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See detailEffectiveness of bioremediation of crude oil contaminated subantarctic intertidal sediment: The microbial response
Delille, D.; Delille, Bruno ULg; Pelletier, E.

in Microbial Ecology (2002), 44(2), 118-126

A field study was initiated in February 1996 in a remote sandy beach of The Grande Terre (Kerguelen Archipelago, 69degrees 42' E, 49degrees 19' S) with the objective of determining the long-term effects ... [more ▼]

A field study was initiated in February 1996 in a remote sandy beach of The Grande Terre (Kerguelen Archipelago, 69degrees 42' E, 49degrees 19' S) with the objective of determining the long-term effects of some bioremediation agents on the biodegradation rate and the toxicity of oil residues under severe subantarctic conditions. A series of 10 experimental plots were settled firmly into sediment. Each plot received 2L of Arabian light crude oil and some of them were treated with bioremediation agents: slow release fertilizer Inipol EAP-22 (Elf Atochem) or fish composts. Plots were sampled on a regular basis over a 3-year period. A two-order of magnitude increase of saprophytic and hydrocarbon-utilizing microorganisms occurred during the first month of the experiment in all treated enclosures, but no clear differences appeared between the plots. Very high microbial populations were present during the experiment. Biodegradation within treated spots was faster than within the untreated ones and appeared almost complete after 6 months as indicated by the degradation index of aliphatic hydrocarbons within all plots. The analysis of interstitial water collected below the oily residues presented no toxicity. However, a high toxicity signal, using Microtox solid phase, appeared for all oiled sand samples with a noticeable reduction with time even if the toxicity signal remained present and strong after 311 days of oil exposition. As a conclusion, it is clear that the microbial response was rapid and efficient in spite of the severe weather conditions, and the rate of degradation was improved in presence of bioremediation agents. However, the remaining residues had a relatively high toxicity. [less ▲]

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See detailEffectiveness of biostimulation techniques for cleaning of diesel polluted subAntarctic soils (Crozet Archipelago)
Delille, D.; Pelletier, E.; Coulon, F. et al

in Alleman, B. C.; Keley, M. E. (Eds.) In situ bioremediation and on site bioremediation (2005)

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See detailEffectiveness of block copolymers as stabilizers for aqueous titanium dioxide dispersions of a high solid content
Creutz, Serge; Jérôme, Robert ULg

in Progress in Organic Coatings (2000), 40(1-4), 21-29

Copolymers of 2-(dimethylamino)ethyl methacrylate (DMAEMA) and sodium methacrylate (MANa) have been synthesized and tested as dispersants for the aqueous dispersion of titanium dioxide (80 wt.% solid ... [more ▼]

Copolymers of 2-(dimethylamino)ethyl methacrylate (DMAEMA) and sodium methacrylate (MANa) have been synthesized and tested as dispersants for the aqueous dispersion of titanium dioxide (80 wt.% solid). The molecular composition of the block copolymers has an effect on the dispersion stability. Triblock copolymers consisting of PMANa outer blocks are unable to stabilize the dispersion. Triblock copolymers of the reverse structure form poorly stable dispersions due to at least partial particle bridging. In the case of non-blocky distribution of the DMAEMA and MANa comonomers in the chains, the stabilization capability is lost. A decrease in the anchoring strength of the diblocks has a deleterious effect on the dispersion stability. Finally, the surface coverage depends on the availability of free copolymer chains (unimers) coexisting with micelles. These trends have been confirmed in a fully formulated paint containing Cu-phthalocyanine pigment. [less ▲]

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See detailEffectiveness of case management for maintaining frail older persons at home - intermediate results
Van Durme; Schmitz, Olivier; Cès, Sophie et al

Poster (2013, October)

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See detailEffectiveness of cell-adsorbed bacteriocin produced by Lactobacillus curvatus CWBI-B28 and selected essential oils to control Listeria monocytogenes in pork meat during cold storage.
Ghalfi, H.; Benkerroum, N.; Doguiet, D. D. K. et al

in Letters in applied microbiology (2007), 44(3),

Aims: To study the effectiveness of a combination of cell-adsorbed bacteriocin (CAB; a suspension of producer cells on which maximum bacteriocin has been immobilized by pH adjustments) of a Lactobacillus ... [more ▼]

Aims: To study the effectiveness of a combination of cell-adsorbed bacteriocin (CAB; a suspension of producer cells on which maximum bacteriocin has been immobilized by pH adjustments) of a Lactobacillus curvatus strain with oregano or savory essential oil to control Listeria monocytogenes in pork meat at 4 C. [less ▲]

