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See detailEffect of bovine Azawak colostrum administration on plasma protein profile in red kid.
Abdou, Harouna ULg; Marichatou, Hamani; Beckers, Jean-François ULg et al

Poster (2012, October 11)

This study evaluated the impact of heterologous Azawak colostrum administration on plasma protein profile in red kids from Niger. Forty (40) newborn kids were affected to one of two treatments: control ... [more ▼]

This study evaluated the impact of heterologous Azawak colostrum administration on plasma protein profile in red kids from Niger. Forty (40) newborn kids were affected to one of two treatments: control group (access to water and the mother) and colostrum group (access to the mother, water and additional 50 ml of colostrum Azawak/animal the day of birth, then 25ml/animal/day from the 2nd to 15th day). Blood samples (10ml/animal) were obtained at the age of 10 and 30 days by jugular puncture into EDTA vacutainer tubes. The quantification of total protein was performed by the Biuret method. The agarose gel electrophoresis was used to determine serum levels of albumin, ɑ-globulin, β1-globulin, β2-globulin, γ-globulin and finally the albumin/globulin ratio. In general, the average concentrations of these proteins obtained at both ages reached higher values in colostrum than in control group. At day 10, the colostrum group tended to show (P <0.07) higher levels for ɑ-globulin and showed higher values (P <0.04) for β1-globulin. At day 30, total protein and β2-globulins were higher in colostrum group. The administration of heterologous colostrum in kid seems to have positive effects on some plasma parameters. It would be worth to discriminate the plasma proteins derived from bovine and maternal colostra. [less ▲]

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See detailEffect of bovine colostrum administration on plasma protein profile, growth, and survival in Red kid.
Abdou, Harouna ULg; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Small Ruminant Research (2013), 117

This study evaluated the effect of colostrum from Azawak cows on plasma protein profile, 24 growth, and survival in Red kids from Niger. Forty (40) newborn kids were allocated to one 25 of two treatment ... [more ▼]

This study evaluated the effect of colostrum from Azawak cows on plasma protein profile, 24 growth, and survival in Red kids from Niger. Forty (40) newborn kids were allocated to one 25 of two treatment-groups: control (free access to water and the mother) and colostrum (free 26 access to water and the mother, but with additional 50 mL of colostrum/animal/day of birth 27 and 25 mL/animal/day from the 2nd to 15th day of age). Blood samples were collected into 28 EDTA vacutainer tubes by jugular puncture at 10 and 30 days of age. Total protein was 29 quantified by the Biuret method. The agarose gel electrophoresis was used to determine the 30 serum levels of albumin, -globulin, β1-globulin, β2-globulin, γ-globulin and the 31 albumin/globulin ratio. The animals from the colostrum group showed higher body weight 32 and average daily gain when compared to the control group (P < 0.001). The average 33 concentration in protein at the both sampling times reached higher values in the colostrum 34 than in the control group. At D10, the colostrum group tended (P < 0.07) to show higher 35 levels of -globulin and had higher values (P < 0.05) for β1-globulin. At D30, total protein 36 and β2-globulins were higher in colostrum group. Colostrum from Azawak cows seems to 37 have positive effects on some plasma proteins levels and on growth rate in Red kids. [less ▲]

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See detailEffect of bovine colostrum intake on growth, reproductive parameters and survival in red kids
Harouna, Abdou; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Journal of Animal Physiology & Animal Nutrition (2014), 98(5), 845-852

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition ... [more ▼]

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition, fertility, fecundity, prolificacy) and mortality rate among red kids. The study was conducted at the goat farm secondary centre of Maradi in Niger from September 2010 to September 2011. The control animals (n = 20) were left with their mother, while the treatment animals (n = 20) received in addition 50 ml/animal/day of bovine colostrum at birth and 15 ml/animal/day from d2 to d15. Weight was measured weekly from birth to d365. Mortalities were also recorded over the same period. For reproductive parameters, observations began at weaning (d197). Growth rate was higher (p < 0.001) in supplemented animal, and the treatment effects on ADG were observed up to 150 day after the end of supplementation. A similar long-lasting trend was also observed in relation to the mortality rate (25% for ColG vs. 55% for ConG; p = 0.05). The age at first kidding tended to be lower in the treated group (13.8 0.7 vs. 14.1 0.8 month; p < 0.1). In conclusion, mild bovine colostrum supplementation induces a long-lasting positive impact on growth rate and to a lower extent on reproduction parameters and survival rate. [less ▲]

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See detailEffect of bovine colostrum on growth and survival in Red kids during the first year of life.
Abdou, Harouna ULg; Marichatou, Hamani; Beckers, Jean-François ULg et al

