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See detailThe effects of cognitive remediation therapy on AM deficits in schizophrenia patients
Boulanger, Marie ULg; Collet, Denis; Cornet, Lidvine et al

Poster (2008)

Schizophrenia is accompanied by deficit in autobiographical memories (AM). These impairments are correlated to difficulties in imagining specific events that might happen to them in the future ... [more ▼]

Schizophrenia is accompanied by deficit in autobiographical memories (AM). These impairments are correlated to difficulties in imagining specific events that might happen to them in the future (D’Argembeau, Raffard et Van-der-Linden, 2008). Previous study suggested that the specific autobiographical memory (past and future) may be improved by an AM remediation therapy (Blairy et al., accepted). The aim of the present study was to compare performances from individuals involved in an AM remediation intervention to individuals involved in the cognitive remediation therapy program from Brenner (IPT) (Pomini, Neis, Brenner, Hodel et Roder, 1998). The results showed that the participants tend to recall more specific events after therapies, confounded pass and future events (t(7) = 3.28 ; p = .013). These results would be promising for future research. [less ▲]

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See detailEffects of cold and warm ischemia on the mitochondrial oxidative phosphorylation of swine lung.
Willet, Katty; Detry, Olivier ULg; Lambermont, Bernard ULg et al

in Transplantation (2000), 69(4), 582-588

BACKGROUND: The aim of the study was to investigate the consequence of warm and cold ischemia on lung mitochondria in order to define bioenergetic limits within lung could be suitable for pulmonary ... [more ▼]

BACKGROUND: The aim of the study was to investigate the consequence of warm and cold ischemia on lung mitochondria in order to define bioenergetic limits within lung could be suitable for pulmonary transplantation. METHODS: Twenty-two pigs underwent lung harvesting after lung flush with Euro-Collins solution. Mitochondria were isolated from fresh lungs, from lungs submitted to 24 or 48 hr of cold ischemia, to 30 or 45 min of warm ischemia, and to 30 min of warm ischemia followed by 24 or 48 hr of cold ischemia. Mitochondrial oxidative phosphorylation parameters were determined in isolated mitochondria by in vitro measurement of oxygen consumption. RESULTS: Relative to controls, mitochondria submitted to cold ischemia showed an alteration in the oxidoreductase activities of the respiratory chain but no membrane permeability alteration. After 48 hr of cold ischemia, there was a decrease in the yield of the oxidative phosphorylation. Thirty minutes of warm ischemia did not alter the mitochondrial respiratory parameters. However, lung submitted to 45 min of warm ischemia showed mitochondrial damage as a decrease in the oxidative phosphorylation efficiency and ADP availability but no change in the oxidoreductase activities. Relative to cold ischemia alone, 30 min of warm ischemia preceding cold ischemia promoted no significant change in the respiratory parameters. CONCLUSIONS: On bioenergetic basis, lung submitted to warm ischemia could be suitable for transplantation if the warm ischemia duration does not exceed 30 min. This could be a major concern in lung procurement from non-heart beating donors. [less ▲]

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See detailEffects of cold temperatures on the early stages of maize inbreds
Riva-Roveda, Laetitia ULg; Escale, Brigitte; Giauffret, Catherine et al

Poster (2012, July)

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See detailEffects of Collective Fluctuations in 2D-ELDOR spectroscopy
Fresch, Barbara ULg; Moro, Giorgio J.