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See detailThe effectiveness of combined oral lysine acetylsalicylate and metoclopramide compared with oral sumatriptan for migraine.
Tfelt-Hansen, P.; Henry, P.; Mulder, L. J. et al

in Lancet (1995), 346(8980), 923-6

Aspirin is commonly used to treat migraine attacks, although sumatriptan, a much more expensive treatment, is also effective. We compared a combination of lysine acetylsalicylate (equivalent to 900 mg ... [more ▼]

Aspirin is commonly used to treat migraine attacks, although sumatriptan, a much more expensive treatment, is also effective. We compared a combination of lysine acetylsalicylate (equivalent to 900 mg aspirin) and 10 mg metoclopramide (LAS+MTC) with oral sumatriptan (100 mg) and placebo in 421 patients with migraine. LAS+MTC was as effective as sumatriptan with a decrease of headache from severe or moderate to mild or none of 57% and 53%, respectively, for the first migraine attack treated. Both treatments were better than placebo (success rate 24%, p < 0.0001). LAS+MTC was significantly more effective in the treatment of nausea than sumatriptan (p < 0.0001) and was better tolerated (adverse events in 18% and 28%, respectively, p < 0.05). LAS+MTC is as effective as sumatriptan in the treatment of migraine attacks. It is also much cheaper. [less ▲]

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See detailEffectiveness of High Intensity Radial Shock Wave Therapy in The Treatment of Chronic Plantar Fasciitis
Demoulin, Christophe ULg; Vanderthommen, Marc ULg; Fromm, Aurélien et al

in European Journal of Physical and Rehabilitation Medicine (2016, April), 52(Suppl. 1 No. 2), 733

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain ... [more ▼]

Introduction: Literature is scarce concerning the effectiveness of high dose radial extracorporeal shock wave therapy (ESWT). Therefore, the aim of this study was to investigate its effectiveness on pain, function and pressure pain threshold in patients with chronicplantar fasciitis (PF). Materials and Methods: Patients with a diagnosis of chronic (pain lasting for more than 3 months) uni- or bilateral PF with a history of failed conservative treatment were included. After a 6-week control period during which no treatment occurred, a 2-week treatment period followed by a three weeks of rest (cicatrization phase) was provided. The treatment period consisted of three radial ESWT sessions (2000 impulses of 10 Hz frequency per session with an energy flux density of 0,275mJ/mm2) separated by a one-weekinterval. Patient assessments (pain intensity, foot function and pressure pain threshold (PPT) at the site of maximum local tenderness disability) were conducted at baseline, after the 6-week control phase (pre-treatment) and at the end of the cicatrization phase (post-treatment). Results: Thirty patients (19 women (63.3%)) with chronic PF and a mean age of 51.9±11 years were included in the present study. No drop-out occurred throughout the study period. No changes were observed at the pre-treatment assessment session except for pain intensity which decreased slightly but significantly (P<0.05). At the post-treatment session, highly significant (P<0.001) and clinically meaningful changes occurred for pain intensity (-34%), foot function score (-60%) and PPT (+68%). Conclusions: The present study suggests that high dose radial ESWT is a feasible and effective way to quickly and significantly decrease pain and disability in most patients with chronic PF. [less ▲]

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See detailEffectiveness of High Intensity Radial Shock Wave Therapy in The Treatment of Chronic Plantar Fasciitis
Demoulin, Christophe ULg; Vanderthommen, Marc ULg; Fromm, Aurélien et al

in Jacobs Journal of Physical Rehabilitation Medicine (2015), 1(3), 0117

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See detailEffectiveness of High-Dose Riboflavin in Migraine Prophylaxis. A Randomized Controlled Trial
Schoenen, Jean ULg; Jacquy, J.; Lenaerts, M.

in Neurology (1998), 50(2), 466-70

A deficit of mitochondrial energy metabolism may play a role in migraine pathogenesis. We found in a previous open study that high-dose riboflavin was effective in migraine prophylaxis. We now compared ... [more ▼]

A deficit of mitochondrial energy metabolism may play a role in migraine pathogenesis. We found in a previous open study that high-dose riboflavin was effective in migraine prophylaxis. We now compared riboflavin (400 mg) and placebo in 55 patients with migraine in a randomized trial of 3 months duration. Using an intention-to-treat analysis, riboflavin was superior to placebo in reducing attack frequency (p = 0.005) and headache days (p = 0.012). Regarding the latter, the proportion of patients who improved by at least 50%, i.e. "responders," was 15% for placebo and 59% for riboflavin (p = 0.002) and the number-needed-to-treat for effectiveness was 2.3. Three minor adverse events occurred, two in the riboflavin group (diarrhea and polyuria) and one in the placebo group (abdominal cramps). None was serious. Because of its high efficacy, excellent tolerability, and low cost, riboflavin is an interesting option for migraine prophylaxis and a candidate for a comparative trial with an established prophylactic drug. [less ▲]

