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See detailEngineering of poly(2-oxazoline)s for a potential use in biomedical applications
Legros, Camille ULg

Doctoral thesis (2014)

This PhD work is based on the design of poly(2-oxazoline) (POx) hydrogels and nanogels, by chemical or physical cross-linking, aimed to be used for biomedical applications. Nanogels were first prepared in ... [more ▼]

This PhD work is based on the design of poly(2-oxazoline) (POx) hydrogels and nanogels, by chemical or physical cross-linking, aimed to be used for biomedical applications. Nanogels were first prepared in dilute media and in inverse emulsion based on a statistical copolymer made of 2-ethyl-2-oxazoline and ethylene imine units. These stimuli-responsive nanogels were swelling in acidic media and were cleaved in reductive environment. They proved to be non-cytotoxic and act as protein repellent. Second, a reactive platform based on a statistical POx polymer bearing aldehyde functionalities was engineered, enabling the synthesis of graft and cross-linked POx. Last, a block copolymer made of 2-methyl- and 2-isopropyl-2- oxazoline units, proved to self-assemble into micelles when heated above its LCST, for a short period of time (< 1h30). When annealed for a longer time (> 1h30), crystallization-driven self-assembly led to the formation of different morphologies (fiber rods and cross-linked micelles). [less ▲]

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See detailEngineering resistance to geminiviruses--review and perspectives.
Vanderschuren, Hervé ULg; Stupak, Martin; Futterer, Johannes et al

in Plant biotechnology journal (2007), 5(2), 207-20

Following the conceptual development of virus resistance strategies ranging from coat protein-mediated interference of virus propagation to RNA-mediated virus gene silencing, much progress has been ... [more ▼]

Following the conceptual development of virus resistance strategies ranging from coat protein-mediated interference of virus propagation to RNA-mediated virus gene silencing, much progress has been achieved to protect plants against RNA and DNA virus infections. Geminiviruses are a major threat to world agriculture, and breeding resistant crops against these DNA viruses is one of the major challenges faced by plant virologists and biotechnologists. In this article, we review the most recent transgene-based approaches that have been developed to achieve durable geminivirus resistance. Although most of the strategies have been tested in model plant systems, they are ready to be adopted for the protection of crop plants. Furthermore, a better understanding of geminivirus gene and protein functions, as well as the native immune system which protects plants against viruses, will allow us to develop novel tools to expand our current capacity to stabilize crop production in geminivirus epidemic zones. [less ▲]

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See detailEngineering RNA-mediated resistance to geminiviruses in cassava
Vanderschuren, Hervé ULg

Doctoral thesis (2007)

Cassava mosaic disease (CMD) is the most important disease affecting cassava in Africa. The disease is caused by several whitefly-transmitted geminivirus species. The increasing impact of geminivirus ... [more ▼]

Cassava mosaic disease (CMD) is the most important disease affecting cassava in Africa. The disease is caused by several whitefly-transmitted geminivirus species. The increasing impact of geminivirus-caused diseases on cassava production due to the recent pandemics has urged the scientific community to provide stable virus resistance in cassava. Advances in engineering virus resistance via RNA-based strategies have opened promising perspectives for the production of transgenic geminivirus resistant plants. In this thesis, three RNA-based strategies are developed to improve the resistance to African cassava mosaic virus (ACMV) in transgenic cassava. The first strategy was based on expression of antisense viral sequences. Three different viral coding sequences were targeted and several transgenic cassava lines expressing antisense viral sequences were ACMV resistant. The second strategy was to express intron hairpin double-stranded RNAs (dsRNAs) homologous to ACMV bidirectional Promoter. Transgenic cassava lines expressing small dsRNAs homologous to the ACMV promoter were not completely immune to ACMV infection but showed an enhanced recovery phenotype as cornpared to the infected wild-type cassava plants. The third strategy relied on the expression of intron hairpin dsRNAs homologousto viral coding sequences. Transgenic cassava lines expressing high levels of small RNAs homologous to the viral coding sequences were immune under ACMV infection tests in which virus load had been sufficient to break resistance elaborated with the first two strategies. This work demonstrated that ACMV resistance could be achieved in cassava via an RNA-based approach and that the strategy used (i.e. antisense RNA, hairpin dsRNA against non-coding viral sequence, hairpin dsRNA against viral coding sequences) had an impact on the resistance level. [less ▲]

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See detailEngineering the stability of a cold-active alpha-amylase
D'Amico, Salvino; Gerday, Charles ULg; Feller, Georges ULg

Poster (1999)