Poster (2014, October 17)

The aim of this work was to measure the effect of supplementation with bovine colostrum among newborn Red goats breastfed in breeding conditions for semi-intensive type of Niger. The study was conducted ... [more ▼]

The aim of this work was to measure the effect of supplementation with bovine colostrum among newborn Red goats breastfed in breeding conditions for semi-intensive type of Niger. The study was conducted in Secondary Goat Breeding Center of Maradi (SGBCM). Forty newborn kids, regardless of sexe, were divided randomly into two groups: a "T-Control " group receiving only breast milk per feeding (n = 20) and a "C-Colostrum" group having the same diet but supplemented with bovine colostrum thawed (50 ml the first day of life, then 25 ml in 2 meals/ day between the ages of 2 and 15d, n = 20). The results indicate that supplementation with bovine colostrum in the first 15 days of life, increases the growth of kids until weaning (P<0.001), modifie some barymetric changes some settings improves health status and reduces the mortality rate. To our knowledge, in the studied environment, this work is original and seems to bring new knowledges likely to have practical applications in areas with farming conditions quite difficult. [less ▲]

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See detailEffect of bovine colostrum on the serum insulin-like growth factor-I (IGF-I), the IGF binding proteins-2 and -3 and the thyroid hormones in weaning piglets
Boudry, Christelle ULg; Dehoux, Jean-Paul; Colinet, Frédéric ULg et al

in Archiv Tierzucht (2010), 53(6), 675-688

This study examined the effect of a bovine colostrum supplementation on growth performance, feed intake and the hormonal response of piglets at weaning. Ninety-six newly-weaned piglets were assigned for ... [more ▼]

This study examined the effect of a bovine colostrum supplementation on growth performance, feed intake and the hormonal response of piglets at weaning. Ninety-six newly-weaned piglets were assigned for four weeks to one of the two treatments: Control (diet with bovine milk whey) and Colostrum (diet with bovine colostrum whey) treatments. The supplements were incorporated in a commercial diet at 20 g/kg during the first 2 weeks after weaning and lowered to 10 g/kg for the next 2 weeks. Body weight and feed intake were measured weekly. Blood samples were taken weekly for determination of circulating IGF-I, its binding proteins and the thyroid hormones (T3 and T4). During the first week of the trial, the Colostrum-fed piglets presented improved growth performance, feed intake and feed efficiency and a higher concentration in circulating IGF-I (+ 15 %) compared to the Control piglets. In both treatments, the circulating thyroid hormones were reduced by weaning and the levels measured at weaning were recovered earlier by the Colostrum-fed piglets compared to the Control group (P < 0.05). It is concluded that hormonal response observed after the bovine colostrum supplementation is, at least in part, consequent of the positive action of bovine colostrum on the feed intake. [less ▲]

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See detailEffect Of Bovine Colostrum Supplementation On Cytokine mRNA Expression In Weaned Piglets
Boudry, Christelle ULg; Buldgen, André; Portetelle, Daniel ULg et al

in Livestock Science (2007), 108(1-3), 295-298

The aim of this study was to evaluate the influence of a bovine colostrum supplementation on the immune Th1/Th2 response in weaned piglets. After weaning at 21 days, 21 piglets were fed daily ad libitum ... [more ▼]

The aim of this study was to evaluate the influence of a bovine colostrum supplementation on the immune Th1/Th2 response in weaned piglets. After weaning at 21 days, 21 piglets were fed daily ad libitum with a starter diet supplemented for 3 weeks with 0, 1 or 5 g of bovine colostrum. Growth performances were measured weekly. Spleen and gut-associated lymphoid tissues (GALT) (ileal Peyer’s patch (iPP), jejunum wall (JW) and mesenteric lymph nodes (MLN)) biopsies were collected on each piglet after the 3 weeks treatment and analyzed for their cytokine mRNA expression (IL-2, IL-4, IL-10, IL-12 and IFN) by RT-PCR. Growth performances were not affected by bovine colostrum (P > 0.05). In the colostrum groups, the iPP cells showed higher IL-4, IL-10 and IL-12 cytokine levels (P < 0,05), associated with a decrease of IFN-γ (P < 0,01) and no effect on IL-2 production (P > 0,05). IL-10, IL-2 and IL-12 productions increased (P < 0,05) in MLN, with no effect on IFN-γ and IL-4 levels (P > 0,05). The IL-12 production was also increased (P < 0,01) in JW cells with no modification for the other cytokine. No modification of cytokine production was observed in the spleen (P > 0,05). These results suggest an immunomodulatory effect of bovine colostrum on the GALT which answered by producing, at different levels, both Th1 pro-inflammatory cytokines - IL-2, IFN-γ and IL-12 - and Th2 anti-inflammatory cytokines - IL-4 and IL-10. This bipolarity of the Th1/Th2 response protects the weaned piglets from both allergic (food) as well as infectious (pathogens) diseases. [less ▲]

