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See detailEvaluation of plasma carboxy-terminal cross-linking telopeptide of type I collagen concentration in horses.
Carstanjen, Bianca; Hoyle, Nicholas R; Gabriel, Annick ULg et al

in American Journal of Veterinary Research (2004), 65(1), 104-9

OBJECTIVE: To evaluate a human assay for quantification of carboxy-terminal cross-linking telopeptide of type I collagen (CTX-I), assess the influence of age on plasma CTX-I concentration, investigate the ... [more ▼]

OBJECTIVE: To evaluate a human assay for quantification of carboxy-terminal cross-linking telopeptide of type I collagen (CTX-I), assess the influence of age on plasma CTX-I concentration, investigate the relationship between plasma CTX-I and serum osteocalcin concentrations, and determine whether concentrations of plasma CTX-I or serum osteocalcin fluctuate in circadian manner in horses. HORSES: 75 clinically normal horses. PROCEDURE: Cross-reactivity between equine serum CTX-I and CTX-I antibodies in an automated electrochemiluminescent sandwich antibody assay (ECLIA) was evaluated via a specificity test (ie, dilution test) and recovery calculation. Serum osteocalcin concentration was measured with an equine-specific osteocalcin radioimmunoassay. To analyze diurnal variations in plasma CTX-I and serum osteocalcin concentrations, blood samples were obtained hourly during a 24-hour period. RESULTS: Results of the dilution test indicated good correlation (r > 0.99) between expected serum CTX-I concentrations and measured serum CTX-I concentrations. The calculated CTX-I recovery was 97.6% to 109.9%. Plasma CTX-I and serum osteocalcin concentrations were correlated. Plasma CTX-I concentration was inversely correlated with age of the horse. No significant circadian variations in plasma CTX-I and serum osteocalcin concentrations were detected. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that the fully automated CTX-I ECLIA can be used for evaluation of plasma and serum samples from horses and may be a useful tool to monitor bone metabolism changes. Horses in this study did not have notable diurnal fluctuations in serum osteocalcin and plasma CTX-I concentrations. [less ▲]

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See detailEvaluation of pleural disease with 18-fluorodeoxyglucose positron emission tomography imaging
Duysinx, Bernard ULg; Nguyen, Delphine; Louis, Renaud ULg et al

in CHEST (2004), 125(2), 489-493

STUDY OBJECTIVES: To study the ability of positron emission tomography (PET) using 18-fluorodeoxyglucose (FDG) to distinguish between benign and malignant disease in exudative pleural effusions and ... [more ▼]

STUDY OBJECTIVES: To study the ability of positron emission tomography (PET) using 18-fluorodeoxyglucose (FDG) to distinguish between benign and malignant disease in exudative pleural effusions and pleural thickening. DESIGN: Prospective study of 98 consecutive patients presenting with either pleural thickening or an exudative pleural effusion. SETTING: Department of pulmonary medicine of a university hospital. METHODS: FDG-PET was performed on each subject before invasive procedures were used to determine the etiologic diagnosis. FDG-PET data were analyzed by visual interpretation. RESULTS: Sixty-three of 98 patients were found to have malignant pleural disease after histologic analysis. Sixty-one of 63 patients with histologically confirmed malignant disease showed FDG uptake within the area of pleural thickening. Uptake was graded as intense in 51 cases and moderate in 10 cases. Only two patients with malignant pleural disease did not show increased FDG uptake. FDG-PET imaging showed an absence of FDG uptake, and correctly classified 31 of 35 benign lesions. For the remaining four lesions, intense FDG uptake was seen in one case of parapneumonic effusion, while moderate and localized uptake was observed in one parapneumonic, one tuberculous, and one uremic pleurisy. The sensitivity of the method to identify malignancy was 96.8% with a negative predictive value of 93.9%, while its specificity was 88.5% and its positive predictive value was 93.8%. CONCLUSIONS: Our results suggest that FDG-PET is an effective tool for differentiating between benign and malignant pleural diseases. [less ▲]

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See detailEvaluation of pleural diseases with FDG-PET imaging: preliminary report.
Bury, Thierry ULg; Paulus, P; Dowlati, A et al

in Thorax (1997), 52(2), 187-9

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis ... [more ▼]

