Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailThe dual parametrization for gluon GPDs
Semenov-Tyan-Shanskiy, Kirill ULg

in European Physical Journal A -- Hadrons & Nuclei (2010), 45

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailDual parametrization of GPDs versus the double distribution Ansatz
Polyakov, Maxim; Semenov-Tyan-Shanskiy, Kirill ULg

in European Physical Journal A -- Hadrons & Nuclei (2009), 40

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailDual Perturb and Combine Algorithm
Geurts, Pierre ULg

in Proceedings of AISTATS 2001, Eighth International Workshop on Artificial Intelligence and Statistics (2001)

In this paper, a dual perturb and combine algorithm is proposed which consists in producing the perturbed predictions at the prediction stage using only one model. To this end, the attribute vector of a ... [more ▼]

In this paper, a dual perturb and combine algorithm is proposed which consists in producing the perturbed predictions at the prediction stage using only one model. To this end, the attribute vector of a test case is perturbed several times by an additive random noise, the model is applied to each of these perturbed vectors and the resulting predictions are aggregated. An analytical version of this algorithm is described in the context of decision tree induction. From experiments on several datasets, it appears that this simple algorithm yields significant improvements on several problems, sometimes comparable to those obtained with bagging. When combined with decision tree bagging, this algorithm also improves accuracy in many problems. [less ▲]

Detailed reference viewed: 180 (2 ULg)
Full Text
Peer Reviewed
See detailDual Photon Absorptiometry of Lumbar Spine in West European (Belgian) Postmenopausal Females: Normal Range and Fracture Threshold
Reginster, Jean-Yves ULg; Denis, D.; Deroisy, Rita ULg et al

in Clinical Rheumatology (1990), 9(2), 220-4

Bone mineral content (BMC) and bone mineral density (BMD) of lumbar spine have been measured in 695 healthy postmenopausal and 64 type I osteoporotic Belgian, Caucasian females. Bone loss is strongly ... [more ▼]

Bone mineral content (BMC) and bone mineral density (BMD) of lumbar spine have been measured in 695 healthy postmenopausal and 64 type I osteoporotic Belgian, Caucasian females. Bone loss is strongly correlated to time elapse from menopause (Tm) with a maximum rate of bone loss during the first five years of menopause. BMC (gHA) = 461 + 0.662 ln Tm -0.481 (ln Tm)2 and BMD (gHA/cm2) = 0.91 + 0.00711 ln Tm - 0.00846 (ln Tm)2 (in both cases p less than 0.001 and Tm expressed in months of menopause). After 20 years of menopause, 50 to 60% of normal women have vertebral BMC and BMD values below the 90th percentile of women with vertebral fractures and, thus, might be considered to have asymptomatic osteoporosis. We conclude that prevention of postmenopausal osteoporosis should be initiated as soon as possible after the onset of menopause and that bone density screening should be extended in elderly in order to detect and allow treatment of asymptomatic "densitometric" osteoporosis. [less ▲]

Detailed reference viewed: 18 (3 ULg)
Full Text
See detailThe dual purpose Belgian Blue
Colinet, Frédéric ULg

Diverse speeche and writing (2010)

Detailed reference viewed: 35 (11 ULg)
Full Text
See detailThe dual purpose Red and White
Colinet, Frédéric ULg

Diverse speeche and writing (2010)

Detailed reference viewed: 14 (4 ULg)
Full Text
Peer Reviewed
See detailThe dual role of roads in the visual landscape: a case study in the area around Mechelen (Belgium)
Garré, Sarah ULg; Meeus, Steven; Gulinck, Hubert

in Landscape & Urban Planning (2009), 92(2), 125-135

Roads dominate our daily surroundings and are essential conditions of the access to the visual landscape. This paper focuses on the dual landscape role of secondary and tertiary roads in a semi-rural ... [more ▼]

Roads dominate our daily surroundings and are essential conditions of the access to the visual landscape. This paper focuses on the dual landscape role of secondary and tertiary roads in a semi-rural setting, to be understood as the access to scenery and as their direct influence to the landscape characteristics. A combination of techniques was used including a radiocentric morphological landscape analysis, a perception study on landscape photographs and a cumulative logit model to assess the factors of landscape appreciation in this kind of environment. The results show that roads do not entirely open up the information content of the visual landscape. Furthermore, roads and built fabric seem to have a negative impact on landscape appreciation. This result does not rely on the structures themselves, but on the artificial materials they are constructed of. The methodology applied proves to be useful and is probably applicable in other geographical contexts. It can be a supporting tool to plan and manage road networks for improvement of landscape quality, especially in parts of the countryside strongly affected by urban sprawl. [less ▲]