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See detailThe effectiveness of inpatient geriatric evaluation and management units: a systematic review and meta-analysis.
Van Craen, Katleen; Braes, Tom; Wellens, Nathalie et al

in Journal of the American Geriatrics Society (2010), 58(1), 83-92

OBJECTIVES: To examine how geriatric evaluation and management units (GEMUs) are organized and to examine the effectiveness of admission on a GEMU. DESIGN: Systematic review and meta-analysis based on ... [more ▼]

OBJECTIVES: To examine how geriatric evaluation and management units (GEMUs) are organized and to examine the effectiveness of admission on a GEMU. DESIGN: Systematic review and meta-analysis based on literature search of multiple databases and the references lists of all identified articles and by contacting authors. SETTING: GEMUs. PARTICIPANTS: Elderly people admitted to a GEMU. MEASUREMENTS: Quality of the studies was assessed on 10 criteria. The outcome parameters were mortality, institutionalization, functional decline, readmission, and length of stay at different follow-up points. A random-effects meta-analysis was performed using Hedges' gu and variance of relative risk (RR). RESULTS: GEMUs are organized in a heterogeneous way and the included studies gave no thorough description of comprehensive geriatric assessment (CGA). Involvement of a multidisciplinary team was a key element in all GEMUs. The individual trials showed that admission to a GEMU has one or more favorable effects on the outcomes of interest, with two significant effects in the meta-analysis: less functional decline at discharge from the GEMU (RR=0.87, 95% confidence interval (CI)=0.77-0.99; P=.04) and a lower rate of institutionalization 1 year after discharge (RR=0.78, CI=0.66-0.92; P=.003). For the other outcomes in the meta-analysis, a GEMU did not induce significantly different outcomes than usual care. CONCLUSION: This meta-analysis shows a significant effect in favor of the GEMU group on functional decline at discharge and on institutionalization after 1 year. There is heterogeneity between the studies, poor quality of some randomized controlled trials, and shortage of information about CGA. Multidisciplinary CGA offered in a GEMU may add value to the care for frail older persons admitted to the hospital, but the limitations confirm the need for well-designed studies using explicit CGA and more-structured and -coherent assessment instruments such as the Minimum Data Set Resident Assessment Instrument. [less ▲]

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See detailEffectiveness of Moringa oleifera defatted cake versus seed in the treatment of unsafe drinking water : case study of surface and well waters in Burkina Faso.
Kabore, Aminata; Savadogo, Boubacar; Rosillon, Francis ULg et al

in Journal of Water Resource and Protection (2013), 5(11),

Safe drinking water access for rural populations in developing countries remains a challenge for a sustainable develop-ment, particularly in rural and periurban areas of Burkina Faso. The study aims to ... [more ▼]

Safe drinking water access for rural populations in developing countries remains a challenge for a sustainable develop-ment, particularly in rural and periurban areas of Burkina Faso. The study aims to investigate the purifying capacity of Moringa oleifera defatted cake as compared to Moringa oleifera seed in the treatment of surface and well waters used for populations alimentation. A total of 90 water samples were collected in sterile glass bottles from 3 dams’ water reservoirs, a river, and a large diameter well, respectively. The water samples were treated in triplicate with Moringa oleifera seed and defatted cake coagulants. At different settling time and coagulant concentration, turbidity and pH were measured to determine the optimal conditions and factors influencing treatment with regard to sampling source. Nine physicochemical parameters (turbidity, pH, nitrates, nitrites, calcium, magnesium, total hardness, organic matter and sulfates), three bacterial fecal pollution indicators (Escherichia coli, fecal Coliforms and fecal Streptococcus) and parasite cysts were monitored based on laboratory standard methods. Data were analyzed using the Student’ t test and XLSTAT 7.5.2 statistical software. From the results obtained, for the same concentration of coagulant, settling times providing the lowest turbidity were significantly shorter (p<0.0001) with Moringa oleifera cake than seed. Optimum settling time with Moringa oleifera cake was between 15-60 min versus 60-120 min, with Moringa oleifera seed. Both treatments reduced significantly minerals concentration in water excepted sulfates for which the concentration reversely increased. However, only Moringa oleifera cake treatment reduced organic matter content in all the water samples, while it increased with Moringa oleifera seed one (p<0.0001). The reduction of microbial pollution indicators was 92-100% with M. oleifera cake treatment and 84-100% with M. oleifera seed one. Overall, for all water samples, Moringa oleifera cake treatment appeared more efficient in improving drinking water quality than the M. oleifera seed treatment. [less ▲]

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See detailThe effectiveness of oil bioremediation processes in marine sediments under sub-Antarctic conditions
Pelletier; Delille, Bruno ULg; Delille, D.