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis of pleural disease was investigated in 25 patients. METHODS: PET was performed on each subject before invasive procedures were used to determine the aetiological diagnosis. The PET data were analysed by visual interpretation of coronal, sagittal, and transverse slices. RESULTS: Sixteen patients were found to have malignant pleural disease and nine had benign disease. All patients with histologically confirmed malignant disease showed FDG uptake within the pleural thickening which was intense in 14 cases and moderate in two. PET imaging showed the absence of FDG uptake and correctly categorised seven non-malignant lesions. Two patients with infectious pleural diseases showed a localised and moderate FDG uptake. CONCLUSION: Our preliminary results suggest that FDG-PET could be an effective tool for differentiating between benign and malignant pleural diseases. [less ▲]

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See detailEvaluation of plyometric training on functional performances and isokinetic strength
Lehance, Cédric ULg; Croisier, Jean-Louis ULg; Maquet, Didier ULg et al

in Isokinetics & Exercise Science (2004, March), 12(1), 79-80

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See detailEvaluation of population density of Pichia anomala strain K and Candida oleophila strain O and their protection against Penicillium expansum Link on apples.
Lahlali, Rachid; Jijakli, Haissam ULg

in Bulletin OILB/SROP = IOBC/WPRS Bulletin (2004), 27(8), 341-346

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See detailEvaluation of power line cable fatigue parameters based on measurements on a laboratory cable test span
Guérard, Suzanne ULg; van dyke, Pierre; Lilien, Jean-Louis ULg

in Lilien, Jean-Louis (Ed.) EIght International symposium on Cable Dynamics, ISCD 2009 (2009)

The present paper describes experiments carried out on IREQ laboratory cable test bench. Test span arrangement is a 63.15m cable span with termination ends designed so as to minimize energy dissipation. A ... [more ▼]

The present paper describes experiments carried out on IREQ laboratory cable test bench. Test span arrangement is a 63.15m cable span with termination ends designed so as to minimize energy dissipation. A shaker provides a vertical alternating force to the conductor. During the experiments, a maximum of information on mode shape is collected: location of nodes, antinode amplitude of vibration, relative displacement at 44.5, 89, and 178mm from the last point of contact with the metallic clamp. Several configurations are studied: span equipped with an homogeneous steel cable, span equipped with an ACSR Crow conductor, sometimes in combination with other equipments such as a vibration damper or a local mass, to investigate how the presence of such devices impacts conductor vibrations. It results from these experiments an interesting comparison of two widely used fatigue indicators, the relative displacement Yb 2 (also called “bending amplitude”) and fymax (the product of antinode amplitude of vibration by frequency). Also, collected data gives indirect information on conductor variable bending stiffness. [less ▲]

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See detailEvaluation of preoperative use of danazol, gestrinone, lynestrenol, buserelin spray and buserelin implant, in the treatment of endometriosis associated infertility.
Donnez, Jacques; NISOLLE, Michelle ULg; Clerckx, Françoise et al

in Progress in Clinical & Biological Research (1990), 323

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See detailEvaluation of prevalence of osteoporosis and osteopenia in men presenting at multiple risk detection campaign
Hanssens, L. C.; De Ceulaer, F.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2004, May), 15(Suppl.1), 54

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See detailEvaluation of prevalence of osteoporosis and osteopenia in men presenting at multiple risk detection campaign
Hanssens, L.; De Ceulaer, F.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 90

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See detailEvaluation of primary brain tumors with F-TYR and FDG PET : correlation with pathology and survival.
LOVINFOSSE, Pierre ULg; BORN, J.; MARTIN, Didier ULg et al

in Journal of Nuclear Medicine (The) (2008), 49(SUPPL), 77

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See detailEvaluation of process-driven spray retention model on ear-ly growth stage barley
Massinon, Mathieu ULg; Ouled Taleb Salah, Sofiene ULg; De Cock, Nicolas ULg et al

Conference (2014, July)

The efficiency of spray application of foliar plant protection products with hydraulic nozzles on vertically oriented and hydrophobic plants at early growth stages can be very low. The spray retention by ... [more ▼]