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See detailEngineering three-dimensional chains of porous nanoballs from a 1,2,4-triazole-carboxylate supramolecular synthon
Naik, A. D.; Dǐrtu, M. M.; Léonard, Alexandre ULg et al

in Crystal Growth & Design (2010), 10(4), 1798-1807

Glycine ethyl ester was recruited in an amine exchange process based on a transamination to afford ethyl 4H-1,2,4-triazol-4-yl-acetate (L1). The acid hydrolysis of this molecule leads to quantitative ... [more ▼]

Glycine ethyl ester was recruited in an amine exchange process based on a transamination to afford ethyl 4H-1,2,4-triazol-4-yl-acetate (L1). The acid hydrolysis of this molecule leads to quantitative isolation of 4H-1,2,4-triazol-4-yl acetic acid (L2). This versatile synthon crystallizes in a noncentrosymmetric orthorhombic space group (Fdd2) with Z = 16. This crystal structure is the first one for a 1,2,4-triazole ligand constructed from an amino acid derivative. The strong intermolecular hydrogen bonding O-HN (2.570(3)Å) connects molecules into infinite one-dimensional chains running parallel to the b axis, and the structure is further extended by numerous but moderate strength hydrogen bonds (C-HO). Prominent features of L2 are the presence of diverse potential coordinating groups such as carboxylic acid and triazole on the same framework as well as the inherent flexibility of the ligand backbone. Reaction of L1 or L2 with aq. Cu(BF 4) 2 in aq. DMF gives dark blue crystals which crystallize in a noncentrosymmetric, cubic space group (I4̌3m) and which were formulated as [Cu 3(μ 3-O)(L2) 3(H 2O) 3]BF 4H 2O (C1). The self-assembly of C 3-symmetric, μ 3-oxo bridged triangular tricopper secondary building blocks (SBB) formed an unique architecture which encompasses voluminous nanoball voids of 1 nm. The total solvent accessible volume is 4477.5 Å 3 which accounts for 48% of the cell volume. The crystal network stability was studied by thermogravimetric analysis (TGA)'differential thermal analysis (DTA) and scanning electron microscopy (SEM) analyses. Sorption properties and gas storage capacities were measured by BET. C1 shows no preference for N 2(g), but a reversible H 2(g) uptake of 21 cm 3/g was observed. Morphology analysis by SEM on single crystals of C1 shows "ultrawellś of square shape irregularly located on the surface, whose origin is due to desolvation or crystal defects. Mercury porosimetry measurements reveal pore size distribution with a diameter ranging from 350 nm to 2.3 μm © 2010 American Chemical Society. [less ▲]

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See detailEnglish and French Canadians, Flemish and Francophone Belgians. The Linguistic Composition of the Canadian and Belgian Federal Cabinet
Reuchamps, Min ULg

Conference (2007, April 27)

In divided societies, such as Belgium and Canada, the federal principle and consociational power-sharing have been implemented in order to accommodate ethno-linguistic communities. The combination of ... [more ▼]

In divided societies, such as Belgium and Canada, the federal principle and consociational power-sharing have been implemented in order to accommodate ethno-linguistic communities. The combination of Daniel Elazar’s seminal work on federalism in plural societies and of Arend Lijphart’s on consociationalism offers a theoretical framework which can be usefully applied to study the distribution of power between the two main ethno-linguistic communities at the highest level of the state. Using the existing “model of points” and the author’s own “model of the weight of ministerial portfolios”, this paper explores the linguistic composition of the federal governments in both countries over the last thirty years (1970-2006). Whereas the Belgian Constitution has required since 1970 that the federal cabinet be staffed by an equal number of Flemish and Francophone ministers, the Canadian Constitution does not require such a linguistic parity and therefore leaves a greater freedom for the composition of the government. On this background, two logics may explain the linguistic composition in the two cases: a logic of transaction between the two main communities and a logic of representation. The paper opens, on the one hand, with the elaboration of the theoretical framework combining the works of Elazar and Lijphart and, on the other hand, with the construction of the two models. The framework and the models are applied to each case, emphasizing the logic of transaction and the logic of representation. On the basis of this examination, this paper concludes by suggesting that Flemish and Francophone Belgians as well and English and French Canadians benefit from the composition of the federal cabinet. The conclusion opens—new—ways and means to hinder political tensions in plural societies through the institutional arrangement. [less ▲]

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See detailEnglish and Spanish Size Noun-constructions, a locus of ongoing grammaticalization
Brems, Lieselotte ULg; Verveckken, Katrien

Conference (2008)

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See detailEnglish and Spanish Size Noun-constructions, a locus of ongoing grammaticalization
Brems, Lieselotte ULg; Verveckken, Katrien

Conference (2008)

