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Peer Reviewed
See detailDevelopment of specific antibodies for the quantificaion of plasma insulin-like growth factor-binding protein-3 in cattle.
Renaville, Robert ULiege; Bertozzi, C.; Hetzel, S. et al

in Journal of Animal Science (2001), 79(suppl 1, N°1610), 388

Detailed reference viewed: 8 (1 ULiège)
Peer Reviewed
See detailDevelopment of specific antibodies for the quantification of plasma insulin-like growth factor-binding protein-3 in cattle.
Renaville, Robert ULiege; Bertozzi, Carlo; Hetzel, Sandrine et al

Poster (2001, July)

Detailed reference viewed: 9 (0 ULiège)
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Peer Reviewed
See detailDevelopment of specific antibodies mediating antibody-dependent cell-mediated cytotoxicity following experimental infection of cattle with bovine herpesvirus 1 and subsequent viral reactivation.
Hanton, G.; Thiry, Etienne ULiege; Brochier, B. et al

in Veterinary Microbiology (1986), 11(1-2), 51-9

Evolution of sensitizing antibodies involved in antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-complement cell lysis and complement-facilitated ADCC was followed in bulls after primary ... [more ▼]

Evolution of sensitizing antibodies involved in antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-complement cell lysis and complement-facilitated ADCC was followed in bulls after primary infection by a wild strain of infectious bovine rhinotracheitis virus (bovine herpesvirus 1; BHV-1) and after experimental reactivation of the virus. These antibodies were detected between the 4th and the 7th day after primary infection, reached a maximum level after 2 weeks and rose slightly after reactivation of the virus following dexamethasone treatment. The presence of endogenous complement slightly enhanced the ADCC reaction. [less ▲]

Detailed reference viewed: 21 (0 ULiège)
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See detailDevelopment of Specifications and Performance Criteria for Surface Preparation Based on Issues Related to Bond Strength
Bissonnette, Benoît; Courard, Luc ULiege; Garbacz, Andrzej et al

Report (2017)

In addition to the development of a satisfactory test procedure and recommendations to improve the overall quality of concrete repair works, the authors of this proposal intend to collaborate with various ... [more ▼]

In addition to the development of a satisfactory test procedure and recommendations to improve the overall quality of concrete repair works, the authors of this proposal intend to collaborate with various representatives from public agencies and from the industry to facilitate technological transfer. Presentations will be made in conferences and workshops in North America and Europe. At the end of the project, the results shall include two MSc theses and at least two papers in major journals, such as Concrete International or ACI Materials Journal. Also, the project should provide the basis towards a standard procedure for the evaluation of superficial cohesion of concrete, in relation with surface preparation and concrete removal techniques. Finally, recommendations and specifications could be incorporated in future versions of the ACI-ICRI Manual of Concrete Repairs as well as in DOT’s specifications. [less ▲]

Detailed reference viewed: 40 (4 ULiège)
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See detailThe development of Structural Fire Engineering over the past 25 years and issues for the future
Franssen, Jean-Marc ULiege

Conference (2015, October 15)

This talk presents a series of thoughts of the author from his observation of the evolution of structural fire engineering since the beginning of his career Experimental research works are discussed ... [more ▼]

This talk presents a series of thoughts of the author from his observation of the evolution of structural fire engineering since the beginning of his career Experimental research works are discussed, either on the behavior of materials or on the behavior of structures. The rest of the presentation is dedicated to calculation methods: tabulated data, simple calculation models and general calculation models. For numerical calculation models, the presentation contains a brief history of appearance of different software, of their objectives, of their capabilities… Some examples are presented of structures recently modelled in real applications. Possible abusive utilizations of numerical modelling are also shown. The presentation ends with a presentation of some challenges that the discipline is facing for the future. [less ▲]

Detailed reference viewed: 40 (2 ULiège)
See detailThe development of subordinate clauses in Old Swedish - an example of contact-induced language change?
Zeevaert, Ludger ULiege

in Zanchi, Anna (Ed.) Skáldamjöðurinn. Selected proceedings of the UCL graduate symposia in Old Norse literature and philology, 2005-2006 (2008)

Detailed reference viewed: 28 (0 ULiège)
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See detailThe development of sustainable mobility strategy in Belgian cities
Crutzen, Nathalie ULiege; Qian, Wei; Bounazef, Djida ULiege

Scientific conference (2017, June)

Nowadays, city local governments focus their strategic vision on the development of the urban sustainability. For this, they develop drivers, strategies, structures on green local improvements. To be ... [more ▼]