Poster (2006)

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See detailEffects of colloïdal gold either free or incorporated into liposomes on human synovial cells in culture
Lhoets-Gautier, Marie -Paule; De Pauw-Gillet, Marie-Claire ULg; Van Ophem P et al

in Biology of the Cell (1982, July), 45(1), 3

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See detailEffects Of Commercial Fatty-Acids On Cutinase Release By Ascochyta-Pisi
Nasraoui, B.; Lepoivre, Philippe ULg; Semal, J.

in Journal of Phytopathology-Phytopathologische Zeitschrift (1992), 136(3),

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See detailEffects of compensatory growth on animal performance and plasma metabolites in growing fattening bulls
Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg; Clinquart, Antoine ULg et al

in Proceedings of the 44th Annual Meeting of E.A.A.P. (1993)

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See detailEffects of compression on human subchondral osteoblast metabolism
Kesteloot, Frédéric ULg; Gabay, Odile; Msika, Philippe et al

Poster (2009, May 24)

Introduction. Recent data showed that subchondral bone plays an important role in osteoarthritis (OA). Metabolic and morphologic modifications in this tissue contribute to the degradation of the ... [more ▼]

Introduction. Recent data showed that subchondral bone plays an important role in osteoarthritis (OA). Metabolic and morphologic modifications in this tissue contribute to the degradation of the overlaying cartilage. It was suggested that abnormal mechanical pressure exerted onto the articulation was responsible to these changes. Here, we evaluated the effects of compression on osteoblasts from subchondral bone. Method. Osteoblasts were isolated from sclerotic (SC) or non-sclerotic (NSC) areas of human OA subchondral bone. After 28 days, osteoblasts were surrounded by their matrix. This osteoblasts-containing membrane was then placed onto a Biopress Flexercell plate and submitted to a 4h 1.67 MPa compression (1 Hz). Expression of IL-6, IL-8, COX-2, VEGF, IGF-1, OPG and RANKL was evaluated by RT-PCR. IL-6, IL-8 and PGE2 were quantified by ELISA. Results. Basal IL-6, VEGF, COX-2, IGF-1 and RANKL mRNA levels were significantly increased in SC osteoblasts as compared to NSC. By contrast, SC osteoblasts expressed less OPG than those from NSC areas. Compressions induced the expression of genes coding for IL-6, IL-8, COX-2, IGF-1, VEGF and RANKL but decreased the expression of OPG in NSC osteoblasts (p<0.01). Interestingly, compressed NSC osteoblasts expressed similar levels of these genes than SC osteoblasts. Conclusions. We show that our model of compression can induce in NSC osteoblasts a phenotype similar to this observed in sclerotic areas. Moreover, SC osteoblasts are less sensitive to mechanical stimuli than NSC osteoblasts. These results clarify the role of compression in the pathogenesis of subchondral bone sclerosis and allow new perspectives of research in this field. [less ▲]

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See detailEffects of concentrate level on milk production and traffic of grazing cows milked by a mobile automatic milking system on pasture
Lessire, Françoise ULg; Hornick, Jean-Luc ULg; Dufrasne, Isabelle ULg

in Hopkins, Alan; Collins, Rosemary; Fraser, Marieacia (Eds.) et al EGF at 50: The future of European Grasslands (2014, September 10)

Cows milked by an automatic milking system in pastures were assigned in 2 groups receiving different amounts of concentrates (2.1 kg vs 4.1 kg). The effect of concentrates’ level on milk yield (MY) and ... [more ▼]

Cows milked by an automatic milking system in pastures were assigned in 2 groups receiving different amounts of concentrates (2.1 kg vs 4.1 kg). The effect of concentrates’ level on milk yield (MY) and returns to the robot was assessed. Concentrates’ level had a positive influence on daily milk production over the grazing period as cows of low concentrates group produced 21.43 ± 0.62 kg compared with 24.33 ± 0.62 kg in high concentrates group. However this effect was modulated subsequently to grass quality and availability. Regarding daily voluntary returns to the robot, high concentrates group showed higher frequency (3.66 ± 0.05, compared with 3.22 ± 0.04 in low concentrates group) demonstrating positive impact of complement distribution on cows’ traffic. [less ▲]

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See detailEffects of consolidation of procedural motor memory traces on slow and fast spindles
Barakat, M; Doyon, J; Debas, K et al

Poster (2009, April)

