group) or an unsupplemented diet (C group) from day 1 of age onwards. On day 21 of age, ten birds from either the S (SH) or C (CH) group were injected subcutaneously with 100 mug human serum albumin (HSA) and ten others from either S (SP) or C (CP) group injected with 100 mul phosphate-buffered saline (PBS) in the same way. There were no significant effect of supplementation nor interaction with age on average body weights, T(3) and T(4) concentrations of non-injected chickens. After the primary immunization, alpha(1) -glycoprotein concentrations increased in all treatment groups except the CP group, and were significantly higher in the CH group in relation to the other groups. Fourteen and 18 days after the primary immunization, HSA injected chickens of both dietary treatments had significantly higher anti-HSA immunoglobulin G (IgG) levels than their PBS injected controls. No effect of stevioside supplementation was observed for IgG level. In conclusion, dietary stevioside inclusion can attenuate the pro-inflammatory response after stimulation of the innate immune response in broiler chickens. [less ▲]

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See detailEvaluation of different advanced finite element concepts for detailed stress analysis of laminated composite structures
Rah, K.; Van Paepegem, W.; Habraken, Anne ULg et al

in International Journal of Material Forming (2009), volume 2(Supplément 1), 943-947

Despite their high specific stiffness and strength, laminated composite materials, e.g. fibre-reinforced plastic plies stacked at different fibre orientations, are susceptible to damage. Damage can be ... [more ▼]

Despite their high specific stiffness and strength, laminated composite materials, e.g. fibre-reinforced plastic plies stacked at different fibre orientations, are susceptible to damage. Damage can be divided into interalaminar damage and interlaminar damage. Delamination is a typical kind of interlaminar damage which occurs in laminated composite materials, often accompanied with intralaminar damage, and may lead to a catastrophic structural collapse. The first and most crucial step in the prediction of failure of Laminated Composite Structures (LCS) is to accurately determine the stresses, particularly the three transverse stress components, also called the interlaminar stresses. It is proposed in the present paper that the integration of a displacement based solid-shell formulation and partial-hybrid stress formulation will lead to an accurate and robust solid-shell element, suitable for the efficient and detailed interlaminar stress calculation. [less ▲]

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See detailEvaluation of different bone markers in hemodialyzed patients
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Collette, Julien ULg et al

in Clinica Chimica Acta (2006), 371(1-2), 107-111

Background: Routinely, nephrologists rely on different biochemical markers like intact PTH (iPTH), bone-specific alkaline phosphatase (BALP), plasmatic calcium and phosphate. The aim of the present study ... [more ▼]

Background: Routinely, nephrologists rely on different biochemical markers like intact PTH (iPTH), bone-specific alkaline phosphatase (BALP), plasmatic calcium and phosphate. The aim of the present study was to evaluate different other bone markers like N-terminal propeptide of type I procollagen (PINP), active isoform 5b of the tartrate-resistant acid phosphatase (TRAP 5b) and beta-crossLaps (R) (CTXS) as well as full-length PTH (wPTH), presumed non-(1-84) PTH, and their ratio in the diagnosis of renal osteodystrophy with high and low turnover. We also determined 25 hydroxyvitamin D (25VTD), 1-25 dihydroxyvitamin D and homocystein (HCY). Methods: We performed those parameters on 73 patients with end-stage renal disease according to the manufacturers' instructions. Results: There were very strong correlations between the bone markers concentrations, particularly between BALP and PINP (r=0.953). We did not observe any correlation between the ratio whole PTH/non-(1-84) PTH and any of the usual bone markers. This ratio was significantly (p < 0.05) higher in low and high bone turnover patients than in normal patients according to the K/DOQI. We found a correlation between low levels of 25VTD and high levels of HCY Conclusions: BALP offers the best clinical and analytical profile as the easier marker of choice in hemodiallyzed patients for the diagnosis of bone disease. (c) 2006 Elsevier B.V All rights reserved. [less ▲]

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See detailEvaluation of dispersant efficiency for aqueous alumina slurries by concurrent techniques
Gaydardzhiev, Stoyan ULg; Ay, Peter

in Journal of Dispersion Science & Technology (2006), 27(3), 413-417

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See detailEVALUATION OF EARTHQUAKE- TRIGGERED LANDSLIDES IN EL SALVADOR USING A GIS- BASED NEWMARK MODEL
Garcia-Rodriguez, MJ; Havenith, Hans-Balder ULg; Benito, B.

in The 14th World Conference on Earthquake Engineering (2008, October)