Nowadays, city local governments focus their strategic vision on the development of the urban sustainability. For this, they develop drivers, strategies, structures on green local improvements. To be sustainable, cities reinforce actions and plans on resource management, mobility, climate, building and public spaces. In order to be sustainable and smart, challenges are set to ensure successful implementation of sustainable mobility strategies through the development of appropriate policies, actions, decisions and controls. The development of sustainable mobility strategy requires the involvement of strategic actors, infrastructures, funding and socio-demographic parameters. To ensure this, sustainable mobility strategy has to be strengthen by an efficient management control system and a real measurement of institutional factors’ risk. The development of mobility controls ensures homogeneity between behaviours, decisions, objectives and strategies for mobility issues. In order to make the link between control, strategy and sustainability, new researches propose new frameworks and systems. These frameworks reinforce the strategic contribution of values, rules, monitoring and enhancing awareness and interactions. Based on that, the management control framework of Malmi and Brown is more and more associated with the implementation of sustainable strategies. This paper explores the development of sustainable mobility strategies in two Belgian cities (Namur and Leuven). To analyse how cilty local governments implement, control and develop mobility strategies and plans, this paper refers to Malmi and Brown’s model. The research proposes two hypotheses that set the importance of the integration of an adequate sustainable mobility control system and the institutional factors on the design and the use of mobility strategy control. This paper proposes a new conceptual model to support the development of sustainable mobility strategy. For this, the choice of two Belgian cities is made according to similarities (population size, explicit will to develop sustainable mobility strategy, focus on sustainable transport, initiation period of mobility issues’ implementation, number of person in charge of mobility, level of willingness to develop mobility system, focus on car free and strategic mobility challenges) and differences (region, language, regulative factors, normative factors and cognitive factors). To test our conceptual framework, an explorative qualitative case study is done in these two Belgian city local governments. The data collection requires a fieldwork of 12 weeks, 54 internal and external documents, and 20 semi-structured interviews (mobility managers, politicians, sustainability managers, policemen and administrative workers). Results shows differences between the implementation and development of Namur and Leuven. Leuven has an average quality of sustainable mobility control system. Leuven requires developing new adapted indicators to face new city challenges and more effective collaborations between involved departments and actors. The case of Namur shows that its sustainable mobility control system is weak because of the non-adapted indicators to strategy and the weakness of the formal structure of mobility strategy. Results identify different institutional factors that have a significant impact on the development of sustainable mobility strategy; the most relevant are formal regulations, political power, local cultures, support of direct and indirect actors and the sensitiveness on sustainable culture. The proposed conceptual model also highlights if the impact of mobility strategy controls and institutional influences have a weak, medium or strong impact on the development of mobility strategy. Results validate our proposed conceptual model. However, this model has to be tested on other sustainability issues (energy, green building, green housing, green and neutral climate), cities and regions. [less ▲]

Detailed reference viewed: 98 (6 ULiège)
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See detailDevelopment of techniques for rapid production of rattan seedlings
Kouakou, K. L.; Zoro Bi, I. A.; Baudoin, Jean-Pierre ULiege

Conference given outside the academic context (2008)

Detailed reference viewed: 30 (3 ULiège)
See detailDevelopment of the Abilities to Acquire New Orthographic Representations from Grades 2 to 6
Binamé, Florence ULiege; Poncelet, Martine ULiege

Conference (2014, May 27)

Unlike English, little attention has been accorded to orthographic learning in French which has a challenging spelling due to its high level of inconsistency. There is evidence that the mastery of ... [more ▼]

Unlike English, little attention has been accorded to orthographic learning in French which has a challenging spelling due to its high level of inconsistency. There is evidence that the mastery of alphabetic decoding is critical to acquire word-specific orthographic representations (Share 1995). It is also generally admitted that orthographic processing skills are involved in orthographic learning beyond the core phonological component. Even if these skills still remain underspecified, research particularly focuses on the sensitivity to orthographic constraints. While Pacton et al. (2013) have shown that graphotactic knowledge influences the learning of new spellings, little is known about the development of this knowledge over time. Our aim was to determine the developmental trajectory of orthographic word form acquisition abilities within the French orthography by assessing the speed of acquisition of new orthographic forms as well as the sensitivity to orthographic regularities. Five groups of forty French-speaking children from grades 2 to 6 took part in the study. We proposed two experimental tasks. The first consisted of an orthographic learning of 10 new orthographic forms (inconsistent in spelling) by using a repeated spelling paradigm. In practice, children were firstly asked to read aloud each item once. Then, the experimenter dictated each item ten times in a mixed order. The capacity of retention of the new representations was assessed one week later with a dictation task. The second task aimed at determining the sensitivity to different French orthographic regularities by means of an orthographic choice task containing 62 pairs of non-words homophones. Moreover, general reading and spelling abilities were also assessed. Results show that the speed of orthographic learning and the capacity of long-term retention significantly increase during the first years but do not differ anymore between grades 4-5 and 5-6, suggesting that older children have reached a nearly maximal potential in their learning capacities. Nevertheless, the general orthographic abilities, which are more dependent on scholar knowledge, continue to develop significantly during school years. Furthermore, sensitivity to orthographic regularities increases significantly only from grade 2 to 3, indicating that children as soon as 9 years-old are already able to extract different graphotactic patterns of their writing system. Pacton, S., Sobaco, A., Fayol, M., & Treiman, R. (2013). How does graphotactic knowledge influence children’s learning of new spellings? Frontiers in Psychology, 4, 1-10. Share, D. (1995). Phonological recoding and self-teaching: sine qua non of reading acquisition. Cognition 55, 151-218. [less ▲]