Detailed reference viewed: 26 (6 ULg)
Peer Reviewed
See detailThe Dual Role of Thymic Neurohypophysial-Related Self Peptides in T Cell Selection. Physiological and Pharmacological Implications
Geenen, Vincent ULg; Martens, Henri ULg; Robert, Françoise et al

in Annals of the New York Academy of Sciences (1993), 689

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailThe dual role of weather forecasts on changes in activity-travel behavior
Cools, Mario ULg; Creemers, Lieve

in Journal of Transport Geography (2013), 28

A deeper understanding of how human activity-travel behavior is affected by various weather conditions is essential for both policy makers and traffic managers. To unravel the ambiguity in findings ... [more ▼]

A deeper understanding of how human activity-travel behavior is affected by various weather conditions is essential for both policy makers and traffic managers. To unravel the ambiguity in findings reported in the literature, the main objective of this paper is to obtain an accurate assessment of how weather forecasts trigger changes in Flemish activity-travel behavior. To this end, data were collected by means of a stated adaptation experiment, which was administered both on the Internet and via traditional paper-and-pencil questionnaires. To address the main research question of this paper, two statistical techniques were adopted. The first technique is the computation of Pearson chi-square independence tests. The second approach is the estimation of a GEE-MNL-model. The results from both techniques underscore the dual role of weather forecasts on changes in activity-travel behavior. On the one hand, the results clearly illustrate the significant effect of forecasted weather; the likelihood of changes in activity-travel behavior significantly depends on the weather forecasted. On the other hand, different methods of acquiring weather information (exposure, media source, or perceived reliability) do not impact the probability of behavioral adaptations. This duality may be partially attributable to the discrepancy that exists between weather forecasts and true traffic and roadway conditions. Therefore, the implementation of a road weather information system that is directly linked to the weather forecasts is recommended. [less ▲]

Detailed reference viewed: 94 (11 ULg)
Full Text
Peer Reviewed
See detailThe dual role of weather forecasts on changes in activity-travel behavior
Cools, Mario ULg; Creemers, Lieve; Janssens, Davy et al

Conference (2011)

In previous studies, conflicting results could be found regarding the impact of weather forecasts on travel decisions, e.g. Khattak and De Palma (1997) found no significant effect of acquiring forecasted ... [more ▼]

In previous studies, conflicting results could be found regarding the impact of weather forecasts on travel decisions, e.g. Khattak and De Palma (1997) found no significant effect of acquiring forecasted weather information on the probability of adapting mode and departure time, whereas the results reported by Hagens (2005), Niina (2009) and Kilpelainen and Summala (2007) indicated that weather forecast do play an important role. Therefore this paper investigates the changes in activity-travel behavior in response to weather forecasts. The data for this study is collected by means of a stated adaptation survey, which is both administered on the internet and via a traditional paper and pencil questionnaire. In total, 595 respondents completed the survey. To obtain an optimal correspondence between the true population and the sample weights are assigned to the observation. Results indicate that weather information plays a dual role. On the one hand people do alter their activity-travel behavior in response to weather information, albeit these changes are not as pronounced when compared to actual weather. On the other hand the extent (frequency and media type) to which people are exposed to these weather forecasts appears to play only a marginal role. This dual role weather information plays in this study appears to be supported by the conflicting international literature and therefore revealing the underlying psychological motivations to change one's activity-travel behavior is a key challenge for further research. [less ▲]

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailDual stimuli-responsive coating designed through layer-by-layer assembly of PAA-b-PNIPAM block copolymers for the control of protein adsorption
Osypova, Alina; Magnin, Delphine; Sibret, Pierre ULg et al

in Soft Matter (2015), 11(41), 8154-8164

In this paper, we describe the successful construction, characteristics and interaction with proteins of stimuli-responsive thin nanostructured films prepared by layer-by-layer (LbL) sequential assembly ... [more ▼]