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See detailEffects of constitutively active GTPases on fibroblast behavior.
Zhang, Z.-G.; Lambert, Charles ULg; Servotte, S. et al

in Cellular and Molecular Life Sciences : CMLS (2006), 63(1), 82-91

The GTP-binding proteins RhoA, Cdc42 and Rac1 regulate the organization and turnover of the cytoskeleton and cell-matrix adhesions, structures bridging cells to their support, and translating forces ... [more ▼]

The GTP-binding proteins RhoA, Cdc42 and Rac1 regulate the organization and turnover of the cytoskeleton and cell-matrix adhesions, structures bridging cells to their support, and translating forces, external or generated within the cell. To investigate the specific requirements of Rho GTPases for biomechanical activities of clonal cell populations, we compared side-by-side stable lines of human fibroblasts expressing constitutively active (CA) RhoA, Cdc42 or Rac1. There was no marked effect of any CA GTPase on cell adhesion to different extracellular matrix proteins. Cell spreading was CA Rho GTPase specific and independent of the extracellular matrix proteins allowing adhesion. Mechanical properties were dramatically restricted by CA RhoA on bi- and in tri-dimensional surroundings, were boosted by CA Rac1 on bi-dimensional surroundings only, and were not or marginally affected by CA Cdc42. In conclusion, the action of Rho GTPases appears to depend on the task cells are performing. [less ▲]

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See detailEffects of copper sulfate given alone or with alpha-MSH and L-tyrosine on B16 melanoma cells cultured in serum-free media.
De Pauw-Gillet, Marie-Claire ULg; wang, François; Simonon, A. et al

in Archives of Biology (1987), 98(3), 327-39

This study shows that copper sulphate (0.1mM) has antiproliferative effects in B16 melanoma cells cutured in various serum-free media.

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See detailEffects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1)
Mouithys-Mickalad, Ange ULg; Deby, Ginette ULg; Dogné, Jean-Michel ULg et al

in Biochemical and Biophysical Research Communications (2004), 325(4), 1122-1130

Chronic inflammation through foam cells and macrophages is important in atherosclerosis development, and can be considered as therapeutic targets. Cyclooxygenase and NADPH-oxidase were expressed within ... [more ▼]

Chronic inflammation through foam cells and macrophages is important in atherosclerosis development, and can be considered as therapeutic targets. Cyclooxygenase and NADPH-oxidase were expressed within atherosclerotic lesions. Reactive oxygen species produced by NADPH oxidase were found to trigger the cyclooxygenase-2 expression. The effects of preferential COX-2 inhibitors on ROS produced by Chlamydia-primed human monocytes (THP-1 cells) were evaluated by fluorescence, chemiluminescence, oxymetry, and EPR spin trapping. Fluorescence assays showed an increased production of ROS with Chlamydia versus cells primed by 10(-8) M PMA. COX-2 inhibitors inhibited in a dose-dependent manner the luminol-enhanced CL while ibuprofen and diclofenac increased the chemiluminescence response. By EPR spin trapping, COX-2 inhibitors, ibuprofen, and diclofenac, exhibited a dose-dependent inhibiting effect (10 and 100 muM) on the EPR signal appearance. Our cell model combining EPR, chemiluminescence, and oxymetry appeared relevant to study the modulating effects of preferential COX-2 inhibitors on the cell oxidant activity and chronic inflammatory diseases. (C) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailEffects of cromakalim analogues on rat pancreatic B-cells, rat aorta rings and rat uterus. Study of their mechanism of action as potassium channel activators
Sebille, S.; Boverie, S.; Becker, B. et al

Poster (2003, November 22)

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See detailEffects of cromakalim analogues on rat pancreatic B-cells, rat aorta rings and rat uterus. Study of their mechanism of action as potassium channel activators
Sebille, S.; Boverie, S.; Becker, B. et al

in Fundamental & Clinical Pharmacology (2004)

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See detailEffects of crops on solute transport in undisturbed soil
Garré, Sarah ULg; Javaux, Mathieu; Vanderborght, Jan

Poster (2009)