Detailed reference viewed: 87 (8 ULiège)
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Peer Reviewed
See detailThe development of the abilities to acquire novel detailed orthographic representations and maintain them in long-term memory
Binamé, Florence ULiege; Poncelet, Martine ULiege

in Journal of Experimental Child Psychology (2016), 143

Previous studies have clearly demonstrated that the development of orthographic representations relies on phonological recoding. However, substantial questions persist about the remaining unexplained ... [more ▼]

Previous studies have clearly demonstrated that the development of orthographic representations relies on phonological recoding. However, substantial questions persist about the remaining unexplained variance in the acquisition of word-specific orthographic knowledge that is still underspecified. The main aim of this study was to explore whether two cognitive factors—sensitivity to orthographic regularities and short-term memory (STM) for serial order—make independent contributions to the acquisition of novel orthographic representations beyond that of the phonological core component and the level of preexisting word-specific orthographic knowledge. To this end, we had children from second to sixth grades learn novel written word forms using a repeated spelling practice paradigm. The speed at which children learned the word forms and their long-term retention (1 week and 1 month later) were assessed. Hierarchical regression analyses revealed that phonological recoding, preexisting word-specific orthographic knowledge, and order STM explained a portion of the variance in orthographic learning speed, whereas phonological recoding, preexisting word-specific orthographic knowledge, and orthographic sensitivity each explained a portion of variance in the long-term retention of the newly created orthographic representations. A secondary aim of the study was to determine the developmental trajectory of the abilities to acquire novel orthographic word forms over the course of primary schooling. As expected, results showedan effect of age on both learning speed and long-term retention. The specific roles of orthographic sensitivity and order STM as independent factors involved in different steps of orthographic learning are discussed. [less ▲]

Detailed reference viewed: 60 (14 ULiège)
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Peer Reviewed
See detailDevelopment of the Crohn's disease digestive damage score, the Lemann score.
Pariente, Benjamin; Cosnes, Jacques; Danese, Silvio et al

in Inflammatory Bowel Diseases (2011), 17(6), 1415-22

Crohn's disease (CD) is a chronic progressive destructive disease. Currently available instruments measure disease activity at a specific point in time. An instrument to measure cumulative structural ... [more ▼]

Crohn's disease (CD) is a chronic progressive destructive disease. Currently available instruments measure disease activity at a specific point in time. An instrument to measure cumulative structural damage to the bowel, which may predict long-term disability, is needed. The aim of this article is to outline the methods to develop an instrument that can measure cumulative bowel damage. The project is being conducted by the International Program to develop New Indexes in Crohn's disease (IPNIC) group. This instrument, called the Crohn's Disease Digestive Damage Score (the Lemann score), should take into account damage location, severity, extent, progression, and reversibility, as measured by diagnostic imaging modalities and the history of surgical resection. It should not be "diagnostic modality driven": for each lesion and location, a modality appropriate for the anatomic site (for example: computed tomography or magnetic resonance imaging enterography, and colonoscopy) will be used. A total of 24 centers from 15 countries will be involved in a cross-sectional study, which will include up to 240 patients with stratification according to disease location and duration. At least 120 additional patients will be included in the study to validate the score. The Lemann score is expected to be able to portray a patient's disease course on a double-axis graph, with time as the x-axis, bowel damage severity as the y-axis, and the slope of the line connecting data points as a measure of disease progression. This instrument could be used to assess the effect of various medical therapies on the progression of bowel damage. [less ▲]

Detailed reference viewed: 109 (2 ULiège)
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See detailDevelopment of the Geer basin Hydrological model for climatic scenarios and first results about impacts evaluation
Goderniaux, Pascal ULiege; Brouyère, Serge ULiege; Orban, Philippe ULiege et al

Report (2008)

A surface – subsurface flow numerical model of the Geer basin (465 km²) has been implemented to assess the possible impacts of climate change on the groundwater resources. This model is physically-based ... [more ▼]

A surface – subsurface flow numerical model of the Geer basin (465 km²) has been implemented to assess the possible impacts of climate change on the groundwater resources. This model is physically-based, spatially-distributed and it integrates totally the groundwater and surface water. Simulations were performed using 6 climate change scenarios generated by the University of Newcastle-Upon-Tyne. These scenarios simulate changes in the amplitude, but also in the frequency and persistence of some meteorological events. First results show that, according the implemented flow model and the used climatic scenarios, significant decreases are expected in the groundwater levels (up to 12 meters) and in the surface water flow rates (reduction between 16% and 32%) [less ▲]