In this work, a model for evaluating earthquake-triggered landslides hazard following the Newmark methodology is developed in a Geographical Information System (GIS). It is applied to El Salvador, one of ... [more ▼]

In this work, a model for evaluating earthquake-triggered landslides hazard following the Newmark methodology is developed in a Geographical Information System (GIS). It is applied to El Salvador, one of the most seismically active regions in Central America, where the last severe destructive earthquakes occurred in January 13th and February 13th, 2001. The first of these earthquakes triggered more the 500 landslides and killed at least 844 people. This study is centred on the area (10x6km) where the most tragic landslide occurred (Las Colinas landslide). The model is based on the Newmark method, which treats a potential landslide as a rigid block sliding on an inclined plane. It requires inputs characterizing the geological conditions and the intensity of earthquake ground motions. The procedure includes factors such as earthquake magnitude, source-site distance, strength of geologic materials, ground water conditions and slope. The data set used in the application includes an earthquake-triggered landslides inventory for the 2001 earthquakes, a 1:100,000-scale geologic map of the region, digital cartography, strong-motion records, data on engineering properties of geologic units, and high-resolution (10 m) digital elevation models of the topography, all of them integrated in the GIS. Displacements of possible landslides along the slope (Newmark displacements) are computed from the Arias Intensity (Ia), and the Critical Acceleration (ac); the latter is inferred from the Factor of Safety (Fs). Newmark displacements have been applied to predict a landslide hazard map at regional scale, in areas where ground-shaking and geological conditions are well known. [less ▲]

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See detailEvaluation of Eddy Losses Due to High Current Leads in Transformers Using a Subproblem Method
V.Ferreira da Luz, Mauricio; Dular, Patrick ULg; Dang, Quoc Vuong ULg et al

in ISEF 2011 - XV International Symposium on Electromagnetic Fields in Mechatronics, Electrical and Electronic Engineering (ISEF2011 ) (2011, September)

A subproblem finite element method is developed for evaluating the eddy losses due to high current leads in transformers. The structural component of the transformer is modeled with classical volumetric ... [more ▼]

A subproblem finite element method is developed for evaluating the eddy losses due to high current leads in transformers. The structural component of the transformer is modeled with classical volumetric elements or more efficiently with a thin shell model (surface impedance technique). Tools are then developed to correct the inaccuracies near edges and corners inherent to thin shell models for magnetodynamic problems. Improvements of local fields make possible accurate calculations of eddy losses and of temperature rise. [less ▲]

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See detailEvaluation of efficacy and safety of oral tiludronate in Paget's disease of bone: a double-blind, dose-ranging, placebo-controlled study
Reginster, Jean-Yves ULg; Colson, F; Morlock, G et al

in Arthritis and Rheumatism (1993), 36

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See detailEvaluation of elbow biomechanical models using data fusion: Application to elbow flexion
Leboucher, Julien; Schwartz, Cédric ULg; Brochard, Sylvain et al

in Gait & Posture (2009), 30(2009), 60-61

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See detailEvaluation of Electronic Nose Technology for Early-warning of Bio-methanation Process Disturbance
Adam, Gilles ULg

Doctoral thesis (2013)

An electronic nose (e-nose) is an instrument composed of an array of non specific gas sensors inspired by the biological olfactory system for the detection and recognition of odours. In this work, this ... [more ▼]