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See detailEffect Of Bovine Colostrum Supplementation On Cytokine mRNA Expression In Weaned Piglets
Boudry, Christelle ULg; Buldgen, André; Portetelle, Daniel ULg et al

in 10th International symposium on digestive physiology in pigs (2006, May)

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See detailEffect of bovine colostrums of 1st, 2nd and 3rd milking on growth performance and the immune system of newly-weaned piglets after an E. coli LPS challenge
Gauthier, Vincent ULg; Boudry, Christelle ULg; Buldgen, André

in Book of the Abstracts of the 60th Annual Meeting of the European Association for Animal Production (2009, August)

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See detailThe effect of Brand Anthropomorphism on Self-Disclosure
Gretry, Anaïs ULg; Horváth, Csilla; Belei, Nina et al

Conference (2014, October 23)

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See detailEffect of breed on Doppler echocardiographic measurements in equids
Al Haidar, A; Sandersen, Charlotte ULg; Van Erck, Emmanuelle et al

in Proceedings of the 3rd Annual Congress of the European College of Equine Internal Medicine (ECEIM) (2009)

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See detailEffect of breed, age and sex on selenium content of dromedary
Sahraoui, Naima; Boudjenah, Saliha; Dotreppe, Olivier ULg et al

in Sahraoui Journal of Camelid Science (2013), 6

The dromedary camel is able to produce meat and milk in arid conditions and its production is appreciated by the autochthon population. The aim of this study was to determine the selenium concentration in ... [more ▼]

The dromedary camel is able to produce meat and milk in arid conditions and its production is appreciated by the autochthon population. The aim of this study was to determine the selenium concentration in 61 Longissimus dorsi muscle samples representing three Algerian camel breeds (Tergui, Sahraoui or Naili breeds), the age of the selected camels ranged between 8 months and 13 years old. The muscle samples were collected from the slaughterhouse of Ouargla (South East Algeria) representing 41 males and 20 female. The average content of selenium was 0.216 mg.kg-1of wet tissue, which is higher than values currently reported in most ruminants. The level of Se was not influenced by age and sex. However, Tergui breed contained significantly higher selenium than other breeds, which may be due to diet composition intake. In conclusion, the meat from camels in Algeria is a good source of selenium, assessing its nutritional interest for human. [less ▲]

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See detailEffect of breed, sex, age and body weight on Echocardiographic Measurements in the Equine Species
Al Haidar, Ali; Farnir, Frédéric ULg; Deleuze, Stefan ULg et al

in Research in Veterinary Science (2013), In press

Little is known about the effect of various animal's signalment variables on echocardiographic reference values in the equine species. This study was performed to evaluate the effect of sex, breed, age ... [more ▼]

Little is known about the effect of various animal's signalment variables on echocardiographic reference values in the equine species. This study was performed to evaluate the effect of sex, breed, age and body weight (BW) on echocardiographic measurements in the equine species. Echocardiography was performed on 212 ponies or horses of various breeds, aged from 1 day to 37 years old (mean ± SD: 7.8 ± 5.8 years), BW 38-890 kg (mean ± SD: 421 ± 133 Kg), and free of cardiac disease. Fifty of those animals aged from 2 months to 35 years old (mean ± SD: 11.6 ± 6.4 years old); BW 77-662 kg (mean ± SD: 436 ± 135 kg) were also examined using the pulsed-wave Doppler mode. Standard two-dimensional and M-mode echocardiography were performed on all animals. Standard pulsed-wave Doppler examination of each cardiac valve was performed on the 50 first examined animals. Data were analysed using a general linear model including the effect of sex, age, breed and BW after logarithmic transformation of the data. Therefore, the same analysis was performed separately on animals aged  2 years-old and on older animals. All dimensional echocardiographic measurements were significantly affected by BW and most of them were significantly affected by breed, but not by sex. Only the aortic and the pulmonary artery internal diameter were significantly affected by age. None of the Doppler measurements were significantly affected by the tested variables. In conclusion, in the equine species, dimensional echocardiographic reference values should be established using regression equations as a function of BW, which could increase the diagnostic value of this leading technique in equine cardiology. Breed could also have an effect on those measurements. [less ▲]