Models predicting movement of surface applied chemicals incorporate knowledge on the water velocity field and moisture content distribution. Although the influence of root water uptake on solute transport ... [more ▼]

Models predicting movement of surface applied chemicals incorporate knowledge on the water velocity field and moisture content distribution. Although the influence of root water uptake on solute transport is commonly recognized as important, it has been studied sparsely. Yet, plants may take up a large part of the infiltrating water, thereby influencing the water flow pattern in the soil and concurrently solute transport processes. For this reason, experiments are required to investigate the relationship between plant root water uptake and flow field variability. The role of root water uptake on solute transport will be elucidated in two undisturbed soil columns. During three consecutive experiments, the influence of growing barley on tracer movement through a silty soil in two lysimeters will be followed. At the first stage, an inert tracer is put on the two bare lysimeters and leached with constant irrigation. As steady-state flow can be assumed, it is possible to follow the tracer movement in the column by ERT and to identify regions of preferential flow and solute transport parameters. During the second experiment, the tracer will be applied to mature barley grown in the lysimeters. Combining the information about the water content obtained with TDR with the relation between water content, soil solution salinity and bulk electrical conductivity, the soil solution salinity distribution can be derived from images of bulk electrical conductivity obtained with ERT. Root growth will be monitored using a minirhizotron. By comparing the transport parameters obtained after these two experiments, the effect of root water on the transport process can be quantified. When the columns are washed out and the barley is harvested, the third phase will be carried out under the same steady state flow conditions as in the first experiment to investigate the effect of dead roots on soil structure. [less ▲]

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See detailEffects of crossbreeding on endocrine patterns determined in pregnant beef/dairy cows naturally infected with Neospora caninum.
Garcia-Ispierto, I.; Serrano-Perez, B.; Almeria, S. et al

in Theriogenology (2015), 83(4), 491-496

Neospora caninum is an intracellular coccidian parasite causing abortion worldwide in dairy cattle. Studies have shown that N caninum infection modifies endocrine patterns and that beef cows or cows with ... [more ▼]

Neospora caninum is an intracellular coccidian parasite causing abortion worldwide in dairy cattle. Studies have shown that N caninum infection modifies endocrine patterns and that beef cows or cows with a crossbreed pregnancy, especially for a greater maternal-paternal genetic distance, show a reduced risk of abortion when naturally infected compared with pure-breed Holstein Friesian (HF) pregnancies. This study examined the effects of crossbreeding on plasma progesterone (P4), pregnancy-associated glycoprotein (PAG)-1 and -2, and prolactin patterns produced during gestation in N caninum-infected beef/dairy cows. We analyzed 74 pregnancies in nonaborting cows carrying a single fetus established in 26 lactating HF cows bred with Holstein bulls (H-H), 13 HF cows bred with Limousin bulls (H-L), 12 HF cows used as recipients of transferred in vivo-produced frozen-thawed Rubia Gallega (beef breed; RG) embryos (H-RG-ET), and 23 RG suckling cows bred with RG bulls (RG-RG). Of the cows, 29 (39%) were seropositive for N caninum. Blood samples for hormone and placental protein determinations were collected on Days 30, 60, 90, 120, 150, and 180 of gestation. Procedures of repeated measures analysis of variance throughout gestation revealed higher PAG-1 levels in the H-L and H-RG-ET groups compared with H-H and RG-RG. Higher prolactin levels were detected in RG-RG than in the remaining groups. N caninum seropositivity and fetal genotype had a significant effect on PAG-2 concentrations, such that highest levels of PAG-2 occurred in RG-RG seropositive cows and lowest in H-H seropositive cows, whereas Neospora-seropositive cows showed lower P4 concentrations than their seronegative partners. In conclusion, chronic N caninum infection modifies endocrine patterns of PAG-2 and P4 during pregnancy, whereas PAG-1 and prolactin concentrations are affected by breed and fetal genotype, irrespective of Neospora infection status. [less ▲]

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