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See detailEnglish language immersion in french-speaking children : does learning to read have an impact on the subsequent acquisition of french orthographic code ?
Nicolay, Anne-Catherine ULg; Fantauzzi, A.; Sadzot, Agnès ULg et al

Poster (2006, May 19)

Apprendre à lire dans une langue n’interfère pas avec l’apprentissage de la lecture dans une autre langue mais prépare plutôt le terrain pour apprendre à lire dans une autre langue. Comme dans le langage ... [more ▼]

Apprendre à lire dans une langue n’interfère pas avec l’apprentissage de la lecture dans une autre langue mais prépare plutôt le terrain pour apprendre à lire dans une autre langue. Comme dans le langage oral, il peut y avoir quelques « mixing » de prononciation au niveau des mots qui disparaissent progressivement au fur et à mesure que les langues se compartimentalisent. Avec le temps, l’enfant apprendra également que des mots qui s’écrivent de la même manière dans les deux langues peuvent se prononcer de manière différente. Une recherche menée sur des enfants francophones Belges suivant un programme d’immersion scolaire en anglais et ayant appris à lire en anglais confirment ces observations. 150 enfants âgés de 7 à 12 ans fréquentant ce programme ont été testés sur leurs compétences en lecture du français (décodage et compréhension). Leurs performances (type et nombre d’erreurs, vitesse de lecture) ont été comparées à celles d’enfants francophones fréquentant un enseignement unilingue. Leurs habiletés métaphonologiques (manipulation de la rime et du phonème) ont également été testées. [less ▲]

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See detailEnglish Renaissance Lyrics
Delrez, Marc ULg

Learning material (2004)

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See detailL'engoument pour la "Cène" de Léonard de Vinci à la cour de France, sous les règnes de Louis XII et de François Ier
Fagnart, Laure ULg

in Bulletin des amis du château et des musées de Blois (2002), 33

Cette contribution présente les copies de la "Cène" de Léonard de Vinci qui ont été réalisées à la demande de Français dans la première moitié du XVIe siècle. Elle s’attache à comprendre comment et ... [more ▼]

Cette contribution présente les copies de la "Cène" de Léonard de Vinci qui ont été réalisées à la demande de Français dans la première moitié du XVIe siècle. Elle s’attache à comprendre comment et pourquoi autant de Français, souvent en poste dans l’administration française à Milan, ont commandé des copies du chef-d’œuvre du maître italien, définissant de ce fait les mécanismes de l’engouement pour la peinture murale à la cour de France, sous les règnes de Louis XII et de François Ier. [less ▲]

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See detailEngraftment kinetics and graft failure after single umbilical cord blood transplantation using a myeloablative conditioning regimen
RUGGERI, ANNALISA; LABOPIN, MYRIAM; SORMANI, MARIA PIA et al

in Haematologica (2014), 99

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See detailLes engrais enrichis en sélénium: une alternative pour améliorer le statut en sélénium du bovin
Cabaraux, Jean-François ULg; Dotreppe, Olivier ULg; Hornick, Jean-Luc ULg et al

Article for general public (2006)

Le Sélénium (Se) est un oligo-élément indispensable au bon fonctionnement de l'organisme, notamment chez le bovin. Différents éléments plaident pour l’existence de déficits en Se dans le cheptel bovin et ... [more ▼]

Le Sélénium (Se) est un oligo-élément indispensable au bon fonctionnement de l'organisme, notamment chez le bovin. Différents éléments plaident pour l’existence de déficits en Se dans le cheptel bovin et particulièrement dans les troupeaux allaitants. Solutions injectables, bolus, supplémentation des rations… différentes méthodes permettent d’assurer un statut en Se correct chez l’animal. Une autre alternative consiste à enrichir les aliments produits au niveau de l’exploitation en utilisant des engrais enrichis en Se. Le Service de Nutrition de la Faculté de Médecine Vétérinaire a testé l’effet de ce type d’engrais sur la teneur en Se dans les aliments produits et sur le statut Se d’un troupeau de vaches allaitantes [less ▲]

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See detailL'engraissement de la vache de réforme Blan-Bleu Belge
Cabaraux, Jean-François ULg

Master of advanced studies dissertation (2001)

Detailed reference viewed: 64 (12 ULg)
See detailEngraissement du taurillon Blanc Bleu Belge culard. Enseignements pratiques
Raskin, Pascale; Van Eenaeme, Christian ULg; Minet, Vincent et al

Book published by Ministère des Classes Moyennes et de l'Agriculture - 1ère édition, mai 1997 (1997)

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See detailEngraissement du taurillon Blanc-Bleu belge
Minet, Vincent; Van Eenaeme, Christian ULg; Raskin, Pascale et al

in Agricontact (1997), 291

Detailed reference viewed: 103 (5 ULg)