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See detailEffect of brivaracetam on CYP3A activity, measured by oral midazolam.
Stockis, Armel; Watanabe, Shikiko; Scheen, André ULg

in Journal of clinical pharmacology (2014)

Brivaracetam is a synaptic vesicle protein 2A ligand in phase III development for epilepsy. A phase I, open-label, randomized study was conducted in 42 healthy male participants to assess the effect of ... [more ▼]

Brivaracetam is a synaptic vesicle protein 2A ligand in phase III development for epilepsy. A phase I, open-label, randomized study was conducted in 42 healthy male participants to assess the effect of brivaracetam on CYP3A activity using midazolam as a probe. Participants were randomized to oral brivaracetam 5, 50, or 150 mg/day from Day 8 to Day 14. A single oral dose (7.5 mg) of midazolam was administered on Days 1, 13, and 20, and full pharmacokinetic profiles were obtained. For all brivaracetam doses, the areas under the plasma concentration-time curves from 0 to infinity (AUCinf ) for midazolam and 1'-hydroxymidazolam were similar on Days 13 and 20 compared with Day 1. Following brivaracetam 150 mg/day, the Day 13/Day 1 AUCinf ratio (90% confidence interval) was 1.09 (0.97, 1.21) and 1.04 (0.93, 1.17) for midazolam and 1'-hydroxymidazolam, respectively. For the Day 20/Day 1 comparison, the corresponding AUCinf ratios were 1.10 (0.98, 1.23) and 1.07 (0.97, 1.18). Maximum midazolam plasma concentration was increased on both Day 13 and Day 20 vs. Day 1 but the relevance of this finding was unclear. This study indicates that brivaracetam up to 150 mg/day has no significant inducing or inhibiting effect on CYP3A activity. [less ▲]

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See detailEffect of bronchoalveolar lavage on lung function in healthy cats assessed by plethysmography
Kirschvink, N.; Vincke, G.; Marville, M. et al

in 20th Veterinary Comparative Respiratory Society - Boston, Massachussetts - USA - Octobre 2002 (2002, October)

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See detailEffect of butorphanol tartrate on shock-related discomfort during internal atrial defibrillation.
Timmermans, Carl; Rodriguez, L M; Ayers, G M et al

in Circulation (1999), 99(14), 1837-42

BACKGROUND: In patients with atrial fibrillation, intracardiac atrial defibrillation causes discomfort. An easily applicable, short-acting analgesic and anxiolytic drug would increase acceptability of ... [more ▼]

BACKGROUND: In patients with atrial fibrillation, intracardiac atrial defibrillation causes discomfort. An easily applicable, short-acting analgesic and anxiolytic drug would increase acceptability of this new treatment mode. METHODS AND RESULTS: In a double-blind, placebo-controlled manner, the effect of intranasal butorphanol, an opioid, was evaluated in 47 patients with the use of a step-up internal atrial defibrillation protocol (stage I). On request, additional butorphanol was administered and the step-up protocol continued (stage II). Thereafter, if necessary, patients were intravenously sedated (stage III). After each shock, the McGill Pain Questionnaire was used to obtain a sensory (S), affective (A), evaluative (E), and total (T) pain rating index (PRI) and a visual analogue scale analyzing pain (VAS-P) and fear (VAS-F). For every patient, the slope of each pain or fear parameter against the shock number was calculated and individual slopes were averaged for the placebo and butorphanol group. All patients were cardioverted at a mean threshold of 4.4+/-3.3 J. Comparing both patient groups for stage II, the mean slopes for PRI-T (P=0.0099), PRI-S (P=0.019), and PRI-E (P=0.015) became significantly lower in the butorphanol group than in the placebo group. Comparing patients who received the same shock intensity ending stage I and going to stage II, in those patients randomized to placebo the mean VAS-P (P=0.023), PRI-T (P=0. 029), PRI-S (P=0.030), and PRI-E (P=0.023) became significantly lower after butorphanol administration. CONCLUSIONS: During a step-up internal atrial defibrillation protocol, intranasal butorphanol decreased or stabilized the value of several pain variables and did not affect fear. Of the 3 qualitative components of pain, only the affective component was not influenced by butorphanol. The PRI evaluated pain more accurately than the VAS. [less ▲]

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See detailEffect of Calcitonin on Bone Mass and Fracture Rates
Reginster, Jean-Yves ULg

in American Journal of Medicine (1991), 91(5B), 19-22

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See detailEffect of calving interval on the economic results of dairy farms based on their typology.
Dalcq, Anne-Catherine ULg; Beckers, Yves ULg; Wyzen, Benoit et al

Conference (2015, July 15)