In this paper, we describe the successful construction, characteristics and interaction with proteins of stimuli-responsive thin nanostructured films prepared by layer-by-layer (LbL) sequential assembly of PNIPAM-containing polyelectrolytes and PAH. PAA-b-PNIPAM block copolymers were synthesized in order to benefit from (i) the ionizable properties of PAA, to be involved in the LbL assembly, and (ii) the sensitivity of PNIPAM to temperature stimulus. The impact of parameters related to the structure and size of the macromolecules (their molecular weight and the relative degree of polymerization of PAA and PNIPAM), and the interaction with proteins under physico-chemical stimuli, such as pH and temperature, are carefully investigated. The incorporation of PAA-b-PNIPAM into multilayered films is shown to be successful whatever the block copolymer used, resulting in slightly thicker films than the corresponding (PAA/PAH)n film. Importantly, the protein adsorption studies demonstrate that it is possible to alter the adsorption behavior of proteins on (PAA-b-PNIPAM/PAH)n surfaces by varying the temperature and/or the pH of the medium, which seems to be intimately related to two key factors: (i) the ability of PNIPAM units to undergo conformational changes and (ii) the structural changes of the film made of weak polyelectrolytes. The simplicity of construction of these PNIPAM block copolymer-based LbL coatings on a large range of substrates, combined with their highly tunable features, make them ideal candidates to be employed for various biomedical applications requiring the control of protein adsorption. [less ▲]

Detailed reference viewed: 25 (6 ULg)
Full Text
Peer Reviewed
See detailA dual strategy to cope with high light in Chlamydomonas reinhardtii
Allorent, G; Tokutsu, R; Roach, T et al

in Plant Cell (2013), 25(2), 545-557

Absorption of light in excess of the capacity for photosynthetic electron transport is damaging to photosynthetic organisms. Several mechanisms exist to avoid photodamage, which are collectively referred ... [more ▼]

Absorption of light in excess of the capacity for photosynthetic electron transport is damaging to photosynthetic organisms. Several mechanisms exist to avoid photodamage, which are collectively referred to as nonphotochemical quenching. This term comprises at least two major processes. State transitions (qT) represent changes in the relative antenna sizes of photosystems II and I. High energy quenching (qE) is the increased thermal dissipation of light energy triggered by lumen acidification. To investigate the respective roles of qE and qT in photoprotection, a mutant (npq4 stt7-9) was generated in Chlamydomonas reinhardtii by crossing the state transition–deficient mutant (stt7-9) with a strain having a largely reduced qE capacity (npq4). The comparative phenotypic analysis of the wild type, single mutants, and double mutants reveals that both state transitions and qE are induced by high light. Moreover, the double mutant exhibits an increased photosensitivity with respect to the single mutants and the wild type. Therefore, we suggest that besides qE, state transitions also play a photoprotective role during high light acclimation of the cells, most likely by decreasing hydrogen peroxide production. These results are discussed in terms of the relative photoprotective benefit related to thermal dissipation of excess light and/or to the physical displacement of antennas from photosystem II. [less ▲]

Detailed reference viewed: 33 (11 ULg)
Full Text
Peer Reviewed
See detailDual substrate specificity of Bacillus subtilis PBP4a
Nemmara, Venkatesh V.; Adediran, S. A.; Dave, Kinjal et al

in Biochemistry (2013), 52

Bacterial DD-peptidases are the targets of the β-lactam antibiotics. The sharp increase in bacterial resistance toward these antibiotics in recent years has stimulated the search for non- β-lactam ... [more ▼]