Detailed reference viewed: 26 (4 ULiège)
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Peer Reviewed
See detailDevelopment of the interfacial air layer in the non-aerated region of high-velocity spillway flows. Instabilities growth, entrapped air and influence on the self-aeration onset
Valero Huerta, Daniel ULiege; Bung, Daniel B

in International Journal of Multiphase Flow (2016), 84

Self-aeration is traditionally explained by the water turbulent boundary layer outer edge intersection with the free surface. This paper presents a discussion on the commonly accepted hypothesis behind ... [more ▼]

Self-aeration is traditionally explained by the water turbulent boundary layer outer edge intersection with the free surface. This paper presents a discussion on the commonly accepted hypothesis behind the computation of the critical point of self-aeration in spillway flows and a new formulation is proposed based on the existence of a developing air flow over the free surface. Upstream of the inception point of self-aeration, some surface roughening has been often reported in previous studies which consequently implies some entrapped air transport and air–water flows coupling. Such air flow is proven in this study by presenting measured air velocities and computing the air boundary layer thickness for a 1V:2H smooth chute flow. Additionally, the growth rate of free surface waves has been analysed by means of Ultrasonic Sensors measurements, obtaining also the entrapped air concentration. High-speed camera imaging has been used for qualitative study of the flow perturbations. [less ▲]

Detailed reference viewed: 19 (5 ULiège)
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Peer Reviewed
See detailDevelopment of the lemann index to assess digestive tract damage in patients with Crohn's disease.
Pariente, Benjamin; Mary, Jean-Yves; Danese, Silvio et al

in Gastroenterology (2015), 148(1), 52-63

BACKGROUND & AIMS: There is a need for a scoring system that provides a comprehensive assessment of structural bowel damage, including stricturing lesions, penetrating lesions, and surgical resection, for ... [more ▼]

BACKGROUND & AIMS: There is a need for a scoring system that provides a comprehensive assessment of structural bowel damage, including stricturing lesions, penetrating lesions, and surgical resection, for measuring disease progression. We developed the Lemann Index and assessed its ability to measure cumulative structural bowel damage in patients with Crohn's disease (CD). METHODS: We performed a prospective, multicenter, international, cross-sectional study of patients with CD evaluated at 24 centers in 15 countries. Inclusions were stratified based on CD location and duration. All patients underwent clinical examination and abdominal magnetic resonance imaging analyses. Upper endoscopy, colonoscopy, and pelvic magnetic resonance imaging analyses were performed according to suspected disease locations. The digestive tract was divided into 4 organs and subsequently into segments. For each segment, investigators collected information on previous operations, predefined strictures, and/or penetrating lesions of maximal severity (grades 1-3), and then provided damage evaluations ranging from 0.0 (no lesion) to 10.0 (complete resection). Overall level of organ damage was calculated from the average of segmental damage. Investigators provided a global damage evaluation (from 0.0 to 10.0) using calculated organ damage evaluations. Predicted organ indexes and Lemann Index were constructed using a multiple linear mixed model, showing the best fit with investigator organ and global damage evaluations, respectively. An internal cross-validation was performed using bootstrap methods. RESULTS: Data from 138 patients (24, 115, 92, and 59 with upper tract, small bowel, colon/rectum, and anus CD location, respectively) were analyzed. According to validation, the unbiased correlation coefficients between predicted indexes and investigator damage evaluations were 0.85, 0.98, 0.90, 0.82 for upper tract, small bowel, colon/rectum, anus, respectively, and 0.84 overall. CONCLUSIONS: In a cross-sectional study, we assessed the ability of the Lemann Index to measure cumulative structural bowel damage in patients with CD. Provided further successful validation and good sensitivity to change, the index should be used to evaluate progression of CD and efficacy of treatment. [less ▲]

Detailed reference viewed: 151 (7 ULiège)
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Peer Reviewed
See detailDevelopment of the National Forest Inventory in Luxembourg
Rondeux, Jacques ULiege; Wagner, Marc

in Tomppo, Erkki; Gschwantner, Thomas; Lawrence, Mark (Eds.) et al National Forest Inventories - Pathways for common reporting (2010)

Detailed reference viewed: 26 (6 ULiège)
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Peer Reviewed
See detailDevelopment of the Osteoporosis Risk Assessment by Composite Linear Essay (ORACLE)
Richy, Florent; Uhoda, Emmanuelle ULiege; Reginster, Jean-Yves ULiege

in Osteoporosis International (2002, November), 13(Suppl.3), 11

Detailed reference viewed: 15 (2 ULiège)