The calving interval (CI) can influence the milk production (MP) and the economic results of a farm. This research aimed to highlight the most economically important CI, on the basis of the accounts of ... [more ▼]

The calving interval (CI) can influence the milk production (MP) and the economic results of a farm. This research aimed to highlight the most economically important CI, on the basis of the accounts of breeders. The data set contained 1,318 accounts spread between 2007 and 2012. Technical information such as mean CI of the herd, percent of cows with a CI of less than 380 d (m380), between 380 and 419 d (e380419), between 420 and 459 d (e420459) and more than 459 d (p459), mean MP of the herd; as well as typological information such as quantity of equivalent concentrate (CC), number of ares of grass (GR) and of corn silage (CS) per livestock unit (LU); and economic information such as mean gross margin per cow were available. The relation between CI and the gross margin showed that if a single economic optimum of CI cannot be determined, this optimum could depend on the typology of the farm. Therefore, 4 groups were created by using a multiple correspondence analysis, including quantity of equivalent CC, number of ares of GR and of CS per LU as variables. The first group was the most intensive one with a feeding based mostly on CC and CS; the second group was similar but less intensive. The third group was the most extensive with high GR consumption. The fourth group was characterized by a near absence of CS but more CC. Moreover, m380, e380420, e420459, p459 were transformed from quantitative to qualitative variables by using numerical classification. A qualitative variable CI profile was created as a summary of all these variables. In each group, MP was modeled using the different CI variables. The assumption behind this modeling was that for a typological profile, the breeder must have the highest MP to maximize the gross margin. These models showed that MP is maximized when p459 is lower than 26%, lower than 37%, above 27% for the group 1, 2, 3 respectively. For the group 4, the model with the variable CI profile suggested that the economic optimum of CI is intermediate. These results underlined that the economic optimum of CI is related to the typology of the considered farm. Studying individual data is a perspective to determine more precisely CI with the best economic results. [less ▲]

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See detailEffect of candesartan cilexetil and angiotensin-converting enzyme inhibitor therapy on treatment adherence in hypertension
Krzesinski, Jean-Marie ULg; Lins, R.; Vandenhoven, G. et al

in Journal of Hypertension (2001), 19

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See detailEffect of carbohydrate composition in barley and oat cultivars on microbial ecophysiology and the proliferation of Salmonella enterica in an in vitro model of the porcine gastrointestinal tract
Pieper, Robert; Bindelle, Jérôme ULg; Rossnagel, Brian et al

in Applied and Environmental Microbiology (2009), 75(22), 7000-7016

The influence of the carbohydrate (CHO) composition of cereal cultivars on microbial ecophysiology was studied using an in vitro model of the porcine gastrointestinal tract. Ten hull-less barley cultivars ... [more ▼]

The influence of the carbohydrate (CHO) composition of cereal cultivars on microbial ecophysiology was studied using an in vitro model of the porcine gastrointestinal tract. Ten hull-less barley cultivars, six barley cultivars with hulls, six oat cultivars, and six oat groats that differed in beta-glucan, nonstarch polysaccharide (NSP), and starch contents and starch type were hydrolyzed enzymatically and incubated for 72 h with pig feces. Fermentation kinetics were modeled, and microbial compositions and short-chain fatty acid (SCFA) profiles were analyzed using terminal restriction fragment length polymorphism and gas chromatography. Cluster analysis and canonical ordination revealed different effects on fermentation and microbial ecology depending on the type of CHO and cultivar. First, in cultivars of barley with hulls and oats, the cellulose and insoluble NSP contents (i) increased Ruminococcus flavefaciens-like and Clostridium xylanolyticum-like phylotypes, (ii) increased acetate production, and (iii) decreased fermentation activity. Second, in hull-less barley cultivars the beta-glucan, amylose, amylopectin, crude protein, and soluble NSP contents determined the microbial community composition and activity as follows: (i) the amylose contents of the hull-less barley varieties increased the butyrate production and the abundance of Clostridium butyricum-like phylotypes, (ii) the beta-glucan content determined the total amounts of SCFA, and (iii) the amylopectin and starch contents affected the abundance of Clostridium ramosum-like phylotypes, members of Clostridium cluster XIVa, and Bacteroides-like bacteria. Finally, the effect of CHO on proliferation of Salmonella enterica in the model was determined. Salmonella cell counts were not affected, but the relative proportion of Salmonella decreased with hull-less barley cultivars and increased with oat cultivars as revealed by quantitative PCR. Our results shed light on the complex interactions of cereal CHO with intestinal bacterial ecophysiology and the possible impact on host health. [less ▲]

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