An electronic nose (e-nose) is an instrument composed of an array of non specific gas sensors inspired by the biological olfactory system for the detection and recognition of odours. In this work, this technology is evaluated to predict process disorders in agricultural anaerobic digestion reactors. Response of the sensor array is used to recognize a gas mixture by the use of multivariate data analysis techniques. In our case, an e-nose developed in our laboratory and composed of metal oxide semi-conductor gas sensors was equipped with a biogas dilution system to realize the measurements. When employed on small-scale digesters fed with simple feeding substrates (sucrose, lipids, mixture lipids and sucrose), the e-nose presented enthusiastic results for the detection of organic overload disorders. Multivariate process control charts were employed with the e-nose data to obtain a simple state indicator represented by the Hotelling's T² statistics. This indicator resumes the general state of the digesters when its value exceeds statistically defined control limit. Instability periods and recovery of the anaerobic digestion process when exposed to organic overfeeding could be thus precisely assessed. In addition, the use of a variety of substrates had no significant effect on the performance of the e-nose monitoring. Variations of methane content in biogas, as a result of use of substrates of different compositions, had neither any influence on the e-nose monitoring quality. Thereafter, an e-nose was placed online on continuously stirred tank reactor of 100 L over a period of 300 days. A multivariate monitoring method using recursive and adaptive principal component analysis (PCA) was applied to the e-nose data. This enabled to very efficiently compensate system drift and notably sensor drift. Moreover, adaptive PCA model could also adapt to environmental variations and to reactor slow shifts. T² statistics and its squared prediction error (SPE) obtained from the PCA model are very competitive state indicators compared to pH, alkalinity, gas production rate and methane and carbon dioxide content. Two electronic noses were also evaluated in real-scale agricultural anaerobic digestion plants. The low process state monitoring in both plants does not enable to conclude to the relevance of disorders observed by the e-nose apparatus and demonstrates the real need for online anaerobic digestion process state monitoring and its subsequent optimization in agricultural biogas plants. Even though, the performance of the recursive PCA monitoring is much superior to that of static PCA. Adaptive PCA proves to be a potential automatic drift and environmental variations correction method for online and real-time e-nose measures, notably for field applications. In conclusion, it was demonstrated in this work that e-nose technology has a real potential as an application of online monitoring of anaerobic digester state. Moreover, this research demonstrated that it was possible to realize a monitoring of the state of anaerobic digesters using only gas phase measurements. Another contribution is the use of multivariate process control techniques on e-nose data to obtain a simple state indicator as well as the use of adaptive PCA to automatically compensate drift and environmental effects on e-nose measurements. [less ▲]

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See detailEvaluation of erythroid marrow response to recombinant human erythropoietin in patients with cancer anaemia.
Ponchio, L.; Beguin, Yves ULg; Farina, G. et al

in Haematologica (1992), 77(6), 494-501

BACKGROUND. Anaemia is a frequent finding in patients with cancer and may be due to different causes, including blunted erythropoietin production. MATERIALS AND METHODS. In a pilot study, we administered ... [more ▼]

BACKGROUND. Anaemia is a frequent finding in patients with cancer and may be due to different causes, including blunted erythropoietin production. MATERIALS AND METHODS. In a pilot study, we administered recombinant human erythropoietin (rHuEPO) to twelve patients with solid tumours and secondary anaemia. rHuEPO was given subcutaneously 5 d per week at escalating doses (75 to 150 U/kg per day): the aim of treatment was a Hb level > or = 10 g/dl without blood transfusion. We evaluated endogenous EPO production through serum EPO levels and erythroid marrow activity by means of serum transferrin receptor (TfR). RESULTS. Six out of 12 subjects had defective endogenous EPO production. All patients but two responded to treatment with steady increases in Hb levels above 10 g/dl, and the median dose of rHuEPO required for correction of anaemia was 75 U/kg. Response was associated with an early increase in serum TfR. Six patients developed functional iron deficiency and required iron supplementation to obtain response. Treatment improved functional ability in 4/10 responders. CONCLUSIONS. Subcutaneous rHuEPO can stimulate erythroid marrow activity in cancer anaemia, even in patients with advanced disease, and marrow response can be adequately monitored by serum TfR. Functional iron deficiency as a cause of nonresponse to rHuEPO is frequent in these patients and may require parenteral iron administration. Although erythropoietin can improve the anaemia of cancer, the decision to treat should be individualised for each patient, looking more at the quality of life and cost-effectiveness than at cosmetic increases in the haemoglobin level. [less ▲]

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See detailEvaluation of Etest for susceptibility testing of Mycobacterium tuberculosis and mycobacteria other than tuberculosis
MELIN, Pierrette ULg; Dirickx, Corine; Godefroid, Olivier et al

Conference (1996, September)

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See detailEvaluation of Everolimus (EVE) in HER2+ advanced breast cancer (BC) with activated PI3K/mTOR pathway : exploratory biomarker observations from the BOLERO-3 trial
JERUSALEM, Guy ULg; ANDRE, Fabrice; CHEN, David et al

in European Journal of Cancer (2013, September), 49(Supplement 3), 8

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See detailThe evaluation of Fair Trade as a Development Project– Methodological Considerations
Paul, Elisabeth ULg

in Development in Practice (2005), 15(2), 134-150

This article identifies the need for an appropriate methodology for evaluating Fair Trade, given that most evaluations to date have been in-house or commissioned reviews and hence have not followed a ... [more ▼]