Conference (2001, September)

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See detailEffectiveness of pharmaceutical care for patients with COPD (PHARMACOP) : A randomized controlled trial
Tommelein, E; Mehuys, E; Van Hees, Thierry ULg et al

Conference (2012, September)

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See detailEffectiveness of PHARMAceutical care for patients with COPD (PHARMACOP): a randomized controlled trial
Tommelein, Eline; Mehuys, Els; Van Hees, Thierry ULg et al

in British Journal of Clinical Pharmacology (2014), 77(5), 756-766

AIM: Few well-designed randomized controlled trials (RCT) regarding the impact of community pharmacist interventions on pharmacotherapeutic monitoring of patients with Chronic Obstructive Pulmonary ... [more ▼]

AIM: Few well-designed randomized controlled trials (RCT) regarding the impact of community pharmacist interventions on pharmacotherapeutic monitoring of patients with Chronic Obstructive Pulmonary Disease (COPD) have been conducted. We assessed the effectiveness of a pharmaceutical care program for patients with COPD. METHODS: The PHARMACOP-trial is a single-blind 3-month RCT, conducted in 170 community pharmacies in Belgium, enrolling patients prescribed daily COPD medication, aged >/=50 years, and with a smoking history >/=10 pack-years. A computer-generated randomization sequence allocated patients to intervention (n=371), receiving protocol-defined pharmacist care, or control group (n=363), receiving usual pharmacist care (1:1 ratio, stratified by center). Interventions, focusing on inhalation technique and adherence to maintenance therapy, were carried out at start of the trial and at one month follow-up. Primary outcomes were inhalation technique and medication adherence. Secondary outcomes were exacerbation rate, dyspnea, COPD specific and generic health status and smoking behavior. RESULTS: From December 2010 to April 2011, 734 patients were enrolled. 42 patients (5.7%) were lost to follow-up. At the end of the trial, inhalation score (Mean estimated difference [Delta],13.5%; 95% Confidence Interval [CI], 10.8-16.1; P<.0001) and medication adherence (Delta, 8.51%; 95%CI, 4.63-12.4; P<.0001) were significantly higher in the intervention group compared to the control group. In the intervention group, a significantly lower hospitalization rate was observed (9 vs 35; Rate Ratio, 0.28; 95%CI, 0.12-0.64; P=.003). No other significant between-group differences were observed. CONCLUSION: Pragmatic pharmacist care programs improve the pharmacotherapeutic regime in patients with COPD and could reduce hospitalization rates. [less ▲]

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See detailEffectiveness of poly(vinylpyridine) block copolymers as stabilizers of aqueous titanium dioxide dispersions of a high solid content
Creutz, Serge; Jérôme, Robert ULg

in Langmuir (1999), 15(21), 7145-7156

Diblock copolymers of 4-vinylpyridine (4VP) and sodium methacrylate (MANa) have been synthesized and tested as dispersants for aqueous dispersions (80 wt % solid) of alumina-coated titanium dioxide. P4VP ... [more ▼]

Diblock copolymers of 4-vinylpyridine (4VP) and sodium methacrylate (MANa) have been synthesized and tested as dispersants for aqueous dispersions (80 wt % solid) of alumina-coated titanium dioxide. P4VP is strongly anchored onto the pigment surface. The molecular composition of the block copolymers has an effect on the amount of copolymer required for imparting good stability to the slurry. Where the two parent triblock copolymers are concerned, triblocks consisting of PMANa outer blocks have a stabilizing efficiency comparable to the diblock copolymers, whereas the reverse structure is much less efficient. In the case of a nonblock distribution of 4VP and MANa in the copolymer chains, the stabilization effect is lost. Finally, the comparison of different stabilizing blocks attached to the same anchoring block confirms that the electrosteric stabilization mechanism is superior to the steric stabilization mechanism. A decrease in the anchoring strength of the diblocks has a deleterious effect on the dispersion stability. [less ▲]

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