The efficiency of spray application of foliar plant protection products with hydraulic nozzles on vertically oriented and hydrophobic plants at early growth stages can be very low. The spray retention by crop leaves is affected by application parameters resulting from nozzle kind, size and operating pressure as well as spray mixture physicochemical properties. When optimizing the spray application, such targets are often used to perform retention trials for comparative purpose, i.e. indoor grown monocotyledonous at two leaves stage. A typical arrangement consists in spraying few plants sufficiently spaced underneath the nozzle to avoid interference due to secondary droplets from impacts on other plants. However, retention trials turn out to ineffective for significantly discriminating between application methods and mixtures due to the high variability between trials resulting from the different droplets retained by each plant. An alternative to retention trials is to tackle spray retention with a physical approach at the droplet scale. Such tests are often performed using high speed imaging with high magnification optics to characterize droplet impacts; adhesion, rebound or shatter on small excised leaf areas and neglect, however, the overall plant architecture. The aim of this paper is to evaluate a droplet interception model connecting actual spray retention with process-driven retention models. In this study, barley plants (BBCH11) were sprayed with 2 formulations using the same nozzle. The actual spray retention was assessed by dosing a fluorescent tracer added to the sprayed mixture. The plants were placed linearly below the center of a single moving nozzle during sprayings. Each plant was reconstructed in 3D afterwards using a structured light 3D scanner and used as input for the model. A virtual nozzle was built on the base of droplet size distributions measured with high speed shadow imaging by performing an adjustment of the distribution by the method of moments. A ran-dom droplet distribution was allocated for each spraying of a barley plant. Droplet velocities were given to droplets on the basis of the droplet velocity – diameter correlation by resolving the droplet transport equations for different droplet sizes. Initial droplet positions were ran-domly given. The interception model is based on a mathematical formalism for the intercep-tion between triangles of the 3D plant and droplet directions. If the droplet impacts a leaf, the amount actually retained by the leaf was computed on the basis of the droplet impact energy and impact behavior from experiments with high speed shadow imaging. In conclusion, the interception model allowed determining the spray retention by plants and discriminating ap-plication parameters by explaining the variability resulting from various droplet size distribu-tions intercepted by single plant. [less ▲]

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See detailEvaluation of proposals of Belgian Social Security Institute for reimbursement of bone densitometry tests. Toward a cost-effective strategy for osteoporosis screening?
Ben Sedrine, Wafa ULg; Ethgen, Olivier ULg; Devogelaer, Jean-Pierre et al

in Aging Clinical & Experimental Research (2004), 16(5), 413-419

BACKGROUND AND AIMS: The Belgian Social Security Institute (hereafter INAMI) proposes a list of conditions to be considered as a prerequisite for reimbursement of Bone Mineral Density (BMD) measurements ... [more ▼]

BACKGROUND AND AIMS: The Belgian Social Security Institute (hereafter INAMI) proposes a list of conditions to be considered as a prerequisite for reimbursement of Bone Mineral Density (BMD) measurements. The aim of this paper was to evaluate the diagnostic accuracy of the proposed criteria for identifying osteoporosis, and to gauge how useful they are for more rational application of densitometry tests. METHODS: 3748 Caucasian women aged at least 50 years old were recruited consecutively from an outpatient university center, from the database of which all relevant data corresponding to the INAMI list of clinical factors, as well as patients' age, weight and height, were collected. BMD measurements using dual X-ray absorptiometry were reported at the spine and hip regions. Diagnostic accuracy was evaluated through measures of sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). Additionally, from ROC analysis, benchmark values for age and body mass index were identified and then, used alone and in combination with the INAMI test, were applied to define various screening strategies. For each of them, associated costs per osteoporotic patient detected were estimated. Cost estimates refer only to the costs associated with the densitometric procedure from the perspective of the reimbursement health authorities. RESULTS: Applying INAMI criteria for detecting osteoporosis at any of the considered sites yielded sensitivity of 68.9%, specificity of 50.7%, PPV of 42.9% and NPV of 57.3%. Comparison of incremental costs per patient of the different strategies revealed that, with 67.1 Euros, the option of opening BMD coverage to women on the basis of the INAMI conditions would be more cost-effective than mass screening (90.1 Euros) or applying the age criterion alone (70.2 Euros). However, the BMI condition seems to act as a better indicator of risk than the INAMI criteria in those meeting the age condition (35.4 Euros). CONCLUSIONS: The accuracy of the INAMI proposal turns out to be quite unsatisfactory, and did not adequately cover the population at risk of osteoporosis. From a resource allocation perspective, the best strategy by far would be to recommend using concomitantly INAMI, age and BMI-selective criteria. Some adaptations could enhance the usefulness of the INAMI proposals as a selective approach for BMD referral and reimbursement. [less ▲]