Bacterial DD-peptidases are the targets of the β-lactam antibiotics. The sharp increase in bacterial resistance toward these antibiotics in recent years has stimulated the search for non- β-lactam alternatives. The substrates of DD-peptidases are elements of peptidoglycan from bacterial cell walls. Attempts to base DD-peptidase inhibitor design on peptidoglycan structure, however, have not been particularly successful to date because the specific substrates for most of these enzymes are unknown. It is known, however, that the preferred substrates of low-molecular mass (LMM) class B and C DD-peptidases contain the free N-terminus of the relevant peptidoglycan. Two very similar LMMC enzymes, for example, the Actinomadura R39 DD-peptidase and Bacillus subtilis PBP4a, recognize a D-α-aminopimelyl terminus. The peptidoglycan of B. subtilis in the vegetative stage, however, has the N-terminal D-α-aminopimelyl carboxylic acid amidated. The question is, therefore, whether the DD-peptidases of B. subtilis are separately specific to carboxylate or carboxamide or have dual specificity. This paper describes an investigation of this issue with B. subtilis PBP4a. This enzyme was indeed found to have a dual specificity for peptide substrates, both in the acyl donor and in the acyl acceptor sites. In contrast, the R39 DD-peptidase, from an organism in which the peptidoglycan is not amidated, has a strong preference for a terminal carboxylate. It was also found that acyl acceptors, reacting with acyl−enzyme intermediates, were preferentially D-amino acid amides for PBP4a and the corresponding amino acids for the R39 DD-peptidase. Examination of the relevant crystal structures, aided by molecular modeling, suggested that the expansion of specificity in PBP4a accompanies a change of Arg351 in the R39 enzyme and most LMMC DD-peptidases to histidine in PBP4a and its orthologs in other Bacillus sp. This histidine, in neutral form at pH 7, appeared to be able to favorably interact with both carboxylate and carboxamide termini of substrates, in agreement with the kinetic data. It may still be possible, in specific cases, to combat bacteria with new antibiotics based on particular elements of their peptidoglycan structure. [less ▲]

Detailed reference viewed: 15 (0 ULg)
Full Text
Peer Reviewed
See detailDual tachykinin NK1/NK2 antagonist DNK333 inhibits neurokinin A-induced bronchoconstriction in asthma patients
Joos, G. F.; Vincken, W.; Louis, Renaud ULg et al

in European Respiratory Journal (2004), 23(1), 76-81

Inhalation of neurokinin A (NKA) causes bronchoconstriction in patients with asthma. In vitro both tachykinin NK1 and NK2 receptors can mediate airway contraction. In this study the authors examined the ... [more ▼]

Inhalation of neurokinin A (NKA) causes bronchoconstriction in patients with asthma. In vitro both tachykinin NK1 and NK2 receptors can mediate airway contraction. In this study the authors examined the effects of a single dose of the dual tachykinin NK1/NK2 receptor antagonist, DNK333, on NKA-induced bronchoconstriction in asthma. A total of 19 male adults with mild asthma completed a randomised, double-blind, placebo-controlled crossover trial. Increasing concentrations of NKA (3.3 x 10(-9) to 1.0 x 10(-6) mol(.)mL(-1)) were inhaled at 1 and 10 h intervals after a single oral dosing with either DNK333 (100 mg) or a placebo. It was observed that DNK333 did not affect baseline lung function but did protect against NKA-induced bronchoconstriction in those patients. The mean log(10) provocative concentration causing a 20% fall in forced expiratory volume in one second for NKA was -5.6 log(10) mol(.)mL(-1) at 1 h after DNK333 treatment and -6.8 log(10) mol(.)mL(-1) after placebo. This was equivalent to a difference of 4.08 doubling doses, which decreased to a difference of 0.90 doubling doses 10 h after treatment. The results shown in this report indicate that DNK333 blocks neurokinin A-induced bronchoconstriction in patients with asthma. [less ▲]

Detailed reference viewed: 42 (3 ULg)
Full Text
Peer Reviewed
See detailA dual thromboxane inhibitor and thromboxane receptor antagonist prevents pig myocardial infarction induced by coronary thrombosis
Rolin, S.; Petein, M.; Tchana-Sato, Vincent ULg et al

in European Heart Journal (2003), 24(Suppl. S), 325

Detailed reference viewed: 6 (2 ULg)
Full Text
Peer Reviewed
See detailDual time point fluorine-18 fluorodeoxyglucose positron emission tomography: a potential method to differentiate malignancy from inflammation and normal tissue in the head and neck.
Hustinx, Roland ULg; Smith, R. J.; Benard, F. et al

in European Journal of Nuclear Medicine (1999), 26(10), 1345-8

Fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) studies imaging FDG PET imaging is used to detect and stage head and neck cancers. However, the variable physiologic uptake of FDG ... [more ▼]

Fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) studies imaging FDG PET imaging is used to detect and stage head and neck cancers. However, the variable physiologic uptake of FDG in different normal structures as well as at inflammatory sites may either obscure a tumor focus or be falsely interpreted to represent tumor activity. Twenty-one patients (9 men, 12 women, median age 59) were scanned serially at two time points, one at 70 min (range 47-112) and the second at 98 min (77-142) after the intravenous injection of 4.3 MBq/kg of FDG. The mean interval between emission scans was 28 min (13-49). Transmission scans were performed and regions of interest (ROIs) were overlayed on the fully corrected images. Standardiued uptake values (SUVs) were generated for the cerebellum, tongue, larynx, every lesion, and a matched contralateral site. Follow-up and pathologic studies revealed 18 squamous cell carcinomas and nine inflammatory or infectious lesions. Tumor SUVs were 4.0+/-1.6 (mean +/- SD) for the first scan and 4. 5+/-2.2 for the second scan. Contralateral SUVs were 1.2+/-0.5 and 1. 1+/-0.5 for the two scans. Tumor SUVs increased by 12%+/-12% as compared with a 5%+/-17% decrease for contralateral sites (P<0.05). SUVs for inflammatory sites (2.0+/-0.7 and 2.0+/-0.9), cerebellum (4. 2+/-1.3 and 4.3+/-1.4), tongue (1.8+/-0.4 and 1.9+/-0.5) and larynx (1.5+/-0.6 and 1.5+/-0.6) remained constant over time (+0.6%, +2.8%, +1.4%, and -2.4%; P<0.05 when compared with tumor SUV changes). The ratio tumor/contralateral SUV increased by 23%+/-29% over time while this ratio for inflamed sites increased by only 5%+/-15% (P=0.07). The time interval between scans correlated with increase in SUV for tumors (r=0.55, P<0.05) but not for any of the other ROIs. Separation was superior when studies were performed more than 30 min apart (P<0.05). These preliminary data suggest that dual time point imaging compatible with a clinical study protocol is helpful in differentiating malignant lesions from inflammation and normal tissues, especially when separated by a sufficient time interval. [less ▲]

Detailed reference viewed: 27 (2 ULg)
Full Text
Peer Reviewed
See detailDual time-point FDG-PET imaging to distinguish tumor from normal and inflammatory sites in the head and neck.
HUSTINX, Roland ULg; SMITH, RJ.; ROSENTHAL, DI. et al

in Journal of Nuclear Medicine (The) (1999), 40

Detailed reference viewed: 5 (0 ULg)
Full Text
See detailThe dual-gain 10 µm back-thinned 3k x 3k CMOS-APS detector of the Solar Orbiter Extreme UV Imager
Halain, Jean-Philippe ULg; Debaize, Arnaud ULg; Gillis, Jean-Marie ULg et al

in Proceedings of SPIE (2014), 9144

The Extreme Ultraviolet Imager (EUI) on-board the Solar Orbiter mission will provide image sequences of the solar atmosphere at selected spectral emission lines in the extreme and vacuum ultraviolet. For ... [more ▼]

The Extreme Ultraviolet Imager (EUI) on-board the Solar Orbiter mission will provide image sequences of the solar atmosphere at selected spectral emission lines in the extreme and vacuum ultraviolet. For the two Extreme Ultraviolet (EUV) channels of the EUI instrument, low noise and radiation tolerant detectors with low power consumption and high sensitivity in the 10-40 nm wavelength range are required to achieve the science objectives. In that frame, a dual-gain 10 µm pixel pitch back-thinned 1k x 1k Active Pixel Sensor (APS) CMOS prototype has been tested during the preliminary development phase of the instrument, to validate the pixel design, the expected EUV sensitivity and noise level, and the capability to withstand the mission radiation environment. Taking heritage of this prototype, the detector architecture has been improved and scaled up to the required 3k x 3k array. The dynamic range is increased, the readout architecture enhanced, the power consumption reduced, and the pixel design adapted to the required stitching. The detector packaging has also been customized to fit within the constraints imposed by the camera mechanical, thermal and electrical boundaries. The manufacturing process has also been adapted and back-thinning process improved. Once manufactured and packaged, a batch of sensors will undergo a characterization and calibration campaign to select the best candidates for integration into the instrument qualification and flight cameras. The flight devices, within their cameras, will then be embarked on the EUI instrument, and be the first scientific APS-CMOS detectors for EUV observation of the Sun. [less ▲]

Detailed reference viewed: 96 (12 ULg)