This article identifies the need for an appropriate methodology for evaluating Fair Trade, given that most evaluations to date have been in-house or commissioned reviews and hence have not followed a consistent approach. Focusing on the development aspects of Fair Trade, the article reviews a range of impact evaluation methods and presents a detailed methodology for analyzing Fair Trade. This methodology incorporates standard project evaluation criteria and is based on a wide range of proven methods for collecting and analysing data, principally qualitative but also quantitative. This framework is a modular package from which practitioners may select according to their needs and means, while still retaining an overarching logic. The article illustrates its use by reference to evaluations undertaken in Costa Rica, Ghana, Nicaragua, and Tanzania. The approach allows for a comprehensive understanding of Fair Trade programmes and enables these to be compared with conventional development projects. [less ▲]

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See detailEvaluation of false transrectal ultrasonographic pregnancy diagnoses in sheep by measuring the plasma level of pregnancy-associated glycoproteins
Karen, A.; Beckers, Jean-François ULg; Sulon, Joseph ULg et al

in Reproduction Nutrition Development (2003), 43(6, NOV-DEC), 577-586

The present study was undertaken to investigate to what extent pregnancy diagnoses made by transrectal ultrasonography could be confirmed by measurements of plasma concentration of ovine pregnancy ... [more ▼]

The present study was undertaken to investigate to what extent pregnancy diagnoses made by transrectal ultrasonography could be confirmed by measurements of plasma concentration of ovine pregnancy-associated glycoproteins (ovPAG). A total of 424 Awassi x Merino ewes were synchronized for estrus and examined by transrectal ultrasonography. In Experiment 1, the ewes (n = 156) were repeatedly scanned in a standing position on d 29, 36 and 50 of gestation. Similarly, the ewes (n = 268) in Experiment 2 were scanned on d 24, 29 and 34 of gestation, but these ewes were fasted for 12 h prior to the examination and the abdominal wall of each animal was lifted up by the hands of the assistant during the scanning. Blood samples were withdrawn after each transrectal ultrasonographic examination in both experiments. Ovine PAG concentrations were measured in plasma by a heterologous radioimmunoassay and the cut-off value for pregnancy was greater than or equal to 1 ng.mL(-1). Based on the lambing performance, in Experiment 1, altogether 47 false negative and 38 false positive diagnoses were made by transrectal ultrasonography in 24 and 33 ewes, respectively between d 29 and 50 of gestation. In Experiment 2, altogether 8 false negative and 13 false positive diagnoses both were made in 7 ewes between d 24 and 34 of gestation. In both experiments, all ewes with false negative diagnoses had ovPAG concentrations higher than the threshold level for pregnancy diagnosis and all ewes with false positive diagnoses had ovPAG concentrations lower than the threshold of pregnancy. Furthermore, by the PAG-RIA test all lambed or aborted ewes (n = 63) were correctly diagnosed as pregnant and with three exceptions, all non-lambed ewes (n = 361) were correctly diagnosed as non-pregnant during the examined periods of both experiments. [less ▲]

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See detailEvaluation of false ultrasonographic pregnancy diagnoses in cows by measuring plasma levels of bovine pregnancy-associated glycoprotein 1 (bPAG1).
Szenci, Otto; Taverne, M. A. M.; Beckers, Jean-François ULg et al

in Veterinary Record : Journal of the British Veterinary Association (1998), 142(2), 304-306

Between days 27 and 59 after artificial insemination (AI),189 ultrasonographic pregnancy diagnoses were made in 56 dairy cows using a 7·5 MHz linear-array rectal transducer. Blood samples were withdrawn ... [more ▼]

Between days 27 and 59 after artificial insemination (AI),189 ultrasonographic pregnancy diagnoses were made in 56 dairy cows using a 7·5 MHz linear-array rectal transducer. Blood samples were withdrawn from a jugular vein on the day of AI, on day 21, and after each ultrasonographic examination between days 27 and 31, days 34 and 38, days 41 and 45 and days 55 and 59 after AI. Plasma concentrations of bovine pregnancy-associated glycoprotein 1 (bPAG-1) were measured by radioimmunoassay. The results showed that before day 31, ultrasonographic scanning was not very sensitive because six of the 30 calving cows were incorrectly diagnosed as non-pregnant. In five of these animals, the uterus was located far cranial to the pelvic inlet. Five of the cows examined between days 27 and 31 were pregnant on the basis of plasma bPAG-1 levels on the same day, using 0·5 ng/ml as the cut-off point. Plasma levels of bPAG-1 and progesterone proved that four of the cows which had early positive ultrasonographic diagnoses but did not produce a calf, were pregnant when they were examined. [less ▲]

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