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See detailEvaluation of pyridinic sulfonamides related to nimesulide as COX-2 selective inhibitors
Julemont, F.; De Leval, X.; Neven, P. et al

Poster (2002, March 02)

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See detailEvaluation of pyridinic sulfonamides related to nimesulide as COX-2 selective inhibitors
Julemont, F.; De Leval, X.; Neven, P. et al

in Fundamental & Clinical Pharmacology (2002)

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See detailEvaluation of pyridinic sulfonamides related to nimesulide as COX-2 selective inhibitors
Julémont, F.; De Leval, X.; Neven, P. et al

in Fundamental & Clinical Pharmacology (2002)

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See detailEvaluation of realtime spray drift using RTDrift Gaussian advection-diffusion model
Lebeau, Frédéric ULg; Verstraete, Arnaud ULg; Schiffers, Bruno ULg et al

in Spanoghe, Pieter (Ed.) COMMUNICATIONS IN AGRICULTURAL AND APPLIED BIOLOGICAL SCIENCES (2009, May 19)

A spray drift model was developed to deliver real time information to the pesticide applicator. The sprayer is equipped with sensors to deliver real time measurement of operational parameters as spray ... [more ▼]

A spray drift model was developed to deliver real time information to the pesticide applicator. The sprayer is equipped with sensors to deliver real time measurement of operational parameters as spray pressure, boom height, horizontal boom movements and geolocalization. The spray droplet size spectrum as a function of pressure was characterized using PDI measurements. Wind speed and direction were measured using a sprayer mounted 2-D ultrasonic anemometer. For each successive boom position, a diffusion-advection Gaussian tilting plume model is used to compute the spray drift deposits downwind. Drift is computed independently for each droplet classes and each nozzle based on the operating parameters. Field trials were performed on a test plot in various wind conditions. The ground drift was measured for different drift distances using fluorimetry analysis. Results show that drift deposits are mainly affected by wind speed and direction what was correctly accounted for by the model. Short distance drift deposits values were overestimated by the model while long distance drift was underestimated. It appears that this most probably origins from embarked wind speed measurements and diffusion parameter. It is concluded that a treatment of embarked wind speed and diffusion measurement should be used to minimize these errors. [less ▲]

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See detailEvaluation of respiratory function by barometric whole-body plethysmography in healthy dogs
Talavera, J.; Kirschvink, N.; Schuller, S. et al

in Veterinary Journal (2006), 172(1), 67-77

The objective of the present study was to assess the validity of barometric whole-body plethysmography (BWBP), to establish reference values, and to standardise a bronchoprovocative test to investigate ... [more ▼]

The objective of the present study was to assess the validity of barometric whole-body plethysmography (BWBP), to establish reference values, and to standardise a bronchoprovocative test to investigate airway responsiveness using BWBP in healthy dogs. BWBP measurements were obtained from six healthy beagle dogs using different protocols: (1) during three consecutive periods (3.5 min each) in two morning and two evening sessions; (2) before and after administration of two protocols of sedation; (3) before and after nebulisation of saline and increasing concentrations of carbachol and histamine both in conscious dogs and in dogs under both protocols of sedation. Enhanced pause (PENH) was used as index of bronchoconstriction. Basal BWBP measurements were also obtained in 22 healthy dogs of different breeds, age and weight. No significant influence of either time spent in the chamber or daytime was found for most respiratory variables but a significant dog effect was detected for most variables. A significant body weight effect was found on tidal volume and peak flow values (P < 0.05). Response to carbachol was not reproducible and always associated with side effects. Nebulisation of histamine induced a significant increase in respiratory rate, peak expiratory flow, peak expiratory flow/peak inspiratory flow ratio and PENH (P < 0.05). The response was reproduced in each dog at different concentrations of histamine. Sedation with acepromazine + buprenorphine had little influence on basal measurements and did not change the results of histamine challenge. It was concluded that BWBP is a safe, non invasive and reliable technique of investigation of lung function in dogs which provides new opportunities to characterise respiratory status, to evaluate airway hyperresponsiveness and to assess therapeutic interventions. (c) 2005 Elsevier Ltd. All rights reserved. [less ▲]

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